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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Medication reference

Rocuronium

Monograph awaiting updateThis monograph will be updated in the future.

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No original site article was mapped to this record. The available historical structured fields and official-source links are retained.

Historical first look: uses, mechanism, dosing context, and administration

Recovered v5.1 source content; historical, awaiting current review.

Id
rocuronium
Source IDH51-60A02F162BFC6F1209EA8D26
Generic name
Rocuronium
Source IDH51-1BEDF25DAB76466C133B54C7
Class
Neuromuscular blockade
Source IDH51-A9CA7AC7FDEF7B52FC0055FD
Subclass
Nondepolarizing neuromuscular blocker
Source IDH51-7CFEBBFD49E9CCADF77BEBFF
Primary uses
  1. Rapid-sequence or routine intubation
    Source IDH51-B587A6B8BB10AF6608DD2A71
  2. Surgical paralysis
    Source IDH51-64EC649B04123A0A98E5F091
  3. ICU paralysis
    Source IDH51-8BF9CA7701EA58C9A266DA4E
Mechanism
Competitively blocks nicotinic Nm receptors at the neuromuscular junction.
Source IDH51-E0CA89FAF3C859517BFB6D82
Mechanism level
drug_specific
Source IDH51-04D5A71D7FB7017A7E565263
Basic dosing orientation
Adult bolus | Existing preparation record; use current package insert for indication-specific selection | Weight- and scenario-specific dose | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult infusion | Existing preparation record; use current package insert for indication-specific selection | Prepare standardized bag or syringe | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion
Source IDH51-09428A83D2AE068ACAB55151
Administration orientation
Rapid IV bolus for intubation; Titrate by mcg/kg/min; 10 mg/mL; Rapid IV bolus
Source IDH51-09E12709BB756659CB82D3CA
Renal and population orientation
Separate renal reference: Open Renal Dosing Master (opens in a new tab)No routine renal adjustment is commonly used for many indications, but verify the current label and clinical context.
Source IDH51-0A4889742A1EFB641E46BD27
Key safety orientation
  1. Awareness while paralyzed if sedation fails.
    Source IDH51-37ACD4D3D7CB24F049C908ED
  2. Anaphylaxis and prolonged weakness.
    Source IDH51-5E59DABE1D07AB731B0EAED0
  3. Requires immediate airway and ventilation capability.
    Source IDH51-D8FF203844AD720ECC86DF8F
Coverage path
structured_local_snapshot
Source IDH51-58544BA70496A6C73A07F7AF
Coverage path label
Structured GlobalRPh route snapshot
Source IDH51-B98DD96491FB230C11D2ED86
Review note
First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
Source IDH51-8615B4D7505B690888E92896
Search text
Rocuronium Neuromuscular blockade Nondepolarizing neuromuscular blocker Rapid-sequence or routine intubation Surgical paralysis ICU paralysis Competitively blocks nicotinic Nm receptors at the neuromuscular junction. Adult bolus | Existing preparation record; use current package insert for indication-specific selection | Weight- and scenario-specific dose | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult infusion | Existing preparation record; use current package insert for indication-specific selection | Prepare standardized bag or syringe | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion Rapid IV bolus for intubation; Titrate by mcg/kg/min; 10 mg/mL; Rapid IV bolus No routine renal adjustment is commonly used for many indications, but verify the current label and clinical context. Awareness while paralyzed if sedation fails. Anaphylaxis and prolonged weakness. Requires immediate airway and ventilation capability. Structured GlobalRPh route snapshot
Source IDH51-71286EA9E0C2E7AE5DC8ACE9
Official access mode
search
Source IDH51-0F1AA78091E356FE34E1905D
Official search query
Rocuronium
Source IDH51-FBD487FF350F915084DA6A55
Official access reason
A source-backed DailyMed search is available; select and confirm the exact IV product.
Source IDH51-AB6401BFBBF2F574E4179F21
Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • Retrievable exact-product SPL XML with version, revision, retrieval date and reproducible hash
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
no_routine_adjustment_identified
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.

      No separate structured rows were bundled for dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical dilution and intermittent infusion preparation

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationAmountReconstitutionDiluentFinal volumeConcentrationRateStabilityNotes
      Source IDH51-143C02E6A8E867EB714F448B
      Adult bolus
      Source IDH51-0C683023227A6857ACC2F467
      		Weight- and scenario-specific dose
      Source IDH51-B17A814778F4AC85F5F6BB5B
      		Ready-to-use 10 mg/mL solution.
      Source IDH51-0B0F4044EFFE627CF303C20E
      		May use undiluted
      Source IDH51-44B4509E6D07624EDEA8BF72
      		Syringe
      Source IDH51-323D940D0DBF7874FF8634D4
      		10 mg/mL
      Source IDH51-E70CAFD72AB0F0A3E4162497
      		Rapid IV bolus for intubation
      Source IDH51-AA2D44F4DC37D93CBEC06C2B
      		Use the shorter of current product labeling, validated stability data, and the applicable USP <797> sterility-based BUD ceiling.
      Source IDH51-6B2BEADA1BED3751A66F3BD5
      		Ensure complete sedation and analgesia before paralysis.
      Source IDH51-C19DA71701986A5DEF144449
      Source IDH51-AB22975035D0DAAF5A10BCB5
      Adult infusion
      Source IDH51-8B1561D49D70A67A61B5D066
      		Prepare standardized bag or syringe
      Source IDH51-DACBFF6E8F39BCFB73371F2A
      		Dilute per institutional standard.
      Source IDH51-AE1C2558BDFA765ACBD41520
      		NS or D5W
      Source IDH51-A8D92E8F798D1083558848B8
      		50 to 100 mL
      Source IDH51-42A37A7285937910F0FF6CBB
      		Commonly 1 to 5 mg/mL
      Source IDH51-521EBFE805F288C5913B7B3F
      		Titrate by mcg/kg/min
      Source IDH51-D87820FE5D84AA06A5F6E3A2
      		Use the shorter of current product labeling, validated stability data, and the applicable USP <797> sterility-based BUD ceiling.
      Source IDH51-4E685DDAF5D5C26288CA40D3
      		Use train-of-four plus clinical assessment.
      Source IDH51-71DDCB08065833D96EA46FBB

      Historical IV-push guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationDose scopeConcentrationRateStatusNotes
      Source IDH51-BABBB283BF2AD83A72A30306
      Adult and pediatric
      Source IDH51-2CD98F04660449FE12A05263
      		Weight-based intubation or maintenance bolus
      Source IDH51-C5AB80A8549545014F96ACD0
      		10 mg/mL
      Source IDH51-679E18A5DA76DBC37A635148
      		Rapid IV bolus
      Source IDH51-1D48D80569E8D9CEFFE39D12
      		Anesthesia/critical-care protocol only
      Source IDH51-6E3E2B383F70EE70A54D935E
      		Paralysis does not provide sedation, amnesia, or analgesia.
      Source IDH51-E950BC41DB2CE3459D7EA268

      Historical continuous-infusion guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationStandard concentrationInitial rateTitrationMaximumNotes
      Source IDH51-B7488D8ADAA766807C6D2337
      Adult
      Source IDH51-3F5D1FC943BFE5CB302BEE78
      		1 to 5 mg/mL
      Source IDH51-046D03CAC5AF84DC53865E7F
      		Commonly 5 to 10 mcg/kg/min after bolus
      Source IDH51-FD4BEF1556C0226FB1639DB6
      		Titrate to neuromuscular target
      Source IDH51-E11BFB1CDC595E6232F747D3
      		Protocol-specific
      Source IDH51-1DCBA9E7B37EBF303A2DDF83
      		Daily interruption should be considered when clinically appropriate.
      Source IDH51-8A0FCACD4D01DEE7DB182516

      Historical indication and population dosing

      Recovered tables and source-separated snapshots; full clinical revalidation remains pending.

      Existing dose and route snapshots

      RoutePopulationIndicationDoseIntervalDurationAdministrationSource levelNotes
      Source IDH51-37A6524FEE72DA04A8C7C2EC
      IV infusion
      Source IDH51-A2E59232685C96639BF32D6D
      		Adult bolus
      Source IDH51-2F2FE44CE5DB6F1A05668DC6
      		Existing preparation record; use current package insert for indication-specific selection
      Source IDH51-29FB46709AC5496EC7C19EB4
      		Weight- and scenario-specific dose
      Source IDH51-DC5EA77389DE444F3D8E8A0B
      		Not normalized in the preparation record
      Source IDH51-A7560249586F313FCDABD605
      		See current package insert and professional guidance
      Source IDH51-3B6E10E5A5307562CB9050FD
      		Rapid IV bolus for intubation
      Source IDH51-D67A9C7F29871C00595C9868
      		Existing GlobalRPh structured preparation snapshot
      Source IDH51-820680F754DC6A059FE11FD9
      		Ensure complete sedation and analgesia before paralysis.
      Source IDH51-DFB33E1BEFDC1BB47FF7C89F
      Source IDH51-215521ED89413A1CAD70124A
      IV infusion
      Source IDH51-65AB28A9900316F26A1BF1B5
      		Adult infusion
      Source IDH51-6F6B17798FF641CC787D5BA2
      		Existing preparation record; use current package insert for indication-specific selection
      Source IDH51-6B2A2B850D3B0318B5CCE16D
      		Prepare standardized bag or syringe
      Source IDH51-C02E7648659B6210E19E21BA
      		Not normalized in the preparation record
      Source IDH51-EE017D8A2C5F9124CE321EAE
      		See current package insert and professional guidance
      Source IDH51-B0B5D8105492C63AFD7B07E0
      		Titrate by mcg/kg/min
      Source IDH51-42DDEF99F5D8376A6758A87A
      		Existing GlobalRPh structured preparation snapshot
      Source IDH51-D7D516F061313E586A49730C
      		Use train-of-four plus clinical assessment.
      Source IDH51-D37F9EBB95FAF1DDBFC7CF84
      Source IDH51-70CD229D683961DF7A20673C
      IV push
      Source IDH51-1B640B2603864546C8AC00F8
      		Adult and pediatric
      Source IDH51-06D577814909BADF28EBC40B
      		Weight-based intubation or maintenance bolus
      Source IDH51-49E2525DFFCDAD0D7685398F
      		Weight-based intubation or maintenance bolus
      Source IDH51-71494BD0F0890F7530F05AD6
      		Patient- and indication-specific
      Source IDH51-22C4AF3472852E014E7F353B
      		See current package insert
      Source IDH51-841CF14C263C5159686303DB
      		Rapid IV bolus
      Source IDH51-E3268484BD7C5B823BAD399D
      		Existing GlobalRPh IV push snapshot
      Source IDH51-A415E6B7998E66333E222A16
      		Anesthesia/critical-care protocol only Paralysis does not provide sedation, amnesia, or analgesia.
      Source IDH51-3954AFE457A9D2C3A08378AB
      Source IDH51-FC1988448CE50378F24AC0AF
      Continuous IV infusion
      Source IDH51-53E26A153BB1CF2765E62904
      		Adult
      Source IDH51-B61FD90740C6CCF4139FB399
      		Existing continuous-infusion record
      Source IDH51-2C72BEE3FBA88AD5A7248A3B
      		Commonly 5 to 10 mcg/kg/min after bolus
      Source IDH51-4036B2CCA37CE3379E81A29F
      		Continuous infusion; titration-specific
      Source IDH51-0F0CE297507940A2F7E61090
      		Clinical-response dependent
      Source IDH51-9DC49B3766D45AAF07DD1207
      		Titrate to neuromuscular target
      Source IDH51-3C5F292F31A1F19D686B5BC3
      		Existing GlobalRPh continuous-infusion snapshot
      Source IDH51-06EA9B1BE1660D7FE5B9F75D
      		Protocol-specific Daily interruption should be considered when clinically appropriate.
      Source IDH51-46EA17651E9E155CAACC7656

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      no_routine_adjustment_identified
      Source IDH51-13A49CF89AE075A0A3437D3C
      Summary
      No routine renal adjustment is commonly used for many indications, but verify the current label and clinical context.
      Source IDH51-94729FE2B9DDF945BEBB416A
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-42930DADF1B8A58887F5BA8E

      Historical Common IV uses

      Recovered v5.1 source content; historical, awaiting current review.

      1. Rapid-sequence or routine intubation
        Source IDH51-960AC03699A5D5A234E16D5F
      2. Surgical paralysis
        Source IDH51-3F45713A0D7BEEC480C540F9
      3. ICU paralysis
        Source IDH51-D4DE6C163CC9C7407BC7153B

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Awareness while paralyzed if sedation fails.
        Source IDH51-B771BCF77E008F5DD73D8E3E
      2. Anaphylaxis and prolonged weakness.
        Source IDH51-7CEFF04FA1FC6C663E696AED
      3. Requires immediate airway and ventilation capability.
        Source IDH51-E456793B29E6F29554F831EF

      Historical Monitoring

      Recovered v5.1 source content; historical, awaiting current review.

      1. Continuous ventilation and oxygenation
        Source IDH51-6239FFFD05A6AC137FCE29A0
      2. Sedation/analgesia
        Source IDH51-9ED3702742967698DB822576
      3. Quantitative neuromuscular monitoring
        Source IDH51-B7555614E0D80314603188D7
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      rocuronium
      Source IDH51-437A1742A3DA3369762F7CD6
      Generic name
      Rocuronium
      Source IDH51-27554E0D8C0A230764848C68
      Brand names
      1. Zemuron
        Source IDH51-5581ECC6E37E6AD467B7DD0D
      Class
      Neuromuscular blockade
      Source IDH51-5AD1D0B211AB2801BA8AD7B4
      Subclass
      Nondepolarizing neuromuscular blocker
      Source IDH51-4D6CB9E20771B7D76EF7EEC7
      Summary
      Paralytic agent administered by bolus or infusion only with ventilation, sedation/analgesia, and quantitative neuromuscular monitoring.
      Source IDH51-403CBFE205E3ED389DE02340
      Populations
      1. Adult
        Source IDH51-B8D3D2711CA0B98553D0BB21
      2. Pediatric
        Source IDH51-ED5060F3A0FB604FF6398225
      Evidence tier
      Core reference - verify current label
      Source IDH51-334EEE14890A23F425F993D2
      High alert
      true
      Source IDH51-9F738E912367814D35BA04E5
      Hazardous
      false
      Source IDH51-63226DE6ADD98BCC834C6C9C
      Status
      Active
      Source IDH51-CDFAD0DED321F521267E2A82
      Reviewed
      2026-08-29
      Source IDH51-88A2C566663F4E55E9C0D43E
      Version added
      1.2
      Source IDH51-A035F317CB9E641542101B82
      Sources
      LabelUrlKind
      Source IDH51-402A221E56C6B483AE95886A
      DailyMed label search
      Source IDH51-30AFF50303376A9A425F78CE
      		https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Rocuronium (opens in a new tab)
      Source IDH51-DFB1BEF3526500539F699CFB
      		Primary
      Source IDH51-0F905055EFEE09081E6A350D
      Source IDH51-F799AC5FA94B138C233760D6
      GlobalRPh legacy IV dilution monograph
      Source IDH51-6917834515D39B9841F8BBE2
      		legacy:auto
      Source IDH51-D4B29CF2BC778417CF677495
      		Legacy
      Source IDH51-DDDC52981E6643F9384CC919
      Clinical release verification
      Audit version
      3.4
      Source IDH51-7055EA87C362AEB99D39F237
      Audited on
      2026-08-30
      Source IDH51-F28DDFE0D017F8A9A1A5337B
      Level
      amber
      Source IDH51-8E689DB278FCB54A960D65B9
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-EC1718828D35363BBCEFE21A
      Exact current label candidate
      false
      Source IDH51-47A9D86EA263AB6661AD1965
      Numeric support ratio
      0
      Source IDH51-9000EBD16E8C7323B2C206DD
      Reference url count
      1
      Source IDH51-909A46C6F83B15D3A7EC3775
      Broken reference count
      0
      Source IDH51-1709C2C4F544D857633787B8
      Point of use confirmation required
      true
      Source IDH51-127CDB82B0BE9C795352907F
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-101B536995DDBC14526F31D2

      Dosing source fields

      Id
      rocuronium
      Source IDH51-BD49D9D877B548B9B402613C
      Generic name
      Rocuronium
      Source IDH51-D665A05E7147CA3A2D9EAEB5
      Coverage status
      direct_official_label_access_plus_local_snapshot
      Source IDH51-A40B4482A1EF41BE563F5915
      Package insert
      Query name
      Rocuronium
      Source IDH51-376F64DEBC617682185CC74E
      Product and route must match
      true
      Source IDH51-FEC87B034C31636C19511AAF
      Live current label enabled
      false
      Source IDH51-1F506CD43813C697ECDE96AA
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-84BC41679EC8BCDD861D8384
      Direct official label access enabled
      true
      Source IDH51-42662EECA4B3FD2B4C69418C
      Outbound server request required
      false
      Source IDH51-D9CF12AB7DF830C7798CF5A6
      Local summary status
      not_bundled
      Source IDH51-F010F7144D0EF623B6628012
      Clinical review
      Locally normalized
      false
      Source IDH51-DC22CA956F0838286CCCAD2C
      Reviewed
      2026-08-29
      Source IDH51-6C4905EA6B737F8C03CB1DD6
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-1E610C16A3A5B1C49D6420C9
      Clinical release verification
      Audit version
      3.4
      Source IDH51-F713E3395821F03433ADB48E
      Audited on
      2026-08-30
      Source IDH51-270C374070E8132FE2E2BF29
      Level
      amber
      Source IDH51-8F53933848FF06184249BC1C
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-98F528C9B2BBEFD89E68B1AE
      Exact current label candidate
      false
      Source IDH51-AF6DBD95D9CDC544E890425C
      Numeric support ratio
      0
      Source IDH51-F92632A45A54D0E0A9F8B0AB
      Reference url count
      1
      Source IDH51-55BA32B7C266641F03C9AD3D
      Broken reference count
      0
      Source IDH51-8168FACCD4A102E5616C0DB5
      Point of use confirmation required
      true
      Source IDH51-FCFCD066C5F9872812464446
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-ACBDD1CE40D09267E245C848
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      rocuronium
      Source IDH51-C6135A63E3D26AE1CDDAD887
      Name
      Rocuronium
      Source IDH51-77A4072BCE7B2BD1855FEFCD
      Brands
      Zemuron
      Source IDH51-6281A9621FDDF5B96A8232E3
      Therapeutic class
      Neuromuscular blockade
      Source IDH51-4BE7412D9111142A3AF8A0E9
      Review version
      3.1
      Source IDH51-DCC92EA442BD814C2EB45F78
      Review date
      2026-08-30
      Source IDH51-8353FB459DF6CF05443EBB2A
      Release status
      structured_record_current_label_not_confirmed
      Source IDH51-72AF65C2AA048AC014E4758D
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-7E7CB269A567AEEF0BFF04F0
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-82E7D18B38C680B15C540B4C
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-DC94744675B14EC050E7D5A6
      Reconstitution concentration
      Ready-to-use 10 mg/mL solution. Dilute per institutional standard.
      Source IDH51-C009985489C66F6ECC302DC8
      Maximum or recommended final concentration
      1 to 5 mg/mL
      Source IDH51-CD73EEC30A6459DC4E416EFC
      Appropriate standardized containers
      Syringe 50 to 100 mL
      Source IDH51-C16D36C560B154A419A40336
      Adult dosing range
      Weight- and scenario-specific dose Prepare standardized bag or syringe Weight-based intubation or maintenance bolus Commonly 5 to 10 mcg/kg/min after bolus Weight-based intubation or maintenance bolus
      Source IDH51-6179972D5E43C3422EC9695B
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-2E3A77D0E5B65477C286B818
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-2009428E2CEC52D887DD57EE
      Infusion time
      Rapid IV bolus for intubation Titrate by mcg/kg/min Rapid IV bolus Commonly 5 to 10 mcg/kg/min after bolus
      Source IDH51-5A03EA26E2E9E316F7346C9F
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-A7C144EF0D08EF92DB921E69
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-6A6E9D2C8D99A5442DBFEDE0
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-345467165A31232737A542B4
      Reconstitution concentration
      Primary
      existing_structured_record
      Source IDH51-6EB3496B2C2331860F467921
      Maximum or recommended final concentration
      Primary
      existing_structured_record
      Source IDH51-0308FEF93DE497DACF5FB237
      Appropriate standardized containers
      Primary
      existing_structured_record
      Source IDH51-311107D9FD379534FD72F44F
      Adult dosing range
      Primary
      existing_structured_record
      Source IDH51-7854ADA65C901DB0AF0F04B1
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-70505E156C8185FF4A824E4C
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-CFED6EA81B0A3C815CEC41E1
      Infusion time
      Primary
      existing_structured_record
      Source IDH51-B47B46576A9EEF8E78062CB8
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-FACEF0DF8BBC1F1E8B3A65EB
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-E4B5AB78591F7600FA9A29BF
      Population applicability
      Adult
      Applicability
      supported_or_source_present
      Source IDH51-A338A52C73634159B46E591A
      Guide generation allowed
      true
      Source IDH51-94FB6D59430DC03423D60258
      Pediatric
      Applicability
      supported_or_source_present
      Source IDH51-C1853E0D207108A3F9D93CB7
      Guide generation allowed
      false
      Source IDH51-E805104BAB378225088E1286
      Neonatal
      Applicability
      not_established
      Source IDH51-A79D641249B54B5A3E4108C7
      Guide generation allowed
      false
      Source IDH51-5B40EA5A50C7788508210D46
      Route presence
      Structured dilution
      true
      Source IDH51-4A3B55C37996816E704BA36A
      Iv push
      true
      Source IDH51-A10E08851C68F807D5383DA0
      Continuous infusion
      true
      Source IDH51-882203E6AFC71762D91AD21F
      Pediatric source
      true
      Source IDH51-E0900E1D014F332B2CFE05FA
      Neonatal source
      false
      Source IDH51-FD5E40EE96FA5BFCCE8A5935
      Legacy reference
      Status
      not_available
      Source IDH51-C6C5F1CC8ED15859DF9FF91C
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-59908A82C8F6F91FBB5C4395
      Concentration values detected
      LowHighUnitText
      Source IDH51-DFBFB4CCF701FBB574E1A011
      1
      Source IDH51-50586880B6B0D62F5EC557F2
      		5
      Source IDH51-5050A5C5E5EA32218F7BD3F7
      		mg
      Source IDH51-784EF97996E45428DA3E05B5
      		1 to 5 mg/mL
      Source IDH51-7FF7A7BE4C5FF7AFCB1C3C92
      Source files
      1. catalog.json
        Source IDH51-0250940D46E628685CC775E2
      2. dosing.json
        Source IDH51-498C8106A59D1897DF75E2DE
      3. new-in-v1.2.json
        Source IDH51-61B0F453E6EF49A32853121D
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-F55CE8824C44B724920C1216
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-437A1742A3DA3369762F7CD6catalog.json
      /records/222/id      		Historical; current review incomplete
      H51-27554E0D8C0A230764848C68catalog.json
      /records/222/generic_name      		Historical; current review incomplete
      H51-5581ECC6E37E6AD467B7DD0Dcatalog.json
      /records/222/brand_names/0      		Historical; current review incomplete
      H51-5AD1D0B211AB2801BA8AD7B4catalog.json
      /records/222/class      		Historical; current review incomplete
      H51-4D6CB9E20771B7D76EF7EEC7catalog.json
      /records/222/subclass      		Historical; current review incomplete
      H51-403CBFE205E3ED389DE02340catalog.json
      /records/222/summary      		Historical; current review incomplete
      H51-960AC03699A5D5A234E16D5Fcatalog.json
      /records/222/common_uses/0      		Historical; current review incomplete
      H51-3F45713A0D7BEEC480C540F9catalog.json
      /records/222/common_uses/1      		Historical; current review incomplete
      H51-D4DE6C163CC9C7407BC7153Bcatalog.json
      /records/222/common_uses/2      		Historical; current review incomplete
      H51-143C02E6A8E867EB714F448Bcatalog.json
      /records/222/preparations/0      		Historical; current review incomplete
      H51-0C683023227A6857ACC2F467catalog.json
      /records/222/preparations/0/population      		Historical; current review incomplete
      H51-B17A814778F4AC85F5F6BB5Bcatalog.json
      /records/222/preparations/0/amount      		Historical; current review incomplete
      H51-0B0F4044EFFE627CF303C20Ecatalog.json
      /records/222/preparations/0/reconstitution      		Historical; current review incomplete
      H51-44B4509E6D07624EDEA8BF72catalog.json
      /records/222/preparations/0/diluent      		Historical; current review incomplete
      H51-323D940D0DBF7874FF8634D4catalog.json
      /records/222/preparations/0/final_volume      		Historical; current review incomplete
      H51-E70CAFD72AB0F0A3E4162497catalog.json
      /records/222/preparations/0/concentration      		Historical; current review incomplete
      H51-AA2D44F4DC37D93CBEC06C2Bcatalog.json
      /records/222/preparations/0/rate      		Historical; current review incomplete
      H51-6B2BEADA1BED3751A66F3BD5catalog.json
      /records/222/preparations/0/stability      		Historical; current review incomplete
      H51-C19DA71701986A5DEF144449catalog.json
      /records/222/preparations/0/notes      		Historical; current review incomplete
      H51-AB22975035D0DAAF5A10BCB5catalog.json
      /records/222/preparations/1      		Historical; current review incomplete
      H51-8B1561D49D70A67A61B5D066catalog.json
      /records/222/preparations/1/population      		Historical; current review incomplete
      H51-DACBFF6E8F39BCFB73371F2Acatalog.json
      /records/222/preparations/1/amount      		Historical; current review incomplete
      H51-AE1C2558BDFA765ACBD41520catalog.json
      /records/222/preparations/1/reconstitution      		Historical; current review incomplete
      H51-A8D92E8F798D1083558848B8catalog.json
      /records/222/preparations/1/diluent      		Historical; current review incomplete
      H51-42A37A7285937910F0FF6CBBcatalog.json
      /records/222/preparations/1/final_volume      		Historical; current review incomplete
      H51-521EBFE805F288C5913B7B3Fcatalog.json
      /records/222/preparations/1/concentration      		Historical; current review incomplete
      H51-D87820FE5D84AA06A5F6E3A2catalog.json
      /records/222/preparations/1/rate      		Historical; current review incomplete
      H51-4E685DDAF5D5C26288CA40D3catalog.json
      /records/222/preparations/1/stability      		Historical; current review incomplete
      H51-71DDCB08065833D96EA46FBBcatalog.json
      /records/222/preparations/1/notes      		Historical; current review incomplete
      H51-BABBB283BF2AD83A72A30306catalog.json
      /records/222/iv_push/0      		Historical; current review incomplete
      H51-2CD98F04660449FE12A05263catalog.json
      /records/222/iv_push/0/population      		Historical; current review incomplete
      H51-C5AB80A8549545014F96ACD0catalog.json
      /records/222/iv_push/0/dose_scope      		Historical; current review incomplete
      H51-679E18A5DA76DBC37A635148catalog.json
      /records/222/iv_push/0/concentration      		Historical; current review incomplete
      H51-1D48D80569E8D9CEFFE39D12catalog.json
      /records/222/iv_push/0/rate      		Historical; current review incomplete
      H51-6E3E2B383F70EE70A54D935Ecatalog.json
      /records/222/iv_push/0/status      		Historical; current review incomplete
      H51-E950BC41DB2CE3459D7EA268catalog.json
      /records/222/iv_push/0/notes      		Historical; current review incomplete
      H51-B7488D8ADAA766807C6D2337catalog.json
      /records/222/continuous_infusions/0      		Historical; current review incomplete
      H51-3F5D1FC943BFE5CB302BEE78catalog.json
      /records/222/continuous_infusions/0/population      		Historical; current review incomplete
      H51-046D03CAC5AF84DC53865E7Fcatalog.json
      /records/222/continuous_infusions/0/standard_concentration      		Historical; current review incomplete
      H51-FD4BEF1556C0226FB1639DB6catalog.json
      /records/222/continuous_infusions/0/initial_rate      		Historical; current review incomplete
      H51-E11BFB1CDC595E6232F747D3catalog.json
      /records/222/continuous_infusions/0/titration      		Historical; current review incomplete
      H51-1DCBA9E7B37EBF303A2DDF83catalog.json
      /records/222/continuous_infusions/0/maximum      		Historical; current review incomplete
      H51-8A0FCACD4D01DEE7DB182516catalog.json
      /records/222/continuous_infusions/0/notes      		Historical; current review incomplete
      H51-B771BCF77E008F5DD73D8E3Ecatalog.json
      /records/222/warnings/0      		Historical; current review incomplete
      H51-7CEFF04FA1FC6C663E696AEDcatalog.json
      /records/222/warnings/1      		Historical; current review incomplete
      H51-E456793B29E6F29554F831EFcatalog.json
      /records/222/warnings/2      		Historical; current review incomplete
      H51-6239FFFD05A6AC137FCE29A0catalog.json
      /records/222/monitoring/0      		Historical; current review incomplete
      H51-9ED3702742967698DB822576catalog.json
      /records/222/monitoring/1      		Historical; current review incomplete
      H51-B7555614E0D80314603188D7catalog.json
      /records/222/monitoring/2      		Historical; current review incomplete
      H51-B8D3D2711CA0B98553D0BB21catalog.json
      /records/222/populations/0      		Historical; current review incomplete
      H51-ED5060F3A0FB604FF6398225catalog.json
      /records/222/populations/1      		Historical; current review incomplete
      H51-334EEE14890A23F425F993D2catalog.json
      /records/222/evidence_tier      		Historical; current review incomplete
      H51-9F738E912367814D35BA04E5catalog.json
      /records/222/high_alert      		Historical; current review incomplete
      H51-63226DE6ADD98BCC834C6C9Ccatalog.json
      /records/222/hazardous      		Historical; current review incomplete
      H51-CDFAD0DED321F521267E2A82catalog.json
      /records/222/status      		Historical; current review incomplete
      H51-88A2C566663F4E55E9C0D43Ecatalog.json
      /records/222/reviewed      		Historical; current review incomplete
      H51-A035F317CB9E641542101B82catalog.json
      /records/222/version_added      		Historical; current review incomplete
      H51-402A221E56C6B483AE95886Acatalog.json
      /records/222/sources/0      		Historical; current review incomplete
      H51-30AFF50303376A9A425F78CEcatalog.json
      /records/222/sources/0/label      		Historical; current review incomplete
      H51-DFB1BEF3526500539F699CFBcatalog.json
      /records/222/sources/0/url      		Historical; current review incomplete
      H51-0F905055EFEE09081E6A350Dcatalog.json
      /records/222/sources/0/kind      		Historical; current review incomplete
      H51-F799AC5FA94B138C233760D6catalog.json
      /records/222/sources/1      		Historical; current review incomplete
      H51-6917834515D39B9841F8BBE2catalog.json
      /records/222/sources/1/label      		Historical; current review incomplete
      H51-D4B29CF2BC778417CF677495catalog.json
      /records/222/sources/1/url      		Historical; current review incomplete
      H51-DDDC52981E6643F9384CC919catalog.json
      /records/222/sources/1/kind      		Historical; current review incomplete
      H51-5763F9E77B4BD3C1D56AED06catalog.json
      /records/222/legacy_title      		Historical; current review incomplete
      H51-7055EA87C362AEB99D39F237catalog.json
      /records/222/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-F28DDFE0D017F8A9A1A5337Bcatalog.json
      /records/222/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-8E689DB278FCB54A960D65B9catalog.json
      /records/222/clinical_release_verification/level      		Historical; current review incomplete
      H51-EC1718828D35363BBCEFE21Acatalog.json
      /records/222/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-47A9D86EA263AB6661AD1965catalog.json
      /records/222/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-EFD9B1E8F8679A8394033AD9catalog.json
      /records/222/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-7797B23BEAD760E043936050catalog.json
      /records/222/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-9000EBD16E8C7323B2C206DDcatalog.json
      /records/222/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-909A46C6F83B15D3A7EC3775catalog.json
      /records/222/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-1709C2C4F544D857633787B8catalog.json
      /records/222/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-127CDB82B0BE9C795352907Fcatalog.json
      /records/222/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-101B536995DDBC14526F31D2catalog.json
      /records/222/clinical_release_verification/note      		Historical; current review incomplete
      H51-04DD45906B5461FC9E794B4Ecatalog.json
      /records/222/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-BD49D9D877B548B9B402613Cdosing.json
      /records/222/id      		Historical; current review incomplete
      H51-D665A05E7147CA3A2D9EAEB5dosing.json
      /records/222/generic_name      		Historical; current review incomplete
      H51-A40B4482A1EF41BE563F5915dosing.json
      /records/222/coverage_status      		Historical; current review incomplete
      H51-376F64DEBC617682185CC74Edosing.json
      /records/222/package_insert/query_name      		Historical; current review incomplete
      H51-120D97EAF94C53073D48CB4Adosing.json
      /records/222/package_insert/preferred_setid      		Historical; current review incomplete
      H51-FEC87B034C31636C19511AAFdosing.json
      /records/222/package_insert/product_and_route_must_match      		Historical; current review incomplete
      H51-1F506CD43813C697ECDE96AAdosing.json
      /records/222/package_insert/live_current_label_enabled      		Historical; current review incomplete
      H51-84BC41679EC8BCDD861D8384dosing.json
      /records/222/package_insert/source_priority      		Historical; current review incomplete
      H51-42662EECA4B3FD2B4C69418Cdosing.json
      /records/222/package_insert/direct_official_label_access_enabled      		Historical; current review incomplete
      H51-D9CF12AB7DF830C7798CF5A6dosing.json
      /records/222/package_insert/outbound_server_request_required      		Historical; current review incomplete
      H51-F010F7144D0EF623B6628012dosing.json
      /records/222/package_insert/local_summary_status      		Historical; current review incomplete
      H51-13A49CF89AE075A0A3437D3Cdosing.json
      /records/222/renal/classification      		Historical; current review incomplete
      H51-94729FE2B9DDF945BEBB416Adosing.json
      /records/222/renal/summary      		Historical; current review incomplete
      H51-42930DADF1B8A58887F5BA8Edosing.json
      /records/222/renal/method_note      		Historical; current review incomplete
      H51-37A6524FEE72DA04A8C7C2ECdosing.json
      /records/222/existing_route_snapshots/0      		Historical; current review incomplete
      H51-A2E59232685C96639BF32D6Ddosing.json
      /records/222/existing_route_snapshots/0/route      		Historical; current review incomplete
      H51-2F2FE44CE5DB6F1A05668DC6dosing.json
      /records/222/existing_route_snapshots/0/population      		Historical; current review incomplete
      H51-29FB46709AC5496EC7C19EB4dosing.json
      /records/222/existing_route_snapshots/0/indication      		Historical; current review incomplete
      H51-DC5EA77389DE444F3D8E8A0Bdosing.json
      /records/222/existing_route_snapshots/0/dose      		Historical; current review incomplete
      H51-A7560249586F313FCDABD605dosing.json
      /records/222/existing_route_snapshots/0/interval      		Historical; current review incomplete
      H51-3B6E10E5A5307562CB9050FDdosing.json
      /records/222/existing_route_snapshots/0/duration      		Historical; current review incomplete
      H51-D67A9C7F29871C00595C9868dosing.json
      /records/222/existing_route_snapshots/0/administration      		Historical; current review incomplete
      H51-820680F754DC6A059FE11FD9dosing.json
      /records/222/existing_route_snapshots/0/source_level      		Historical; current review incomplete
      H51-DFB33E1BEFDC1BB47FF7C89Fdosing.json
      /records/222/existing_route_snapshots/0/notes      		Historical; current review incomplete
      H51-215521ED89413A1CAD70124Adosing.json
      /records/222/existing_route_snapshots/1      		Historical; current review incomplete
      H51-65AB28A9900316F26A1BF1B5dosing.json
      /records/222/existing_route_snapshots/1/route      		Historical; current review incomplete
      H51-6F6B17798FF641CC787D5BA2dosing.json
      /records/222/existing_route_snapshots/1/population      		Historical; current review incomplete
      H51-6B2A2B850D3B0318B5CCE16Ddosing.json
      /records/222/existing_route_snapshots/1/indication      		Historical; current review incomplete
      H51-C02E7648659B6210E19E21BAdosing.json
      /records/222/existing_route_snapshots/1/dose      		Historical; current review incomplete
      H51-EE017D8A2C5F9124CE321EAEdosing.json
      /records/222/existing_route_snapshots/1/interval      		Historical; current review incomplete
      H51-B0B5D8105492C63AFD7B07E0dosing.json
      /records/222/existing_route_snapshots/1/duration      		Historical; current review incomplete
      H51-42DDEF99F5D8376A6758A87Adosing.json
      /records/222/existing_route_snapshots/1/administration      		Historical; current review incomplete
      H51-D7D516F061313E586A49730Cdosing.json
      /records/222/existing_route_snapshots/1/source_level      		Historical; current review incomplete
      H51-D37F9EBB95FAF1DDBFC7CF84dosing.json
      /records/222/existing_route_snapshots/1/notes      		Historical; current review incomplete
      H51-70CD229D683961DF7A20673Cdosing.json
      /records/222/existing_route_snapshots/2      		Historical; current review incomplete
      H51-1B640B2603864546C8AC00F8dosing.json
      /records/222/existing_route_snapshots/2/route      		Historical; current review incomplete
      H51-06D577814909BADF28EBC40Bdosing.json
      /records/222/existing_route_snapshots/2/population      		Historical; current review incomplete
      H51-49E2525DFFCDAD0D7685398Fdosing.json
      /records/222/existing_route_snapshots/2/indication      		Historical; current review incomplete
      H51-71494BD0F0890F7530F05AD6dosing.json
      /records/222/existing_route_snapshots/2/dose      		Historical; current review incomplete
      H51-22C4AF3472852E014E7F353Bdosing.json
      /records/222/existing_route_snapshots/2/interval      		Historical; current review incomplete
      H51-841CF14C263C5159686303DBdosing.json
      /records/222/existing_route_snapshots/2/duration      		Historical; current review incomplete
      H51-E3268484BD7C5B823BAD399Ddosing.json
      /records/222/existing_route_snapshots/2/administration      		Historical; current review incomplete
      H51-A415E6B7998E66333E222A16dosing.json
      /records/222/existing_route_snapshots/2/source_level      		Historical; current review incomplete
      H51-3954AFE457A9D2C3A08378ABdosing.json
      /records/222/existing_route_snapshots/2/notes      		Historical; current review incomplete
      H51-FC1988448CE50378F24AC0AFdosing.json
      /records/222/existing_route_snapshots/3      		Historical; current review incomplete
      H51-53E26A153BB1CF2765E62904dosing.json
      /records/222/existing_route_snapshots/3/route      		Historical; current review incomplete
      H51-B61FD90740C6CCF4139FB399dosing.json
      /records/222/existing_route_snapshots/3/population      		Historical; current review incomplete
      H51-2C72BEE3FBA88AD5A7248A3Bdosing.json
      /records/222/existing_route_snapshots/3/indication      		Historical; current review incomplete
      H51-4036B2CCA37CE3379E81A29Fdosing.json
      /records/222/existing_route_snapshots/3/dose      		Historical; current review incomplete
      H51-0F0CE297507940A2F7E61090dosing.json
      /records/222/existing_route_snapshots/3/interval      		Historical; current review incomplete
      H51-9DC49B3766D45AAF07DD1207dosing.json
      /records/222/existing_route_snapshots/3/duration      		Historical; current review incomplete
      H51-3C5F292F31A1F19D686B5BC3dosing.json
      /records/222/existing_route_snapshots/3/administration      		Historical; current review incomplete
      H51-06EA9B1BE1660D7FE5B9F75Ddosing.json
      /records/222/existing_route_snapshots/3/source_level      		Historical; current review incomplete
      H51-46EA17651E9E155CAACC7656dosing.json
      /records/222/existing_route_snapshots/3/notes      		Historical; current review incomplete
      H51-DC22CA956F0838286CCCAD2Cdosing.json
      /records/222/clinical_review/locally_normalized      		Historical; current review incomplete
      H51-6C4905EA6B737F8C03CB1DD6dosing.json
      /records/222/clinical_review/reviewed      		Historical; current review incomplete
      H51-1E610C16A3A5B1C49D6420C9dosing.json
      /records/222/clinical_review/status      		Historical; current review incomplete
      H51-F713E3395821F03433ADB48Edosing.json
      /records/222/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-270C374070E8132FE2E2BF29dosing.json
      /records/222/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-8F53933848FF06184249BC1Cdosing.json
      /records/222/clinical_release_verification/level      		Historical; current review incomplete
      H51-98F528C9B2BBEFD89E68B1AEdosing.json
      /records/222/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-AF6DBD95D9CDC544E890425Cdosing.json
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      H51-F318ECD9F1CCE025E905FA26dosing.json
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      H51-60A02F162BFC6F1209EA8D26first-look-v5.1.json
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      /222/clinical_release_note      		Historical; current review incomplete
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