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IV Dilution & Medication Referencev7.4
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Regular insulin

Dilution requiredFull monograph review pending

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Historical dilution reference. Verify the preparation against the label for the product in hand.

Original GlobalRPh article: Insulin (regular) (opens in a new tab)Original source URL: https://globalrph.com/dilution/insulin-regular/ Retrieved 2026-11-04

Historical source details

Original publication date: unavailable in the retrieved article.

Source location and file checksums
Original source URL
https://globalrph.com/dilution/insulin-regular/ (opens in a new tab)
Source date
Not established in the retrieved source
Retrieved
2026-11-04T19:49:26.880780+00:00
Source location
div.post-content
Packaged content SHA-256
a2b5b069680ea4ba8cef5a2ccc0bf3ce90f3ebfa062ec5ac9414a73f6afa3579
Original response SHA-256
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Source body SHA-256
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Insulin (regular)

The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this document shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.

Usual Diluents

NS

Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]

Usual final concentrations:
0.5 unit/ml or 1 unit/ml

(ICU's only - Detroit VAMC)
[120 units/ 240 ml] [Titrate]
[100 units] [100 ml] [Titrate]

Stability / Miscellaneous

EXP: 1 DAY (RT/REF)

Open this historical article on its own

U.S. label preparation

Humulin R U-100 multiple-dose vial · Dilution required

Preparation
For an IV infusion, prepare regular human insulin at 0.1 to 1 unit/mL in an infusion system containing 0.9% sodium chloride. These instructions apply only to the U-100 vial.
Administration and handling
Administer under medical supervision with close monitoring of blood glucose and potassium. The sterile insulin diluent described for subcutaneous injection is for that route only.
Product and source details

Eli Lilly and Company · BLA018780

Product NDC: 0002-0213, 0002-8215

SPL effective 2026-06-16 | SPL version 35. Checked 2026-11-13.

Source for this summary: U.S. prescribing information. Use the full label for dose selection, contraindications, preparation tables and monitoring.

Product identifiers and clinical review status

U.S. label preparation available. Full monograph review pending.

Selected product identity

The selected product is identified for this preparation.

View product identifiers and primary-label provenance
Selected product scope
Humulin R U-100 multiple-dose vial
Labeler
Eli Lilly and Company
Application number(s)
BLA018780
NDC(s)
0002-0213; 0002-8215
DailyMed Set ID
b519bd83-038c-4ec5-a231-a51ec5cc291f
SPL version
35
Label printed revision date
Not established
SPL effective date
2026-06-16
Retrieved
2026-11-13
Downloaded XML SHA-256
725b535bcb3b23344295414cbad7c3eef306a46c9a6366b31b172ce3bd0eb397

Selected label Humulin R U-100 multiple-dose vial

What remains to be completed
  • Obtain independent corroboration of the label preparation where available.
  • Complete indication- and age-specific dosing, incompatibility, monitoring and stability review.
  • Assess any proposed compounding BUD for the exact formulation, concentration, container and conditions.