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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Medication reference

Ketamine

Monograph awaiting updateThis monograph will be updated in the future.

Jump to a section

No original site article was mapped to this record. The available historical structured fields and official-source links are retained.

Historical first look: uses, mechanism, dosing context, and administration

Recovered v5.1 source content; historical, awaiting current review.

Id
ketamine
Source IDH51-06AC1C52FF2D1CD765EDCE8B
Generic name
Ketamine
Source IDH51-E9462E9B95F25C47AA429488
Class
Sedation, analgesia, and anesthesia
Source IDH51-6BAA342F0EC6F7385C1ADBF7
Subclass
Dissociative anesthetic and analgesic
Source IDH51-6A986A3A72376F34B1B6F52E
Primary uses
  1. Induction
    Source IDH51-9C80315B35F4BFC09F134F58
  2. Procedural sedation
    Source IDH51-11E040D65092C2362E90F549
  3. Subanesthetic analgesia
    Source IDH51-304DE7E39DF88F5138B8897F
  4. Selected refractory status asthmaticus or status epilepticus protocols
    Source IDH51-39440CA66D1D8D467A8DE69E
Mechanism
Noncompetitively blocks NMDA receptors and modulates additional analgesic and anesthetic pathways.
Source IDH51-FA946C3E775BBFCFDEE82691
Mechanism level
drug_specific
Source IDH51-456BC177D4B405A2BA04B5A5
Basic dosing orientation
Adult analgesic infusion | Existing preparation record; use current package insert for indication-specific selection | Prepare standardized concentration | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult induction | Commonly 1 to 2 mg/kg | Commonly 1 to 2 mg/kg | Patient- and indication-specific | See current package insert | IV push
Source IDH51-68B861C229E0FD28A295798D
Administration orientation
Commonly 0.05 to 0.4 mg/kg/hour under protocol; Over 30 to 60 seconds; 10 to 50 mg/mL commonly; Over 30 to 60 seconds
Source IDH51-82F321ED6C442BBE94FC154C
Renal and population orientation
Separate renal reference: Open Renal Dosing Master (opens in a new tab)Renal dosing status has not been locally normalized; use the current package insert before ordering or administration.
Source IDH51-63E4652BB1EFD3DE69E2E069
Key safety orientation
  1. Hypertension, tachycardia, emergence reactions, hypersalivation, and rare laryngospasm.
    Source IDH51-523E49062E5B17093E6B29D3
  2. Respiratory depression can occur with rapid/high doses or sedative combinations.
    Source IDH51-403A7ED50E020DE3C1A5DD79
Coverage path
structured_local_snapshot
Source IDH51-FFE509A6737B399F51CEECEA
Coverage path label
Structured GlobalRPh route snapshot
Source IDH51-C1CD1EDB41B5093CAB823E01
Review note
First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
Source IDH51-7ECD987B13C95B211AE64774
Search text
Ketamine Sedation, analgesia, and anesthesia Dissociative anesthetic and analgesic Induction Procedural sedation Subanesthetic analgesia Selected refractory status asthmaticus or status epilepticus protocols Noncompetitively blocks NMDA receptors and modulates additional analgesic and anesthetic pathways. Adult analgesic infusion | Existing preparation record; use current package insert for indication-specific selection | Prepare standardized concentration | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult induction | Commonly 1 to 2 mg/kg | Commonly 1 to 2 mg/kg | Patient- and indication-specific | See current package insert | IV push Commonly 0.05 to 0.4 mg/kg/hour under protocol; Over 30 to 60 seconds; 10 to 50 mg/mL commonly; Over 30 to 60 seconds Renal dosing status has not been locally normalized; use the current package insert before ordering or administration. Hypertension, tachycardia, emergence reactions, hypersalivation, and rare laryngospasm. Respiratory depression can occur with rapid/high doses or sedative combinations. Structured GlobalRPh route snapshot
Source IDH51-3CB66171826E9338C290DC87
Official access mode
search
Source IDH51-1CF02453815C101F5B77311F
Official search query
Ketamine
Source IDH51-CF9AA68235748C8FBED79E1D
Official access reason
A source-backed DailyMed search is available; select and confirm the exact IV product.
Source IDH51-48452179BC7E1A18183AD503
Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • Retrievable exact-product SPL XML with version, revision, retrieval date and reproducible hash
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
current_label_review_required
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.

      No separate structured rows were bundled for dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical dilution and intermittent infusion preparation

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationAmountReconstitutionDiluentFinal volumeConcentrationRateStabilityNotes
      Source IDH51-66905812ED78D44655A1F376
      Adult analgesic infusion
      Source IDH51-1B9F0D55B72798DFF1242E5A
      Prepare standardized concentration
      Source IDH51-25E2FB82377AA3C01D503BDC
      Dilute 10, 50, or 100 mg/mL product as needed.
      Source IDH51-E5491931D3130F2178BF48C2
      NS or D5W
      Source IDH51-5BAB32C44E2AB1215ADAEA93
      50 to 250 mL
      Source IDH51-71F99C2894D028D8E10F3AE7
      Commonly 1 to 2 mg/mL
      Source IDH51-EA008783678476A5947947FE
      Commonly 0.05 to 0.4 mg/kg/hour under protocol
      Source IDH51-44235B626E9EC4F3661C8034
      Use the shorter of current product labeling, validated stability data, and the applicable USP <797> sterility-based BUD ceiling.
      Source IDH51-B0A269786A0F0E06DB3E43A6
      Do not use anesthetic-range dosing without airway-level monitoring.
      Source IDH51-441B7FB44D909E71ABB19BB9

      Historical IV-push guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationDose scopeConcentrationRateStatusNotes
      Source IDH51-052C2D19DB771192704366EE
      Adult induction
      Source IDH51-6D6401D9F0634FA3B6F17698
      Commonly 1 to 2 mg/kg
      Source IDH51-7F4C07EEC0C5CAC487591490
      10 to 50 mg/mL commonly
      Source IDH51-EFFCBB64363C12E826339D19
      Over 30 to 60 seconds
      Source IDH51-B4E86FD95BD23EC6C9C25B6F
      Airway/anesthesia protocol only
      Source IDH51-36CD45F5923FE7A08DEB2C2F
      Source IDH51-86F603C32A26B14AC78A3621
      Adult analgesia
      Source IDH51-7924466E5888CA20C1968A91
      Commonly 0.1 to 0.3 mg/kg
      Source IDH51-B42926E8282D3E310C309830
      Dilute for controlled administration
      Source IDH51-A7FE34E750E0AEBF42A666CE
      Over 10 to 15 minutes rather than rapid push
      Source IDH51-253C1FEC8280B8B5FE993DD7
      Protocol-controlled
      Source IDH51-B9A7648392E21826C59F932E
      Slower administration reduces psychoperceptual and hemodynamic effects.
      Source IDH51-C490063A8A8ACB595A028B4F

      Historical continuous-infusion guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationStandard concentrationInitial rateTitrationMaximumNotes
      Source IDH51-0582F86CC7D9CBE5241B2DC4
      Adult analgesia
      Source IDH51-EB41D39D318181F8641DB19F
      1 to 2 mg/mL
      Source IDH51-59D9A84783F655895B867371
      0.05 to 0.1 mg/kg/hour
      Source IDH51-93E3F3B8754ABDE13048058D
      Titrate to pain and adverse effects
      Source IDH51-34C08F49AB3AC50BA2D24C4B
      Commonly 0.4 mg/kg/hour in subanesthetic protocols
      Source IDH51-5BCDE5500BE918024F398590
      Higher sedation/anesthesia doses require distinct protocols.
      Source IDH51-A38A6A340F4D9259C259184A

      Historical indication and population dosing

      Recovered tables and source-separated snapshots; full clinical revalidation remains pending.

      Existing dose and route snapshots

      RoutePopulationIndicationDoseIntervalDurationAdministrationSource levelNotes
      Source IDH51-EB173CC265077EC42000A71C
      IV infusion
      Source IDH51-9FCD0FB1D593F2A572E99A86
      Adult analgesic infusion
      Source IDH51-6AE2B8FB167593A859896248
      Existing preparation record; use current package insert for indication-specific selection
      Source IDH51-DD104553E629731B542606BB
      Prepare standardized concentration
      Source IDH51-9744A187FB3F9E8B2EA9F0CF
      Not normalized in the preparation record
      Source IDH51-BF35960369E7E1B34EEE1B1F
      See current package insert and professional guidance
      Source IDH51-9D08BCE271F1D3F214354D1B
      Commonly 0.05 to 0.4 mg/kg/hour under protocol
      Source IDH51-ED6377D64DD0933CED389CB1
      Existing GlobalRPh structured preparation snapshot
      Source IDH51-E9BACD2FB7D8411A31CA93A2
      Do not use anesthetic-range dosing without airway-level monitoring.
      Source IDH51-1E08F25D032FA3AF653D11C0
      Source IDH51-1B83621A3FB23A2947E6AB3A
      IV push
      Source IDH51-B3197381BA387440BD3D311B
      Adult induction
      Source IDH51-D4C9DFD509BB4B6E38CBFEEF
      Commonly 1 to 2 mg/kg
      Source IDH51-F774546B7210F3B076159AC8
      Commonly 1 to 2 mg/kg
      Source IDH51-107AD38B052975AC7009C91B
      Patient- and indication-specific
      Source IDH51-FEB5621A329B379A43E8D515
      See current package insert
      Source IDH51-89F12B0376792E6AF04C1414
      Over 30 to 60 seconds
      Source IDH51-EB77A07F5CEC3FB1A0BD0156
      Existing GlobalRPh IV push snapshot
      Source IDH51-6E39F320B0D8C9A046B2EBA5
      Airway/anesthesia protocol only
      Source IDH51-42124A526A0386B618F9E8A3
      Source IDH51-CC71D6B1FB8FD08AD7D4B01C
      IV push
      Source IDH51-5513463E673C01E565FA72C5
      Adult analgesia
      Source IDH51-8CB36A90B74C27A43C783D46
      Commonly 0.1 to 0.3 mg/kg
      Source IDH51-4A9433D970A423D51D0E53DB
      Commonly 0.1 to 0.3 mg/kg
      Source IDH51-C7102426C7E35157DC0DD76F
      Patient- and indication-specific
      Source IDH51-C290F34851127394CE10BAB6
      See current package insert
      Source IDH51-8EFB80CF8843C7884F2AD47F
      Over 10 to 15 minutes rather than rapid push
      Source IDH51-267C21DD66E777D4EBDAC280
      Existing GlobalRPh IV push snapshot
      Source IDH51-0ED5F76570C4ACF12ABF1034
      Protocol-controlled Slower administration reduces psychoperceptual and hemodynamic effects.
      Source IDH51-594D6BBBD442D84DCB72D4DB
      Source IDH51-A039A2F12303E86F45F9DFD7
      Continuous IV infusion
      Source IDH51-372D0A69765E2F5B0A78B733
      Adult analgesia
      Source IDH51-CA7B62D2FD0D33FD81B95FF2
      Existing continuous-infusion record
      Source IDH51-9849C14A608F899C7756A775
      0.05 to 0.1 mg/kg/hour
      Source IDH51-F99E3D436DE39F176E1624AF
      Continuous infusion; titration-specific
      Source IDH51-6C1E56C1AA3DC0993FEC85F5
      Clinical-response dependent
      Source IDH51-DAD1B69F659654438A25DF6F
      Titrate to pain and adverse effects
      Source IDH51-3DE1C1609B34EC5F0A6911F8
      Existing GlobalRPh continuous-infusion snapshot
      Source IDH51-07F7AFBC3B0EC4CA29A4CEC1
      Commonly 0.4 mg/kg/hour in subanesthetic protocols Higher sedation/anesthesia doses require distinct protocols.
      Source IDH51-D828DDEB167BA1A1A8B2BFD4

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      current_label_review_required
      Source IDH51-C41CE13FF098F771C9E730C9
      Summary
      Renal dosing status has not been locally normalized; use the current package insert before ordering or administration.
      Source IDH51-1419A0A163A7DE6D5A57BA5D
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-BC08CD847E146A4A8D8A460F

      Historical Common IV uses

      Recovered v5.1 source content; historical, awaiting current review.

      1. Induction
        Source IDH51-265F11036FF3D6123BF07F98
      2. Procedural sedation
        Source IDH51-BDF81FA6C23A79E64043E774
      3. Subanesthetic analgesia
        Source IDH51-471EA32AE33AB7CC4ED9232D
      4. Selected refractory status asthmaticus or status epilepticus protocols
        Source IDH51-F5149D16132C5F293A79D415

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Hypertension, tachycardia, emergence reactions, hypersalivation, and rare laryngospasm.
        Source IDH51-D28B66EC3D23A965745E70E1
      2. Respiratory depression can occur with rapid/high doses or sedative combinations.
        Source IDH51-5A05D70BF8C95A6753FCD0CF

      Historical Monitoring

      Recovered v5.1 source content; historical, awaiting current review.

      1. Blood pressure, heart rate, oxygenation, and ventilation
        Source IDH51-6ABC6C2581DBB23E3DA6B826
      2. Sedation/dissociation and pain score
        Source IDH51-F5566CC86EDEB3E13C11F497
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      ketamine
      Source IDH51-9B3081E5C434CB3B9D988A8D
      Generic name
      Ketamine
      Source IDH51-DCE7B649AD012DB5E7672FD0
      Brand names
      1. Ketalar
        Source IDH51-EA1ABF77FA8E759F96E89091
      Class
      Sedation, analgesia, and anesthesia
      Source IDH51-34285EEC0E75DC1FB9455BAA
      Subclass
      Dissociative anesthetic and analgesic
      Source IDH51-2E5DC5EC7CD0AEDCF2C8D819
      Summary
      Dissociative anesthetic used by controlled bolus or infusion; concentration, dose, and monitoring differ markedly between analgesia, sedation, and induction.
      Source IDH51-D4EADF67F2DBBBAA9FC29F25
      Populations
      1. Adult
        Source IDH51-048742C86D9D41CB856D8613
      2. Pediatric
        Source IDH51-16CBEBE141C78450C24A3F93
      Evidence tier
      Core reference - verify current label
      Source IDH51-3B22DA3583FD8F83D5A5B344
      High alert
      true
      Source IDH51-A7C8A978E19F4EAD6452D313
      Hazardous
      false
      Source IDH51-B449546579F9611460CE9858
      Status
      Active
      Source IDH51-2C3B5F23698FA15C0E5F1ADF
      Reviewed
      2026-08-29
      Source IDH51-9290B1F441C7C55550F448A4
      Version added
      1.2
      Source IDH51-0E3BC8E6ADA3197155146FAB
      Sources
      LabelUrlKind
      Source IDH51-35E3B900904ADDBAA1F0B19A
      DailyMed label search
      Source IDH51-E89A031E488D4F2C6161A141
      https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Ketamine (opens in a new tab)
      Source IDH51-80177E8FB275831564B67C55
      Primary
      Source IDH51-6528A59260033E9B22FBA15F
      Source IDH51-EECC127952377B2992768434
      GlobalRPh legacy IV dilution monograph
      Source IDH51-A733AB403FBA76391001AA29
      legacy:auto
      Source IDH51-B9C2960C529CF5C81B7C2BE9
      Legacy
      Source IDH51-49BEEB1A1D00F11629BAE95F
      Clinical release verification
      Audit version
      3.4
      Source IDH51-F3C52C1B71C19A6A07BD279D
      Audited on
      2026-08-30
      Source IDH51-FA6041395667F2FE49EB8556
      Level
      amber
      Source IDH51-50A9623CF875DEB466E4B16B
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-CE226896124C3C2B6E8DD3B2
      Exact current label candidate
      false
      Source IDH51-4535C3897C2116457663B53F
      Numeric support ratio
      0
      Source IDH51-78D9310167D979A948A6FF4F
      Reference url count
      1
      Source IDH51-5C406A91BEA066176E991B4B
      Broken reference count
      0
      Source IDH51-004F6CBFEC3555B1B020B5F0
      Point of use confirmation required
      true
      Source IDH51-BB96746150188572C47D8782
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-75E1C4C631DE88A358EF6DCE
      Dailymed search url
      https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Ketamine (opens in a new tab)
      Source IDH51-1EA690770F4CA4BCFBAEDB0B

      Dosing source fields

      Id
      ketamine
      Source IDH51-EB34EE332CB78D4B0ACCEB0A
      Generic name
      Ketamine
      Source IDH51-0EEE547961A57F2E99FCA105
      Coverage status
      direct_official_label_access_plus_local_snapshot
      Source IDH51-D7D0B6FE07EF125A388EAEDB
      Package insert
      Query name
      Ketamine
      Source IDH51-70EBCC94FAB4951026A01FF4
      Product and route must match
      true
      Source IDH51-D5E0E4706505ABCD7D6FC381
      Live current label enabled
      false
      Source IDH51-93E9A41AFAED51A7B062A01E
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-3F0BAD7DF3EDFA2392BCF1ED
      Direct official label access enabled
      true
      Source IDH51-CE235FCC59475A78307E00CD
      Outbound server request required
      false
      Source IDH51-B65F13E955B1478F2E4B62E3
      Local summary status
      not_bundled
      Source IDH51-93BDC54659CD074A748DAC32
      Clinical review
      Locally normalized
      false
      Source IDH51-EFB7E30F74A91D9A242A4A02
      Reviewed
      2026-08-29
      Source IDH51-83264733F1497ED9F012ED53
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-EDBC8023AB07ACCF72EE48A2
      Clinical release verification
      Audit version
      3.4
      Source IDH51-674245E373FAA52A4B50BA97
      Audited on
      2026-08-30
      Source IDH51-CC2B12CD29B3DB18E2E3AAF5
      Level
      amber
      Source IDH51-524544E61233A40D2EE98D46
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-78F4A742A52E9000CB52CC21
      Exact current label candidate
      false
      Source IDH51-434B4412198994A0347B2852
      Numeric support ratio
      0
      Source IDH51-5F85345BE1799931E7B2230F
      Reference url count
      1
      Source IDH51-18BFECE87030F4D31C1684A1
      Broken reference count
      0
      Source IDH51-FCC675996BEC596D80F5EBDA
      Point of use confirmation required
      true
      Source IDH51-2B923B2249EE310181FC8347
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-CE557DE01C70CABF4BF76270
      Dailymed search url
      https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Ketamine (opens in a new tab)
      Source IDH51-7D6A7BCE7462E4FBF6C53051
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      ketamine
      Source IDH51-2B1D9BB4B0112AB8ED8222CD
      Name
      Ketamine
      Source IDH51-7DD1335432DCE2D75FECBEBB
      Brands
      Ketalar
      Source IDH51-7A9AA22C741BE29E25B4ADF0
      Therapeutic class
      Sedation, analgesia, and anesthesia
      Source IDH51-938B0281BB0C052ACBAEE2B4
      Review version
      3.1
      Source IDH51-52274B8417D70CAEAA509A51
      Review date
      2026-08-30
      Source IDH51-6FC0971705882EE22C61F905
      Release status
      structured_record_current_label_not_confirmed
      Source IDH51-D1F31AA5F52803D608C17868
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-CAD5612CE236E26A370ED928
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-C4D06347B64AC2B9573A4B61
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-6B8C6DCBCEA6F4E459BD32FA
      Reconstitution concentration
      Dilute 10, 50, or 100 mg/mL product as needed.
      Source IDH51-BB929C28ADBA8F485D1F5A33
      Maximum or recommended final concentration
      1 to 2 mg/mL
      Source IDH51-327B7D0B5E762ABC9D4798F6
      Appropriate standardized containers
      50 to 250 mL
      Source IDH51-995E749713AE58E23FDC631C
      Adult dosing range
      Prepare standardized concentration Commonly 1 to 2 mg/kg Commonly 0.1 to 0.3 mg/kg 0.05 to 0.1 mg/kg/hour Commonly 1 to 2 mg/kg Commonly 0.1 to 0.3 mg/kg
      Source IDH51-CD71C9BDA5F3A4ECB0992F9C
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-E5349713BBAB814AF36F686F
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-D563BD120BD747D58327E4D7
      Infusion time
      Commonly 0.05 to 0.4 mg/kg/hour under protocol Over 30 to 60 seconds Over 10 to 15 minutes rather than rapid push 0.05 to 0.1 mg/kg/hour
      Source IDH51-A02338622328AAB4C9D96DD2
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-BAEE610B497896006C1BA4D0
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-7CFC521FD348F86C0CB65EEC
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-4F515104026C12652ECC03D0
      Reconstitution concentration
      Primary
      existing_structured_record
      Source IDH51-D65E70624BC3D6F16EC8EB84
      Maximum or recommended final concentration
      Primary
      existing_structured_record
      Source IDH51-51E96DB538B85591BEFC9F2E
      Appropriate standardized containers
      Primary
      existing_structured_record
      Source IDH51-FBDA951FBE3B2201470CC110
      Adult dosing range
      Primary
      existing_structured_record
      Source IDH51-B9FAC71AC207A8098E9D0077
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-D8351EE03ED4F41322E50D70
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-D9BE5FFF614AF67B9071822B
      Infusion time
      Primary
      existing_structured_record
      Source IDH51-08E9E9D2AB688E7C93ACFA71
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-92883EA69E6BB7813FF3FB0F
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-F7C432BAB220D6D6DB6D734C
      Population applicability
      Adult
      Applicability
      supported_or_source_present
      Source IDH51-61CA8E8B6999CE686A1F759C
      Guide generation allowed
      true
      Source IDH51-BC4D0F91860E0C489B093ED2
      Pediatric
      Applicability
      supported_or_source_present
      Source IDH51-CCAC77D99AF2C5E852C07473
      Guide generation allowed
      false
      Source IDH51-99171CE02A6A67E6C71865BB
      Neonatal
      Applicability
      not_established
      Source IDH51-814B9DC8DF758DB87155EF17
      Guide generation allowed
      false
      Source IDH51-9D879FA4EC78548002850A80
      Route presence
      Structured dilution
      true
      Source IDH51-2E84EA4E0FEBE53381DD8198
      Iv push
      true
      Source IDH51-5719FD9E308C8392E434E495
      Continuous infusion
      true
      Source IDH51-1BDBE4EDD2696AB580A5BF31
      Pediatric source
      true
      Source IDH51-055B6B9FAFF22D5916157E7A
      Neonatal source
      false
      Source IDH51-A38D230AA88D295E148E5A9C
      Legacy reference
      Status
      not_available
      Source IDH51-8EBA0C5E2F71B3E4DDDD11A7
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-F6D923AA8E1AC9A4BF53E9F0
      Concentration values detected
      LowHighUnitText
      Source IDH51-3F42B1303DE078B4C98E75E5
      1
      Source IDH51-7932C9EE0139D7127B969103
      2
      Source IDH51-23E58E5FAD618BD790FD1239
      mg
      Source IDH51-7AE624B1F99AE5D7492744BC
      1 to 2 mg/mL
      Source IDH51-3D5898AB1247D75BAF4F9DEB
      Source files
      1. catalog.json
        Source IDH51-D9B3068C61ACDD2748E9878E
      2. dosing.json
        Source IDH51-76EFC6564B7F38468656DEB3
      3. new-in-v1.2.json
        Source IDH51-9C7F90C4B94C759B9DED25CF
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-5546952500AD1EDBDCFDB198
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-9B3081E5C434CB3B9D988A8Dcatalog.json
      /records/140/id
      Historical; current review incomplete
      H51-DCE7B649AD012DB5E7672FD0catalog.json
      /records/140/generic_name
      Historical; current review incomplete
      H51-EA1ABF77FA8E759F96E89091catalog.json
      /records/140/brand_names/0
      Historical; current review incomplete
      H51-34285EEC0E75DC1FB9455BAAcatalog.json
      /records/140/class
      Historical; current review incomplete
      H51-2E5DC5EC7CD0AEDCF2C8D819catalog.json
      /records/140/subclass
      Historical; current review incomplete
      H51-D4EADF67F2DBBBAA9FC29F25catalog.json
      /records/140/summary
      Historical; current review incomplete
      H51-265F11036FF3D6123BF07F98catalog.json
      /records/140/common_uses/0
      Historical; current review incomplete
      H51-BDF81FA6C23A79E64043E774catalog.json
      /records/140/common_uses/1
      Historical; current review incomplete
      H51-471EA32AE33AB7CC4ED9232Dcatalog.json
      /records/140/common_uses/2
      Historical; current review incomplete
      H51-F5149D16132C5F293A79D415catalog.json
      /records/140/common_uses/3
      Historical; current review incomplete
      H51-66905812ED78D44655A1F376catalog.json
      /records/140/preparations/0
      Historical; current review incomplete
      H51-1B9F0D55B72798DFF1242E5Acatalog.json
      /records/140/preparations/0/population
      Historical; current review incomplete
      H51-25E2FB82377AA3C01D503BDCcatalog.json
      /records/140/preparations/0/amount
      Historical; current review incomplete
      H51-E5491931D3130F2178BF48C2catalog.json
      /records/140/preparations/0/reconstitution
      Historical; current review incomplete
      H51-5BAB32C44E2AB1215ADAEA93catalog.json
      /records/140/preparations/0/diluent
      Historical; current review incomplete
      H51-71F99C2894D028D8E10F3AE7catalog.json
      /records/140/preparations/0/final_volume
      Historical; current review incomplete
      H51-EA008783678476A5947947FEcatalog.json
      /records/140/preparations/0/concentration
      Historical; current review incomplete
      H51-44235B626E9EC4F3661C8034catalog.json
      /records/140/preparations/0/rate
      Historical; current review incomplete
      H51-B0A269786A0F0E06DB3E43A6catalog.json
      /records/140/preparations/0/stability
      Historical; current review incomplete
      H51-441B7FB44D909E71ABB19BB9catalog.json
      /records/140/preparations/0/notes
      Historical; current review incomplete
      H51-052C2D19DB771192704366EEcatalog.json
      /records/140/iv_push/0
      Historical; current review incomplete
      H51-6D6401D9F0634FA3B6F17698catalog.json
      /records/140/iv_push/0/population
      Historical; current review incomplete
      H51-7F4C07EEC0C5CAC487591490catalog.json
      /records/140/iv_push/0/dose_scope
      Historical; current review incomplete
      H51-EFFCBB64363C12E826339D19catalog.json
      /records/140/iv_push/0/concentration
      Historical; current review incomplete
      H51-B4E86FD95BD23EC6C9C25B6Fcatalog.json
      /records/140/iv_push/0/rate
      Historical; current review incomplete
      H51-36CD45F5923FE7A08DEB2C2Fcatalog.json
      /records/140/iv_push/0/status
      Historical; current review incomplete
      H51-BD7C39F412ECA9EF010EEE75catalog.json
      /records/140/iv_push/0/notes
      Historical; current review incomplete
      H51-86F603C32A26B14AC78A3621catalog.json
      /records/140/iv_push/1
      Historical; current review incomplete
      H51-7924466E5888CA20C1968A91catalog.json
      /records/140/iv_push/1/population
      Historical; current review incomplete
      H51-B42926E8282D3E310C309830catalog.json
      /records/140/iv_push/1/dose_scope
      Historical; current review incomplete
      H51-A7FE34E750E0AEBF42A666CEcatalog.json
      /records/140/iv_push/1/concentration
      Historical; current review incomplete
      H51-253C1FEC8280B8B5FE993DD7catalog.json
      /records/140/iv_push/1/rate
      Historical; current review incomplete
      H51-B9A7648392E21826C59F932Ecatalog.json
      /records/140/iv_push/1/status
      Historical; current review incomplete
      H51-C490063A8A8ACB595A028B4Fcatalog.json
      /records/140/iv_push/1/notes
      Historical; current review incomplete
      H51-0582F86CC7D9CBE5241B2DC4catalog.json
      /records/140/continuous_infusions/0
      Historical; current review incomplete
      H51-EB41D39D318181F8641DB19Fcatalog.json
      /records/140/continuous_infusions/0/population
      Historical; current review incomplete
      H51-59D9A84783F655895B867371catalog.json
      /records/140/continuous_infusions/0/standard_concentration
      Historical; current review incomplete
      H51-93E3F3B8754ABDE13048058Dcatalog.json
      /records/140/continuous_infusions/0/initial_rate
      Historical; current review incomplete
      H51-34C08F49AB3AC50BA2D24C4Bcatalog.json
      /records/140/continuous_infusions/0/titration
      Historical; current review incomplete
      H51-5BCDE5500BE918024F398590catalog.json
      /records/140/continuous_infusions/0/maximum
      Historical; current review incomplete
      H51-A38A6A340F4D9259C259184Acatalog.json
      /records/140/continuous_infusions/0/notes
      Historical; current review incomplete
      H51-D28B66EC3D23A965745E70E1catalog.json
      /records/140/warnings/0
      Historical; current review incomplete
      H51-5A05D70BF8C95A6753FCD0CFcatalog.json
      /records/140/warnings/1
      Historical; current review incomplete
      H51-6ABC6C2581DBB23E3DA6B826catalog.json
      /records/140/monitoring/0
      Historical; current review incomplete
      H51-F5566CC86EDEB3E13C11F497catalog.json
      /records/140/monitoring/1
      Historical; current review incomplete
      H51-048742C86D9D41CB856D8613catalog.json
      /records/140/populations/0
      Historical; current review incomplete
      H51-16CBEBE141C78450C24A3F93catalog.json
      /records/140/populations/1
      Historical; current review incomplete
      H51-3B22DA3583FD8F83D5A5B344catalog.json
      /records/140/evidence_tier
      Historical; current review incomplete
      H51-A7C8A978E19F4EAD6452D313catalog.json
      /records/140/high_alert
      Historical; current review incomplete
      H51-B449546579F9611460CE9858catalog.json
      /records/140/hazardous
      Historical; current review incomplete
      H51-2C3B5F23698FA15C0E5F1ADFcatalog.json
      /records/140/status
      Historical; current review incomplete
      H51-9290B1F441C7C55550F448A4catalog.json
      /records/140/reviewed
      Historical; current review incomplete
      H51-0E3BC8E6ADA3197155146FABcatalog.json
      /records/140/version_added
      Historical; current review incomplete
      H51-35E3B900904ADDBAA1F0B19Acatalog.json
      /records/140/sources/0
      Historical; current review incomplete
      H51-E89A031E488D4F2C6161A141catalog.json
      /records/140/sources/0/label
      Historical; current review incomplete
      H51-80177E8FB275831564B67C55catalog.json
      /records/140/sources/0/url
      Historical; current review incomplete
      H51-6528A59260033E9B22FBA15Fcatalog.json
      /records/140/sources/0/kind
      Historical; current review incomplete
      H51-EECC127952377B2992768434catalog.json
      /records/140/sources/1
      Historical; current review incomplete
      H51-A733AB403FBA76391001AA29catalog.json
      /records/140/sources/1/label
      Historical; current review incomplete
      H51-B9C2960C529CF5C81B7C2BE9catalog.json
      /records/140/sources/1/url
      Historical; current review incomplete
      H51-49BEEB1A1D00F11629BAE95Fcatalog.json
      /records/140/sources/1/kind
      Historical; current review incomplete
      H51-37C5BC840315BE99DD7D5CDFcatalog.json
      /records/140/legacy_title
      Historical; current review incomplete
      H51-F3C52C1B71C19A6A07BD279Dcatalog.json
      /records/140/clinical_release_verification/audit_version
      Historical; current review incomplete
      H51-FA6041395667F2FE49EB8556catalog.json
      /records/140/clinical_release_verification/audited_on
      Historical; current review incomplete
      H51-50A9623CF875DEB466E4B16Bcatalog.json
      /records/140/clinical_release_verification/level
      Historical; current review incomplete
      H51-CE226896124C3C2B6E8DD3B2catalog.json
      /records/140/clinical_release_verification/release_gate
      Historical; current review incomplete
      H51-4535C3897C2116457663B53Fcatalog.json
      /records/140/clinical_release_verification/exact_current_label_candidate
      Historical; current review incomplete
      H51-938EE1F996F1AA31CCD059D2catalog.json
      /records/140/clinical_release_verification/selected_setid
      Historical; current review incomplete
      H51-D5ECB0FEDDBE01F1305101F2catalog.json
      /records/140/clinical_release_verification/selected_label_title
      Historical; current review incomplete
      H51-78D9310167D979A948A6FF4Fcatalog.json
      /records/140/clinical_release_verification/numeric_support_ratio
      Historical; current review incomplete
      H51-5C406A91BEA066176E991B4Bcatalog.json
      /records/140/clinical_release_verification/reference_url_count
      Historical; current review incomplete
      H51-004F6CBFEC3555B1B020B5F0catalog.json
      /records/140/clinical_release_verification/broken_reference_count
      Historical; current review incomplete
      H51-BB96746150188572C47D8782catalog.json
      /records/140/clinical_release_verification/point_of_use_confirmation_required
      Historical; current review incomplete
      H51-75E1C4C631DE88A358EF6DCEcatalog.json
      /records/140/clinical_release_verification/note
      Historical; current review incomplete
      H51-1EA690770F4CA4BCFBAEDB0Bcatalog.json
      /records/140/clinical_release_verification/dailymed_search_url
      Historical; current review incomplete
      H51-EB34EE332CB78D4B0ACCEB0Adosing.json
      /records/140/id
      Historical; current review incomplete
      H51-0EEE547961A57F2E99FCA105dosing.json
      /records/140/generic_name
      Historical; current review incomplete
      H51-D7D0B6FE07EF125A388EAEDBdosing.json
      /records/140/coverage_status
      Historical; current review incomplete
      H51-70EBCC94FAB4951026A01FF4dosing.json
      /records/140/package_insert/query_name
      Historical; current review incomplete
      H51-11F8D31A61963BDB53EFE0A8dosing.json
      /records/140/package_insert/preferred_setid
      Historical; current review incomplete
      H51-D5E0E4706505ABCD7D6FC381dosing.json
      /records/140/package_insert/product_and_route_must_match
      Historical; current review incomplete
      H51-93E9A41AFAED51A7B062A01Edosing.json
      /records/140/package_insert/live_current_label_enabled
      Historical; current review incomplete
      H51-3F0BAD7DF3EDFA2392BCF1EDdosing.json
      /records/140/package_insert/source_priority
      Historical; current review incomplete
      H51-CE235FCC59475A78307E00CDdosing.json
      /records/140/package_insert/direct_official_label_access_enabled
      Historical; current review incomplete
      H51-B65F13E955B1478F2E4B62E3dosing.json
      /records/140/package_insert/outbound_server_request_required
      Historical; current review incomplete
      H51-93BDC54659CD074A748DAC32dosing.json
      /records/140/package_insert/local_summary_status
      Historical; current review incomplete
      H51-C41CE13FF098F771C9E730C9dosing.json
      /records/140/renal/classification
      Historical; current review incomplete
      H51-1419A0A163A7DE6D5A57BA5Ddosing.json
      /records/140/renal/summary
      Historical; current review incomplete
      H51-BC08CD847E146A4A8D8A460Fdosing.json
      /records/140/renal/method_note
      Historical; current review incomplete
      H51-EB173CC265077EC42000A71Cdosing.json
      /records/140/existing_route_snapshots/0
      Historical; current review incomplete
      H51-9FCD0FB1D593F2A572E99A86dosing.json
      /records/140/existing_route_snapshots/0/route
      Historical; current review incomplete
      H51-6AE2B8FB167593A859896248dosing.json
      /records/140/existing_route_snapshots/0/population
      Historical; current review incomplete
      H51-DD104553E629731B542606BBdosing.json
      /records/140/existing_route_snapshots/0/indication
      Historical; current review incomplete
      H51-9744A187FB3F9E8B2EA9F0CFdosing.json
      /records/140/existing_route_snapshots/0/dose
      Historical; current review incomplete
      H51-BF35960369E7E1B34EEE1B1Fdosing.json
      /records/140/existing_route_snapshots/0/interval
      Historical; current review incomplete
      H51-9D08BCE271F1D3F214354D1Bdosing.json
      /records/140/existing_route_snapshots/0/duration
      Historical; current review incomplete
      H51-ED6377D64DD0933CED389CB1dosing.json
      /records/140/existing_route_snapshots/0/administration
      Historical; current review incomplete
      H51-E9BACD2FB7D8411A31CA93A2dosing.json
      /records/140/existing_route_snapshots/0/source_level
      Historical; current review incomplete
      H51-1E08F25D032FA3AF653D11C0dosing.json
      /records/140/existing_route_snapshots/0/notes
      Historical; current review incomplete
      H51-1B83621A3FB23A2947E6AB3Adosing.json
      /records/140/existing_route_snapshots/1
      Historical; current review incomplete
      H51-B3197381BA387440BD3D311Bdosing.json
      /records/140/existing_route_snapshots/1/route
      Historical; current review incomplete
      H51-D4C9DFD509BB4B6E38CBFEEFdosing.json
      /records/140/existing_route_snapshots/1/population
      Historical; current review incomplete
      H51-F774546B7210F3B076159AC8dosing.json
      /records/140/existing_route_snapshots/1/indication
      Historical; current review incomplete
      H51-107AD38B052975AC7009C91Bdosing.json
      /records/140/existing_route_snapshots/1/dose
      Historical; current review incomplete
      H51-FEB5621A329B379A43E8D515dosing.json
      /records/140/existing_route_snapshots/1/interval
      Historical; current review incomplete
      H51-89F12B0376792E6AF04C1414dosing.json
      /records/140/existing_route_snapshots/1/duration
      Historical; current review incomplete
      H51-EB77A07F5CEC3FB1A0BD0156dosing.json
      /records/140/existing_route_snapshots/1/administration
      Historical; current review incomplete
      H51-6E39F320B0D8C9A046B2EBA5dosing.json
      /records/140/existing_route_snapshots/1/source_level
      Historical; current review incomplete
      H51-42124A526A0386B618F9E8A3dosing.json
      /records/140/existing_route_snapshots/1/notes
      Historical; current review incomplete
      H51-CC71D6B1FB8FD08AD7D4B01Cdosing.json
      /records/140/existing_route_snapshots/2
      Historical; current review incomplete
      H51-5513463E673C01E565FA72C5dosing.json
      /records/140/existing_route_snapshots/2/route
      Historical; current review incomplete
      H51-8CB36A90B74C27A43C783D46dosing.json
      /records/140/existing_route_snapshots/2/population
      Historical; current review incomplete
      H51-4A9433D970A423D51D0E53DBdosing.json
      /records/140/existing_route_snapshots/2/indication
      Historical; current review incomplete
      H51-C7102426C7E35157DC0DD76Fdosing.json
      /records/140/existing_route_snapshots/2/dose
      Historical; current review incomplete
      H51-C290F34851127394CE10BAB6dosing.json
      /records/140/existing_route_snapshots/2/interval
      Historical; current review incomplete
      H51-8EFB80CF8843C7884F2AD47Fdosing.json
      /records/140/existing_route_snapshots/2/duration
      Historical; current review incomplete
      H51-267C21DD66E777D4EBDAC280dosing.json
      /records/140/existing_route_snapshots/2/administration
      Historical; current review incomplete
      H51-0ED5F76570C4ACF12ABF1034dosing.json
      /records/140/existing_route_snapshots/2/source_level
      Historical; current review incomplete
      H51-594D6BBBD442D84DCB72D4DBdosing.json
      /records/140/existing_route_snapshots/2/notes
      Historical; current review incomplete
      H51-A039A2F12303E86F45F9DFD7dosing.json
      /records/140/existing_route_snapshots/3
      Historical; current review incomplete
      H51-372D0A69765E2F5B0A78B733dosing.json
      /records/140/existing_route_snapshots/3/route
      Historical; current review incomplete
      H51-CA7B62D2FD0D33FD81B95FF2dosing.json
      /records/140/existing_route_snapshots/3/population
      Historical; current review incomplete
      H51-9849C14A608F899C7756A775dosing.json
      /records/140/existing_route_snapshots/3/indication
      Historical; current review incomplete
      H51-F99E3D436DE39F176E1624AFdosing.json
      /records/140/existing_route_snapshots/3/dose
      Historical; current review incomplete
      H51-6C1E56C1AA3DC0993FEC85F5dosing.json
      /records/140/existing_route_snapshots/3/interval
      Historical; current review incomplete
      H51-DAD1B69F659654438A25DF6Fdosing.json
      /records/140/existing_route_snapshots/3/duration
      Historical; current review incomplete
      H51-3DE1C1609B34EC5F0A6911F8dosing.json
      /records/140/existing_route_snapshots/3/administration
      Historical; current review incomplete
      H51-07F7AFBC3B0EC4CA29A4CEC1dosing.json
      /records/140/existing_route_snapshots/3/source_level
      Historical; current review incomplete
      H51-D828DDEB167BA1A1A8B2BFD4dosing.json
      /records/140/existing_route_snapshots/3/notes
      Historical; current review incomplete
      H51-EFB7E30F74A91D9A242A4A02dosing.json
      /records/140/clinical_review/locally_normalized
      Historical; current review incomplete
      H51-83264733F1497ED9F012ED53dosing.json
      /records/140/clinical_review/reviewed
      Historical; current review incomplete
      H51-EDBC8023AB07ACCF72EE48A2dosing.json
      /records/140/clinical_review/status
      Historical; current review incomplete
      H51-674245E373FAA52A4B50BA97dosing.json
      /records/140/clinical_release_verification/audit_version
      Historical; current review incomplete
      H51-CC2B12CD29B3DB18E2E3AAF5dosing.json
      /records/140/clinical_release_verification/audited_on
      Historical; current review incomplete
      H51-524544E61233A40D2EE98D46dosing.json
      /records/140/clinical_release_verification/level
      Historical; current review incomplete
      H51-78F4A742A52E9000CB52CC21dosing.json
      /records/140/clinical_release_verification/release_gate
      Historical; current review incomplete
      H51-434B4412198994A0347B2852dosing.json
      /records/140/clinical_release_verification/exact_current_label_candidate
      Historical; current review incomplete
      H51-92E2D1C6CA3306B84EFFAE7Bdosing.json
      /records/140/clinical_release_verification/selected_setid
      Historical; current review incomplete
      H51-24E303293FE971E1103B9ACCdosing.json
      /records/140/clinical_release_verification/selected_label_title
      Historical; current review incomplete
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