Methylene blue
Optional dilutionFull monograph review pending
U.S. label preparation
ProvayBlue · Optional dilution
- Preparation
- For the 5 mg/mL ProvayBlue IV formulation, the label permits dilution in 50 mL of 5% dextrose to reduce local pain. Avoid sodium chloride solutions because chloride reduces methylene blue solubility.
- Administration and handling
- Use the diluted solution immediately. Verify the product strength, indication, contraindications and boxed warning before administration.
Product and source details
American Regent, Inc. · NDA204630
Product NDC: 0517-0374, 0517-0381, 0517-0125, 0517-0371
SPL effective 2025-05-28 | SPL version 28. Checked 2026-11-13.
Source for this summary: U.S. prescribing information. Use the full label for dose selection, contraindications, preparation tables and monitoring.
Product identifiers and clinical review status
U.S. label preparation available. Full monograph review pending.
Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.
What remains to be completed
- Obtain independent corroboration of the label preparation where available.
- Complete indication- and age-specific dosing, incompatibility, monitoring and stability review.
- Assess any proposed compounding BUD for the exact formulation, concentration, container and conditions.