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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Medication reference

Meropenem-vaborbactam

Monograph awaiting updateThis monograph will be updated in the future.

Jump to a section
Selected DailyMed label (opens in a new tab)

No original site article was mapped to this record. The available historical structured fields and official-source links are retained.

Historical first look: uses, mechanism, dosing context, and administration

Recovered v5.1 source content; historical, awaiting current review.

Id
meropenem-vaborbactam
Source IDH51-585E09797EEFCAD7E29A7D3B
Generic name
Meropenem-vaborbactam
Source IDH51-2B8E105B88A1E56D1CBCA788
Class
Antibacterial
Source IDH51-16553D7D156CC652E456EADE
Subclass
Carbapenem plus beta-lactamase inhibitor
Source IDH51-FC45CA4519F0E54452098790
Primary uses
  1. Complicated urinary infection including pyelonephritis in adults
    Source IDH51-273A660824C69C3E6281CD41
Mechanism
The beta-lactam component inhibits penicillin-binding proteins and cell-wall synthesis; its partner protects or enhances activity against selected resistance mechanisms.
Source IDH51-B3A0BF6F1CAFFB0DE52F2CFA
Mechanism level
class_level
Source IDH51-630CC988B34A840AC5FE765E
Basic dosing orientation
Adult, normal renal function | Existing preparation record; use current package insert for indication-specific selection | 4 g total (2 g meropenem/2 g vaborbactam) every 8 hours | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion
Source IDH51-930555D808508F3BEF5EB5B0
Administration orientation
Infuse over 3 hours
Source IDH51-D9DAE57BCAB57D6CBBE99EED
Renal and population orientation
Separate renal reference: Open Renal Dosing Master (opens in a new tab)Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method.
Source IDH51-A65A63028F9DC815169FD245
Key safety orientation
  1. Seizure risk and valproate interaction from meropenem component.
    Source IDH51-BBA14C7195CC1F62868889E8
  2. Serious beta-lactam hypersensitivity.
    Source IDH51-8650FC239423BC53BF4EBAAE
Coverage path
structured_local_snapshot
Source IDH51-6A0E72F519D88B0A93BC8232
Coverage path label
Structured GlobalRPh route snapshot
Source IDH51-AED3D6354B7287595222D56E
Review note
First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
Source IDH51-26E4FDDBF5B391E4C54962A9
Search text
Meropenem-vaborbactam Antibacterial Carbapenem plus beta-lactamase inhibitor Complicated urinary infection including pyelonephritis in adults The beta-lactam component inhibits penicillin-binding proteins and cell-wall synthesis; its partner protects or enhances activity against selected resistance mechanisms. Adult, normal renal function | Existing preparation record; use current package insert for indication-specific selection | 4 g total (2 g meropenem/2 g vaborbactam) every 8 hours | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion Infuse over 3 hours Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method. Seizure risk and valproate interaction from meropenem component. Serious beta-lactam hypersensitivity. Structured GlobalRPh route snapshot VABOMERE VABOMERE (meropenem and vaborbactam) injection, powder, for solution DailyMed label snapshot dosage administration dosage forms strengths mechanism
Source IDH51-AC25412E9466C0A2987B4113
Official access mode
direct_label
Source IDH51-415DEF9F8F0963859EA93511
Official search query
Meropenem-vaborbactam
Source IDH51-73778BF23E330DC5581878AE
Official access reason
Very-high-confidence exact IV product label selected during the v5.1 build-time review. Open the current full DailyMed monograph and verify the stocked product before use.
Source IDH51-ED82BA02F0EBAA35F320301D
Label snapshot available
true
Source IDH51-8D77375596F2787A559C13E0
Label snapshot setid
e237fd0f-3050-42a3-b43e-b6fb4824e93d
Source IDH51-D2A2EE8C7B93F88C4C870189
Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • A retrieved source document is available; clinical reconciliation and a second-source claim map remain incomplete
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
adjustment_required
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        class_level
        Provenance classification
        historical_class_level
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      • Source kind
        label_snapshot
        Local pointer
        /mechanism_summary
        Original level
        class_level
        Provenance classification
        historical_class_level
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Concise GlobalRPh summary reviewed against the selected DailyMed label clinical-pharmacology or microbiology content.
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.

      No separate structured rows were bundled for IV push, continuous infusion, dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical dilution and intermittent infusion preparation

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      PopulationAmountReconstitutionDiluentFinal volumeConcentrationRateStabilityNotes
      Source IDH51-DFE5E0808037D7B731537686
      Adult, normal renal function
      Source IDH51-90F9FC84382EFDAEC7525834
      		4 g total (2 g meropenem/2 g vaborbactam) every 8 hours
      Source IDH51-3B2461AD9EF6818E4A2D4504
      		Reconstitute two vials as directed by current labeling and combine the required contents.
      Source IDH51-D0D8A0184C4AC07945A9B926
      		NS
      Source IDH51-3635137A87D80D68C00AC65B
      		250 mL commonly
      Source IDH51-59C7A41140B7D7449649E856
      		16 mg/mL total product when 4 g in 250 mL
      Source IDH51-EF78D8A9FA7E8FB08EC2A98A
      		Infuse over 3 hours
      Source IDH51-1334C5952A9A63EE7DB34771
      		Use the shorter of current product labeling, validated stability data, and the applicable USP <797> sterility-based BUD ceiling.
      Source IDH51-5D28A0822EEB7FFC887B49C6
      		Renal adjustment is required and dosing is timed from the start of infusion.
      Source IDH51-2A5BFF22F14036BA66A332CE

      Historical DailyMed label snapshot

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      meropenem-vaborbactam
      Source IDH51-DB88D53056ABFB51E9CE2581
      Catalog name
      Meropenem-vaborbactam
      Source IDH51-3F09E95C6BD5CDF13CB1C1F0
      Selection status
      accepted_high_confidence
      Source IDH51-30F18BFA9CCED932837C02EA
      Confidence
      very_high
      Source IDH51-41ED9EFC02F2460A41BF0299
      Match path
      search_to_exact_label
      Source IDH51-F0FA46444A2A96D4DA0D6E94
      Brand name
      VABOMERE
      Source IDH51-BB9A8D1F597CF599998E4DE0
      Label title
      VABOMERE (meropenem and vaborbactam) injection, powder, for solution
      Source IDH51-DE4B39613661675BBA6762C0
      Setid
      e237fd0f-3050-42a3-b43e-b6fb4824e93d
      Source IDH51-64BC7D88896ADF2C88D486B0
      Route
      Extended intravenous infusion
      Source IDH51-A47692571346CE761C8230D9
      Dosage form
      Combination powder for reconstitution and dilution
      Source IDH51-2DCFE6F8E15F0D438E404EBF
      Dosage administration summary
      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      1. For adults with estimated glomerular filtration rate at or above 50 mL/min/1.73 m2, administer 4 g every 8 hours over 3 hours.
        Source IDH51-97B18E590B87AD065D5C2DEE
      2. A full 4 g dose requires two single-dose vials; reconstitute and further dilute according to the current label.
        Source IDH51-EE1D2CABC0910CF8EFBABA88
      3. Renal function determines the dose and interval. Reassess renal function regularly and follow the hemodialysis timing instructions.
        Source IDH51-2FBF8029133F23D2B5CBBC50
      Dosage forms strengths
      1. Each vial contains 1 g meropenem and 1 g vaborbactam; two vials provide a 4 g dose
        Source IDH51-AAAAF34E669A30143BE09973
      Mechanism summary
      Meropenem inhibits bacterial cell-wall synthesis; vaborbactam inhibits selected serine beta-lactamases and protects meropenem from hydrolysis.
      Source IDH51-F5A36F74C5BFBA3D03B7B2E0
      Scope note
      Selected VABOMERE combination label. Do not apply this summary to meropenem alone.
      Source IDH51-A1F67F6D510F51880083DE81
      Reviewed on
      2026-08-31
      Source IDH51-D9D16397EEB662E37825D239
      Mechanism source
      Concise GlobalRPh summary reviewed against the selected DailyMed label clinical-pharmacology or microbiology content.
      Source IDH51-20262BF1D3E8AD5F6735ADBD
      Source sections
      1. Dosage and Administration
        Source IDH51-56264A75F49C82F45621B00A
      2. Dosage Forms and Strengths
        Source IDH51-6E98CE6EE4522C6EDEE0874F
      3. Clinical Pharmacology or Microbiology as applicable
        Source IDH51-51BEAD0D9082D3BBFFF6B0B0
      Retrieval method
      Manual build-time review of the current DailyMed full prescribing information for the selected Set ID; no live server retrieval is required during page use.
      Source IDH51-553B3EF78C7E0A3E1A2FBC70
      Label status
      current
      Source IDH51-31D2118EDB21F81D42660F24
      Disclaimer
      Verify the exact formulation, strength, manufacturer, NDC, route, current label revision, patient-specific order, institutional policy, and monitoring before use.
      Source IDH51-2C075E4B34D13653FCD3EF84

      Historical indication and population dosing

      Recovered tables and source-separated snapshots; full clinical revalidation remains pending.

      Existing dose and route snapshots

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      RoutePopulationIndicationDoseIntervalDurationAdministrationSource levelNotes
      Source IDH51-1F72E592F3D54B56D02D0996
      IV infusion
      Source IDH51-D45580C63FE9BC59E9164034
      		Adult, normal renal function
      Source IDH51-4E46FE44C4C2AE39C7F82302
      		Existing preparation record; use current package insert for indication-specific selection
      Source IDH51-A913BD271B91EC6133D3DB7B
      		4 g total (2 g meropenem/2 g vaborbactam) every 8 hours
      Source IDH51-6296CEC24491D25287AA3228
      		Not normalized in the preparation record
      Source IDH51-053BCEA1C69F75748F777481
      		See current package insert and professional guidance
      Source IDH51-58E735BA2463DACAB3279F33
      		Infuse over 3 hours
      Source IDH51-767B5F29B2E090CC71F79AE3
      		Existing GlobalRPh structured preparation snapshot
      Source IDH51-9B8A64BEFDE93C482BEEB94A
      		Renal adjustment is required and dosing is timed from the start of infusion.
      Source IDH51-1BC22BB973C74B00378C712E

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      adjustment_required
      Source IDH51-03548D1462FEFBFE58C1ACF7
      Summary
      Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method.
      Source IDH51-2510D491AB6EF27A3EA9B8AD
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-95FE3B7016CD07310D24CE2A

      Historical Common IV uses

      Recovered v5.1 source content; historical, awaiting current review.

      1. Complicated urinary infection including pyelonephritis in adults
        Source IDH51-6F36EE82C94F66910EAA7252

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Seizure risk and valproate interaction from meropenem component.
        Source IDH51-9D473EFBB9B8F8C42968AB8F
      2. Serious beta-lactam hypersensitivity.
        Source IDH51-0E294D32A2814721653733E6

      Historical Monitoring

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      1. Renal function
        Source IDH51-2DE9280938A0C958F4C75369
      2. Neurologic status
        Source IDH51-3FD33BFCBE574CFD123FB732
      3. Clinical response
        Source IDH51-DA2E6936B9E06E8B8FF4A0E3

      Historical supplemental professional sources

      Recovered v5.1 source content; historical, awaiting current review.

      LabelUrlKind
      Source IDH51-39EA75AC147506C9EEDC088B
      UCSF adult antimicrobial dosing, non-dialysis
      Source IDH51-FD98F61A88E271B39977BB52
      		https://idmp.ucsf.edu/adult-antimicrobial-dosing-non-dialysis (opens in a new tab)
      Source IDH51-D1745173C7AD7A34EDF3AED7
      		Professional institutional guidance
      Source IDH51-301C1ED1493BAF75B1D53467
      Source IDH51-BE1423ADDBAFB2355BAA2554
      UCSF antimicrobial dosing in intermittent and continuous hemodialysis
      Source IDH51-7660FCD35387760CD98A3C4C
      		https://idmp.ucsf.edu/antimicrobial-dosing-intermittent-continuous-hemodialysis (opens in a new tab)
      Source IDH51-93336AF79B8F49268A1E9B4F
      		Professional institutional guidance
      Source IDH51-BE680558032C15D98142AC9F
      Source IDH51-66023D8ABC8529844031D954
      UCSF pediatric antimicrobial dosing
      Source IDH51-3032608766388A23701B953C
      		https://idmp.ucsf.edu/pediatric-antimicrobial-dosing-benioff-childrens-hospitals (opens in a new tab)
      Source IDH51-E69DC64164413C6DE23CA286
      		Professional institutional guidance
      Source IDH51-633A715450847EC6F2E95E87
      Source IDH51-BC8AB7B030963CA256F89FF8
      UCSF neonatal antimicrobial dosing
      Source IDH51-8AB14879C66F989D4924B925
      		https://idmp.ucsf.edu/neonatal-antimicrobial-dosing-benioff-childrens-hospitals (opens in a new tab)
      Source IDH51-DD4524364945A9C286156B88
      		Professional institutional guidance
      Source IDH51-B6D6F193450027A3F9B143B0
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      meropenem-vaborbactam
      Source IDH51-D930A6E10AEDCF054A348218
      Generic name
      Meropenem-vaborbactam
      Source IDH51-E2DEAF526A1FA39652549C37
      Brand names
      1. Vabomere
        Source IDH51-B4599BF3C3CDD285A406704F
      Class
      Antibacterial
      Source IDH51-BC78D20ED2EECC1B4BCAC1CF
      Subclass
      Carbapenem plus beta-lactamase inhibitor
      Source IDH51-CD5610D909DE32360C80D01E
      Summary
      Fixed 1:1 product supplied as 2 g per vial; the standard adult dose uses two vials and a three-hour infusion.
      Source IDH51-08117D6281199B687D1E8524
      Populations
      1. Adult
        Source IDH51-2498E35D4A1FA11D42B77A97
      Evidence tier
      Enhanced current-label framework
      Source IDH51-A1BDC8F621BD451A71C014F1
      High alert
      false
      Source IDH51-262672D6A7E9685E7C37E2B1
      Hazardous
      false
      Source IDH51-35B4F3A13E4040616CE47E5D
      Status
      Active
      Source IDH51-6CFF02C5DE7862D01732B671
      Reviewed
      2026-08-29
      Source IDH51-26F4398449E8128AF4FF19EA
      Version added
      1.2
      Source IDH51-FE121663EFD35792FF8E1CC4
      Sources
      LabelUrlKind
      Source IDH51-7D88D2904FCA62412727591C
      DailyMed label search
      Source IDH51-08ADB5E1DFAD7AD5607FB298
      		https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Meropenem-vaborbactam (opens in a new tab)
      Source IDH51-7C6F10A3E67FE62C9054EC40
      		Primary
      Source IDH51-1F287B0756365F9522F15D2B
      Source IDH51-BB175D2B5FA23BE7C914C02D
      GlobalRPh legacy IV dilution monograph
      Source IDH51-E0CB606513B3F424B30F0C19
      		legacy:auto
      Source IDH51-3E729CB709224C5285A784EE
      		Legacy
      Source IDH51-106AB329C56D0968AF56B4B7
      Clinical release verification
      Audit version
      3.4
      Source IDH51-F1E02C002BF2719F4C514C34
      Audited on
      2026-08-30
      Source IDH51-4858DFB464BF53F4646A6D6B
      Level
      amber
      Source IDH51-A36BC27D7B35EC8F9CE85137
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-1625C0B4D6452A83BB32FE5F
      Exact current label candidate
      false
      Source IDH51-FA1095E9665C618F5843CA9F
      Numeric support ratio
      0
      Source IDH51-B3F8D1907ACFFC34A1B0BE6C
      Reference url count
      5
      Source IDH51-67A270400621880747345B48
      Broken reference count
      0
      Source IDH51-0D0891C462B17541ACB28CC3
      Point of use confirmation required
      true
      Source IDH51-9B1D612FD4C2A75DAF3E9FA8
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-E3E4AD41BC3D1AAAE4B74E57
      Version updated
      5.1
      Source IDH51-0214A21D46405B895CB7D8C9

      Dosing source fields

      Id
      meropenem-vaborbactam
      Source IDH51-FA37113AA0C5F3DAF3BB93F0
      Generic name
      Meropenem-vaborbactam
      Source IDH51-81D6F44A3F6558552930B8AC
      Coverage status
      direct_official_label_access_plus_local_snapshot
      Source IDH51-C790436862A0A65CB31EB37F
      Package insert
      Query name
      Meropenem-vaborbactam
      Source IDH51-58A03E2ABE6AA7378A6EC4C2
      Product and route must match
      true
      Source IDH51-CB14DAA2F9E039F8F555F450
      Live current label enabled
      false
      Source IDH51-FBAF5F613B8A328128E9F7C2
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-4CC01E8A7A33CCC3975439BC
      Direct official label access enabled
      true
      Source IDH51-F468733CF0E19DF08A813B83
      Outbound server request required
      false
      Source IDH51-69F0CEF3BEB3788F1EFE0C24
      Local summary status
      not_bundled
      Source IDH51-44F0BECA7C3096A5F9ED7752
      Clinical review
      Locally normalized
      false
      Source IDH51-D1DE007EB341A3589E2A4B66
      Reviewed
      2026-08-29
      Source IDH51-DE5DAF90D9B0F1207884C3ED
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-A8F5DBE0831A8A12170293BD
      Clinical release verification
      Audit version
      3.4
      Source IDH51-72C8824C18C84D81BE0BB2C9
      Audited on
      2026-08-30
      Source IDH51-9DF7872550E0A7D13E0DA482
      Level
      amber
      Source IDH51-D25E5B181EA1516594CA66FD
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-9FC18A3FDFC8C292136BC186
      Exact current label candidate
      false
      Source IDH51-0D0CA5FB1B8B8F090A06162B
      Numeric support ratio
      0
      Source IDH51-AB9A5B9642C1A88AE613E4E8
      Reference url count
      5
      Source IDH51-D6CE61222139083AF410F081
      Broken reference count
      0
      Source IDH51-7A417D9E215A2F1B2E0B8749
      Point of use confirmation required
      true
      Source IDH51-4CBFADB9C93302A43A6EE854
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-417780E8D48AFBF0D317D25F
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      meropenem-vaborbactam
      Source IDH51-C88BA82CDAEDA5309AB1F011
      Name
      Meropenem-vaborbactam
      Source IDH51-A0621C26072C0B34CB384860
      Brands
      Vabomere
      Source IDH51-E83206BCB3097AB23448B531
      Therapeutic class
      Antibacterial
      Source IDH51-CFDC8480EDB1E61E8511B193
      Review version
      3.1
      Source IDH51-3DC553DE5419E0F08F2323D3
      Review date
      2026-08-30
      Source IDH51-DB398C980DC08F637D39BC35
      Release status
      structured_record_current_label_not_confirmed
      Source IDH51-958C71D417B35046431793C9
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-1C02594D4707867E6AC182D4
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-A3897D812945AF510FE52309
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-249355B79AE83B2D325C7E0A
      Reconstitution concentration
      Reconstitute two vials as directed by current labeling and combine the required contents.
      Source IDH51-9C826C84E0136EF2B2A3D8A0
      Maximum or recommended final concentration
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-024891B416F73DEFC5D08573
      Appropriate standardized containers
      250 mL commonly
      Source IDH51-82979795765EB913CDF82B82
      Adult dosing range
      4 g total (2 g meropenem/2 g vaborbactam) every 8 hours
      Source IDH51-BCF68542AD99C9767F1708CC
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-1648F27AE16AC6D152172984
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-713E46E866C41092FBFF2BC2
      Infusion time
      Infuse over 3 hours
      Source IDH51-14F44217434616D0E75A86BE
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-661403108EEC359C32344FB8
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-63E09DEC4FD10C5CED70AFC6
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-1BA4EA766EE3D4B3F96545C3
      Reconstitution concentration
      Primary
      existing_structured_record
      Source IDH51-D6E2A2DD4A896548D9E9CC82
      Maximum or recommended final concentration
      Primary
      not_found
      Source IDH51-5FF018C051DE77E696D52E28
      Appropriate standardized containers
      Primary
      existing_structured_record
      Source IDH51-D7345FB9402F6AE7DBC5E3F2
      Adult dosing range
      Primary
      existing_structured_record
      Source IDH51-D1D1987E017EDFFE1A2C5CA6
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-83D0248DE987E19E442B053B
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-F015D1F7A401823DEA9DFFA1
      Infusion time
      Primary
      existing_structured_record
      Source IDH51-D822D48D5D998A55EBBCDD89
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-188C34DC3D2E3EDF8D514C8C
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-8E44221FE7FDEB243A5BDADA
      Population applicability
      Adult
      Applicability
      supported_or_source_present
      Source IDH51-4ECB5CBBEB903FDE824862D2
      Guide generation allowed
      true
      Source IDH51-6E4F0D4FBAAAA96158B99D92
      Pediatric
      Applicability
      supported_or_source_present
      Source IDH51-2443099282C52C43371DE66C
      Guide generation allowed
      false
      Source IDH51-86DB97BEA64A2C55802BFF46
      Neonatal
      Applicability
      supported_or_source_present
      Source IDH51-8D2BF33284DEFB9FD23B652F
      Guide generation allowed
      false
      Source IDH51-42A7A99707D9AA6FB6C7E61C
      Route presence
      Structured dilution
      true
      Source IDH51-15EDE424AB10B8E937DF2E92
      Iv push
      false
      Source IDH51-B681429D0E5C3753F1D640A7
      Continuous infusion
      false
      Source IDH51-8291EEA824F7FDA45DDDEF15
      Pediatric source
      true
      Source IDH51-71AC4B776052C7A7304FB7F5
      Neonatal source
      true
      Source IDH51-83ADB5017483838CB2385598
      Legacy reference
      Status
      not_available
      Source IDH51-625EFCC5D8BF4BDD22F31E38
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-A27E9A49AD88D198BE5A6019
      Source files
      1. catalog.json
        Source IDH51-72F60DB2E7F087140769A455
      2. dosing.json
        Source IDH51-5EA1178F6150D815F8BEE5B1
      3. new-in-v1.2.json
        Source IDH51-E8147B5546858BFCAAA41A40
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-82257A1162CBB16FD4747E2E
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-D930A6E10AEDCF054A348218catalog.json
      /records/158/id      		Historical; current review incomplete
      H51-E2DEAF526A1FA39652549C37catalog.json
      /records/158/generic_name      		Historical; current review incomplete
      H51-B4599BF3C3CDD285A406704Fcatalog.json
      /records/158/brand_names/0      		Historical; current review incomplete
      H51-BC78D20ED2EECC1B4BCAC1CFcatalog.json
      /records/158/class      		Historical; current review incomplete
      H51-CD5610D909DE32360C80D01Ecatalog.json
      /records/158/subclass      		Historical; current review incomplete
      H51-08117D6281199B687D1E8524catalog.json
      /records/158/summary      		Historical; current review incomplete
      H51-6F36EE82C94F66910EAA7252catalog.json
      /records/158/common_uses/0      		Historical; current review incomplete
      H51-DFE5E0808037D7B731537686catalog.json
      /records/158/preparations/0      		Historical; current review incomplete
      H51-90F9FC84382EFDAEC7525834catalog.json
      /records/158/preparations/0/population      		Historical; current review incomplete
      H51-3B2461AD9EF6818E4A2D4504catalog.json
      /records/158/preparations/0/amount      		Historical; current review incomplete
      H51-D0D8A0184C4AC07945A9B926catalog.json
      /records/158/preparations/0/reconstitution      		Historical; current review incomplete
      H51-3635137A87D80D68C00AC65Bcatalog.json
      /records/158/preparations/0/diluent      		Historical; current review incomplete
      H51-59C7A41140B7D7449649E856catalog.json
      /records/158/preparations/0/final_volume      		Historical; current review incomplete
      H51-EF78D8A9FA7E8FB08EC2A98Acatalog.json
      /records/158/preparations/0/concentration      		Historical; current review incomplete
      H51-1334C5952A9A63EE7DB34771catalog.json
      /records/158/preparations/0/rate      		Historical; current review incomplete
      H51-5D28A0822EEB7FFC887B49C6catalog.json
      /records/158/preparations/0/stability      		Historical; current review incomplete
      H51-2A5BFF22F14036BA66A332CEcatalog.json
      /records/158/preparations/0/notes      		Historical; current review incomplete
      H51-9D473EFBB9B8F8C42968AB8Fcatalog.json
      /records/158/warnings/0      		Historical; current review incomplete
      H51-0E294D32A2814721653733E6catalog.json
      /records/158/warnings/1      		Historical; current review incomplete
      H51-2DE9280938A0C958F4C75369catalog.json
      /records/158/monitoring/0      		Historical; current review incomplete
      H51-3FD33BFCBE574CFD123FB732catalog.json
      /records/158/monitoring/1      		Historical; current review incomplete
      H51-DA2E6936B9E06E8B8FF4A0E3catalog.json
      /records/158/monitoring/2      		Historical; current review incomplete
      H51-2498E35D4A1FA11D42B77A97catalog.json
      /records/158/populations/0      		Historical; current review incomplete
      H51-A1BDC8F621BD451A71C014F1catalog.json
      /records/158/evidence_tier      		Historical; current review incomplete
      H51-262672D6A7E9685E7C37E2B1catalog.json
      /records/158/high_alert      		Historical; current review incomplete
      H51-35B4F3A13E4040616CE47E5Dcatalog.json
      /records/158/hazardous      		Historical; current review incomplete
      H51-6CFF02C5DE7862D01732B671catalog.json
      /records/158/status      		Historical; current review incomplete
      H51-26F4398449E8128AF4FF19EAcatalog.json
      /records/158/reviewed      		Historical; current review incomplete
      H51-FE121663EFD35792FF8E1CC4catalog.json
      /records/158/version_added      		Historical; current review incomplete
      H51-7D88D2904FCA62412727591Ccatalog.json
      /records/158/sources/0      		Historical; current review incomplete
      H51-08ADB5E1DFAD7AD5607FB298catalog.json
      /records/158/sources/0/label      		Historical; current review incomplete
      H51-7C6F10A3E67FE62C9054EC40catalog.json
      /records/158/sources/0/url      		Historical; current review incomplete
      H51-1F287B0756365F9522F15D2Bcatalog.json
      /records/158/sources/0/kind      		Historical; current review incomplete
      H51-BB175D2B5FA23BE7C914C02Dcatalog.json
      /records/158/sources/1      		Historical; current review incomplete
      H51-E0CB606513B3F424B30F0C19catalog.json
      /records/158/sources/1/label      		Historical; current review incomplete
      H51-3E729CB709224C5285A784EEcatalog.json
      /records/158/sources/1/url      		Historical; current review incomplete
      H51-106AB329C56D0968AF56B4B7catalog.json
      /records/158/sources/1/kind      		Historical; current review incomplete
      H51-3AC801367FB68E75CC54B131catalog.json
      /records/158/legacy_title      		Historical; current review incomplete
      H51-F1E02C002BF2719F4C514C34catalog.json
      /records/158/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-4858DFB464BF53F4646A6D6Bcatalog.json
      /records/158/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-A36BC27D7B35EC8F9CE85137catalog.json
      /records/158/clinical_release_verification/level      		Historical; current review incomplete
      H51-1625C0B4D6452A83BB32FE5Fcatalog.json
      /records/158/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-FA1095E9665C618F5843CA9Fcatalog.json
      /records/158/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-BEBAE5649E914974E8ACAED5catalog.json
      /records/158/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-C9835AA61A856B278D35910Fcatalog.json
      /records/158/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-B3F8D1907ACFFC34A1B0BE6Ccatalog.json
      /records/158/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-67A270400621880747345B48catalog.json
      /records/158/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-0D0891C462B17541ACB28CC3catalog.json
      /records/158/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-9B1D612FD4C2A75DAF3E9FA8catalog.json
      /records/158/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-E3E4AD41BC3D1AAAE4B74E57catalog.json
      /records/158/clinical_release_verification/note      		Historical; current review incomplete
      H51-DBC16769E12914512E858649catalog.json
      /records/158/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-0214A21D46405B895CB7D8C9catalog.json
      /records/158/version_updated      		Historical; current review incomplete
      H51-DB88D53056ABFB51E9CE2581dailymed-label-snapshots-v5.1.json
      /records/38/id      		Historical; current review incomplete
      H51-3F09E95C6BD5CDF13CB1C1F0dailymed-label-snapshots-v5.1.json
      /records/38/catalog_name      		Historical; current review incomplete
      H51-30F18BFA9CCED932837C02EAdailymed-label-snapshots-v5.1.json
      /records/38/selection_status      		Historical; current review incomplete
      H51-41ED9EFC02F2460A41BF0299dailymed-label-snapshots-v5.1.json
      /records/38/confidence      		Historical; current review incomplete
      H51-F0FA46444A2A96D4DA0D6E94dailymed-label-snapshots-v5.1.json
      /records/38/match_path      		Historical; current review incomplete
      H51-BB9A8D1F597CF599998E4DE0dailymed-label-snapshots-v5.1.json
      /records/38/brand_name      		Historical; current review incomplete
      H51-DE4B39613661675BBA6762C0dailymed-label-snapshots-v5.1.json
      /records/38/label_title      		Historical; current review incomplete
      H51-64BC7D88896ADF2C88D486B0dailymed-label-snapshots-v5.1.json
      /records/38/setid      		Historical; current review incomplete
      H51-A47692571346CE761C8230D9dailymed-label-snapshots-v5.1.json
      /records/38/route      		Historical; current review incomplete
      H51-2DCFE6F8E15F0D438E404EBFdailymed-label-snapshots-v5.1.json
      /records/38/dosage_form      		Historical; current review incomplete
      H51-97B18E590B87AD065D5C2DEEdailymed-label-snapshots-v5.1.json
      /records/38/dosage_administration_summary/0      		Historical; current review incomplete
      H51-EE1D2CABC0910CF8EFBABA88dailymed-label-snapshots-v5.1.json
      /records/38/dosage_administration_summary/1      		Historical; current review incomplete
      H51-2FBF8029133F23D2B5CBBC50dailymed-label-snapshots-v5.1.json
      /records/38/dosage_administration_summary/2      		Historical; current review incomplete
      H51-AAAAF34E669A30143BE09973dailymed-label-snapshots-v5.1.json
      /records/38/dosage_forms_strengths/0      		Historical; current review incomplete
      H51-F5A36F74C5BFBA3D03B7B2E0dailymed-label-snapshots-v5.1.json
      /records/38/mechanism_summary      		Historical; current review incomplete
      H51-A1F67F6D510F51880083DE81dailymed-label-snapshots-v5.1.json
      /records/38/scope_note      		Historical; current review incomplete
      H51-F4277CE19A4359C3FD4EB617dailymed-label-snapshots-v5.1.json
      /records/38/labeler      		Historical; current review incomplete
      H51-6FC9A5215EE98CC4707B7F44dailymed-label-snapshots-v5.1.json
      /records/38/official_label_url      		Historical; current review incomplete
      H51-D9D16397EEB662E37825D239dailymed-label-snapshots-v5.1.json
      /records/38/reviewed_on      		Historical; current review incomplete
      H51-20262BF1D3E8AD5F6735ADBDdailymed-label-snapshots-v5.1.json
      /records/38/mechanism_source      		Historical; current review incomplete
      H51-56264A75F49C82F45621B00Adailymed-label-snapshots-v5.1.json
      /records/38/source_sections/0      		Historical; current review incomplete
      H51-6E98CE6EE4522C6EDEE0874Fdailymed-label-snapshots-v5.1.json
      /records/38/source_sections/1      		Historical; current review incomplete
      H51-51BEAD0D9082D3BBFFF6B0B0dailymed-label-snapshots-v5.1.json
      /records/38/source_sections/2      		Historical; current review incomplete
      H51-553B3EF78C7E0A3E1A2FBC70dailymed-label-snapshots-v5.1.json
      /records/38/retrieval_method      		Historical; current review incomplete
      H51-31D2118EDB21F81D42660F24dailymed-label-snapshots-v5.1.json
      /records/38/label_status      		Historical; current review incomplete
      H51-2C075E4B34D13653FCD3EF84dailymed-label-snapshots-v5.1.json
      /records/38/disclaimer      		Historical; current review incomplete
      H51-FA37113AA0C5F3DAF3BB93F0dosing.json
      /records/158/id      		Historical; current review incomplete
      H51-81D6F44A3F6558552930B8ACdosing.json
      /records/158/generic_name      		Historical; current review incomplete
      H51-C790436862A0A65CB31EB37Fdosing.json
      /records/158/coverage_status      		Historical; current review incomplete
      H51-58A03E2ABE6AA7378A6EC4C2dosing.json
      /records/158/package_insert/query_name      		Historical; current review incomplete
      H51-3994379BCA431F22BB35B627dosing.json
      /records/158/package_insert/preferred_setid      		Historical; current review incomplete
      H51-CB14DAA2F9E039F8F555F450dosing.json
      /records/158/package_insert/product_and_route_must_match      		Historical; current review incomplete
      H51-FBAF5F613B8A328128E9F7C2dosing.json
      /records/158/package_insert/live_current_label_enabled      		Historical; current review incomplete
      H51-4CC01E8A7A33CCC3975439BCdosing.json
      /records/158/package_insert/source_priority      		Historical; current review incomplete
      H51-F468733CF0E19DF08A813B83dosing.json
      /records/158/package_insert/direct_official_label_access_enabled      		Historical; current review incomplete
      H51-69F0CEF3BEB3788F1EFE0C24dosing.json
      /records/158/package_insert/outbound_server_request_required      		Historical; current review incomplete
      H51-44F0BECA7C3096A5F9ED7752dosing.json
      /records/158/package_insert/local_summary_status      		Historical; current review incomplete
      H51-03548D1462FEFBFE58C1ACF7dosing.json
      /records/158/renal/classification      		Historical; current review incomplete
      H51-2510D491AB6EF27A3EA9B8ADdosing.json
      /records/158/renal/summary      		Historical; current review incomplete
      H51-95FE3B7016CD07310D24CE2Adosing.json
      /records/158/renal/method_note      		Historical; current review incomplete
      H51-1F72E592F3D54B56D02D0996dosing.json
      /records/158/existing_route_snapshots/0      		Historical; current review incomplete
      H51-D45580C63FE9BC59E9164034dosing.json
      /records/158/existing_route_snapshots/0/route      		Historical; current review incomplete
      H51-4E46FE44C4C2AE39C7F82302dosing.json
      /records/158/existing_route_snapshots/0/population      		Historical; current review incomplete
      H51-A913BD271B91EC6133D3DB7Bdosing.json
      /records/158/existing_route_snapshots/0/indication      		Historical; current review incomplete
      H51-6296CEC24491D25287AA3228dosing.json
      /records/158/existing_route_snapshots/0/dose      		Historical; current review incomplete
      H51-053BCEA1C69F75748F777481dosing.json
      /records/158/existing_route_snapshots/0/interval      		Historical; current review incomplete
      H51-58E735BA2463DACAB3279F33dosing.json
      /records/158/existing_route_snapshots/0/duration      		Historical; current review incomplete
      H51-767B5F29B2E090CC71F79AE3dosing.json
      /records/158/existing_route_snapshots/0/administration      		Historical; current review incomplete
      H51-9B8A64BEFDE93C482BEEB94Adosing.json
      /records/158/existing_route_snapshots/0/source_level      		Historical; current review incomplete
      H51-1BC22BB973C74B00378C712Edosing.json
      /records/158/existing_route_snapshots/0/notes      		Historical; current review incomplete
      H51-39EA75AC147506C9EEDC088Bdosing.json
      /records/158/professional_sources/0      		Historical; current review incomplete
      H51-FD98F61A88E271B39977BB52dosing.json
      /records/158/professional_sources/0/label      		Historical; current review incomplete
      H51-D1745173C7AD7A34EDF3AED7dosing.json
      /records/158/professional_sources/0/url      		Historical; current review incomplete
      H51-301C1ED1493BAF75B1D53467dosing.json
      /records/158/professional_sources/0/kind      		Historical; current review incomplete
      H51-BE1423ADDBAFB2355BAA2554dosing.json
      /records/158/professional_sources/1      		Historical; current review incomplete
      H51-7660FCD35387760CD98A3C4Cdosing.json
      /records/158/professional_sources/1/label      		Historical; current review incomplete
      H51-93336AF79B8F49268A1E9B4Fdosing.json
      /records/158/professional_sources/1/url      		Historical; current review incomplete
      H51-BE680558032C15D98142AC9Fdosing.json
      /records/158/professional_sources/1/kind      		Historical; current review incomplete
      H51-66023D8ABC8529844031D954dosing.json
      /records/158/professional_sources/2      		Historical; current review incomplete
      H51-3032608766388A23701B953Cdosing.json
      /records/158/professional_sources/2/label      		Historical; current review incomplete
      H51-E69DC64164413C6DE23CA286dosing.json
      /records/158/professional_sources/2/url      		Historical; current review incomplete
      H51-633A715450847EC6F2E95E87dosing.json
      /records/158/professional_sources/2/kind      		Historical; current review incomplete
      H51-BC8AB7B030963CA256F89FF8dosing.json
      /records/158/professional_sources/3      		Historical; current review incomplete
      H51-8AB14879C66F989D4924B925dosing.json
      /records/158/professional_sources/3/label      		Historical; current review incomplete
      H51-DD4524364945A9C286156B88dosing.json
      /records/158/professional_sources/3/url      		Historical; current review incomplete
      H51-B6D6F193450027A3F9B143B0dosing.json
      /records/158/professional_sources/3/kind      		Historical; current review incomplete
      H51-D1DE007EB341A3589E2A4B66dosing.json
      /records/158/clinical_review/locally_normalized      		Historical; current review incomplete
      H51-DE5DAF90D9B0F1207884C3EDdosing.json
      /records/158/clinical_review/reviewed      		Historical; current review incomplete
      H51-A8F5DBE0831A8A12170293BDdosing.json
      /records/158/clinical_review/status      		Historical; current review incomplete
      H51-72C8824C18C84D81BE0BB2C9dosing.json
      /records/158/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-9DF7872550E0A7D13E0DA482dosing.json
      /records/158/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-D25E5B181EA1516594CA66FDdosing.json
      /records/158/clinical_release_verification/level      		Historical; current review incomplete
      H51-9FC18A3FDFC8C292136BC186dosing.json
      /records/158/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-0D0CA5FB1B8B8F090A06162Bdosing.json
      /records/158/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-67195B2090A8BBEB6CB0B73Edosing.json
      /records/158/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-28A86C0DCCFD7C56BBADF53Edosing.json
      /records/158/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-AB9A5B9642C1A88AE613E4E8dosing.json
      /records/158/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-D6CE61222139083AF410F081dosing.json
      /records/158/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-7A417D9E215A2F1B2E0B8749dosing.json
      /records/158/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-4CBFADB9C93302A43A6EE854dosing.json
      /records/158/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-417780E8D48AFBF0D317D25Fdosing.json
      /records/158/clinical_release_verification/note      		Historical; current review incomplete
      H51-7A321FAA6B5A212D989898DEdosing.json
      /records/158/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-585E09797EEFCAD7E29A7D3Bfirst-look-v5.1.json
      /records/158/id      		Historical; current review incomplete
      H51-2B8E105B88A1E56D1CBCA788first-look-v5.1.json
      /records/158/generic_name      		Historical; current review incomplete
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      H51-FC45CA4519F0E54452098790first-look-v5.1.json
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      H51-C88BA82CDAEDA5309AB1F011preparation-assessments-v3.8.json
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      /158/route_presence/structured_dilution      		Historical; current review incomplete
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      /158/route_presence/iv_push      		Historical; current review incomplete
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      /158/route_presence/continuous_infusion      		Historical; current review incomplete
      H51-71AC4B776052C7A7304FB7F5preparation-assessments-v3.8.json
      /158/route_presence/pediatric_source      		Historical; current review incomplete
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      /158/legacy_reference/status      		Historical; current review incomplete
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      /158/label_resolution/status      		Historical; current review incomplete
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      /158/source_files/0      		Historical; current review incomplete
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      /158/clinical_release_note      		Historical; current review incomplete
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