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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Medication reference

Cangrelor

Monograph awaiting updateThis monograph will be updated in the future.

Jump to a section
Selected DailyMed label (opens in a new tab)

No original site article was mapped to this record. The available historical structured fields and official-source links are retained.

Historical first look: uses, mechanism, dosing context, and administration

Recovered v5.1 source content; historical, awaiting current review.

Id
cangrelor
Source IDH51-7FC603701A0FCE07BCF69D4E
Generic name
Cangrelor
Source IDH51-DFDB5CBA025866E1E8DF8FB5
Class
Anticoagulation and hemostasis
Source IDH51-B170B7A67D1245FF3B78B9CD
Subclass
IV P2Y12 platelet inhibitor
Source IDH51-431BC0D8A6FF6AC173BF34D9
Primary uses
  1. Adjunct to PCI in selected patients
    Source IDH51-E4D6B0766B51B8C62CAFC0B6
Mechanism
Reversibly blocks platelet P2Y12 receptors and rapidly inhibits ADP-mediated platelet activation.
Source IDH51-A0F1B669F9A030B1AEA7E6AE
Mechanism level
drug_specific
Source IDH51-C39726C66671073DFC82F804
Basic dosing orientation
Adult PCI | Existing preparation record; use current package insert for indication-specific selection | 50 mg vial | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult PCI | 30 mcg/kg | 30 mcg/kg | Patient- and indication-specific | See current package insert | IV push
Source IDH51-C668C30B2BEE5C837D661D8E
Administration orientation
Bolus then 4 mcg/kg/min infusion; Rapid IV bolus before infusion; 200 mcg/mL final solution; Rapid IV bolus before infusion
Source IDH51-1166BC9D5B484DE8824988A8
Renal and population orientation
Separate renal reference: Open Renal Dosing Master (opens in a new tab)Renal dosing status has not been locally normalized; use the current package insert before ordering or administration.
Source IDH51-7525FBAC8AF50CFFCBB36288
Key safety orientation
  1. Serious bleeding.
    Source IDH51-C96874D317ABC43A91770C8E
  2. Oral antiplatelet transition errors can create a gap in platelet inhibition.
    Source IDH51-E1BF28C7D8203FC26FF17C4B
Coverage path
structured_local_snapshot
Source IDH51-63D94E5D3608222C91A3073A
Coverage path label
Structured GlobalRPh route snapshot
Source IDH51-5EF2EABD8210F71815D0CC2D
Review note
First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
Source IDH51-8F861FB0BB18F9568F04AE36
Search text
Cangrelor Anticoagulation and hemostasis IV P2Y12 platelet inhibitor Adjunct to PCI in selected patients Reversibly blocks platelet P2Y12 receptors and rapidly inhibits ADP-mediated platelet activation. Adult PCI | Existing preparation record; use current package insert for indication-specific selection | 50 mg vial | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult PCI | 30 mcg/kg | 30 mcg/kg | Patient- and indication-specific | See current package insert | IV push Bolus then 4 mcg/kg/min infusion; Rapid IV bolus before infusion; 200 mcg/mL final solution; Rapid IV bolus before infusion Renal dosing status has not been locally normalized; use the current package insert before ordering or administration. Serious bleeding. Oral antiplatelet transition errors can create a gap in platelet inhibition. Structured GlobalRPh route snapshot KENGREAL KENGREAL (cangrelor) injection, powder, lyophilized, for solution DailyMed label snapshot dosage administration dosage forms strengths mechanism
Source IDH51-D4E932AB4308900A2904ABE7
Official access mode
direct_label
Source IDH51-CA1539D361500959FCD95D67
Official search query
Cangrelor
Source IDH51-FE8B5A2FBB7598CE5F692A95
Official access reason
Very-high-confidence exact IV product label selected during the v5.1 build-time review. Open the current full DailyMed monograph and verify the stocked product before use.
Source IDH51-789AD2D4A9C67C5EF7562B98
Label snapshot available
true
Source IDH51-38548A393DF88C194E7D1B8D
Label snapshot setid
88b434fa-8891-4fd5-9d86-7ea64667c08f
Source IDH51-DCD7661CC7FFF1996B0F8BE1
Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • A retrieved source document is available; clinical reconciliation and a second-source claim map remain incomplete
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
current_label_review_required
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      • Source kind
        label_snapshot
        Local pointer
        /mechanism_summary
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Concise GlobalRPh summary reviewed against the selected DailyMed label clinical-pharmacology or microbiology content.
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.

      No separate structured rows were bundled for dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical dilution and intermittent infusion preparation

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationAmountReconstitutionDiluentFinal volumeConcentrationRateStabilityNotes
      Source IDH51-512D8F4331467C36DCEAC5DA
      Adult PCI
      Source IDH51-1CB329FC4304C6E5AA3B802F
      		50 mg vial
      Source IDH51-829E1C5DEF60AACF2C66F025
      		Reconstitute with 5 mL Sterile Water for Injection to 10 mg/mL, then withdraw 5 mL.
      Source IDH51-1949708A6088227F36F2F60B
      		NS or D5W
      Source IDH51-5F0B31AD470E68A364493D86
      		250 mL
      Source IDH51-E42AA1D5D42E92774F1D95E0
      		200 mcg/mL
      Source IDH51-E9A59DF9DA33A6C7F0480ABB
      		Bolus then 4 mcg/kg/min infusion
      Source IDH51-51787E0F9A8CFCCEB475B903
      		Use the shorter of current product labeling, validated stability data, and the applicable USP <797> sterility-based BUD ceiling.
      Source IDH51-61F4FDCAD915BAA359144B06
      		Plan transition to an oral P2Y12 inhibitor using drug-specific timing.
      Source IDH51-6F9EE751B4E7EC4FEFD9E5D8

      Historical DailyMed label snapshot

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      cangrelor
      Source IDH51-95C12B99E461DC9474EDA9BD
      Catalog name
      Cangrelor
      Source IDH51-E09844BC9358FFCFE67B19BD
      Selection status
      accepted_high_confidence
      Source IDH51-1774D4EF8C9F4A750952BF95
      Confidence
      very_high
      Source IDH51-9D68647E7C9AD240F9B7FC07
      Match path
      search_to_exact_label
      Source IDH51-1789F475B718C1E2C783A0AF
      Brand name
      KENGREAL
      Source IDH51-E590A442A1F29C39FF9520FC
      Label title
      KENGREAL (cangrelor) injection, powder, lyophilized, for solution
      Source IDH51-D10E054B16AD1B5B20FFF9E1
      Setid
      88b434fa-8891-4fd5-9d86-7ea64667c08f
      Source IDH51-67E969C9DCD84DDE279207FA
      Route
      Intravenous bolus followed by continuous infusion
      Source IDH51-22E54D6EC8CD2B95B34CA126
      Dosage form
      Lyophilized powder for reconstitution and dilution
      Source IDH51-818208171F322874E7F21FB3
      Dosage administration summary
      1. Administer a 30 mcg/kg intravenous bolus before PCI, followed immediately by a 4 mcg/kg/min infusion.
        Source IDH51-36A4CCAC32B0C60073398AEE
      2. Continue the infusion for at least 2 hours or for the duration of PCI, whichever is longer, unless the current label and clinical plan direct otherwise.
        Source IDH51-CB9C8D20BA3F4A0DC60BD82C
      3. Use a dedicated intravenous line after reconstitution and dilution, and follow the label when transitioning to an oral P2Y12 inhibitor.
        Source IDH51-B3FA0BABEF98D158E6BA3966
      Dosage forms strengths
      1. 50 mg cangrelor lyophilized powder in a single-dose vial
        Source IDH51-BB1E7DE1A4D739772F3B89FA
      Mechanism summary
      Cangrelor selectively and reversibly blocks platelet P2Y12 receptors, preventing ADP-mediated platelet activation and aggregation.
      Source IDH51-637135BAC1F5C77FCA95FD0B
      Scope note
      Selected KENGREAL PCI label. The transition to oral antiplatelet therapy is timing-specific and must follow the current label.
      Source IDH51-40E52942FA8EED31E6714D58
      Reviewed on
      2026-08-31
      Source IDH51-7778F9079FE26D95F43962E3
      Mechanism source
      Concise GlobalRPh summary reviewed against the selected DailyMed label clinical-pharmacology or microbiology content.
      Source IDH51-F40BE65ADC9469D5EEE43B84
      Source sections
      1. Dosage and Administration
        Source IDH51-C6A0C9A4DC58D22B25B6EA5B
      2. Dosage Forms and Strengths
        Source IDH51-9707122BD6A9F923200FE34E
      3. Clinical Pharmacology or Microbiology as applicable
        Source IDH51-AE3D4FDBF940AE17AA2B834F
      Retrieval method
      Manual build-time review of the current DailyMed full prescribing information for the selected Set ID; no live server retrieval is required during page use.
      Source IDH51-2CD7430B951A9CE5FAD34CE9
      Label status
      current
      Source IDH51-051B7C5FA96D2B5917595E86
      Disclaimer
      Verify the exact formulation, strength, manufacturer, NDC, route, current label revision, patient-specific order, institutional policy, and monitoring before use.
      Source IDH51-0AC3494C0364224DD2DD0B2B

      Historical IV-push guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationDose scopeConcentrationRateStatus
      Source IDH51-5AA43F585F946CD5B4D9C0A6
      Adult PCI
      Source IDH51-2076F6609D8ADD70B322DBB6
      		30 mcg/kg
      Source IDH51-634CFA7C374548C3CB22690B
      		200 mcg/mL final solution
      Source IDH51-5EA4163539700176630805F3
      		Rapid IV bolus before infusion
      Source IDH51-A77D157625092E7CB05CEEB0
      		PCI protocol only
      Source IDH51-24BBA069973D4571C2E917CF

      Historical continuous-infusion guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationStandard concentrationInitial rateTitrationMaximumNotes
      Source IDH51-591410701FAA0B9405C32629
      Adult PCI
      Source IDH51-66ADE2BEB3A4EB84FFC389F2
      		50 mg/250 mL (200 mcg/mL)
      Source IDH51-4AE6079E6588B6B87B088185
      		4 mcg/kg/min after bolus
      Source IDH51-D5106DEF0AA6B4275FF1B629
      		Fixed during PCI; duration per label/protocol
      Source IDH51-D2422AB9B5B02CCCD9EB7C75
      		4 mcg/kg/min
      Source IDH51-BA3C9B8239D56EB8859F88D7
      		Transition timing differs for clopidogrel, prasugrel, and ticagrelor.
      Source IDH51-1905A5CB565BB9981DAA0980

      Historical indication and population dosing

      Recovered tables and source-separated snapshots; full clinical revalidation remains pending.

      Existing dose and route snapshots

      RoutePopulationIndicationDoseIntervalDurationAdministrationSource levelNotes
      Source IDH51-1850BCA0A2EF2200C9F6B5A7
      IV infusion
      Source IDH51-AB344D385AC4B513AB58FDD5
      		Adult PCI
      Source IDH51-023C6CAAE6808ABA5997B516
      		Existing preparation record; use current package insert for indication-specific selection
      Source IDH51-D1779DA2A9DB809606715592
      		50 mg vial
      Source IDH51-821157756509D4759972A6D7
      		Not normalized in the preparation record
      Source IDH51-40EF4F3D3A5432A98F717F87
      		See current package insert and professional guidance
      Source IDH51-034A7CE1D625C521529FC2FF
      		Bolus then 4 mcg/kg/min infusion
      Source IDH51-220FBCE1D0269B4B45992ED1
      		Existing GlobalRPh structured preparation snapshot
      Source IDH51-73887B5E74DFDA7E363B3563
      		Plan transition to an oral P2Y12 inhibitor using drug-specific timing.
      Source IDH51-6D4819CCE4D4C11246A88941
      Source IDH51-C0FA71FCA3E1B84B3E3E17BD
      IV push
      Source IDH51-78A6F790CAE38188257DDC11
      		Adult PCI
      Source IDH51-CFBB94647F7486E3D66D9D28
      		30 mcg/kg
      Source IDH51-22F3694426436A0FA5854AF5
      		30 mcg/kg
      Source IDH51-6B5D297A9DEC8E3B9DA3C220
      		Patient- and indication-specific
      Source IDH51-4BCFB4534A3A07E8C34B6FC9
      		See current package insert
      Source IDH51-4FBBB81334A4844CC6BA130A
      		Rapid IV bolus before infusion
      Source IDH51-804AD8AE59B9A103E699B768
      		Existing GlobalRPh IV push snapshot
      Source IDH51-8A8A4658434A6F1B894E51F1
      		PCI protocol only
      Source IDH51-BD3104BCE3069DBD39924D7A
      Source IDH51-3360AE8C33F489D67FBE9066
      Continuous IV infusion
      Source IDH51-21034B3E9C6340A413854D84
      		Adult PCI
      Source IDH51-CE0680043FC28A8A21120044
      		Existing continuous-infusion record
      Source IDH51-D84F5AC3B7CBEAF2B7B104DE
      		4 mcg/kg/min after bolus
      Source IDH51-073A6813EC87595F038F039A
      		Continuous infusion; titration-specific
      Source IDH51-51A888FBF53C81E920A92CD4
      		Clinical-response dependent
      Source IDH51-FB2619DBEFC7C3C113ED8912
      		Fixed during PCI; duration per label/protocol
      Source IDH51-64ECA5718AFC06AC197211CF
      		Existing GlobalRPh continuous-infusion snapshot
      Source IDH51-EC54F670911666C3DBBA5935
      		4 mcg/kg/min Transition timing differs for clopidogrel, prasugrel, and ticagrelor.
      Source IDH51-3320AC7C1333562D247CB0F4

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      current_label_review_required
      Source IDH51-E51786AE351E7E932C914069
      Summary
      Renal dosing status has not been locally normalized; use the current package insert before ordering or administration.
      Source IDH51-5A77540C7FB381D7D76E604F
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-67F6840019D5A5B4D91DBB54

      Historical Common IV uses

      Recovered v5.1 source content; historical, awaiting current review.

      1. Adjunct to PCI in selected patients
        Source IDH51-9F0E082BBACD3FBE3C9739A6

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Serious bleeding.
        Source IDH51-6EB8A6A7D8B033956D1DCCB9
      2. Oral antiplatelet transition errors can create a gap in platelet inhibition.
        Source IDH51-1BB4CDB3920623790AE0A974

      Historical Monitoring

      Recovered v5.1 source content; historical, awaiting current review.

      1. Bleeding
        Source IDH51-DA3DAAA09E564266FBD873D0
      2. Procedure status
        Source IDH51-AD32CD8B0A7282756C4EC851
      3. Oral P2Y12 transition timing
        Source IDH51-40860FDA09A70B20AFEC6C45
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      cangrelor
      Source IDH51-E81700E6FAD0EEDE5344F167
      Generic name
      Cangrelor
      Source IDH51-22D94E1EC5CEA009B712A754
      Brand names
      1. Kengreal
        Source IDH51-1574D13F9B419029267EE5A9
      Class
      Anticoagulation and hemostasis
      Source IDH51-2999898D1965AAE604146799
      Subclass
      IV P2Y12 platelet inhibitor
      Source IDH51-1A971A02991BE17D0379E301
      Summary
      Rapid-onset, rapidly reversible antiplatelet agent requiring reconstitution, dilution, bolus, continuous infusion, and planned oral transition.
      Source IDH51-DD8B8F634E8A7B1BF675F8DE
      Populations
      1. Adult
        Source IDH51-8FAA9B7E949B3BDBFCF5F207
      Evidence tier
      Core reference - verify current label
      Source IDH51-BCD013995052CFB5462E402D
      High alert
      true
      Source IDH51-D36D8F8E5354589096E73B0E
      Hazardous
      false
      Source IDH51-8B674D00387B51EEA7813FBB
      Status
      Active
      Source IDH51-255C86014C8639D34079A9CB
      Reviewed
      2026-08-29
      Source IDH51-6408DBF35315841550104766
      Version added
      1.2
      Source IDH51-E5F53420B45D15EB8B7E4DF6
      Sources
      LabelUrlKind
      Source IDH51-86D49175FF07FAB6487103E5
      DailyMed label search
      Source IDH51-685E47DDC3B61B387697B187
      		https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Cangrelor (opens in a new tab)
      Source IDH51-9FC92BEC1C03552869E64316
      		Primary
      Source IDH51-CEE2BEA5AC33E23977C82C55
      Source IDH51-E5310A5063C5BDE1805B8D93
      GlobalRPh legacy IV dilution monograph
      Source IDH51-C85B11496C6B81776CE89156
      		legacy:auto
      Source IDH51-225579C926B0E76743E83A42
      		Legacy
      Source IDH51-340A94524987C3A9D8D367A4
      Clinical release verification
      Audit version
      3.4
      Source IDH51-7C7A1853AAA97829C3925698
      Audited on
      2026-08-30
      Source IDH51-4380D935F8E8D062785FD6ED
      Level
      amber
      Source IDH51-0623BF4D8825C681251387CB
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-9EF634A07C906ED5750E89A9
      Exact current label candidate
      false
      Source IDH51-9E98BE3705F883077D2D7915
      Numeric support ratio
      0
      Source IDH51-0A47FB69E65041086860C80B
      Reference url count
      1
      Source IDH51-AB0462D0DE18AD1E91CC3F8B
      Broken reference count
      0
      Source IDH51-6C2756B2A89CBA1FEF26559E
      Point of use confirmation required
      true
      Source IDH51-F3DECBBA4572A7161F9346DE
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-4207AEC38A6EB32100F14337
      Version updated
      5.1
      Source IDH51-11C97CB8D7EFBBD2805F3A89

      Dosing source fields

      Id
      cangrelor
      Source IDH51-2E780A60227314551098A7B4
      Generic name
      Cangrelor
      Source IDH51-C91F717D4B48F97EDB75ADB3
      Coverage status
      direct_official_label_access_plus_local_snapshot
      Source IDH51-26D750AF15C54016CDF5740D
      Package insert
      Query name
      Cangrelor
      Source IDH51-C485D9AFBD9D3470D1F91ABB
      Product and route must match
      true
      Source IDH51-E182FAEACDB68C6CAF1168EE
      Live current label enabled
      false
      Source IDH51-22A62EB49818E813BCEC1B9F
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-038ECD9F3E56DD73DF98CBE1
      Direct official label access enabled
      true
      Source IDH51-DBDF3D02F6F1903FE4F61912
      Outbound server request required
      false
      Source IDH51-CBEE798F8AE1A944E06AF8E9
      Local summary status
      not_bundled
      Source IDH51-3AA2650EC59432D3E797FF93
      Clinical review
      Locally normalized
      false
      Source IDH51-41C67263BAE4BB3FC96B89E0
      Reviewed
      2026-08-29
      Source IDH51-2F852AD884F41943BB54DDAB
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-8E8C4A5D0BA5A026244043A0
      Clinical release verification
      Audit version
      3.4
      Source IDH51-B2A12D9555FE70EE2A07CB61
      Audited on
      2026-08-30
      Source IDH51-0BF82A7C4DAD9139957871A8
      Level
      amber
      Source IDH51-A04FADBE0BED751B176F3E3C
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-7811E48C22942D3BF65DEF43
      Exact current label candidate
      false
      Source IDH51-CA7DA2E0EF420B81EB39DED2
      Numeric support ratio
      0
      Source IDH51-DF7AF73F06605115B6822AD4
      Reference url count
      1
      Source IDH51-5106D50D31690CF2B4FE1A85
      Broken reference count
      0
      Source IDH51-E880BF8DAAB1CE7D49E49829
      Point of use confirmation required
      true
      Source IDH51-1AF35617B758659A75DB9BF2
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-872C48830EA40F4F87435DE7
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      cangrelor
      Source IDH51-4142EA5CB95279896967ECFB
      Name
      Cangrelor
      Source IDH51-4D54F31F0814FA54DA6E7CE9
      Brands
      Kengreal
      Source IDH51-A1A105F96F23E587F2914594
      Therapeutic class
      Anticoagulation and hemostasis
      Source IDH51-F4B674AFE8759AA8C6D719CA
      Review version
      3.1
      Source IDH51-AB550818814C3CA6CEAC570D
      Review date
      2026-08-30
      Source IDH51-F4289CA8D75EFFC7307636EA
      Release status
      structured_record_current_label_not_confirmed
      Source IDH51-1CC2CB0A6A453FFFAF43C95A
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-A9B9544DCD0B4213C437117E
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-5EB8A0CAAA6FA1F4C653D288
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-7384DEEE77E683A3468D384A
      Reconstitution concentration
      Reconstitute with 5 mL Sterile Water for Injection to 10 mg/mL, then withdraw 5 mL.
      Source IDH51-3E363992B8C64C4EC944E5AA
      Maximum or recommended final concentration
      50 mg/250 mL (200 mcg/mL)
      Source IDH51-9C2E3A92C23E7AB434A597B6
      Appropriate standardized containers
      250 mL
      Source IDH51-2735945CC06B8B8DB0F94BDD
      Adult dosing range
      50 mg vial 30 mcg/kg 4 mcg/kg/min after bolus 30 mcg/kg
      Source IDH51-D8156793386E290821CE1B59
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-9A76D31A84EC9C79A7E4BC03
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-735E1AFCCCA64B2F2F07689D
      Infusion time
      Bolus then 4 mcg/kg/min infusion Rapid IV bolus before infusion 4 mcg/kg/min after bolus
      Source IDH51-8D6030D63027949F87797E3E
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-9533C8AE7D4DED580C419161
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-2A64B3C2569D1CD458408FC1
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-B8F7198853272EAD895D844E
      Reconstitution concentration
      Primary
      existing_structured_record
      Source IDH51-A64B4DBCC4D71828AF76D692
      Maximum or recommended final concentration
      Primary
      existing_structured_record
      Source IDH51-1D7E709CD83F7F2982F564F1
      Appropriate standardized containers
      Primary
      existing_structured_record
      Source IDH51-B60020FD5CBFE45EA37B9CFB
      Adult dosing range
      Primary
      existing_structured_record
      Source IDH51-B2A6202DBF5B6A30DA7F618F
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-F6FCC14A9ABAF9E7666B7C38
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-2155FECF5FBD969307F8D0F8
      Infusion time
      Primary
      existing_structured_record
      Source IDH51-4B59160AF911B1E61EEA7AAD
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-E3CD4008E1E276D329657A97
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-3C96AD63F4E9EF6093D5CD75
      Population applicability
      Adult
      Applicability
      supported_or_source_present
      Source IDH51-0D6F67CD132DF926D9E109B5
      Guide generation allowed
      true
      Source IDH51-8FA8E72A9A6580C4E856EED4
      Pediatric
      Applicability
      not_established
      Source IDH51-FD3588D19C16599A0D15CA9B
      Guide generation allowed
      false
      Source IDH51-032F67923DEBCFEC0E4B8BF2
      Neonatal
      Applicability
      not_established
      Source IDH51-22730AB7D360E6EB676AD5A4
      Guide generation allowed
      false
      Source IDH51-33E710AA4933A3A37219DAB9
      Route presence
      Structured dilution
      true
      Source IDH51-738E9A6560F646BA2AC9C4C8
      Iv push
      true
      Source IDH51-D3284D58D67D7A73C3C4F900
      Continuous infusion
      true
      Source IDH51-B05DF92EA201E61AD0050B4E
      Pediatric source
      false
      Source IDH51-17EB31D1AEE321777517FF07
      Neonatal source
      false
      Source IDH51-29F07AE3C8F155497295A347
      Legacy reference
      Status
      not_available
      Source IDH51-D5C114D71DE4F92ABA7058DF
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-23CDDB1BB1B98F7E65AE72D0
      Concentration values detected
      HighUnitText
      Source IDH51-E202B3D83F47BD3653F139C9
      200
      Source IDH51-D128A0BA950D38C6B5FB805C
      		mcg
      Source IDH51-BA79F393AC9738A535EECE26
      		200 mcg/mL
      Source IDH51-3497D366D34262E98258F2B5
      Source files
      1. catalog.json
        Source IDH51-F49AF51C338C9CCE04AFBD0F
      2. dosing.json
        Source IDH51-005CB96B1D186B38E1A41D79
      3. new-in-v1.2.json
        Source IDH51-EE22E6300964A001D3F289DC
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-83E327DE1FEDEF9D85BFA8D8
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-E81700E6FAD0EEDE5344F167catalog.json
      /records/39/id      		Historical; current review incomplete
      H51-22D94E1EC5CEA009B712A754catalog.json
      /records/39/generic_name      		Historical; current review incomplete
      H51-1574D13F9B419029267EE5A9catalog.json
      /records/39/brand_names/0      		Historical; current review incomplete
      H51-2999898D1965AAE604146799catalog.json
      /records/39/class      		Historical; current review incomplete
      H51-1A971A02991BE17D0379E301catalog.json
      /records/39/subclass      		Historical; current review incomplete
      H51-DD8B8F634E8A7B1BF675F8DEcatalog.json
      /records/39/summary      		Historical; current review incomplete
      H51-9F0E082BBACD3FBE3C9739A6catalog.json
      /records/39/common_uses/0      		Historical; current review incomplete
      H51-512D8F4331467C36DCEAC5DAcatalog.json
      /records/39/preparations/0      		Historical; current review incomplete
      H51-1CB329FC4304C6E5AA3B802Fcatalog.json
      /records/39/preparations/0/population      		Historical; current review incomplete
      H51-829E1C5DEF60AACF2C66F025catalog.json
      /records/39/preparations/0/amount      		Historical; current review incomplete
      H51-1949708A6088227F36F2F60Bcatalog.json
      /records/39/preparations/0/reconstitution      		Historical; current review incomplete
      H51-5F0B31AD470E68A364493D86catalog.json
      /records/39/preparations/0/diluent      		Historical; current review incomplete
      H51-E42AA1D5D42E92774F1D95E0catalog.json
      /records/39/preparations/0/final_volume      		Historical; current review incomplete
      H51-E9A59DF9DA33A6C7F0480ABBcatalog.json
      /records/39/preparations/0/concentration      		Historical; current review incomplete
      H51-51787E0F9A8CFCCEB475B903catalog.json
      /records/39/preparations/0/rate      		Historical; current review incomplete
      H51-61F4FDCAD915BAA359144B06catalog.json
      /records/39/preparations/0/stability      		Historical; current review incomplete
      H51-6F9EE751B4E7EC4FEFD9E5D8catalog.json
      /records/39/preparations/0/notes      		Historical; current review incomplete
      H51-5AA43F585F946CD5B4D9C0A6catalog.json
      /records/39/iv_push/0      		Historical; current review incomplete
      H51-2076F6609D8ADD70B322DBB6catalog.json
      /records/39/iv_push/0/population      		Historical; current review incomplete
      H51-634CFA7C374548C3CB22690Bcatalog.json
      /records/39/iv_push/0/dose_scope      		Historical; current review incomplete
      H51-5EA4163539700176630805F3catalog.json
      /records/39/iv_push/0/concentration      		Historical; current review incomplete
      H51-A77D157625092E7CB05CEEB0catalog.json
      /records/39/iv_push/0/rate      		Historical; current review incomplete
      H51-24BBA069973D4571C2E917CFcatalog.json
      /records/39/iv_push/0/status      		Historical; current review incomplete
      H51-467E4E30C127A6A7C702744Ccatalog.json
      /records/39/iv_push/0/notes      		Historical; current review incomplete
      H51-591410701FAA0B9405C32629catalog.json
      /records/39/continuous_infusions/0      		Historical; current review incomplete
      H51-66ADE2BEB3A4EB84FFC389F2catalog.json
      /records/39/continuous_infusions/0/population      		Historical; current review incomplete
      H51-4AE6079E6588B6B87B088185catalog.json
      /records/39/continuous_infusions/0/standard_concentration      		Historical; current review incomplete
      H51-D5106DEF0AA6B4275FF1B629catalog.json
      /records/39/continuous_infusions/0/initial_rate      		Historical; current review incomplete
      H51-D2422AB9B5B02CCCD9EB7C75catalog.json
      /records/39/continuous_infusions/0/titration      		Historical; current review incomplete
      H51-BA3C9B8239D56EB8859F88D7catalog.json
      /records/39/continuous_infusions/0/maximum      		Historical; current review incomplete
      H51-1905A5CB565BB9981DAA0980catalog.json
      /records/39/continuous_infusions/0/notes      		Historical; current review incomplete
      H51-6EB8A6A7D8B033956D1DCCB9catalog.json
      /records/39/warnings/0      		Historical; current review incomplete
      H51-1BB4CDB3920623790AE0A974catalog.json
      /records/39/warnings/1      		Historical; current review incomplete
      H51-DA3DAAA09E564266FBD873D0catalog.json
      /records/39/monitoring/0      		Historical; current review incomplete
      H51-AD32CD8B0A7282756C4EC851catalog.json
      /records/39/monitoring/1      		Historical; current review incomplete
      H51-40860FDA09A70B20AFEC6C45catalog.json
      /records/39/monitoring/2      		Historical; current review incomplete
      H51-8FAA9B7E949B3BDBFCF5F207catalog.json
      /records/39/populations/0      		Historical; current review incomplete
      H51-BCD013995052CFB5462E402Dcatalog.json
      /records/39/evidence_tier      		Historical; current review incomplete
      H51-D36D8F8E5354589096E73B0Ecatalog.json
      /records/39/high_alert      		Historical; current review incomplete
      H51-8B674D00387B51EEA7813FBBcatalog.json
      /records/39/hazardous      		Historical; current review incomplete
      H51-255C86014C8639D34079A9CBcatalog.json
      /records/39/status      		Historical; current review incomplete
      H51-6408DBF35315841550104766catalog.json
      /records/39/reviewed      		Historical; current review incomplete
      H51-E5F53420B45D15EB8B7E4DF6catalog.json
      /records/39/version_added      		Historical; current review incomplete
      H51-86D49175FF07FAB6487103E5catalog.json
      /records/39/sources/0      		Historical; current review incomplete
      H51-685E47DDC3B61B387697B187catalog.json
      /records/39/sources/0/label      		Historical; current review incomplete
      H51-9FC92BEC1C03552869E64316catalog.json
      /records/39/sources/0/url      		Historical; current review incomplete
      H51-CEE2BEA5AC33E23977C82C55catalog.json
      /records/39/sources/0/kind      		Historical; current review incomplete
      H51-E5310A5063C5BDE1805B8D93catalog.json
      /records/39/sources/1      		Historical; current review incomplete
      H51-C85B11496C6B81776CE89156catalog.json
      /records/39/sources/1/label      		Historical; current review incomplete
      H51-225579C926B0E76743E83A42catalog.json
      /records/39/sources/1/url      		Historical; current review incomplete
      H51-340A94524987C3A9D8D367A4catalog.json
      /records/39/sources/1/kind      		Historical; current review incomplete
      H51-3C0B513706BB4BDF035FE2DDcatalog.json
      /records/39/legacy_title      		Historical; current review incomplete
      H51-7C7A1853AAA97829C3925698catalog.json
      /records/39/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-4380D935F8E8D062785FD6EDcatalog.json
      /records/39/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-0623BF4D8825C681251387CBcatalog.json
      /records/39/clinical_release_verification/level      		Historical; current review incomplete
      H51-9EF634A07C906ED5750E89A9catalog.json
      /records/39/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-9E98BE3705F883077D2D7915catalog.json
      /records/39/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-B0A23B3B9417C381C55D95D1catalog.json
      /records/39/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-6646EA667D34BCA1B6831EC4catalog.json
      /records/39/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-0A47FB69E65041086860C80Bcatalog.json
      /records/39/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-AB0462D0DE18AD1E91CC3F8Bcatalog.json
      /records/39/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-6C2756B2A89CBA1FEF26559Ecatalog.json
      /records/39/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-F3DECBBA4572A7161F9346DEcatalog.json
      /records/39/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-4207AEC38A6EB32100F14337catalog.json
      /records/39/clinical_release_verification/note      		Historical; current review incomplete
      H51-4498D38CA1080E662E3A2C0Ccatalog.json
      /records/39/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-11C97CB8D7EFBBD2805F3A89catalog.json
      /records/39/version_updated      		Historical; current review incomplete
      H51-95C12B99E461DC9474EDA9BDdailymed-label-snapshots-v5.1.json
      /records/9/id      		Historical; current review incomplete
      H51-E09844BC9358FFCFE67B19BDdailymed-label-snapshots-v5.1.json
      /records/9/catalog_name      		Historical; current review incomplete
      H51-1774D4EF8C9F4A750952BF95dailymed-label-snapshots-v5.1.json
      /records/9/selection_status      		Historical; current review incomplete
      H51-9D68647E7C9AD240F9B7FC07dailymed-label-snapshots-v5.1.json
      /records/9/confidence      		Historical; current review incomplete
      H51-1789F475B718C1E2C783A0AFdailymed-label-snapshots-v5.1.json
      /records/9/match_path      		Historical; current review incomplete
      H51-E590A442A1F29C39FF9520FCdailymed-label-snapshots-v5.1.json
      /records/9/brand_name      		Historical; current review incomplete
      H51-D10E054B16AD1B5B20FFF9E1dailymed-label-snapshots-v5.1.json
      /records/9/label_title      		Historical; current review incomplete
      H51-67E969C9DCD84DDE279207FAdailymed-label-snapshots-v5.1.json
      /records/9/setid      		Historical; current review incomplete
      H51-22E54D6EC8CD2B95B34CA126dailymed-label-snapshots-v5.1.json
      /records/9/route      		Historical; current review incomplete
      H51-818208171F322874E7F21FB3dailymed-label-snapshots-v5.1.json
      /records/9/dosage_form      		Historical; current review incomplete
      H51-36A4CCAC32B0C60073398AEEdailymed-label-snapshots-v5.1.json
      /records/9/dosage_administration_summary/0      		Historical; current review incomplete
      H51-CB9C8D20BA3F4A0DC60BD82Cdailymed-label-snapshots-v5.1.json
      /records/9/dosage_administration_summary/1      		Historical; current review incomplete
      H51-B3FA0BABEF98D158E6BA3966dailymed-label-snapshots-v5.1.json
      /records/9/dosage_administration_summary/2      		Historical; current review incomplete
      H51-BB1E7DE1A4D739772F3B89FAdailymed-label-snapshots-v5.1.json
      /records/9/dosage_forms_strengths/0      		Historical; current review incomplete
      H51-637135BAC1F5C77FCA95FD0Bdailymed-label-snapshots-v5.1.json
      /records/9/mechanism_summary      		Historical; current review incomplete
      H51-40E52942FA8EED31E6714D58dailymed-label-snapshots-v5.1.json
      /records/9/scope_note      		Historical; current review incomplete
      H51-8863F3A5D1D0A7FA2C27A5F5dailymed-label-snapshots-v5.1.json
      /records/9/labeler      		Historical; current review incomplete
      H51-83BC4A33C47E6E35BA44AC45dailymed-label-snapshots-v5.1.json
      /records/9/official_label_url      		Historical; current review incomplete
      H51-7778F9079FE26D95F43962E3dailymed-label-snapshots-v5.1.json
      /records/9/reviewed_on      		Historical; current review incomplete
      H51-F40BE65ADC9469D5EEE43B84dailymed-label-snapshots-v5.1.json
      /records/9/mechanism_source      		Historical; current review incomplete
      H51-C6A0C9A4DC58D22B25B6EA5Bdailymed-label-snapshots-v5.1.json
      /records/9/source_sections/0      		Historical; current review incomplete
      H51-9707122BD6A9F923200FE34Edailymed-label-snapshots-v5.1.json
      /records/9/source_sections/1      		Historical; current review incomplete
      H51-AE3D4FDBF940AE17AA2B834Fdailymed-label-snapshots-v5.1.json
      /records/9/source_sections/2      		Historical; current review incomplete
      H51-2CD7430B951A9CE5FAD34CE9dailymed-label-snapshots-v5.1.json
      /records/9/retrieval_method      		Historical; current review incomplete
      H51-051B7C5FA96D2B5917595E86dailymed-label-snapshots-v5.1.json
      /records/9/label_status      		Historical; current review incomplete
      H51-0AC3494C0364224DD2DD0B2Bdailymed-label-snapshots-v5.1.json
      /records/9/disclaimer      		Historical; current review incomplete
      H51-2E780A60227314551098A7B4dosing.json
      /records/39/id      		Historical; current review incomplete
      H51-C91F717D4B48F97EDB75ADB3dosing.json
      /records/39/generic_name      		Historical; current review incomplete
      H51-26D750AF15C54016CDF5740Ddosing.json
      /records/39/coverage_status      		Historical; current review incomplete
      H51-C485D9AFBD9D3470D1F91ABBdosing.json
      /records/39/package_insert/query_name      		Historical; current review incomplete
      H51-9A01AD668973CCCF9E374A7Edosing.json
      /records/39/package_insert/preferred_setid      		Historical; current review incomplete
      H51-E182FAEACDB68C6CAF1168EEdosing.json
      /records/39/package_insert/product_and_route_must_match      		Historical; current review incomplete
      H51-22A62EB49818E813BCEC1B9Fdosing.json
      /records/39/package_insert/live_current_label_enabled      		Historical; current review incomplete
      H51-038ECD9F3E56DD73DF98CBE1dosing.json
      /records/39/package_insert/source_priority      		Historical; current review incomplete
      H51-DBDF3D02F6F1903FE4F61912dosing.json
      /records/39/package_insert/direct_official_label_access_enabled      		Historical; current review incomplete
      H51-CBEE798F8AE1A944E06AF8E9dosing.json
      /records/39/package_insert/outbound_server_request_required      		Historical; current review incomplete
      H51-3AA2650EC59432D3E797FF93dosing.json
      /records/39/package_insert/local_summary_status      		Historical; current review incomplete
      H51-E51786AE351E7E932C914069dosing.json
      /records/39/renal/classification      		Historical; current review incomplete
      H51-5A77540C7FB381D7D76E604Fdosing.json
      /records/39/renal/summary      		Historical; current review incomplete
      H51-67F6840019D5A5B4D91DBB54dosing.json
      /records/39/renal/method_note      		Historical; current review incomplete
      H51-1850BCA0A2EF2200C9F6B5A7dosing.json
      /records/39/existing_route_snapshots/0      		Historical; current review incomplete
      H51-AB344D385AC4B513AB58FDD5dosing.json
      /records/39/existing_route_snapshots/0/route      		Historical; current review incomplete
      H51-023C6CAAE6808ABA5997B516dosing.json
      /records/39/existing_route_snapshots/0/population      		Historical; current review incomplete
      H51-D1779DA2A9DB809606715592dosing.json
      /records/39/existing_route_snapshots/0/indication      		Historical; current review incomplete
      H51-821157756509D4759972A6D7dosing.json
      /records/39/existing_route_snapshots/0/dose      		Historical; current review incomplete
      H51-40EF4F3D3A5432A98F717F87dosing.json
      /records/39/existing_route_snapshots/0/interval      		Historical; current review incomplete
      H51-034A7CE1D625C521529FC2FFdosing.json
      /records/39/existing_route_snapshots/0/duration      		Historical; current review incomplete
      H51-220FBCE1D0269B4B45992ED1dosing.json
      /records/39/existing_route_snapshots/0/administration      		Historical; current review incomplete
      H51-73887B5E74DFDA7E363B3563dosing.json
      /records/39/existing_route_snapshots/0/source_level      		Historical; current review incomplete
      H51-6D4819CCE4D4C11246A88941dosing.json
      /records/39/existing_route_snapshots/0/notes      		Historical; current review incomplete
      H51-C0FA71FCA3E1B84B3E3E17BDdosing.json
      /records/39/existing_route_snapshots/1      		Historical; current review incomplete
      H51-78A6F790CAE38188257DDC11dosing.json
      /records/39/existing_route_snapshots/1/route      		Historical; current review incomplete
      H51-CFBB94647F7486E3D66D9D28dosing.json
      /records/39/existing_route_snapshots/1/population      		Historical; current review incomplete
      H51-22F3694426436A0FA5854AF5dosing.json
      /records/39/existing_route_snapshots/1/indication      		Historical; current review incomplete
      H51-6B5D297A9DEC8E3B9DA3C220dosing.json
      /records/39/existing_route_snapshots/1/dose      		Historical; current review incomplete
      H51-4BCFB4534A3A07E8C34B6FC9dosing.json
      /records/39/existing_route_snapshots/1/interval      		Historical; current review incomplete
      H51-4FBBB81334A4844CC6BA130Adosing.json
      /records/39/existing_route_snapshots/1/duration      		Historical; current review incomplete
      H51-804AD8AE59B9A103E699B768dosing.json
      /records/39/existing_route_snapshots/1/administration      		Historical; current review incomplete
      H51-8A8A4658434A6F1B894E51F1dosing.json
      /records/39/existing_route_snapshots/1/source_level      		Historical; current review incomplete
      H51-BD3104BCE3069DBD39924D7Adosing.json
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      H51-3360AE8C33F489D67FBE9066dosing.json
      /records/39/existing_route_snapshots/2      		Historical; current review incomplete
      H51-21034B3E9C6340A413854D84dosing.json
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      H51-CE0680043FC28A8A21120044dosing.json
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      H51-D84F5AC3B7CBEAF2B7B104DEdosing.json
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      H51-51A888FBF53C81E920A92CD4dosing.json
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      H51-FB2619DBEFC7C3C113ED8912dosing.json
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      H51-64ECA5718AFC06AC197211CFdosing.json
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      H51-3320AC7C1333562D247CB0F4dosing.json
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      H51-41C67263BAE4BB3FC96B89E0dosing.json
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      H51-B2A12D9555FE70EE2A07CB61dosing.json
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      H51-0BF82A7C4DAD9139957871A8dosing.json
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      H51-A04FADBE0BED751B176F3E3Cdosing.json
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      H51-87B79E123ADF6C67D1647E77dosing.json
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      H51-E880BF8DAAB1CE7D49E49829dosing.json
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      H51-E873EAFAFF88BEB2C5F6DD2Adosing.json
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      H51-7FC603701A0FCE07BCF69D4Efirst-look-v5.1.json
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      /39/clinical_release_note      		Historical; current review incomplete
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