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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Medication reference

Brivaracetam

Monograph awaiting updateThis monograph will be updated in the future.

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Selected DailyMed label (opens in a new tab)

Historical source. Current clinical review is incomplete. This monograph will be updated in the future.

Brivaracetam (briviact ®) (opens in a new tab)Original source URL: https://globalrph.com/dilution/brivaracetam-briviact/ | Retrieved 2026-11-04

Source dates, location and integrity

This historical article is separate from the reviewed claim cards. Product formulations and source dates may differ.

Original source URL
https://globalrph.com/dilution/brivaracetam-briviact/ (opens in a new tab)
Source date
Not established in the retrieved source
Retrieved
2026-11-04T19:46:23.588223+00:00
Source location
div.post-content
Packaged content SHA-256
1d65173ef0159c56c5b824d751657fa1d4762aab0b7b1c154129f3fc522f8a78
Original response SHA-256
524839b53133ef3def412b9d77a07be39ef40575fa47a672e7a4eea4089132e1
Source body SHA-256
d40647a150c0d6a4a51863e638b77649200974d9fc99fec175c81617afa20ac9

BRIVIACT ® (brivaracetam) injection
[ Usual Diluents ] [ Standard Dilution ] [ Storage and Stability ]
DESCRIPTION CLINICAL PHARMACOLOGY INDICATIONS AND USAGE
CONTRAINDICATIONS PRECAUTIONS ADVERSE REACTIONS
DOSAGE AND ADMINISTRATION HOW SUPPLIED WARNINGS
PRESCRIBING HIGHLIGHTS: Please see package insert for additional information and possible updates to ensure safe and effective use of this medication. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. Please read the disclaimer carefully BEFORE accessing or using this site. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.

Drug UPDATES: [Drug information / PDF]
PACKAGE INSERT -Dosing: Click (+) next to Dosage and Administration section (drug info link)

Usual Diluents Return to article top

NS, D5W, LR

Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate] Return to article top

[Prescribed dose ]
[25-100mg] [10-50 ml] [2 to 15 minutes]
May also be given undiluted. Dilution above allows for the use of
a pvc bag and pump to control the infusion e.g. 50mg/50ml @10 ml/hr.

Hepatic Impairment: For all stages of hepatic impairment, the recommended starting dosage is 25 mg twice daily; maximum dosage is 75 mg twice daily.

BRIVIACT injection may be used when oral administration is temporarily not feasible. BRIVIACT injection should be administered at the same dosage and same frequency as BRIVIACT tablets and oral solution. The clinical study experience with BRIVIACT injection is limited to 4 consecutive days of treatment.

BRIVIACT injection is for single dose only.

Stability data:
Stability
Refrigerated		 Stability
Room Temp.		 Reconstituted
Vial/Powder		 Notes
Room temp only. Do not freeze. Solution: The diluted solution should not be stored for more than 4 hours at room temperature and may be stored in polyvinyl chloride (PVC) bags BRIVIACT injection is for single dose only. Discard any unused portion of the BRIVIACT injection vial contents.

WARNINGS Return to article top

See warnings and precautions below.

DESCRIPTION Return to article top

Description:
The chemical name of BRIVIACT (brivaracetam) is (2S)-2-[(4R)-2-oxo-4-propyltetrahydro-1H-pyrrol-1-yl] butanamide.
Initial U.S. Approval: 2016

CLINICAL PHARMACOLOGY: Return to article top

Mechanism of Action:
The precise mechanism by which BRIVIACT exerts its anticonvulsant activity is not known. Brivaracetam displays a high and selective affinity for synaptic vesicle protein 2A (SV2A) in the brain, which may contribute to the anticonvulsant effect.

INDICATIONS AND USAGE Return to article top

BRIVIACT is indicated as adjunctive therapy in the treatment of partial-onset seizures in patients 16 years of age and older with epilepsy.

CONTRAINDICATIONS Return to article top

Contraindications::
Hypersensitivity to brivaracetam or any of the inactive ingredients in BRIVIACT.

PRECAUTIONS Return to article top

WARNINGS AND PRECAUTIONS:

Suicidal Behavior and Ideation: Monitor patients for suicidal behavior and ideation. (5.1)

Neurological Adverse Reactions: Monitor for somnolence and fatigue, and advise patients not to drive or operate machinery until they have gained sufficient experience on BRIVIACT. (5.2)

Psychiatric Adverse Reactions: Behavioral reactions including psychotic symptoms, irritability, depression, aggressive behavior, and anxiety; monitor patients for symptoms. (5.3)

Hypersensitivity: Bronchospasm and Angioedema: Advise patients to seek immediate medical care. Discontinue and do not restart BRIVIACT if hypersensitivity occurs. (5.4)

Withdrawal of Antiepileptic Drugs: BRIVIACT should be gradually withdrawn. (5.5)

ADVERSE REACTIONS Return to article top

ADVERSE REACTIONS:

Most common adverse reactions (at least 5% for BRIVIACT and at least 2% more frequently than placebo) are somnolence/sedation, dizziness, fatigue, and nausea/vomiting. (6.1)

To report SUSPECTED ADVERSE REACTIONS, contact UCB, Inc. at 1-844-599-2273 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

See PACKAGE INSERT for PATIENT COUNSELING INFORMATION and Medication Guide.

DOSAGE AND ADMINISTRATION Return to article top

DOSAGE AND ADMINISTRATION: The recommended starting dosage is 50 mg twice daily. Based on individual patient tolerability and therapeutic response, the dosage may be adjusted down to 25 mg twice daily (50 mg per day) or up to 100 mg twice daily (200 mg per day). (2.1)
BRIVIACT injection may be used when oral administration is temporarily not feasible.
Hepatic Impairment: For all stages of hepatic impairment, the recommended starting dosage is 25 mg twice daily; maximum dosage is 75 mg twice daily.

2.1 Dosage Information

When initiating treatment, gradual dose escalation is not required. The recommended starting dosage is 50 mg twice daily (100 mg per day). Based on individual patient tolerability and therapeutic response, the dosage may be adjusted down to 25 mg twice daily (50 mg per day) or up to 100 mg twice daily (200 mg per day)

BRIVIACT injection may be used when oral administration is temporarily not feasible. BRIVIACT injection should be administered at the same dosage and same frequency as BRIVIACT tablets and oral solution.

The clinical study experience with BRIVIACT injection is limited to 4 consecutive days of treatment.

2.3 Preparation and Administration Instructions for BRIVIACT Injection

BRIVIACT injection is for intravenous use only.

Preparation

BRIVIACT injection can be administered intravenously without further dilution or may be mixed with diluents listed below.

Diluents
0.9% Sodium Chloride injection, USP
Lactated Ringer's injection
5% Dextrose injection, USP

Administration

BRIVIACT injection should be administered intravenously over 2 to 15 minutes.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Product with particulate matter or discoloration should not be used. BRIVIACT injection is for single dose only.

Storage and Stability

The diluted solution should not be stored for more than 4 hours at room temperature and may be stored in polyvinyl chloride (PVC) bags. Discard any unused portion of the BRIVIACT injection vial contents.

2.4 Discontinuation of BRIVIACT

Avoid abrupt withdrawal from BRIVIACT in order to minimize the risk of increased seizure frequency and status epilepticus [see Warnings and Precautions (5.5) and Clinical Studies (14)].

2.5 Patients with Hepatic Impairment

For all stages of hepatic impairment, the recommended starting dosage is 25 mg twice daily (50 mg per day) and the recommended maximum dosage is 75 mg twice daily (150 mg per day) [see Use in Specific Populations (8.7) and Clinical Pharmacology (12.3)].

2.6 Co-administration with Rifampin

Increase the BRIVIACT dosage in patients on concomitant rifampin by up to 100% (i.e., double the dosage)

HOW SUPPLIED Return to article top

DOSAGE FORMS AND STRENGTHS:

Tablets: 10 mg, 25 mg, 50 mg, 75 mg, and 100 mg (3)
Oral solution: 10 mg/mL (3)
Injection: 50 mg/5 mL single-dose vial (3)

Storage and Stability Return to article top

Store at 25°C (77°F); excursions permitted between 15°C to 30°C (59°F to 86°F). See USP Controlled Room Temperature. Do not freeze BRIVIACT injection or oral solution.

Discard any unused BRIVIACT oral solution remaining after 5 months of first opening the bottle.

BRIVIACT injection vials are single-dose only

Open this historical article on its own

Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • A retrieved source document is available; clinical reconciliation and a second-source claim map remain incomplete
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
current_label_review_required
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      • Source kind
        label_snapshot
        Local pointer
        /mechanism_summary
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Concise GlobalRPh summary reviewed against the selected DailyMed label clinical-pharmacology or microbiology content.
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.
      Historical first look: uses, mechanism, dosing context, and administration

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      brivaracetam
      Source IDH51-FD19508ED88759CE7CE96EFC
      Generic name
      Brivaracetam
      Source IDH51-15FD0F7059F06E7EA31DB24B
      Class
      Neurology and anticonvulsants
      Source IDH51-C809C7278FA15DC841BE9A40
      Subclass
      SV2A anticonvulsant
      Source IDH51-F60FFDF4B30B3E8ED5902071
      Primary uses
      1. Partial-onset seizure treatment when oral administration is temporarily not feasible
        Source IDH51-70B9321D65F915C0FF26A1BC
      Mechanism
      Binds synaptic vesicle protein 2A and modulates neurotransmitter release.
      Source IDH51-8AF39CDB201251305D718454
      Mechanism level
      drug_specific
      Source IDH51-CDA039A9DB917C0CF7DA6937
      Basic dosing orientation
      Adult | Existing preparation record; use current package insert for indication-specific selection | Same total daily dose and frequency as oral regimen | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult | Prescribed dose | Prescribed dose | Patient- and indication-specific | See current package insert | IV push
      Source IDH51-5DF5B0664AF99E493C020C98
      Administration orientation
      IV injection over 2 to 15 minutes or infusion per label; Over 2 to 15 minutes; 10 mg/mL; Over 2 to 15 minutes
      Source IDH51-D9FB034F69C7D412D880E724
      Renal and population orientation
      Separate renal reference: Open Renal Dosing Master (opens in a new tab)Renal dosing status has not been locally normalized; use the current package insert before ordering or administration.
      Source IDH51-CFD065D98AF4EEBA775C90AC
      Key safety orientation
      1. Somnolence, dizziness, fatigue, and psychiatric adverse reactions.
        Source IDH51-BDD1D2C11BE6AD364AFEFFFE
      Coverage path
      structured_local_snapshot
      Source IDH51-B9CDFE9C936D6B95ECBF3064
      Coverage path label
      Structured GlobalRPh route snapshot
      Source IDH51-ED7243A7150846F84A749F84
      Legacy title
      Brivaracetam (Briviact)
      Source IDH51-3A43E6D2579BE2FB4888E3DD
      Review note
      First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
      Source IDH51-A1D2BDA2DFD0F61F2B04165E
      Search text
      Brivaracetam Neurology and anticonvulsants SV2A anticonvulsant Partial-onset seizure treatment when oral administration is temporarily not feasible Binds synaptic vesicle protein 2A and modulates neurotransmitter release. Adult | Existing preparation record; use current package insert for indication-specific selection | Same total daily dose and frequency as oral regimen | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult | Prescribed dose | Prescribed dose | Patient- and indication-specific | See current package insert | IV push IV injection over 2 to 15 minutes or infusion per label; Over 2 to 15 minutes; 10 mg/mL; Over 2 to 15 minutes Renal dosing status has not been locally normalized; use the current package insert before ordering or administration. Somnolence, dizziness, fatigue, and psychiatric adverse reactions. Structured GlobalRPh route snapshot BRIVIACT BRIVIACT (brivaracetam) injection, solution DailyMed label snapshot dosage administration dosage forms strengths mechanism
      Source IDH51-2016070E837A39A50434A79F
      Official access mode
      direct_label
      Source IDH51-1B0962EF6FA9205512C616C4
      Official search query
      Brivaracetam
      Source IDH51-FEB8D2555DCDB3A4AC1F8473
      Official access reason
      Very-high-confidence exact IV product label selected during the v5.1 build-time review. Open the current full DailyMed monograph and verify the stocked product before use.
      Source IDH51-DE0E545447D9B5F6C95EABBC
      Label snapshot available
      true
      Source IDH51-436079D9E52A2F0784C96E25
      Label snapshot setid
      3cf2f439-0e97-443e-8e33-25ecef616f6c
      Source IDH51-7D37F72C0D83B87F2F64AB55

      No separate structured rows were bundled for continuous infusion, dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical dilution and intermittent infusion preparation

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationAmountReconstitutionDiluentFinal volumeConcentrationRateStabilityNotes
      Source IDH51-8449C72150D4D13B4C4F767D
      Adult
      Source IDH51-7ED97EB03D2665FA8014B0B9
      		Same total daily dose and frequency as oral regimen
      Source IDH51-D45DE54C7ADCBE88060B07B9
      		No reconstitution required.
      Source IDH51-19FB8AD00228E64046AF8271
      		May be given undiluted or diluted in NS, D5W, or LR
      Source IDH51-1F59C491812E905E48771DA6
      		Syringe or small bag
      Source IDH51-F9D9FDDE4B841199448E533F
      		10 mg/mL undiluted
      Source IDH51-C03605E858017ACDFDCBBBA6
      		IV injection over 2 to 15 minutes or infusion per label
      Source IDH51-4B91DC5C8B53BE7A1D66E965
      		Use the shorter of current product labeling, validated stability data, and the applicable USP <797> sterility-based BUD ceiling.
      Source IDH51-6988E04ACFC34DAC30168763
      		Use current label for pediatric age eligibility.
      Source IDH51-09BB193A8BAD7066E26E9E85

      Historical DailyMed label snapshot

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      brivaracetam
      Source IDH51-DBB11503657BD9831C4A0736
      Catalog name
      Brivaracetam
      Source IDH51-0E8D4832772D8255A3F678A3
      Selection status
      accepted_high_confidence
      Source IDH51-34CA0471829F996055A11EB6
      Confidence
      very_high
      Source IDH51-8CDC4C44541311E3231F47DC
      Match path
      search_to_exact_label
      Source IDH51-657E71E1428C08A3A9DC3326
      Brand name
      BRIVIACT
      Source IDH51-91055FBEF294EA4BF00A2676
      Label title
      BRIVIACT (brivaracetam) injection, solution
      Source IDH51-9C7BC5299752156989965D2A
      Setid
      3cf2f439-0e97-443e-8e33-25ecef616f6c
      Source IDH51-C662AEF837A85189FBD5E328
      Route
      Intravenous injection or infusion
      Source IDH51-C8C8AF1D70C6A2B849F8BB7B
      Dosage form
      Ready-to-use injection solution
      Source IDH51-A7156840E4C0CA56749310CD
      Dosage administration summary
      1. Use the intravenous formulation when oral administration is temporarily not feasible; use the same total daily dose and frequency as the oral regimen.
        Source IDH51-E9C9953E9BB0769ACD5F1042
      2. Administer intravenously over 2 to 15 minutes. The product may be administered undiluted or after dilution with a label-supported compatible solution.
        Source IDH51-1DFCA956F33BC057430BAA22
      3. Inspect the solution before use and discard any unused portion of the single-dose vial.
        Source IDH51-178CB9661ECD731847D7E7F3
      Dosage forms strengths
      1. 10 mg/mL injection in a 50 mg/5 mL single-dose vial
        Source IDH51-A7AC145A7BF3409AD80B15B1
      Mechanism summary
      Brivaracetam binds with high affinity to synaptic vesicle protein 2A (SV2A), which is believed to contribute to its antiseizure activity.
      Source IDH51-8EFBB8A8547D9319FEBA319B
      Scope note
      The selected BRIVIACT label contains oral and intravenous presentations. This snapshot is limited to the intravenous product.
      Source IDH51-5739834AFF75D6CF856109A3
      Reviewed on
      2026-08-31
      Source IDH51-69F67B3011637650499D33CA
      Mechanism source
      Concise GlobalRPh summary reviewed against the selected DailyMed label clinical-pharmacology or microbiology content.
      Source IDH51-5C7DA0FBB35D4ECF1DF15957
      Source sections
      1. Dosage and Administration
        Source IDH51-751A177FB0A1EE2AEF3F3BE2
      2. Dosage Forms and Strengths
        Source IDH51-220D14A875C9865EFDEFE564
      3. Clinical Pharmacology or Microbiology as applicable
        Source IDH51-FD67033D74168D1BDC31821B
      Retrieval method
      Manual build-time review of the current DailyMed full prescribing information for the selected Set ID; no live server retrieval is required during page use.
      Source IDH51-16A3FDBC9AE564636C6C2808
      Label status
      current
      Source IDH51-FFD5D74D2D509F510E228242
      Disclaimer
      Verify the exact formulation, strength, manufacturer, NDC, route, current label revision, patient-specific order, institutional policy, and monitoring before use.
      Source IDH51-DDA3629128A8E618A090555D

      Historical IV-push guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationDose scopeConcentrationRateStatus
      Source IDH51-ABCC83997A29F558CF8A0F99
      Adult
      Source IDH51-581FAEF2901265835245046F
      		Prescribed dose
      Source IDH51-F30B2F05EADCA9CC17BCCBF0
      		10 mg/mL
      Source IDH51-FE3DE50682417846789B07F7
      		Over 2 to 15 minutes
      Source IDH51-1161CCC41248BF394DCB950B
      		Label-standard IV injection
      Source IDH51-F856621C4DECFCFFB13F4D0D

      Historical indication and population dosing

      Recovered tables and source-separated snapshots; full clinical revalidation remains pending.

      Existing dose and route snapshots

      RoutePopulationIndicationDoseIntervalDurationAdministrationSource levelNotes
      Source IDH51-A28B077E4E9B5E2A37AA19F8
      IV infusion
      Source IDH51-8D319EC8C0233CE00FAD3784
      		Adult
      Source IDH51-FCC526A990AD29F10FBA308F
      		Existing preparation record; use current package insert for indication-specific selection
      Source IDH51-4DF55135EC2F307A24C0B671
      		Same total daily dose and frequency as oral regimen
      Source IDH51-005C51DE6E454B4089EF7221
      		Not normalized in the preparation record
      Source IDH51-4C8B6BD7949F7AE88533DA9F
      		See current package insert and professional guidance
      Source IDH51-30D1804F1FC0672054F6DBCC
      		IV injection over 2 to 15 minutes or infusion per label
      Source IDH51-9CA2A9B6D2F087035EF7D90B
      		Existing GlobalRPh structured preparation snapshot
      Source IDH51-CAB936D5DB6FFAF5AD47B2A9
      		Use current label for pediatric age eligibility.
      Source IDH51-08BD72550D32EF694674CF37
      Source IDH51-6A099F3C3D3F2091F4C16ABC
      IV push
      Source IDH51-9A98688D28D2B7A28220EA6D
      		Adult
      Source IDH51-BFB1793D9E0F6C6530B88DA7
      		Prescribed dose
      Source IDH51-C1A8C8EFC3D446DA84537008
      		Prescribed dose
      Source IDH51-56857255427385FB5759AD9C
      		Patient- and indication-specific
      Source IDH51-E1A0992574E77363CF6A1E25
      		See current package insert
      Source IDH51-BBDEB92BB81C4DBDEE7E59EC
      		Over 2 to 15 minutes
      Source IDH51-FE530F2DD863C9A2FD3CDF98
      		Existing GlobalRPh IV push snapshot
      Source IDH51-7EFA500B50593DF9E23BC778
      		Label-standard IV injection
      Source IDH51-C0BFF0FF8C6E915027837B59

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      current_label_review_required
      Source IDH51-BA3EB99DFFB51692336742FE
      Summary
      Renal dosing status has not been locally normalized; use the current package insert before ordering or administration.
      Source IDH51-41278A5C0E2360094FEFE953
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-008CC2F728F1BC23F0C0B7E8

      Historical Common IV uses

      Recovered v5.1 source content; historical, awaiting current review.

      1. Partial-onset seizure treatment when oral administration is temporarily not feasible
        Source IDH51-6E85DCEADFC2FFC8AB5E5437

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Somnolence, dizziness, fatigue, and psychiatric adverse reactions.
        Source IDH51-C8DEC066EFD23BAFB03E59AF

      Historical Monitoring

      Recovered v5.1 source content; historical, awaiting current review.

      1. Seizure control
        Source IDH51-31068A6A2C4DCC6982B794D0
      2. Sedation and behavior
        Source IDH51-7CD10BD91F63AEBA4C146C47
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      brivaracetam
      Source IDH51-FB163F3779AC84185704AAF4
      Generic name
      Brivaracetam
      Source IDH51-F15CC64A739830BC2E54DD5A
      Brand names
      1. Briviact
        Source IDH51-38C5EF22B87158474DCA9741
      Class
      Neurology and anticonvulsants
      Source IDH51-12068B6EB37B3187FF68EE14
      Subclass
      SV2A anticonvulsant
      Source IDH51-03E410A0C115FBEDDABD05B2
      Summary
      Ready-to-use IV anticonvulsant that may be administered undiluted by short IV injection or diluted for infusion.
      Source IDH51-2378A44BCAC22290F67FBC7F
      Populations
      1. Adult
        Source IDH51-1E2349ECFC3CA92A38E2469F
      2. Pediatric per current label
        Source IDH51-7246DAB341256D35035F0616
      Evidence tier
      Core reference - verify current label
      Source IDH51-376FA5921834BCBF7F4EDCA5
      High alert
      false
      Source IDH51-668563667C4AA4ADF795D599
      Hazardous
      false
      Source IDH51-F492B4D80B2A256951D604C8
      Status
      Active
      Source IDH51-6C85385F8DEA7C2D46CD4A93
      Reviewed
      2026-08-29
      Source IDH51-439938CD62BF87984D2A1288
      Version added
      1.2
      Source IDH51-8497E54F5E1FDDC6E36932B0
      Sources
      LabelUrlKind
      Source IDH51-6A9F08ACBEE7A25A8A664733
      DailyMed label search
      Source IDH51-EC2351F654DD10F410D9148F
      		https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Brivaracetam (opens in a new tab)
      Source IDH51-7573FFC60D1C7B2954035AEB
      		Primary
      Source IDH51-E5D2099F5042A03823A4CE44
      Source IDH51-37F1A52CF72744E860EF4339
      GlobalRPh legacy IV dilution monograph
      Source IDH51-8765DC7337672C326E072222
      		legacy:auto
      Source IDH51-629E4DC337F97B7D8E0C7034
      		Legacy
      Source IDH51-34FC6C3986310F30CF2D2EFD
      Legacy title
      Brivaracetam (Briviact)
      Source IDH51-2F67CB20CFBDDB66FEBCE873
      Clinical release verification
      Audit version
      3.4
      Source IDH51-240F869E8F7140AC214D4D75
      Audited on
      2026-08-30
      Source IDH51-AE9D96F548794BFBACB7B0DB
      Level
      amber
      Source IDH51-B7DA57471C19C3E0DCA294B4
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-04D3635966FDAF3FA3F6B779
      Exact current label candidate
      false
      Source IDH51-9B115D73FF6FAAEBBEFBF6C1
      Numeric support ratio
      0
      Source IDH51-8AA4EBDD04B1D1CFD864E268
      Reference url count
      1
      Source IDH51-082F379B56163E8BF3A861E6
      Broken reference count
      0
      Source IDH51-78576E04168F4CA9B47882DD
      Point of use confirmation required
      true
      Source IDH51-7958D217B26F223D8CEE6FF3
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-FDAC0BC79261687D7C930FDD
      Version updated
      5.1
      Source IDH51-AE4B02D4399D9B55461ED604

      Dosing source fields

      Id
      brivaracetam
      Source IDH51-2C5528878D1D4ADB8A2ED43C
      Generic name
      Brivaracetam
      Source IDH51-5031AE003DAF8ABEC11B2F88
      Coverage status
      direct_official_label_access_plus_local_snapshot
      Source IDH51-CF49FD9D35684AD6D63D7DC5
      Package insert
      Query name
      Brivaracetam
      Source IDH51-A17CD7F72116B356BA782C24
      Product and route must match
      true
      Source IDH51-D82633CD1130357962687014
      Live current label enabled
      false
      Source IDH51-EE436A4E640357E67C3E2F00
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-7A821B7FE19D009551FE627C
      Direct official label access enabled
      true
      Source IDH51-BAFD986FD15B28DCF8CCCEAD
      Outbound server request required
      false
      Source IDH51-EEEB2EBF79156A096D764475
      Local summary status
      not_bundled
      Source IDH51-A91961FA0986E75A23CD2FD2
      Clinical review
      Locally normalized
      false
      Source IDH51-9F83F0793DCA29F3A90C5BCE
      Reviewed
      2026-08-29
      Source IDH51-79AA1D745D3302CA51599268
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-1A4AE7AC9D8B0B302F203709
      Clinical release verification
      Audit version
      3.4
      Source IDH51-FDA52748F20FAFD4D466B519
      Audited on
      2026-08-30
      Source IDH51-E4E6BAE13570BCCE76C5A2E2
      Level
      amber
      Source IDH51-690AD8281A1B2DC3730B003E
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-393D82F4C5A9D4446FA20782
      Exact current label candidate
      false
      Source IDH51-7BEDF118B43D2A0515232960
      Numeric support ratio
      0
      Source IDH51-602C1766530443DD4C10FC02
      Reference url count
      1
      Source IDH51-4A7FF7414891FA0DD6EB8FA5
      Broken reference count
      0
      Source IDH51-7F13C98A7BCD5F82E7D910C2
      Point of use confirmation required
      true
      Source IDH51-4A100B70D0442908F39C1321
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-44A91B230339BCB732E2E74D
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      brivaracetam
      Source IDH51-EB65FFABA10839F3F976CC55
      Name
      Brivaracetam
      Source IDH51-24ADB5C30D0860490B84A618
      Brands
      Briviact
      Source IDH51-39F6830A74676A9B65A99CC9
      Therapeutic class
      Neurology and anticonvulsants
      Source IDH51-5DE715AE81710326C20E6019
      Review version
      3.1
      Source IDH51-033E65C355DFA36A48429D3B
      Review date
      2026-08-30
      Source IDH51-A9D5F34131BC5391F6F16620
      Release status
      structured_record_current_label_not_confirmed
      Source IDH51-3E5F0994380E5762FFEFF809
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-65B0441674F787963991F602
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-99DA3C952A5FDE6C42A8A9DD
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-6062F98A78A6D9F6559A300C
      Reconstitution concentration
      No reconstitution required.
      Source IDH51-28A774052925702E6A1738C8
      Maximum or recommended final concentration
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-D1C8AD0767095C3736B65A4B
      Appropriate standardized containers
      Syringe or small bag
      Source IDH51-C1B903E22C820EC44AE9A231
      Adult dosing range
      Same total daily dose and frequency as oral regimen Prescribed dose Prescribed dose
      Source IDH51-0EA8BAA93CD7924EC64D5F0B
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-80D0EC1E4E0BAC3F889A6EAB
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-01F293CE8E5493380A065F2F
      Infusion time
      IV injection over 2 to 15 minutes or infusion per label Over 2 to 15 minutes
      Source IDH51-6CF260C8D59A01B539F30634
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-EAC236C1F40F60E58932B4FB
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-BBCE0CA071C3080D776BB41B
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-3F6E63BDA8D8747E287C7113
      Reconstitution concentration
      Primary
      existing_structured_record
      Source IDH51-8015AE6B870D0A11D1692C17
      Maximum or recommended final concentration
      Primary
      not_found
      Source IDH51-509034B7BBA1D6464E6AF688
      Appropriate standardized containers
      Primary
      existing_structured_record
      Source IDH51-A601058D560D3E0AB70B175F
      Adult dosing range
      Primary
      existing_structured_record
      Source IDH51-648066F9A820D56706AEDF6A
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-F43DC52AB1C544E44EB57F67
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-A46356867702AE2EFCC4ED31
      Infusion time
      Primary
      existing_structured_record
      Source IDH51-765B2D18F42C8A34CFEEDDFC
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-9DA76151C5B3D6EFD93A9661
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-85AE4196B3F647410E675783
      Population applicability
      Adult
      Applicability
      supported_or_source_present
      Source IDH51-95A1C25FA2D1B50D854C276C
      Guide generation allowed
      true
      Source IDH51-C5E457BBBD950FE24DC6FD11
      Pediatric
      Applicability
      supported_or_source_present
      Source IDH51-56A5671F44EE962EA502B8B3
      Guide generation allowed
      false
      Source IDH51-2EB3453218CC68109A2C8B99
      Neonatal
      Applicability
      not_established
      Source IDH51-77BDE9244A35F690FCC25043
      Guide generation allowed
      false
      Source IDH51-3EC81C71589FE1560C2B4219
      Route presence
      Structured dilution
      true
      Source IDH51-0DAB430BF9E89E175224AD31
      Iv push
      true
      Source IDH51-22651D87A2EA62868E96A349
      Continuous infusion
      false
      Source IDH51-645208885DDBE3DC7C722157
      Pediatric source
      true
      Source IDH51-9A93EB9F581FC2EDD612C0CA
      Neonatal source
      false
      Source IDH51-264F6E12EB93AD77E0FDE01D
      Legacy reference
      Status
      not_available
      Source IDH51-BD07D867C8830019F4F4F0AD
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-0301788EAF50AE97B18B699B
      Source files
      1. catalog.json
        Source IDH51-66214EB0FB9AF85024621E7A
      2. dosing.json
        Source IDH51-DC3FB9F2BF3F94425053E1DF
      3. legacy-map.json
        Source IDH51-2E0CB4C7E49CEA5034A473C0
      4. new-in-v1.2.json
        Source IDH51-ED9B421CEE8B44FA08FA15E5
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-348EC4DD1C9851405A8A240F
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-FB163F3779AC84185704AAF4catalog.json
      /records/35/id      		Historical; current review incomplete
      H51-F15CC64A739830BC2E54DD5Acatalog.json
      /records/35/generic_name      		Historical; current review incomplete
      H51-38C5EF22B87158474DCA9741catalog.json
      /records/35/brand_names/0      		Historical; current review incomplete
      H51-12068B6EB37B3187FF68EE14catalog.json
      /records/35/class      		Historical; current review incomplete
      H51-03E410A0C115FBEDDABD05B2catalog.json
      /records/35/subclass      		Historical; current review incomplete
      H51-2378A44BCAC22290F67FBC7Fcatalog.json
      /records/35/summary      		Historical; current review incomplete
      H51-6E85DCEADFC2FFC8AB5E5437catalog.json
      /records/35/common_uses/0      		Historical; current review incomplete
      H51-8449C72150D4D13B4C4F767Dcatalog.json
      /records/35/preparations/0      		Historical; current review incomplete
      H51-7ED97EB03D2665FA8014B0B9catalog.json
      /records/35/preparations/0/population      		Historical; current review incomplete
      H51-D45DE54C7ADCBE88060B07B9catalog.json
      /records/35/preparations/0/amount      		Historical; current review incomplete
      H51-19FB8AD00228E64046AF8271catalog.json
      /records/35/preparations/0/reconstitution      		Historical; current review incomplete
      H51-1F59C491812E905E48771DA6catalog.json
      /records/35/preparations/0/diluent      		Historical; current review incomplete
      H51-F9D9FDDE4B841199448E533Fcatalog.json
      /records/35/preparations/0/final_volume      		Historical; current review incomplete
      H51-C03605E858017ACDFDCBBBA6catalog.json
      /records/35/preparations/0/concentration      		Historical; current review incomplete
      H51-4B91DC5C8B53BE7A1D66E965catalog.json
      /records/35/preparations/0/rate      		Historical; current review incomplete
      H51-6988E04ACFC34DAC30168763catalog.json
      /records/35/preparations/0/stability      		Historical; current review incomplete
      H51-09BB193A8BAD7066E26E9E85catalog.json
      /records/35/preparations/0/notes      		Historical; current review incomplete
      H51-ABCC83997A29F558CF8A0F99catalog.json
      /records/35/iv_push/0      		Historical; current review incomplete
      H51-581FAEF2901265835245046Fcatalog.json
      /records/35/iv_push/0/population      		Historical; current review incomplete
      H51-F30B2F05EADCA9CC17BCCBF0catalog.json
      /records/35/iv_push/0/dose_scope      		Historical; current review incomplete
      H51-FE3DE50682417846789B07F7catalog.json
      /records/35/iv_push/0/concentration      		Historical; current review incomplete
      H51-1161CCC41248BF394DCB950Bcatalog.json
      /records/35/iv_push/0/rate      		Historical; current review incomplete
      H51-F856621C4DECFCFFB13F4D0Dcatalog.json
      /records/35/iv_push/0/status      		Historical; current review incomplete
      H51-7E73A1C6777D7E565106D14Ccatalog.json
      /records/35/iv_push/0/notes      		Historical; current review incomplete
      H51-C8DEC066EFD23BAFB03E59AFcatalog.json
      /records/35/warnings/0      		Historical; current review incomplete
      H51-31068A6A2C4DCC6982B794D0catalog.json
      /records/35/monitoring/0      		Historical; current review incomplete
      H51-7CD10BD91F63AEBA4C146C47catalog.json
      /records/35/monitoring/1      		Historical; current review incomplete
      H51-1E2349ECFC3CA92A38E2469Fcatalog.json
      /records/35/populations/0      		Historical; current review incomplete
      H51-7246DAB341256D35035F0616catalog.json
      /records/35/populations/1      		Historical; current review incomplete
      H51-376FA5921834BCBF7F4EDCA5catalog.json
      /records/35/evidence_tier      		Historical; current review incomplete
      H51-668563667C4AA4ADF795D599catalog.json
      /records/35/high_alert      		Historical; current review incomplete
      H51-F492B4D80B2A256951D604C8catalog.json
      /records/35/hazardous      		Historical; current review incomplete
      H51-6C85385F8DEA7C2D46CD4A93catalog.json
      /records/35/status      		Historical; current review incomplete
      H51-439938CD62BF87984D2A1288catalog.json
      /records/35/reviewed      		Historical; current review incomplete
      H51-8497E54F5E1FDDC6E36932B0catalog.json
      /records/35/version_added      		Historical; current review incomplete
      H51-6A9F08ACBEE7A25A8A664733catalog.json
      /records/35/sources/0      		Historical; current review incomplete
      H51-EC2351F654DD10F410D9148Fcatalog.json
      /records/35/sources/0/label      		Historical; current review incomplete
      H51-7573FFC60D1C7B2954035AEBcatalog.json
      /records/35/sources/0/url      		Historical; current review incomplete
      H51-E5D2099F5042A03823A4CE44catalog.json
      /records/35/sources/0/kind      		Historical; current review incomplete
      H51-37F1A52CF72744E860EF4339catalog.json
      /records/35/sources/1      		Historical; current review incomplete
      H51-8765DC7337672C326E072222catalog.json
      /records/35/sources/1/label      		Historical; current review incomplete
      H51-629E4DC337F97B7D8E0C7034catalog.json
      /records/35/sources/1/url      		Historical; current review incomplete
      H51-34FC6C3986310F30CF2D2EFDcatalog.json
      /records/35/sources/1/kind      		Historical; current review incomplete
      H51-2F67CB20CFBDDB66FEBCE873catalog.json
      /records/35/legacy_title      		Historical; current review incomplete
      H51-240F869E8F7140AC214D4D75catalog.json
      /records/35/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-AE9D96F548794BFBACB7B0DBcatalog.json
      /records/35/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-B7DA57471C19C3E0DCA294B4catalog.json
      /records/35/clinical_release_verification/level      		Historical; current review incomplete
      H51-04D3635966FDAF3FA3F6B779catalog.json
      /records/35/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-9B115D73FF6FAAEBBEFBF6C1catalog.json
      /records/35/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-2AD9C795F74BA58C3AEAF39Acatalog.json
      /records/35/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-97AE8AE8C963C7749C114C7Acatalog.json
      /records/35/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-8AA4EBDD04B1D1CFD864E268catalog.json
      /records/35/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-082F379B56163E8BF3A861E6catalog.json
      /records/35/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-78576E04168F4CA9B47882DDcatalog.json
      /records/35/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-7958D217B26F223D8CEE6FF3catalog.json
      /records/35/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-FDAC0BC79261687D7C930FDDcatalog.json
      /records/35/clinical_release_verification/note      		Historical; current review incomplete
      H51-60C6D32244D2BE5C59D4D540catalog.json
      /records/35/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-AE4B02D4399D9B55461ED604catalog.json
      /records/35/version_updated      		Historical; current review incomplete
      H51-DBB11503657BD9831C4A0736dailymed-label-snapshots-v5.1.json
      /records/8/id      		Historical; current review incomplete
      H51-0E8D4832772D8255A3F678A3dailymed-label-snapshots-v5.1.json
      /records/8/catalog_name      		Historical; current review incomplete
      H51-34CA0471829F996055A11EB6dailymed-label-snapshots-v5.1.json
      /records/8/selection_status      		Historical; current review incomplete
      H51-8CDC4C44541311E3231F47DCdailymed-label-snapshots-v5.1.json
      /records/8/confidence      		Historical; current review incomplete
      H51-657E71E1428C08A3A9DC3326dailymed-label-snapshots-v5.1.json
      /records/8/match_path      		Historical; current review incomplete
      H51-91055FBEF294EA4BF00A2676dailymed-label-snapshots-v5.1.json
      /records/8/brand_name      		Historical; current review incomplete
      H51-9C7BC5299752156989965D2Adailymed-label-snapshots-v5.1.json
      /records/8/label_title      		Historical; current review incomplete
      H51-C662AEF837A85189FBD5E328dailymed-label-snapshots-v5.1.json
      /records/8/setid      		Historical; current review incomplete
      H51-C8C8AF1D70C6A2B849F8BB7Bdailymed-label-snapshots-v5.1.json
      /records/8/route      		Historical; current review incomplete
      H51-A7156840E4C0CA56749310CDdailymed-label-snapshots-v5.1.json
      /records/8/dosage_form      		Historical; current review incomplete
      H51-E9C9953E9BB0769ACD5F1042dailymed-label-snapshots-v5.1.json
      /records/8/dosage_administration_summary/0      		Historical; current review incomplete
      H51-1DFCA956F33BC057430BAA22dailymed-label-snapshots-v5.1.json
      /records/8/dosage_administration_summary/1      		Historical; current review incomplete
      H51-178CB9661ECD731847D7E7F3dailymed-label-snapshots-v5.1.json
      /records/8/dosage_administration_summary/2      		Historical; current review incomplete
      H51-A7AC145A7BF3409AD80B15B1dailymed-label-snapshots-v5.1.json
      /records/8/dosage_forms_strengths/0      		Historical; current review incomplete
      H51-8EFBB8A8547D9319FEBA319Bdailymed-label-snapshots-v5.1.json
      /records/8/mechanism_summary      		Historical; current review incomplete
      H51-5739834AFF75D6CF856109A3dailymed-label-snapshots-v5.1.json
      /records/8/scope_note      		Historical; current review incomplete
      H51-E636FD7602BCA34DB4A5D0AEdailymed-label-snapshots-v5.1.json
      /records/8/labeler      		Historical; current review incomplete
      H51-6CAD713E5F32DF646495323Bdailymed-label-snapshots-v5.1.json
      /records/8/official_label_url      		Historical; current review incomplete
      H51-69F67B3011637650499D33CAdailymed-label-snapshots-v5.1.json
      /records/8/reviewed_on      		Historical; current review incomplete
      H51-5C7DA0FBB35D4ECF1DF15957dailymed-label-snapshots-v5.1.json
      /records/8/mechanism_source      		Historical; current review incomplete
      H51-751A177FB0A1EE2AEF3F3BE2dailymed-label-snapshots-v5.1.json
      /records/8/source_sections/0      		Historical; current review incomplete
      H51-220D14A875C9865EFDEFE564dailymed-label-snapshots-v5.1.json
      /records/8/source_sections/1      		Historical; current review incomplete
      H51-FD67033D74168D1BDC31821Bdailymed-label-snapshots-v5.1.json
      /records/8/source_sections/2      		Historical; current review incomplete
      H51-16A3FDBC9AE564636C6C2808dailymed-label-snapshots-v5.1.json
      /records/8/retrieval_method      		Historical; current review incomplete
      H51-FFD5D74D2D509F510E228242dailymed-label-snapshots-v5.1.json
      /records/8/label_status      		Historical; current review incomplete
      H51-DDA3629128A8E618A090555Ddailymed-label-snapshots-v5.1.json
      /records/8/disclaimer      		Historical; current review incomplete
      H51-2C5528878D1D4ADB8A2ED43Cdosing.json
      /records/35/id      		Historical; current review incomplete
      H51-5031AE003DAF8ABEC11B2F88dosing.json
      /records/35/generic_name      		Historical; current review incomplete
      H51-CF49FD9D35684AD6D63D7DC5dosing.json
      /records/35/coverage_status      		Historical; current review incomplete
      H51-A17CD7F72116B356BA782C24dosing.json
      /records/35/package_insert/query_name      		Historical; current review incomplete
      H51-75A2909A56D8607D783CFC2Bdosing.json
      /records/35/package_insert/preferred_setid      		Historical; current review incomplete
      H51-D82633CD1130357962687014dosing.json
      /records/35/package_insert/product_and_route_must_match      		Historical; current review incomplete
      H51-EE436A4E640357E67C3E2F00dosing.json
      /records/35/package_insert/live_current_label_enabled      		Historical; current review incomplete
      H51-7A821B7FE19D009551FE627Cdosing.json
      /records/35/package_insert/source_priority      		Historical; current review incomplete
      H51-BAFD986FD15B28DCF8CCCEADdosing.json
      /records/35/package_insert/direct_official_label_access_enabled      		Historical; current review incomplete
      H51-EEEB2EBF79156A096D764475dosing.json
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      H51-A91961FA0986E75A23CD2FD2dosing.json
      /records/35/package_insert/local_summary_status      		Historical; current review incomplete
      H51-BA3EB99DFFB51692336742FEdosing.json
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      H51-41278A5C0E2360094FEFE953dosing.json
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      H51-008CC2F728F1BC23F0C0B7E8dosing.json
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      H51-8D319EC8C0233CE00FAD3784dosing.json
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      H51-FCC526A990AD29F10FBA308Fdosing.json
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      H51-4DF55135EC2F307A24C0B671dosing.json
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      H51-005C51DE6E454B4089EF7221dosing.json
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      H51-4C8B6BD7949F7AE88533DA9Fdosing.json
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      H51-CAB936D5DB6FFAF5AD47B2A9dosing.json
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      H51-6A099F3C3D3F2091F4C16ABCdosing.json
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      H51-9A98688D28D2B7A28220EA6Ddosing.json
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      H51-9F83F0793DCA29F3A90C5BCEdosing.json
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      H51-FD19508ED88759CE7CE96EFCfirst-look-v5.1.json
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      /35/clinical_release_note      		Historical; current review incomplete

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