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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals

Streptomycin

Historical source. Current clinical review is incomplete. This monograph will be updated in the future.

Streptomycin (opens in a new tab)Original source URL: https://globalrph.com/dilution/streptomycin/ | Retrieved 2026-11-04

Source dates, location and integrity

This historical article is separate from the reviewed claim cards. Product formulations and source dates may differ.

Original source URL
https://globalrph.com/dilution/streptomycin/ (opens in a new tab)
Source date
Not established in the retrieved source
Retrieved
2026-11-04T19:50:48.442245+00:00
Source location
div.post-content
Packaged content SHA-256
12d007310b1dd1ab000a233d3254df1a6c83d5403ce7f94ce167c4853a5aed10
Original response SHA-256
78a243fb23a92c9f8472c24e20703d94cc330c1a06f21f743c7ff74d143c7a91
Source body SHA-256
e88358ff36b41b82b52e3831dbdfe2d870e2603602e05b6ea0e2448275b3a779

STREPTOMYCIN

The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this document shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.

Usual Diluents

NS, D5W

Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]

[Usual dose] [100 ml] [30-60 min]

(Not approved for IV use, however, has been used in patients with insufficient muscle mass.)

Stability / Miscellaneous

Label: Refrigerate
Dosing: (Tuberculosis): 15 mg/kg (Max=1 gram) IM once daily or 25-30 mg/kg administered twice weekly (maximum 1.5 grams/dose) or three times weekly (Maximum 1 gram/dose).

Streptomycin usually replaces ethambutol in the 4 drug regimen [INH, Rifampin, Pyrazinamide, streptomycin].

[CRCL: 10-50// q24-72h or 750mg 2 to 3x/week]
[CRCL < 10// q72-96hrs instead of once daily]

Separate renal reference: Open Renal Dosing Master (opens in a new tab)

Serum level monitoring: Adjust dose to maintain a trough < 4 mcg/ml.

Source: [package insert]

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