Skip to application
All calculators and tools

Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
Back to resultsA-Z list

Medication reference

Penicillin G

Monograph awaiting updateThis monograph will be updated in the future.

Jump to a section
Search DailyMed products (opens in a new tab)

Historical source. Current clinical review is incomplete. This monograph will be updated in the future.

Penicillin G (opens in a new tab)Original source URL: https://globalrph.com/dilution/penicillin-g/ | Retrieved 2026-11-04

Source dates, location and integrity

This historical article is separate from the reviewed claim cards. Product formulations and source dates may differ.

Original source URL
https://globalrph.com/dilution/penicillin-g/ (opens in a new tab)
Source date
Not established in the retrieved source
Retrieved
2026-11-04T19:47:02.058286+00:00
Source location
div.post-content
Packaged content SHA-256
e4f16d20bc7b9c6f7328ce26d24da172ffa140af11d36221f64dabb59986a1a9
Original response SHA-256
1d87c860860249360c6522416c22739607a019f548bb2b3b39ceb91733339987
Source body SHA-256
a861440de9dcb8179b9b47c3464bdc76494352a9932b3b6cdf26ba2f5c98bd5f

Penicillin G
The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this document shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.

Usual Diluents
D5W, NS

Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]
[0 to 4 MU] [50 ml] [30 min]*
*Sample infusion times:
-Lexi-comp (June 2013) Digital version: Intermittent I.V.: ... Infuse over 15-30 minutes.
-Micromedex (June 2013): The preferred intravenous route is by continuous infusion or intermittent piggyback injections over 30 to 60 minutes.
-AHFS DRUG INFORMATION® (2013) For intermittent IV infusion, penicillin G potassium or sodium should generally be infused over 1-2 hours..... Divided doses of the drug have also been infused intermittently IV over 15-30 minutes in neonates and children.


Stability / Miscellaneous
EXP: 1 DAY (RT) /7 DAYS (REF). Label: Refrigerate.

Stability data:
Drug Stability
Refrigerated		 Stability
Room Temp.		 Reconstituted
Vial/Powder		 Notes
Penicillin Powder Sterile constituted solution may be kept in refrigerator 2° to 8°C (36° to 46°F) for 7 days without significant loss of potency. Store the dry powder at 20° to 25°C (68° to 77°F) Powder

STORAGE:
Admixture: All solutions should be stored in a refrigerator at 2º to 8ºC (36º to 46ºF). When refrigerated, penicillin solutions may be stored for seven days without significant loss of potency. DISCARD UNUSED SOLUTION AFTER 7 DAYS.

Reconstituted vial: Sterile constituted solution may be kept in refrigerator (2° to 8°C) for 3 days without significant loss of potency. Vial: Store dry powder at 20°-25°C (68°-77°F) (see USP Controlled Room Temperature).

Usual dose: 0.5 to 4 mu q4-6h.
Severe infection: Dosing interval q2-3h (i.e. 3mu q3h).

DOSAGE AND ADMINISTRATION
Penicillin G Potassium Injection, USP should be administered by intravenous infusion. The usual dose recommendations are as follows:

Adult patients
*Because of its short half-life, Penicillin G is administered in divided doses,usually
every 4-6 hours with the exception of meningococcal meningitis/septicemia, i.e., every 2 hours.

CLINICAL INDICATION DOSAGE
Serious infections due to susceptible strains of streptococci (including S. pneumoniae)
-septicemia, empyema, pneumonia, pericarditis, endocarditis and meningitis		 12 to 24 million units/day depending on the infection and its severity administered in equally divided doses every 4-6 hours.

Serious infections due to susceptible strains of staphylococci
- septicemia, empyema, pneumonia, pericarditis, endocarditis and meningitis		 5 to 24 million units/day depending on the infection and its severity administered in equally divided doses every 4-6 hours.

Anthrax Minimum of 8 million units/day in divided doses every 6 hours. Higher doses may be required depending on susceptibility of organism.
Actinomycosis
Cervicofacial disease
Thoracic and abdominal disease		 1 to 6 million units/day(*)
10 to 20 million units/day(*)
Clostridial infections
Botulism (adjunctive therapy to antitoxin)
Gas gangrene (debridement and/or surgery as indicated)
Tetanus (adjunctive therapy to human tetanus immune globulin)		 20 million units/day(*)
Diphtheria (adjunctive therapy to antitoxin and for the prevention of the carrier state) 2 to 3 million units/day in divided doses for 10-12 days(*)
Erysipelothrix endocarditis 12 to 20 million units/day for 4-6 weeks(*)
Fusospirochetosis (severe infections of the oropharynx [Vincent’s], lower respiratory tract and genital area) 5 to 10 million units/day(*)
Listeria infections
Meningitis
Endocarditis		 15 to 20 million units/day for 2 weeks(*)
15 to 20 million units/day for 4 weeks(*)
Pasteurella infections including bacteremia and meningitis

4 to 6 million units/day for 2 weeks(*)
Haverhill fever; Rat-bite fever 12 to 20 million units/day for 3-4 weeks(*)

Disseminated gonococcal infections, such as meningitis endocarditis, arthritis, etc., caused by penicillin - susceptible organisms

10 million units/day(*); duration depends on the type of infection
Syphilis (neurosyphilis) 12 to 24 million units/day, as 2-4 MU every 4 hours for 10-14 days; many experts recommend additional therapy with Benzathine PCN G 2.4 MU IM weekly for 3 doses after completion of IV therapy

Meningococcal meningitis and/or septicemia 24 million units/day as 2 million units every 2 hours

Renal Impairment: Penicillin G is relatively nontoxic, and dosage adjustments are generally required only in cases of severe renal impairment. The recommended dosage regimens are as follows:

Separate renal reference: Open Renal Dosing Master (opens in a new tab)

Creatinine clearance less than 10 mL/min/1.73m2; administer a full loading dose (see recommended dosages in the tables above) followed by one-half of the loading dose every 8-10 hours.

Uremic patients with a creatinine clearance greater than 10 mL/min/1.73m2; administer a full loading dose (see recommended dosages in the tables above) followed by one-half of the loading dose every 4-5 hours. Additional dosage modifications should be made in patients with hepatic disease and renal impairment.

Source:
PENICILLIN G POTASSIUM FOR INJECTION (penicillin g potassium) powder, for solution
[APP Pharmaceuticals, LLC] Schaumburg, IL 60173. Revised: 09/2009.

Open this historical article on its own

Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • Retrievable exact-product SPL XML with version, revision, retrieval date and reproducible hash
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
adjustment_required
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        class_level
        Provenance classification
        historical_class_level
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.
      Historical first look: uses, mechanism, dosing context, and administration

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      penicillin-g
      Source IDH51-372929FA64B6E3A109F953B4
      Generic name
      Penicillin G
      Source IDH51-F6A677C3B7C43229C47C4E9F
      Class
      Antibacterial
      Source IDH51-7D7065545E4F03A2D8255808
      Subclass
      Legacy GlobalRPh directory entry
      Source IDH51-E8666DDAAE73E9C4F30395AB
      Primary uses
      1. Selected susceptible bacterial infections; indication, site, organism, local susceptibility, and current labeling determine use.
        Source IDH51-1C6102A6809563D8D85C4CD2
      Mechanism
      Beta-lactam binding to bacterial penicillin-binding proteins inhibits peptidoglycan cross-linking and cell-wall synthesis.
      Source IDH51-D0191C83E90A8D842B69892F
      Mechanism level
      class_level
      Source IDH51-65CF786FF7EFFC32F04B71EB
      Basic dosing orientation
      The existing GlobalRPh dose and preparation quick reference loads automatically below. Treat it as historical continuity, then confirm the exact current DailyMed label, population, indication, renal function, and institutional policy.
      Source IDH51-0DCF7B48666A5864E47CA101
      Administration orientation
      Route, dilution, concentration, and administration details load automatically from the existing GlobalRPh quick reference below; current exact-product verification remains required.
      Source IDH51-654463B337F5C94ED5AABB3D
      Renal and population orientation
      Separate renal reference: Open Renal Dosing Master (opens in a new tab)Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method.
      Source IDH51-5F1DC974165A97C65901B8A1
      Key safety orientation
      1. Legacy content must be reconciled against current labeling and institutional policy before clinical use.
        Source IDH51-F97263F54FF1402EC8985E01
      Coverage path
      automatic_legacy_quick_reference
      Source IDH51-031BD3FC78AD0BF373F32C79
      Coverage path label
      Automatic legacy GlobalRPh quick reference
      Source IDH51-3550C739BAAEC5965FFBA760
      Legacy title
      Penicillin G
      Source IDH51-D1E18F2906BF48D33C713FED
      Review note
      First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
      Source IDH51-5900C7AFD9672CD65AE4B193
      Search text
      Penicillin G Antibacterial Legacy GlobalRPh directory entry Selected susceptible bacterial infections; indication, site, organism, local susceptibility, and current labeling determine use. Beta-lactam binding to bacterial penicillin-binding proteins inhibits peptidoglycan cross-linking and cell-wall synthesis. The existing GlobalRPh dose and preparation quick reference loads automatically below. Treat it as historical continuity, then confirm the exact current DailyMed label, population, indication, renal function, and institutional policy. Route, dilution, concentration, and administration details load automatically from the existing GlobalRPh quick reference below; current exact-product verification remains required. Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method. Legacy content must be reconciled against current labeling and institutional policy before clinical use. Automatic legacy GlobalRPh quick reference
      Source IDH51-639AC7FA19779519DED9F0FB
      Official access mode
      search
      Source IDH51-153E7995C9855613AC6F66C2
      Official search query
      Penicillin G
      Source IDH51-15D9DA8EBEE8391881DC7E3A
      Official access reason
      A source-backed DailyMed search is available; select and confirm the exact IV product.
      Source IDH51-4137B8C31EE9962A173BB854

      No separate structured rows were bundled for preparation, IV push, continuous infusion, population dosing, dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      adjustment_required
      Source IDH51-0C1E7812FF1039783CCC5B30
      Summary
      Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method.
      Source IDH51-9860E4BB619A42B2A6B4BE72
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-FFBFB889245E3B8A38CCC508

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Legacy content must be reconciled against current labeling and institutional policy before clinical use.
        Source IDH51-2CEB2F5D8A56F9173BAF8042

      Historical Stability notes

      Recovered v5.1 source content; historical, awaiting current review.

      1. Legacy product stability information is not automatically equivalent to a USP <797> BUD.
        Source IDH51-605B3EC6D88ED8599DDF9D59

      Historical supplemental professional sources

      Recovered v5.1 source content; historical, awaiting current review.

      LabelUrlKind
      Source IDH51-0BD06716D6F1334C2886E5DB
      UCSF adult antimicrobial dosing, non-dialysis
      Source IDH51-0CD9BD9C38F197648919629E
      		https://idmp.ucsf.edu/adult-antimicrobial-dosing-non-dialysis (opens in a new tab)
      Source IDH51-6A8289E91989E26E51014E91
      		Professional institutional guidance
      Source IDH51-CAE6A1D1AF4A36592BB9277F
      Source IDH51-16624D0006AAF027A9C5B64A
      UCSF antimicrobial dosing in intermittent and continuous hemodialysis
      Source IDH51-5E48B4D094A3202489961272
      		https://idmp.ucsf.edu/antimicrobial-dosing-intermittent-continuous-hemodialysis (opens in a new tab)
      Source IDH51-0448FA066550B105FDF17C7A
      		Professional institutional guidance
      Source IDH51-A8B4F453C81DC0EF76F9E837
      Source IDH51-BAAA73CF13B3B59A2472D12B
      UCSF pediatric antimicrobial dosing
      Source IDH51-2611702A4E32CBF76A0054E8
      		https://idmp.ucsf.edu/pediatric-antimicrobial-dosing-benioff-childrens-hospitals (opens in a new tab)
      Source IDH51-1BDB98702932A6876D34974E
      		Professional institutional guidance
      Source IDH51-0A5B923CA123472AEBF3928D
      Source IDH51-481B57D511209CEB255961E9
      UCSF neonatal antimicrobial dosing
      Source IDH51-E10595C8E6E1FC3F8DE44055
      		https://idmp.ucsf.edu/neonatal-antimicrobial-dosing-benioff-childrens-hospitals (opens in a new tab)
      Source IDH51-BA34D3DA9B5A0CA22403212C
      		Professional institutional guidance
      Source IDH51-78B91DFEBEC84084A90DA309
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      penicillin-g
      Source IDH51-7A15E578D5BBD0DE6CC02450
      Legacy title
      Penicillin G
      Source IDH51-CB03C9AA1B9FED411F4D58C3
      Generic name
      Penicillin G
      Source IDH51-E990C20F3822DC93575E24BE
      Class
      Antibacterial
      Source IDH51-584F21FB06163144D9D9724A
      Subclass
      Legacy GlobalRPh directory entry
      Source IDH51-1A5E7ED928668A93192E09E7
      Summary
      Existing GlobalRPh IV dilution monograph retained for migration into the unified reference.
      Source IDH51-CDE5C5F5026843C7E32BFEEF
      Populations
      1. Population not yet normalized
        Source IDH51-D1DD92F5628BD2063A697B91
      Evidence tier
      Legacy catalog - migration review required
      Source IDH51-53C49D848B8009BCF046EC3F
      High alert
      false
      Source IDH51-571BAC45AA2162CFAE1880AD
      Hazardous
      false
      Source IDH51-80EF840FC531E5B0410B9992
      Status
      Legacy migration
      Source IDH51-5440546459A6FECAE6D7ADC6
      Version added
      Legacy
      Source IDH51-DE7370FEF883509DA8EF46E1
      Sources
      LabelUrlKind
      Source IDH51-D1B17D497FD1C7A57DDBEFEA
      GlobalRPh legacy IV dilution monograph
      Source IDH51-04AD8F5640931DAA670BDEBF
      		legacy:auto
      Source IDH51-A7C4CC2A68075D20D363A072
      		Legacy
      Source IDH51-6CFA93D945167BDFE3281B85
      Clinical release verification
      Audit version
      3.4
      Source IDH51-6F0E939FA34E928EF947A82E
      Audited on
      2026-08-30
      Source IDH51-4468ACEE399F95C4B6E0FB70
      Level
      amber
      Source IDH51-684EB4FA1BFC749B6655DE06
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-5AA7D12AD82F791033AE1E21
      Exact current label candidate
      false
      Source IDH51-313A6E848360F77FBDC4B4A3
      Reference url count
      4
      Source IDH51-2436CE84A6124F4446636A26
      Broken reference count
      0
      Source IDH51-FF7967315221F8EAD0640350
      Point of use confirmation required
      true
      Source IDH51-0BF7BCE116112E00BC3892AC
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-AF1262058FCE87EAE9882939

      Dosing source fields

      Id
      penicillin-g
      Source IDH51-7724C6A36D7762D203F12F6B
      Generic name
      Penicillin G
      Source IDH51-17547937CA9E00372C84C106
      Coverage status
      direct_official_label_access_plus_legacy_reference
      Source IDH51-508FF6DC6A48E6189C71D178
      Package insert
      Query name
      Penicillin G
      Source IDH51-B864D825D1BFC90484E1922A
      Product and route must match
      true
      Source IDH51-D25EB8CF2AAA0EF453D16FEE
      Live current label enabled
      false
      Source IDH51-88DA8FF6A2C815FFD9A3D3D9
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-A71DAA6D3F2D8D40BF78A91E
      Direct official label access enabled
      true
      Source IDH51-704238EAEF4CF05D78A9BC15
      Outbound server request required
      false
      Source IDH51-644C2EA0ABF609099C6830F0
      Local summary status
      not_bundled
      Source IDH51-A06F27F3043137F2A53A9C15
      Clinical review
      Locally normalized
      false
      Source IDH51-BFAEE6F4CD569ECE76DEDF1A
      Reviewed
      2026-08-29
      Source IDH51-514F19C2C72425192D7BA495
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-9F850D34614DEF0E29D98E74
      Clinical release verification
      Audit version
      3.4
      Source IDH51-0A59E9E6D5C4222FB066080F
      Audited on
      2026-08-30
      Source IDH51-E8D7BC2E3A2AA42D465C9565
      Level
      amber
      Source IDH51-3F6328ABDB0C8D05C705722D
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-51C8744ADCF9AA88017933DC
      Exact current label candidate
      false
      Source IDH51-750F4F1F3A533A20315FC2D8
      Reference url count
      4
      Source IDH51-C061EFEB2CAFA8AF2877E41C
      Broken reference count
      0
      Source IDH51-F034484FA5EC31FDAFF8B66D
      Point of use confirmation required
      true
      Source IDH51-1D94CB12F7187B1362F8F4CD
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-E4FC7317BB72122C1CE90154
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      penicillin-g
      Source IDH51-2DABEA06A35FEDC3E927F821
      Name
      Penicillin G
      Source IDH51-CFDD5006C0DCF7C304E0A5F2
      Therapeutic class
      Antibacterial
      Source IDH51-2774664DD3A511D4E6959C55
      Review version
      3.1
      Source IDH51-291E6FD71E2CE65A546CC980
      Review date
      2026-08-30
      Source IDH51-A01A70B5F2D4BF23CB737C00
      Release status
      no_released_dilution_current_label_review_required
      Source IDH51-EA5ED395C7CFFA7642333EBE
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-AC6F410F11D2E64FF459DE6A
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-80F6E80F5682B6E62AB30A06
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-30561F07B4391AA40B50BF11
      Reconstitution concentration
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-A342FD7BB1B2685A26760AA9
      Maximum or recommended final concentration
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-9F9CC7822AF3EF646D2D7B62
      Appropriate standardized containers
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-A1526395BB99EEEBEF7C265C
      Adult dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-396255CA00C051D6BF920B79
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-3E49A8B517446F6ABD04E0F1
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-C99C03793680DFEDDEE24210
      Infusion time
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-0FEC4594C7D551A7C77C1A50
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-4788CB7796F89BC3543B876F
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-42C706C5B93EAA8845FE290F
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-80028B9DF4C2B9028FB1C284
      Reconstitution concentration
      Primary
      not_found
      Source IDH51-43A0874EBE82FFE332BA4D12
      Maximum or recommended final concentration
      Primary
      not_found
      Source IDH51-D98C9E84A8327DA2A6151C37
      Appropriate standardized containers
      Primary
      not_found
      Source IDH51-89950D2191D506B6642F8842
      Adult dosing range
      Primary
      not_found
      Source IDH51-FE323850A8F24D8767C4961F
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-4DBC9F4B0FF70F11B4DCB7E9
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-03336784CD5F49C5421A9F2B
      Infusion time
      Primary
      not_found
      Source IDH51-81F3701FE954AA595F1743F9
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-799732036E354413071A5A41
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-DF2BD6628863C68E31C04DE7
      Population applicability
      Adult
      Applicability
      not_established
      Source IDH51-6FED9FFBD770B2502FC5E10D
      Guide generation allowed
      false
      Source IDH51-CE347333D1EFC81F27761C3D
      Pediatric
      Applicability
      supported_or_source_present
      Source IDH51-8EB1E2B0E48A30F178EDDA81
      Guide generation allowed
      false
      Source IDH51-9F5BEA014926FBF3D0D2AF2B
      Neonatal
      Applicability
      supported_or_source_present
      Source IDH51-71C0DDE4C1EA629B5D6872B7
      Guide generation allowed
      false
      Source IDH51-AE3C2DCD9D71A3A8B8D83566
      Route presence
      Structured dilution
      false
      Source IDH51-3C7E485928BD1E0E1BB4851D
      Iv push
      false
      Source IDH51-EFC306E40D6D8B2E1730B633
      Continuous infusion
      false
      Source IDH51-B070E411B33387882C2C1A2F
      Pediatric source
      true
      Source IDH51-28D4B62676050AA1061DEFE5
      Neonatal source
      true
      Source IDH51-9FB120722682EFF79E636186
      Legacy reference
      Status
      not_available
      Source IDH51-8135F3A320E3AB5C867990F0
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-93F532B122A7FC4A6E91374F
      Source files
      1. catalog.json
        Source IDH51-E6814C381ED3FDD29DE46F3F
      2. dosing.json
        Source IDH51-E280F4022ADDCCACBA1EE9B8
      3. legacy-map.json
        Source IDH51-CE0637E824964224442DF2DE
      4. review-queue.json
        Source IDH51-423C6A64D594DFED0670DAC2
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-869851BF3B46CE0209AC8CBF
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-7A15E578D5BBD0DE6CC02450catalog.json
      /records/191/id      		Historical; current review incomplete
      H51-CB03C9AA1B9FED411F4D58C3catalog.json
      /records/191/legacy_title      		Historical; current review incomplete
      H51-E990C20F3822DC93575E24BEcatalog.json
      /records/191/generic_name      		Historical; current review incomplete
      H51-584F21FB06163144D9D9724Acatalog.json
      /records/191/class      		Historical; current review incomplete
      H51-1A5E7ED928668A93192E09E7catalog.json
      /records/191/subclass      		Historical; current review incomplete
      H51-CDE5C5F5026843C7E32BFEEFcatalog.json
      /records/191/summary      		Historical; current review incomplete
      H51-2CEB2F5D8A56F9173BAF8042catalog.json
      /records/191/warnings/0      		Historical; current review incomplete
      H51-605B3EC6D88ED8599DDF9D59catalog.json
      /records/191/stability_notes/0      		Historical; current review incomplete
      H51-D1DD92F5628BD2063A697B91catalog.json
      /records/191/populations/0      		Historical; current review incomplete
      H51-53C49D848B8009BCF046EC3Fcatalog.json
      /records/191/evidence_tier      		Historical; current review incomplete
      H51-571BAC45AA2162CFAE1880ADcatalog.json
      /records/191/high_alert      		Historical; current review incomplete
      H51-80EF840FC531E5B0410B9992catalog.json
      /records/191/hazardous      		Historical; current review incomplete
      H51-5440546459A6FECAE6D7ADC6catalog.json
      /records/191/status      		Historical; current review incomplete
      H51-4FCD182E03806DC3A5BC50E8catalog.json
      /records/191/reviewed      		Historical; current review incomplete
      H51-DE7370FEF883509DA8EF46E1catalog.json
      /records/191/version_added      		Historical; current review incomplete
      H51-D1B17D497FD1C7A57DDBEFEAcatalog.json
      /records/191/sources/0      		Historical; current review incomplete
      H51-04AD8F5640931DAA670BDEBFcatalog.json
      /records/191/sources/0/label      		Historical; current review incomplete
      H51-A7C4CC2A68075D20D363A072catalog.json
      /records/191/sources/0/url      		Historical; current review incomplete
      H51-6CFA93D945167BDFE3281B85catalog.json
      /records/191/sources/0/kind      		Historical; current review incomplete
      H51-6F0E939FA34E928EF947A82Ecatalog.json
      /records/191/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-4468ACEE399F95C4B6E0FB70catalog.json
      /records/191/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-684EB4FA1BFC749B6655DE06catalog.json
      /records/191/clinical_release_verification/level      		Historical; current review incomplete
      H51-5AA7D12AD82F791033AE1E21catalog.json
      /records/191/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-313A6E848360F77FBDC4B4A3catalog.json
      /records/191/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-CF2AEEF532984E36981F914Fcatalog.json
      /records/191/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-B1C13BCD0D49C79C2D2410D7catalog.json
      /records/191/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-90B98BA29F8947E966AF9D76catalog.json
      /records/191/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-2436CE84A6124F4446636A26catalog.json
      /records/191/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-FF7967315221F8EAD0640350catalog.json
      /records/191/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-0BF7BCE116112E00BC3892ACcatalog.json
      /records/191/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-AF1262058FCE87EAE9882939catalog.json
      /records/191/clinical_release_verification/note      		Historical; current review incomplete
      H51-435C1714F1EB1C4367DC4A0Fcatalog.json
      /records/191/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-7724C6A36D7762D203F12F6Bdosing.json
      /records/191/id      		Historical; current review incomplete
      H51-17547937CA9E00372C84C106dosing.json
      /records/191/generic_name      		Historical; current review incomplete
      H51-508FF6DC6A48E6189C71D178dosing.json
      /records/191/coverage_status      		Historical; current review incomplete
      H51-B864D825D1BFC90484E1922Adosing.json
      /records/191/package_insert/query_name      		Historical; current review incomplete
      H51-14069CD3821746848AEBF5DEdosing.json
      /records/191/package_insert/preferred_setid      		Historical; current review incomplete
      H51-D25EB8CF2AAA0EF453D16FEEdosing.json
      /records/191/package_insert/product_and_route_must_match      		Historical; current review incomplete
      H51-88DA8FF6A2C815FFD9A3D3D9dosing.json
      /records/191/package_insert/live_current_label_enabled      		Historical; current review incomplete
      H51-A71DAA6D3F2D8D40BF78A91Edosing.json
      /records/191/package_insert/source_priority      		Historical; current review incomplete
      H51-704238EAEF4CF05D78A9BC15dosing.json
      /records/191/package_insert/direct_official_label_access_enabled      		Historical; current review incomplete
      H51-644C2EA0ABF609099C6830F0dosing.json
      /records/191/package_insert/outbound_server_request_required      		Historical; current review incomplete
      H51-A06F27F3043137F2A53A9C15dosing.json
      /records/191/package_insert/local_summary_status      		Historical; current review incomplete
      H51-0C1E7812FF1039783CCC5B30dosing.json
      /records/191/renal/classification      		Historical; current review incomplete
      H51-9860E4BB619A42B2A6B4BE72dosing.json
      /records/191/renal/summary      		Historical; current review incomplete
      H51-FFBFB889245E3B8A38CCC508dosing.json
      /records/191/renal/method_note      		Historical; current review incomplete
      H51-0BD06716D6F1334C2886E5DBdosing.json
      /records/191/professional_sources/0      		Historical; current review incomplete
      H51-0CD9BD9C38F197648919629Edosing.json
      /records/191/professional_sources/0/label      		Historical; current review incomplete
      H51-6A8289E91989E26E51014E91dosing.json
      /records/191/professional_sources/0/url      		Historical; current review incomplete
      H51-CAE6A1D1AF4A36592BB9277Fdosing.json
      /records/191/professional_sources/0/kind      		Historical; current review incomplete
      H51-16624D0006AAF027A9C5B64Adosing.json
      /records/191/professional_sources/1      		Historical; current review incomplete
      H51-5E48B4D094A3202489961272dosing.json
      /records/191/professional_sources/1/label      		Historical; current review incomplete
      H51-0448FA066550B105FDF17C7Adosing.json
      /records/191/professional_sources/1/url      		Historical; current review incomplete
      H51-A8B4F453C81DC0EF76F9E837dosing.json
      /records/191/professional_sources/1/kind      		Historical; current review incomplete
      H51-BAAA73CF13B3B59A2472D12Bdosing.json
      /records/191/professional_sources/2      		Historical; current review incomplete
      H51-2611702A4E32CBF76A0054E8dosing.json
      /records/191/professional_sources/2/label      		Historical; current review incomplete
      H51-1BDB98702932A6876D34974Edosing.json
      /records/191/professional_sources/2/url      		Historical; current review incomplete
      H51-0A5B923CA123472AEBF3928Ddosing.json
      /records/191/professional_sources/2/kind      		Historical; current review incomplete
      H51-481B57D511209CEB255961E9dosing.json
      /records/191/professional_sources/3      		Historical; current review incomplete
      H51-E10595C8E6E1FC3F8DE44055dosing.json
      /records/191/professional_sources/3/label      		Historical; current review incomplete
      H51-BA34D3DA9B5A0CA22403212Cdosing.json
      /records/191/professional_sources/3/url      		Historical; current review incomplete
      H51-78B91DFEBEC84084A90DA309dosing.json
      /records/191/professional_sources/3/kind      		Historical; current review incomplete
      H51-BFAEE6F4CD569ECE76DEDF1Adosing.json
      /records/191/clinical_review/locally_normalized      		Historical; current review incomplete
      H51-514F19C2C72425192D7BA495dosing.json
      /records/191/clinical_review/reviewed      		Historical; current review incomplete
      H51-9F850D34614DEF0E29D98E74dosing.json
      /records/191/clinical_review/status      		Historical; current review incomplete
      H51-0A59E9E6D5C4222FB066080Fdosing.json
      /records/191/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-E8D7BC2E3A2AA42D465C9565dosing.json
      /records/191/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-3F6328ABDB0C8D05C705722Ddosing.json
      /records/191/clinical_release_verification/level      		Historical; current review incomplete
      H51-51C8744ADCF9AA88017933DCdosing.json
      /records/191/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-750F4F1F3A533A20315FC2D8dosing.json
      /records/191/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-59C4B88770C90000D369EC91dosing.json
      /records/191/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-00E926EEE44296A2E641F294dosing.json
      /records/191/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-3BD7F083103BD4C6E51CF55Ddosing.json
      /records/191/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-C061EFEB2CAFA8AF2877E41Cdosing.json
      /records/191/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-F034484FA5EC31FDAFF8B66Ddosing.json
      /records/191/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-1D94CB12F7187B1362F8F4CDdosing.json
      /records/191/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-E4FC7317BB72122C1CE90154dosing.json
      /records/191/clinical_release_verification/note      		Historical; current review incomplete
      H51-5E51685666E0E52F3A03A7D1dosing.json
      /records/191/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-372929FA64B6E3A109F953B4first-look-v5.1.json
      /records/191/id      		Historical; current review incomplete
      H51-F6A677C3B7C43229C47C4E9Ffirst-look-v5.1.json
      /records/191/generic_name      		Historical; current review incomplete
      H51-7D7065545E4F03A2D8255808first-look-v5.1.json
      /records/191/class      		Historical; current review incomplete
      H51-E8666DDAAE73E9C4F30395ABfirst-look-v5.1.json
      /records/191/subclass      		Historical; current review incomplete
      H51-1C6102A6809563D8D85C4CD2first-look-v5.1.json
      /records/191/primary_uses/0      		Historical; current review incomplete
      H51-D0191C83E90A8D842B69892Ffirst-look-v5.1.json
      /records/191/mechanism      		Historical; current review incomplete
      H51-65CF786FF7EFFC32F04B71EBfirst-look-v5.1.json
      /records/191/mechanism_level      		Historical; current review incomplete
      H51-0DCF7B48666A5864E47CA101first-look-v5.1.json
      /records/191/basic_dosing_orientation      		Historical; current review incomplete
      H51-654463B337F5C94ED5AABB3Dfirst-look-v5.1.json
      /records/191/administration_orientation      		Historical; current review incomplete
      H51-5F1DC974165A97C65901B8A1first-look-v5.1.json
      /records/191/renal_and_population_orientation      		Historical; current review incomplete
      H51-F97263F54FF1402EC8985E01first-look-v5.1.json
      /records/191/key_safety_orientation/0      		Historical; current review incomplete
      H51-031BD3FC78AD0BF373F32C79first-look-v5.1.json
      /records/191/coverage_path      		Historical; current review incomplete
      H51-3550C739BAAEC5965FFBA760first-look-v5.1.json
      /records/191/coverage_path_label      		Historical; current review incomplete
      H51-F7081B28DF688BACAD40624Efirst-look-v5.1.json
      /records/191/official_label_url      		Historical; current review incomplete
      H51-D1E18F2906BF48D33C713FEDfirst-look-v5.1.json
      /records/191/legacy_title      		Historical; current review incomplete
      H51-5900C7AFD9672CD65AE4B193first-look-v5.1.json
      /records/191/review_note      		Historical; current review incomplete
      H51-639AC7FA19779519DED9F0FBfirst-look-v5.1.json
      /records/191/search_text      		Historical; current review incomplete
      H51-D3E49D8985E1E940D3E48573first-look-v5.1.json
      /records/191/official_search_url      		Historical; current review incomplete
      H51-153E7995C9855613AC6F66C2first-look-v5.1.json
      /records/191/official_access_mode      		Historical; current review incomplete
      H51-F7BA23E45C5F4C73EC8EA998first-look-v5.1.json
      /records/191/official_access_url      		Historical; current review incomplete
      H51-15D9DA8EBEE8391881DC7E3Afirst-look-v5.1.json
      /records/191/official_search_query      		Historical; current review incomplete
      H51-4137B8C31EE9962A173BB854first-look-v5.1.json
      /records/191/official_access_reason      		Historical; current review incomplete
      H51-2DABEA06A35FEDC3E927F821preparation-assessments-v3.8.json
      /191/id      		Historical; current review incomplete
      H51-CFDD5006C0DCF7C304E0A5F2preparation-assessments-v3.8.json
      /191/name      		Historical; current review incomplete
      H51-0194813B37146846273FF8DDpreparation-assessments-v3.8.json
      /191/brands      		Historical; current review incomplete
      H51-2774664DD3A511D4E6959C55preparation-assessments-v3.8.json
      /191/therapeutic_class      		Historical; current review incomplete
      H51-291E6FD71E2CE65A546CC980preparation-assessments-v3.8.json
      /191/review_version      		Historical; current review incomplete
      H51-A01A70B5F2D4BF23CB737C00preparation-assessments-v3.8.json
      /191/review_date      		Historical; current review incomplete
      H51-EA5ED395C7CFFA7642333EBEpreparation-assessments-v3.8.json
      /191/release_status      		Historical; current review incomplete
      H51-AC6F410F11D2E64FF459DE6Apreparation-assessments-v3.8.json
      /191/market_status/status      		Historical; current review incomplete
      H51-80F6E80F5682B6E62AB30A06preparation-assessments-v3.8.json
      /191/market_status/basis      		Historical; current review incomplete
      H51-30561F07B4391AA40B50BF11preparation-assessments-v3.8.json
      /191/ten_point_assessment/exact_formulation      		Historical; current review incomplete
      H51-A342FD7BB1B2685A26760AA9preparation-assessments-v3.8.json
      /191/ten_point_assessment/reconstitution_concentration      		Historical; current review incomplete
      H51-9F9CC7822AF3EF646D2D7B62preparation-assessments-v3.8.json
      /191/ten_point_assessment/maximum_or_recommended_final_concentration      		Historical; current review incomplete
      H51-A1526395BB99EEEBEF7C265Cpreparation-assessments-v3.8.json
      /191/ten_point_assessment/appropriate_standardized_containers      		Historical; current review incomplete
      H51-396255CA00C051D6BF920B79preparation-assessments-v3.8.json
      /191/ten_point_assessment/adult_dosing_range      		Historical; current review incomplete
      H51-3E49A8B517446F6ABD04E0F1preparation-assessments-v3.8.json
      /191/ten_point_assessment/pediatric_dosing_range      		Historical; current review incomplete
      H51-C99C03793680DFEDDEE24210preparation-assessments-v3.8.json
      /191/ten_point_assessment/neonatal_dosing_range      		Historical; current review incomplete
      H51-0FEC4594C7D551A7C77C1A50preparation-assessments-v3.8.json
      /191/ten_point_assessment/infusion_time      		Historical; current review incomplete
      H51-4788CB7796F89BC3543B876Fpreparation-assessments-v3.8.json
      /191/ten_point_assessment/fluid_restriction_alternatives      		Historical; current review incomplete
      H51-AF5C02E7574EE9E48A0D0493preparation-assessments-v3.8.json
      /191/ten_point_assessment/current_manufacturer_labeling/setid      		Historical; current review incomplete
      H51-8C684479EC1C0A01781B6CEEpreparation-assessments-v3.8.json
      /191/ten_point_assessment/current_manufacturer_labeling/title      		Historical; current review incomplete
      H51-8AD85F064A8BB870A5F2F981preparation-assessments-v3.8.json
      /191/ten_point_assessment/current_manufacturer_labeling/published_date      		Historical; current review incomplete
      H51-27BCBB609B85476CCC416378preparation-assessments-v3.8.json
      /191/ten_point_assessment/current_manufacturer_labeling/manufacturer      		Historical; current review incomplete
      H51-42C706C5B93EAA8845FE290Fpreparation-assessments-v3.8.json
      /191/ten_point_assessment/current_manufacturer_labeling/match_confidence      		Historical; current review incomplete
      H51-E40437674385CB6D9C635853preparation-assessments-v3.8.json
      /191/ten_point_assessment/current_manufacturer_labeling/url      		Historical; current review incomplete
      H51-80028B9DF4C2B9028FB1C284preparation-assessments-v3.8.json
      /191/field_provenance/exact_formulation/primary      		Historical; current review incomplete
      H51-43A0874EBE82FFE332BA4D12preparation-assessments-v3.8.json
      /191/field_provenance/reconstitution_concentration/primary      		Historical; current review incomplete
      H51-D98C9E84A8327DA2A6151C37preparation-assessments-v3.8.json
      /191/field_provenance/maximum_or_recommended_final_concentration/primary      		Historical; current review incomplete
      H51-89950D2191D506B6642F8842preparation-assessments-v3.8.json
      /191/field_provenance/appropriate_standardized_containers/primary      		Historical; current review incomplete
      H51-FE323850A8F24D8767C4961Fpreparation-assessments-v3.8.json
      /191/field_provenance/adult_dosing_range/primary      		Historical; current review incomplete
      H51-4DBC9F4B0FF70F11B4DCB7E9preparation-assessments-v3.8.json
      /191/field_provenance/pediatric_dosing_range/primary      		Historical; current review incomplete
      H51-03336784CD5F49C5421A9F2Bpreparation-assessments-v3.8.json
      /191/field_provenance/neonatal_dosing_range/primary      		Historical; current review incomplete
      H51-81F3701FE954AA595F1743F9preparation-assessments-v3.8.json
      /191/field_provenance/infusion_time/primary      		Historical; current review incomplete
      H51-799732036E354413071A5A41preparation-assessments-v3.8.json
      /191/field_provenance/fluid_restriction_alternatives/primary      		Historical; current review incomplete
      H51-DF2BD6628863C68E31C04DE7preparation-assessments-v3.8.json
      /191/field_provenance/current_manufacturer_labeling/primary      		Historical; current review incomplete
      H51-6FED9FFBD770B2502FC5E10Dpreparation-assessments-v3.8.json
      /191/population_applicability/adult/applicability      		Historical; current review incomplete
      H51-CE347333D1EFC81F27761C3Dpreparation-assessments-v3.8.json
      /191/population_applicability/adult/guide_generation_allowed      		Historical; current review incomplete
      H51-8EB1E2B0E48A30F178EDDA81preparation-assessments-v3.8.json
      /191/population_applicability/pediatric/applicability      		Historical; current review incomplete
      H51-9F5BEA014926FBF3D0D2AF2Bpreparation-assessments-v3.8.json
      /191/population_applicability/pediatric/guide_generation_allowed      		Historical; current review incomplete
      H51-71C0DDE4C1EA629B5D6872B7preparation-assessments-v3.8.json
      /191/population_applicability/neonatal/applicability      		Historical; current review incomplete
      H51-AE3C2DCD9D71A3A8B8D83566preparation-assessments-v3.8.json
      /191/population_applicability/neonatal/guide_generation_allowed      		Historical; current review incomplete
      H51-3C7E485928BD1E0E1BB4851Dpreparation-assessments-v3.8.json
      /191/route_presence/structured_dilution      		Historical; current review incomplete
      H51-EFC306E40D6D8B2E1730B633preparation-assessments-v3.8.json
      /191/route_presence/iv_push      		Historical; current review incomplete
      H51-B070E411B33387882C2C1A2Fpreparation-assessments-v3.8.json
      /191/route_presence/continuous_infusion      		Historical; current review incomplete
      H51-28D4B62676050AA1061DEFE5preparation-assessments-v3.8.json
      /191/route_presence/pediatric_source      		Historical; current review incomplete
      H51-9FB120722682EFF79E636186preparation-assessments-v3.8.json
      /191/route_presence/neonatal_source      		Historical; current review incomplete
      H51-8135F3A320E3AB5C867990F0preparation-assessments-v3.8.json
      /191/legacy_reference/status      		Historical; current review incomplete
      H51-93F532B122A7FC4A6E91374Fpreparation-assessments-v3.8.json
      /191/label_resolution/status      		Historical; current review incomplete
      H51-E6814C381ED3FDD29DE46F3Fpreparation-assessments-v3.8.json
      /191/source_files/0      		Historical; current review incomplete
      H51-E280F4022ADDCCACBA1EE9B8preparation-assessments-v3.8.json
      /191/source_files/1      		Historical; current review incomplete
      H51-CE0637E824964224442DF2DEpreparation-assessments-v3.8.json
      /191/source_files/2      		Historical; current review incomplete
      H51-423C6A64D594DFED0670DAC2preparation-assessments-v3.8.json
      /191/source_files/3      		Historical; current review incomplete
      H51-869851BF3B46CE0209AC8CBFpreparation-assessments-v3.8.json
      /191/clinical_release_note      		Historical; current review incomplete

      Open the original GlobalRPh site monograph (historical; not revalidated) (opens in a new tab)

      All medicationsReturn to medication headingApplication top