Natalizumab-sztn (Tyruko)
Dilution requiredFull monograph review pending
U.S. label preparation
Tyruko · Dilution required
- Preparation
- Add 15 mL (300 mg) to 100 mL of 0.9% sodium chloride. Use only this diluent, then gently invert the bag.
- Administration and handling
- Infuse over approximately 1 hour. Flush with 0.9% sodium chloride and follow the label for hypersensitivity observation.
Product and source details
Sandoz Inc · BLA761322
Product NDC: 61314-543
SPL effective 2025-10-31 | SPL version 13. Checked 2026-11-13.
Source for this summary: U.S. prescribing information. Use the full label for dose selection, contraindications, preparation tables and monitoring.
Product identifiers and clinical review status
U.S. label preparation available. Full monograph review pending.
Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.
What remains to be completed
- Obtain independent corroboration of the label preparation where available.
- Complete indication- and age-specific dosing, incompatibility, monitoring and stability review.
- Assess any proposed compounding BUD for the exact formulation, concentration, container and conditions.