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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals

Hydralazine

Historical source. Current clinical review is incomplete. This monograph will be updated in the future.

Hydralazine (opens in a new tab)Original source URL: https://globalrph.com/dilution/hydralazine/ | Retrieved 2026-11-04

Source dates, location and integrity

This historical article is separate from the reviewed claim cards. Product formulations and source dates may differ.

Original source URL
https://globalrph.com/dilution/hydralazine/ (opens in a new tab)
Source date
Not established in the retrieved source
Retrieved
2026-11-04T19:46:33.974212+00:00
Source location
div.post-content
Packaged content SHA-256
b72590a88fb8565a14e119f7dbffc9bb3d308e69a0243366a330fa418381b69f
Original response SHA-256
50ff0d35532f9e3511fc0a77d50cbc3b70d95dce89e34d107328d4c34635c456
Source body SHA-256
89455951a85e195c27e2c345a9ca8bffbeb6da67078dbf2a828a82c9744736bd

HYDRALAZINE

The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this document shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.

Usual Diluents

NS

Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]

[0 to 20 mg] [50 ml] [30 min]
[21 to 40 mg] [100 ml] [30 min]
[>40 mg] [250 ml] [60 min or longer]

Monitor BP q5min during initial infusion.

Stability / Miscellaneous

Manufacturer recommends IM or IV push.

Usual dosage: 10 to 40 mg IV q4-6h prn. May be given q20-30 minutes (until adequate response) for the treatment of severe hypertension. IV push (rate): 10 mg/min.

Label: Do not refrigerate. Stability: 24 hours room temperature.

DOSAGE AND ADMINISTRATION
When there is urgent need, therapy in the hospitalized patient may be initiated intramuscularly or as a rapid intravenous bolus injection directly into the vein. Hydralazine hydrochloride injection should be used only when the drug cannot be given orally. The usual dose is 20-40 mg, repeated as necessary.

Certain patients (especially those with marked renal damage) may require a lower dose. Blood pressure should be checked frequently. It may begin to fall within a few minutes after injection, with the average maximal decrease occurring in 10-80 minutes. In cases where there has been increased intracranial pressure, lowering the blood pressure may increase cerebral ischemia. Most patients can be transferred to oral hydralazine hydrochloride within 24-48 hours.

The product should be used immediately after the vial is opened. It should not be added to infusion solutions. Hydralazine hydrochloride injection may discolor upon contact with metal; discolored solutions should be discarded.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Source: [package insert]

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