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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Medication reference

Bivalirudin

Monograph awaiting updateThis monograph will be updated in the future.

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No original site article was mapped to this record. The available historical structured fields and official-source links are retained.

Historical first look: uses, mechanism, dosing context, and administration

Recovered v5.1 source content; historical, awaiting current review.

Id
bivalirudin
Source IDH51-1465B0727C6A0B2833F131FF
Generic name
Bivalirudin
Source IDH51-A57F9C19A614204C77F3EE4D
Class
Anticoagulation and hemostasis
Source IDH51-9459166B51E5AFA96781FFAE
Subclass
Direct thrombin inhibitor
Source IDH51-1567ED11E6E2B2B1FF807966
Primary uses
  1. Percutaneous coronary intervention
    Source IDH51-90EDE30C0988DB14C43CD594
  2. Selected HIT or extracorporeal support protocols
    Source IDH51-C4C7153AF8FE9CCA997D2964
Mechanism
Directly inhibits thrombin without requiring antithrombin.
Source IDH51-F69F39F0440DE0B3C7968606
Mechanism level
drug_specific
Source IDH51-01B0FCED30CBBFF6481095B4
Basic dosing orientation
Adult PCI | Existing preparation record; use current package insert for indication-specific selection | 250 mg vial | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult PCI | 0.75 mg/kg label-standard bolus in common regimen | 0.75 mg/kg label-standard bolus in common regimen | Patient- and indication-specific | See current package insert | IV push
Source IDH51-A68EEB4CB6D0330C588A4833
Administration orientation
Bolus followed by weight-based infusion per PCI protocol; IV bolus immediately before infusion; 5 mg/mL; IV bolus immediately before infusion
Source IDH51-0B5F8ED82AFB09108CBFE5DA
Renal and population orientation
Separate renal reference: Open Renal Dosing Master (opens in a new tab)Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method.
Source IDH51-0BA43A78BEE689F2EDC4D720
Key safety orientation
  1. Major bleeding.
    Source IDH51-96739A9A251D038F0957FE6C
  2. Indication-specific protocols are not interchangeable.
    Source IDH51-EB0FD10FCABF3347FDA000C1
Coverage path
structured_local_snapshot
Source IDH51-9CE0394D9221C43515911BD5
Coverage path label
Structured GlobalRPh route snapshot
Source IDH51-5FFC11DCFA75365765201F2C
Review note
First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
Source IDH51-DC257AD7183D71888F1DC6F8
Search text
Bivalirudin Anticoagulation and hemostasis Direct thrombin inhibitor Percutaneous coronary intervention Selected HIT or extracorporeal support protocols Directly inhibits thrombin without requiring antithrombin. Adult PCI | Existing preparation record; use current package insert for indication-specific selection | 250 mg vial | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult PCI | 0.75 mg/kg label-standard bolus in common regimen | 0.75 mg/kg label-standard bolus in common regimen | Patient- and indication-specific | See current package insert | IV push Bolus followed by weight-based infusion per PCI protocol; IV bolus immediately before infusion; 5 mg/mL; IV bolus immediately before infusion Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method. Major bleeding. Indication-specific protocols are not interchangeable. Structured GlobalRPh route snapshot
Source IDH51-93CEE2F813E4CFE306CC59D3
Official access mode
search
Source IDH51-3ABBFB6B7398B3D3D1265A66
Official search query
Bivalirudin
Source IDH51-83726B76AD693F4B010F06CC
Official access reason
A source-backed DailyMed search is available; select and confirm the exact IV product.
Source IDH51-DF349FC507CEBA26A344A3EC
Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • Retrievable exact-product SPL XML with version, revision, retrieval date and reproducible hash
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
adjustment_required
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.

      No separate structured rows were bundled for dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical dilution and intermittent infusion preparation

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      PopulationAmountReconstitutionDiluentFinal volumeConcentrationRateStabilityNotes
      Source IDH51-25D9D85A2D0EF892D22041E3
      Adult PCI
      Source IDH51-2C7794BB42C49D287227BEE3
      		250 mg vial
      Source IDH51-CA5129A891435373D16251D8
      		Reconstitute with 5 mL Sterile Water for Injection, then further dilute.
      Source IDH51-4F20FC3D0B830709F45AC51D
      		D5W or NS
      Source IDH51-FCDDA8110043B0E6B1A7EC9A
      		50 mL for 5 mg/mL or protocol-specific
      Source IDH51-490DD186CF5742FAEA561462
      		Commonly 5 mg/mL for PCI
      Source IDH51-B502A751198E068AB680E28F
      		Bolus followed by weight-based infusion per PCI protocol
      Source IDH51-F9814FAC5A270D46FA3028E1
      		Use the shorter of current product labeling, validated stability data, and the applicable USP <797> sterility-based BUD ceiling.
      Source IDH51-50017576B46DD975D30367FC
      		Renal adjustment affects infusion, especially at severe impairment or dialysis.
      Source IDH51-6F92328E78EAEB3B1F0DA557

      Historical IV-push guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationDose scopeConcentrationRateStatus
      Source IDH51-0F0C5BD8B6A472C59FEBF8D0
      Adult PCI
      Source IDH51-F95FB313F1648A2017EAB643
      		0.75 mg/kg label-standard bolus in common regimen
      Source IDH51-424A7114AB5D3BC4C77F9562
      		5 mg/mL
      Source IDH51-0A67E83B7CEDAFE54AD0EAA7
      		IV bolus immediately before infusion
      Source IDH51-BAABED4A0E4A9D23691F517E
      		PCI protocol only
      Source IDH51-E482BA77CF4858A2F3902833

      Historical continuous-infusion guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      PopulationStandard concentrationInitial rateTitrationMaximumNotes
      Source IDH51-CF949CE4CC0994E5405732B8
      Adult PCI
      Source IDH51-071808AD0F62E974C47FED44
      		5 mg/mL
      Source IDH51-4E2013FC8C6B4C10D7B9C44B
      		1.75 mg/kg/hour after bolus in common label regimen
      Source IDH51-558E86A40F46974CEB0F2EC0
      		Adjust for renal function and procedural plan
      Source IDH51-53CB8736548F827DEBFD9DF9
      		Protocol-specific
      Source IDH51-2F9859C31EEFF5969B8BC8DC
      		Do not use the PCI regimen for other indications.
      Source IDH51-D267DD7CB93E2AF667B0DD7B

      Historical indication and population dosing

      Recovered tables and source-separated snapshots; full clinical revalidation remains pending.

      Existing dose and route snapshots

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      RoutePopulationIndicationDoseIntervalDurationAdministrationSource levelNotes
      Source IDH51-C8887BA802E2AB37F708AAE1
      IV infusion
      Source IDH51-369C56FE1A6E1F3E8E1D6D10
      		Adult PCI
      Source IDH51-8195205FD3E5FE6ED7F31FE9
      		Existing preparation record; use current package insert for indication-specific selection
      Source IDH51-CE57EBA65818D285B8DDEBA7
      		250 mg vial
      Source IDH51-A967C0EBD66154B0E1B017BD
      		Not normalized in the preparation record
      Source IDH51-8A47134757A6D449087CB944
      		See current package insert and professional guidance
      Source IDH51-A4EE1BA3C42779AA948D1A8E
      		Bolus followed by weight-based infusion per PCI protocol
      Source IDH51-035D7B5A002934264FB40312
      		Existing GlobalRPh structured preparation snapshot
      Source IDH51-77E30607A34EBB58BC658D7E
      		Renal adjustment affects infusion, especially at severe impairment or dialysis.
      Source IDH51-88E64BC46ADC40146A6E2477
      Source IDH51-852AC8BE6F32C7BBF760F2EE
      IV push
      Source IDH51-C70AA014FCA5603901EAE13F
      		Adult PCI
      Source IDH51-EC5D9B9693669FFACFC0BC21
      		0.75 mg/kg label-standard bolus in common regimen
      Source IDH51-F25350E13CBC1D2209CEB1D7
      		0.75 mg/kg label-standard bolus in common regimen
      Source IDH51-E6598B01BD15F1BC1267642A
      		Patient- and indication-specific
      Source IDH51-FB1CEACBB3C776B78FB4EFC9
      		See current package insert
      Source IDH51-E3CCE43B25E77BE759899797
      		IV bolus immediately before infusion
      Source IDH51-17C449BFEB0515F4370C32A3
      		Existing GlobalRPh IV push snapshot
      Source IDH51-BC334E47631DD15BF48E8F90
      		PCI protocol only
      Source IDH51-521284FFFAD11CA6AAC65340
      Source IDH51-637AE636BA5438F6CADB251F
      Continuous IV infusion
      Source IDH51-A91A609E91115DC5C9C49D3F
      		Adult PCI
      Source IDH51-C59B4BCAAA715FAB97F5B8E4
      		Existing continuous-infusion record
      Source IDH51-20FD116618A4B91E63661F08
      		1.75 mg/kg/hour after bolus in common label regimen
      Source IDH51-B88AA534109E81EA43D17F87
      		Continuous infusion; titration-specific
      Source IDH51-C31E5DB8B2946528AA673FBB
      		Clinical-response dependent
      Source IDH51-0A3221F7C5CE07788F2D6F14
      		Adjust for renal function and procedural plan
      Source IDH51-4249D82CAD4D605E5DAA1890
      		Existing GlobalRPh continuous-infusion snapshot
      Source IDH51-8F80C36FB07236FE438AA0CB
      		Protocol-specific Do not use the PCI regimen for other indications.
      Source IDH51-3CCFD51DF571C9913C7C9B6E

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      adjustment_required
      Source IDH51-198112B094ED21EB529A020A
      Summary
      Renal dose adjustment or interval modification is commonly required; verify the selected product label and patient-specific renal method.
      Source IDH51-CB63BBDC6DB99833C5083144
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-E906431F77A60E18DC12C23F

      Historical Common IV uses

      Recovered v5.1 source content; historical, awaiting current review.

      1. Percutaneous coronary intervention
        Source IDH51-22CB6C9C829C871F3F5BBF2A
      2. Selected HIT or extracorporeal support protocols
        Source IDH51-B10DB31149BA9CADACA15CA6

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Major bleeding.
        Source IDH51-F0351DF3EBE2572C44C50530
      2. Indication-specific protocols are not interchangeable.
        Source IDH51-6582CE9BFDF8DEF47E96DAF7

      Historical Monitoring

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      1. ACT during PCI
        Source IDH51-A28207FA3A1298CEDE96DAB0
      2. CBC and bleeding
        Source IDH51-1F5E3CCE12BD0FB71DC4E6E5
      3. Renal function
        Source IDH51-DE65214CF14A77F1B2F2D91C
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      bivalirudin
      Source IDH51-A83F6F1BF290E34C810A4CB3
      Generic name
      Bivalirudin
      Source IDH51-C120848803268AD099E284FC
      Brand names
      1. Angiomax
        Source IDH51-7095DCC4ED3247C1F96044C2
      Class
      Anticoagulation and hemostasis
      Source IDH51-432D7FBEE706779AD6843F1B
      Subclass
      Direct thrombin inhibitor
      Source IDH51-AE1F767F87327E8857933595
      Summary
      Short-acting direct thrombin inhibitor used in PCI and selected HIT/cardiac protocols; dilution and dose vary by indication.
      Source IDH51-DD1B7697139D7E39457192B0
      Populations
      1. Adult
        Source IDH51-FA3315B2B5FB604C12EE70EF
      Evidence tier
      Core reference - verify current label
      Source IDH51-B9D60A5F555B54FA8EF896CA
      High alert
      true
      Source IDH51-4451330C7D0253AAC4E54D3E
      Hazardous
      false
      Source IDH51-4194F6BD160E3DB7C434CC51
      Status
      Active
      Source IDH51-E7AB48C9B1D707A831F12507
      Reviewed
      2026-08-29
      Source IDH51-AF7A38946EF67CFCF3002D4D
      Version added
      1.2
      Source IDH51-EFE929E764AD5669C78735A6
      Sources
      LabelUrlKind
      Source IDH51-AA55BC7BBE6B7F446E6971EB
      DailyMed label search
      Source IDH51-557ECC85D21894F32B29A984
      		https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Bivalirudin (opens in a new tab)
      Source IDH51-B6AFAF486F75CBF24204FBD8
      		Primary
      Source IDH51-4CBC0E3BCAE2F44FD97C6C6A
      Source IDH51-D992521F5ED73208111D11FA
      GlobalRPh legacy IV dilution monograph
      Source IDH51-5D9E15723369343EF98AF28C
      		legacy:auto
      Source IDH51-006C2D8FEFD3BC295ADB8D5F
      		Legacy
      Source IDH51-B3D69A7177EB48F48BB0B785
      Clinical release verification
      Audit version
      3.4
      Source IDH51-3516FACD7B3BE1161C2DCBB4
      Audited on
      2026-08-30
      Source IDH51-D019B3E8773CFCB5CE13B0E0
      Level
      amber
      Source IDH51-86026D3EDD42131A22B4FB14
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-7337A645AE9D1EF72D33C494
      Exact current label candidate
      false
      Source IDH51-3B77655B1A023EC64CA686A0
      Numeric support ratio
      0
      Source IDH51-6634AEF3CD627AF03D042B2F
      Reference url count
      1
      Source IDH51-06F7E522720A8E35A8AD1C81
      Broken reference count
      0
      Source IDH51-127FFD46F2E1055D58B900B3
      Point of use confirmation required
      true
      Source IDH51-2699783AFE4955D183769957
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-D36DF74E21BA5E5EBDCA1A36

      Dosing source fields

      Id
      bivalirudin
      Source IDH51-6FA9466734096B94A9D9812A
      Generic name
      Bivalirudin
      Source IDH51-FD15FDADAA0EC94C1B804679
      Coverage status
      direct_official_label_access_plus_local_snapshot
      Source IDH51-27761138AE81460986E71FE7
      Package insert
      Query name
      Bivalirudin
      Source IDH51-44E02D9B898441F5C4C33168
      Product and route must match
      true
      Source IDH51-24BD08140B106F819ADE9159
      Live current label enabled
      false
      Source IDH51-E09BC7100D8749827B28B8DA
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-2478B0E101B9CC1FC7BC33F2
      Direct official label access enabled
      true
      Source IDH51-9D7311A43EA7CCD225FBBABC
      Outbound server request required
      false
      Source IDH51-BFBCC1A57ADC3BAC89FF89C0
      Local summary status
      not_bundled
      Source IDH51-1FA3C09DE5CBC4CE4223B3FF
      Clinical review
      Locally normalized
      false
      Source IDH51-F638AF8D2DE499B4BB887497
      Reviewed
      2026-08-29
      Source IDH51-1A475383691DCE83F4A680AF
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-C9BDC477F3037151AF93DA11
      Clinical release verification
      Audit version
      3.4
      Source IDH51-7437021DA3EF08BEFB7E1F82
      Audited on
      2026-08-30
      Source IDH51-43827A12501DF891379BD0F6
      Level
      amber
      Source IDH51-3D55D4EB166F02EB4882C5D6
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-E9DEA6146D9198C821F1CF57
      Exact current label candidate
      false
      Source IDH51-0692C53A45C8117AE25DCE3A
      Numeric support ratio
      0
      Source IDH51-320F5F603501D1FBDB3F026E
      Reference url count
      1
      Source IDH51-59DE4A7E63E3A1186C060302
      Broken reference count
      0
      Source IDH51-E549A70659DAFFC35982ED36
      Point of use confirmation required
      true
      Source IDH51-18145D3937DF3C6851B2F6B6
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-4C51707993F07339C2D29E8F
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      bivalirudin
      Source IDH51-C7DD899F74C7A6D58735C8A7
      Name
      Bivalirudin
      Source IDH51-FFE0EABB6704429FC52EF14E
      Brands
      Angiomax
      Source IDH51-4863266BBCF62753C687DD8A
      Therapeutic class
      Anticoagulation and hemostasis
      Source IDH51-EB40E773BCF31F669C099B7D
      Review version
      3.1
      Source IDH51-59B5699EC301005F44EC9403
      Review date
      2026-08-30
      Source IDH51-9D178B62B7760E2B053084C7
      Release status
      structured_record_current_label_not_confirmed
      Source IDH51-1F74D30E4FF2E9C2D339D7A3
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-63DA3C9DFD41B5D754BD371C
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-9DBF670689B32D73C1B8DB42
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-1B8DB224DADD9D8EF13F9515
      Reconstitution concentration
      Reconstitute with 5 mL Sterile Water for Injection, then further dilute.
      Source IDH51-A88DF6FD2C89B4968E1E5828
      Maximum or recommended final concentration
      5 mg/mL
      Source IDH51-A5E7C11D52BBA97AB1C43A38
      Appropriate standardized containers
      50 mL for 5 mg/mL or protocol-specific
      Source IDH51-A8D3B99A4B5F17674E2357E8
      Adult dosing range
      250 mg vial 0.75 mg/kg label-standard bolus in common regimen 1.75 mg/kg/hour after bolus in common label regimen 0.75 mg/kg label-standard bolus in common regimen
      Source IDH51-0C4574D8E0B2035A44420426
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-73B68201066C45EE1731948B
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-6E43823C12CEF89B32307B77
      Infusion time
      Bolus followed by weight-based infusion per PCI protocol IV bolus immediately before infusion 1.75 mg/kg/hour after bolus in common label regimen
      Source IDH51-4424C51A5E7A3327F61AB48E
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-E6652EA54C19D49A7DCD2570
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-CA5C80714B10A8D7B6CDD27A
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-0CB1BBCA0821EEC27C9F25ED
      Reconstitution concentration
      Primary
      existing_structured_record
      Source IDH51-327A3C275C77280FCB70E7DC
      Maximum or recommended final concentration
      Primary
      existing_structured_record
      Source IDH51-F5342460BADF231DBF7D3ACC
      Appropriate standardized containers
      Primary
      existing_structured_record
      Source IDH51-B542392E1A40425109C5537A
      Adult dosing range
      Primary
      existing_structured_record
      Source IDH51-6DF2C11D483E7C200D881A51
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-4E93F2753DBA4D3D59072523
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-3394BFB8A95B0C0C8BA82958
      Infusion time
      Primary
      existing_structured_record
      Source IDH51-411EF86E039ACD02CF551559
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-1752EFA94DC1998674D003F2
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-63193C9AC1005D979AF0BF8D
      Population applicability
      Adult
      Applicability
      supported_or_source_present
      Source IDH51-0EC8FEF0202CFE8C80D637CA
      Guide generation allowed
      true
      Source IDH51-C419399D92D4856BBB453254
      Pediatric
      Applicability
      not_established
      Source IDH51-0ECF23D1253C775D7CCCD7C3
      Guide generation allowed
      false
      Source IDH51-79E674188F9A9BA20314B70D
      Neonatal
      Applicability
      not_established
      Source IDH51-307CF72A911358F6E1D022BE
      Guide generation allowed
      false
      Source IDH51-B79D60ADC38203C7F14C49A9
      Route presence
      Structured dilution
      true
      Source IDH51-3E5D87A53FB210D299363CC4
      Iv push
      true
      Source IDH51-B796D7B11AA491B5BB4D0DE1
      Continuous infusion
      true
      Source IDH51-E52A4508A261F4164BADF65A
      Pediatric source
      false
      Source IDH51-2047715F66AFC0681AFF45FB
      Neonatal source
      false
      Source IDH51-1F192321602D0DA79A579BA5
      Legacy reference
      Status
      not_available
      Source IDH51-F552B7B13ED96CCAC3E2B0D8
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-49013159DFDBF3692C0A3DD4
      Concentration values detected
      HighUnitText
      Source IDH51-7AF1040AFA089C8EA7012612
      5
      Source IDH51-F86BE8A5A82FEE865D536618
      		mg
      Source IDH51-C5F2B961FA114D09470D333B
      		5 mg/mL
      Source IDH51-FAF7CF2FCC30D181522C1FCA
      Source files
      1. catalog.json
        Source IDH51-E34EB15DBCAFDDB557ABF457
      2. dosing.json
        Source IDH51-94E1C12C41C4F545DBBA1F12
      3. new-in-v1.2.json
        Source IDH51-C0D012C9B719B946868BC127
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-C63E288D9650816C8F2193A0
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-A83F6F1BF290E34C810A4CB3catalog.json
      /records/33/id      		Historical; current review incomplete
      H51-C120848803268AD099E284FCcatalog.json
      /records/33/generic_name      		Historical; current review incomplete
      H51-7095DCC4ED3247C1F96044C2catalog.json
      /records/33/brand_names/0      		Historical; current review incomplete
      H51-432D7FBEE706779AD6843F1Bcatalog.json
      /records/33/class      		Historical; current review incomplete
      H51-AE1F767F87327E8857933595catalog.json
      /records/33/subclass      		Historical; current review incomplete
      H51-DD1B7697139D7E39457192B0catalog.json
      /records/33/summary      		Historical; current review incomplete
      H51-22CB6C9C829C871F3F5BBF2Acatalog.json
      /records/33/common_uses/0      		Historical; current review incomplete
      H51-B10DB31149BA9CADACA15CA6catalog.json
      /records/33/common_uses/1      		Historical; current review incomplete
      H51-25D9D85A2D0EF892D22041E3catalog.json
      /records/33/preparations/0      		Historical; current review incomplete
      H51-2C7794BB42C49D287227BEE3catalog.json
      /records/33/preparations/0/population      		Historical; current review incomplete
      H51-CA5129A891435373D16251D8catalog.json
      /records/33/preparations/0/amount      		Historical; current review incomplete
      H51-4F20FC3D0B830709F45AC51Dcatalog.json
      /records/33/preparations/0/reconstitution      		Historical; current review incomplete
      H51-FCDDA8110043B0E6B1A7EC9Acatalog.json
      /records/33/preparations/0/diluent      		Historical; current review incomplete
      H51-490DD186CF5742FAEA561462catalog.json
      /records/33/preparations/0/final_volume      		Historical; current review incomplete
      H51-B502A751198E068AB680E28Fcatalog.json
      /records/33/preparations/0/concentration      		Historical; current review incomplete
      H51-F9814FAC5A270D46FA3028E1catalog.json
      /records/33/preparations/0/rate      		Historical; current review incomplete
      H51-50017576B46DD975D30367FCcatalog.json
      /records/33/preparations/0/stability      		Historical; current review incomplete
      H51-6F92328E78EAEB3B1F0DA557catalog.json
      /records/33/preparations/0/notes      		Historical; current review incomplete
      H51-0F0C5BD8B6A472C59FEBF8D0catalog.json
      /records/33/iv_push/0      		Historical; current review incomplete
      H51-F95FB313F1648A2017EAB643catalog.json
      /records/33/iv_push/0/population      		Historical; current review incomplete
      H51-424A7114AB5D3BC4C77F9562catalog.json
      /records/33/iv_push/0/dose_scope      		Historical; current review incomplete
      H51-0A67E83B7CEDAFE54AD0EAA7catalog.json
      /records/33/iv_push/0/concentration      		Historical; current review incomplete
      H51-BAABED4A0E4A9D23691F517Ecatalog.json
      /records/33/iv_push/0/rate      		Historical; current review incomplete
      H51-E482BA77CF4858A2F3902833catalog.json
      /records/33/iv_push/0/status      		Historical; current review incomplete
      H51-839B3DA02912BC5AA399D52Bcatalog.json
      /records/33/iv_push/0/notes      		Historical; current review incomplete
      H51-CF949CE4CC0994E5405732B8catalog.json
      /records/33/continuous_infusions/0      		Historical; current review incomplete
      H51-071808AD0F62E974C47FED44catalog.json
      /records/33/continuous_infusions/0/population      		Historical; current review incomplete
      H51-4E2013FC8C6B4C10D7B9C44Bcatalog.json
      /records/33/continuous_infusions/0/standard_concentration      		Historical; current review incomplete
      H51-558E86A40F46974CEB0F2EC0catalog.json
      /records/33/continuous_infusions/0/initial_rate      		Historical; current review incomplete
      H51-53CB8736548F827DEBFD9DF9catalog.json
      /records/33/continuous_infusions/0/titration      		Historical; current review incomplete
      H51-2F9859C31EEFF5969B8BC8DCcatalog.json
      /records/33/continuous_infusions/0/maximum      		Historical; current review incomplete
      H51-D267DD7CB93E2AF667B0DD7Bcatalog.json
      /records/33/continuous_infusions/0/notes      		Historical; current review incomplete
      H51-F0351DF3EBE2572C44C50530catalog.json
      /records/33/warnings/0      		Historical; current review incomplete
      H51-6582CE9BFDF8DEF47E96DAF7catalog.json
      /records/33/warnings/1      		Historical; current review incomplete
      H51-A28207FA3A1298CEDE96DAB0catalog.json
      /records/33/monitoring/0      		Historical; current review incomplete
      H51-1F5E3CCE12BD0FB71DC4E6E5catalog.json
      /records/33/monitoring/1      		Historical; current review incomplete
      H51-DE65214CF14A77F1B2F2D91Ccatalog.json
      /records/33/monitoring/2      		Historical; current review incomplete
      H51-FA3315B2B5FB604C12EE70EFcatalog.json
      /records/33/populations/0      		Historical; current review incomplete
      H51-B9D60A5F555B54FA8EF896CAcatalog.json
      /records/33/evidence_tier      		Historical; current review incomplete
      H51-4451330C7D0253AAC4E54D3Ecatalog.json
      /records/33/high_alert      		Historical; current review incomplete
      H51-4194F6BD160E3DB7C434CC51catalog.json
      /records/33/hazardous      		Historical; current review incomplete
      H51-E7AB48C9B1D707A831F12507catalog.json
      /records/33/status      		Historical; current review incomplete
      H51-AF7A38946EF67CFCF3002D4Dcatalog.json
      /records/33/reviewed      		Historical; current review incomplete
      H51-EFE929E764AD5669C78735A6catalog.json
      /records/33/version_added      		Historical; current review incomplete
      H51-AA55BC7BBE6B7F446E6971EBcatalog.json
      /records/33/sources/0      		Historical; current review incomplete
      H51-557ECC85D21894F32B29A984catalog.json
      /records/33/sources/0/label      		Historical; current review incomplete
      H51-B6AFAF486F75CBF24204FBD8catalog.json
      /records/33/sources/0/url      		Historical; current review incomplete
      H51-4CBC0E3BCAE2F44FD97C6C6Acatalog.json
      /records/33/sources/0/kind      		Historical; current review incomplete
      H51-D992521F5ED73208111D11FAcatalog.json
      /records/33/sources/1      		Historical; current review incomplete
      H51-5D9E15723369343EF98AF28Ccatalog.json
      /records/33/sources/1/label      		Historical; current review incomplete
      H51-006C2D8FEFD3BC295ADB8D5Fcatalog.json
      /records/33/sources/1/url      		Historical; current review incomplete
      H51-B3D69A7177EB48F48BB0B785catalog.json
      /records/33/sources/1/kind      		Historical; current review incomplete
      H51-E51012A0ECE83B8E451AAC29catalog.json
      /records/33/legacy_title      		Historical; current review incomplete
      H51-3516FACD7B3BE1161C2DCBB4catalog.json
      /records/33/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-D019B3E8773CFCB5CE13B0E0catalog.json
      /records/33/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-86026D3EDD42131A22B4FB14catalog.json
      /records/33/clinical_release_verification/level      		Historical; current review incomplete
      H51-7337A645AE9D1EF72D33C494catalog.json
      /records/33/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-3B77655B1A023EC64CA686A0catalog.json
      /records/33/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-18C0537E771D40084E91092Acatalog.json
      /records/33/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-D84AFA2D158AAEA1525D1845catalog.json
      /records/33/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-6634AEF3CD627AF03D042B2Fcatalog.json
      /records/33/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-06F7E522720A8E35A8AD1C81catalog.json
      /records/33/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-127FFD46F2E1055D58B900B3catalog.json
      /records/33/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-2699783AFE4955D183769957catalog.json
      /records/33/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-D36DF74E21BA5E5EBDCA1A36catalog.json
      /records/33/clinical_release_verification/note      		Historical; current review incomplete
      H51-BD5FA1D1451957437200934Ccatalog.json
      /records/33/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-6FA9466734096B94A9D9812Adosing.json
      /records/33/id      		Historical; current review incomplete
      H51-FD15FDADAA0EC94C1B804679dosing.json
      /records/33/generic_name      		Historical; current review incomplete
      H51-27761138AE81460986E71FE7dosing.json
      /records/33/coverage_status      		Historical; current review incomplete
      H51-44E02D9B898441F5C4C33168dosing.json
      /records/33/package_insert/query_name      		Historical; current review incomplete
      H51-88DA6E5478CD0632D77AF8F8dosing.json
      /records/33/package_insert/preferred_setid      		Historical; current review incomplete
      H51-24BD08140B106F819ADE9159dosing.json
      /records/33/package_insert/product_and_route_must_match      		Historical; current review incomplete
      H51-E09BC7100D8749827B28B8DAdosing.json
      /records/33/package_insert/live_current_label_enabled      		Historical; current review incomplete
      H51-2478B0E101B9CC1FC7BC33F2dosing.json
      /records/33/package_insert/source_priority      		Historical; current review incomplete
      H51-9D7311A43EA7CCD225FBBABCdosing.json
      /records/33/package_insert/direct_official_label_access_enabled      		Historical; current review incomplete
      H51-BFBCC1A57ADC3BAC89FF89C0dosing.json
      /records/33/package_insert/outbound_server_request_required      		Historical; current review incomplete
      H51-1FA3C09DE5CBC4CE4223B3FFdosing.json
      /records/33/package_insert/local_summary_status      		Historical; current review incomplete
      H51-198112B094ED21EB529A020Adosing.json
      /records/33/renal/classification      		Historical; current review incomplete
      H51-CB63BBDC6DB99833C5083144dosing.json
      /records/33/renal/summary      		Historical; current review incomplete
      H51-E906431F77A60E18DC12C23Fdosing.json
      /records/33/renal/method_note      		Historical; current review incomplete
      H51-C8887BA802E2AB37F708AAE1dosing.json
      /records/33/existing_route_snapshots/0      		Historical; current review incomplete
      H51-369C56FE1A6E1F3E8E1D6D10dosing.json
      /records/33/existing_route_snapshots/0/route      		Historical; current review incomplete
      H51-8195205FD3E5FE6ED7F31FE9dosing.json
      /records/33/existing_route_snapshots/0/population      		Historical; current review incomplete
      H51-CE57EBA65818D285B8DDEBA7dosing.json
      /records/33/existing_route_snapshots/0/indication      		Historical; current review incomplete
      H51-A967C0EBD66154B0E1B017BDdosing.json
      /records/33/existing_route_snapshots/0/dose      		Historical; current review incomplete
      H51-8A47134757A6D449087CB944dosing.json
      /records/33/existing_route_snapshots/0/interval      		Historical; current review incomplete
      H51-A4EE1BA3C42779AA948D1A8Edosing.json
      /records/33/existing_route_snapshots/0/duration      		Historical; current review incomplete
      H51-035D7B5A002934264FB40312dosing.json
      /records/33/existing_route_snapshots/0/administration      		Historical; current review incomplete
      H51-77E30607A34EBB58BC658D7Edosing.json
      /records/33/existing_route_snapshots/0/source_level      		Historical; current review incomplete
      H51-88E64BC46ADC40146A6E2477dosing.json
      /records/33/existing_route_snapshots/0/notes      		Historical; current review incomplete
      H51-852AC8BE6F32C7BBF760F2EEdosing.json
      /records/33/existing_route_snapshots/1      		Historical; current review incomplete
      H51-C70AA014FCA5603901EAE13Fdosing.json
      /records/33/existing_route_snapshots/1/route      		Historical; current review incomplete
      H51-EC5D9B9693669FFACFC0BC21dosing.json
      /records/33/existing_route_snapshots/1/population      		Historical; current review incomplete
      H51-F25350E13CBC1D2209CEB1D7dosing.json
      /records/33/existing_route_snapshots/1/indication      		Historical; current review incomplete
      H51-E6598B01BD15F1BC1267642Adosing.json
      /records/33/existing_route_snapshots/1/dose      		Historical; current review incomplete
      H51-FB1CEACBB3C776B78FB4EFC9dosing.json
      /records/33/existing_route_snapshots/1/interval      		Historical; current review incomplete
      H51-E3CCE43B25E77BE759899797dosing.json
      /records/33/existing_route_snapshots/1/duration      		Historical; current review incomplete
      H51-17C449BFEB0515F4370C32A3dosing.json
      /records/33/existing_route_snapshots/1/administration      		Historical; current review incomplete
      H51-BC334E47631DD15BF48E8F90dosing.json
      /records/33/existing_route_snapshots/1/source_level      		Historical; current review incomplete
      H51-521284FFFAD11CA6AAC65340dosing.json
      /records/33/existing_route_snapshots/1/notes      		Historical; current review incomplete
      H51-637AE636BA5438F6CADB251Fdosing.json
      /records/33/existing_route_snapshots/2      		Historical; current review incomplete
      H51-A91A609E91115DC5C9C49D3Fdosing.json
      /records/33/existing_route_snapshots/2/route      		Historical; current review incomplete
      H51-C59B4BCAAA715FAB97F5B8E4dosing.json
      /records/33/existing_route_snapshots/2/population      		Historical; current review incomplete
      H51-20FD116618A4B91E63661F08dosing.json
      /records/33/existing_route_snapshots/2/indication      		Historical; current review incomplete
      H51-B88AA534109E81EA43D17F87dosing.json
      /records/33/existing_route_snapshots/2/dose      		Historical; current review incomplete
      H51-C31E5DB8B2946528AA673FBBdosing.json
      /records/33/existing_route_snapshots/2/interval      		Historical; current review incomplete
      H51-0A3221F7C5CE07788F2D6F14dosing.json
      /records/33/existing_route_snapshots/2/duration      		Historical; current review incomplete
      H51-4249D82CAD4D605E5DAA1890dosing.json
      /records/33/existing_route_snapshots/2/administration      		Historical; current review incomplete
      H51-8F80C36FB07236FE438AA0CBdosing.json
      /records/33/existing_route_snapshots/2/source_level      		Historical; current review incomplete
      H51-3CCFD51DF571C9913C7C9B6Edosing.json
      /records/33/existing_route_snapshots/2/notes      		Historical; current review incomplete
      H51-F638AF8D2DE499B4BB887497dosing.json
      /records/33/clinical_review/locally_normalized      		Historical; current review incomplete
      H51-1A475383691DCE83F4A680AFdosing.json
      /records/33/clinical_review/reviewed      		Historical; current review incomplete
      H51-C9BDC477F3037151AF93DA11dosing.json
      /records/33/clinical_review/status      		Historical; current review incomplete
      H51-7437021DA3EF08BEFB7E1F82dosing.json
      /records/33/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-43827A12501DF891379BD0F6dosing.json
      /records/33/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-3D55D4EB166F02EB4882C5D6dosing.json
      /records/33/clinical_release_verification/level      		Historical; current review incomplete
      H51-E9DEA6146D9198C821F1CF57dosing.json
      /records/33/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-0692C53A45C8117AE25DCE3Adosing.json
      /records/33/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-EF292CAC5AA9A3A145B1F152dosing.json
      /records/33/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-3C7ED6B7BA7255AACE5A6144dosing.json
      /records/33/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-320F5F603501D1FBDB3F026Edosing.json
      /records/33/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-59DE4A7E63E3A1186C060302dosing.json
      /records/33/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-E549A70659DAFFC35982ED36dosing.json
      /records/33/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-18145D3937DF3C6851B2F6B6dosing.json
      /records/33/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-4C51707993F07339C2D29E8Fdosing.json
      /records/33/clinical_release_verification/note      		Historical; current review incomplete
      H51-80D9FE4D60951AE719944A62dosing.json
      /records/33/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-1465B0727C6A0B2833F131FFfirst-look-v5.1.json
      /records/33/id      		Historical; current review incomplete
      H51-A57F9C19A614204C77F3EE4Dfirst-look-v5.1.json
      /records/33/generic_name      		Historical; current review incomplete
      H51-9459166B51E5AFA96781FFAEfirst-look-v5.1.json
      /records/33/class      		Historical; current review incomplete
      H51-1567ED11E6E2B2B1FF807966first-look-v5.1.json
      /records/33/subclass      		Historical; current review incomplete
      H51-90EDE30C0988DB14C43CD594first-look-v5.1.json
      /records/33/primary_uses/0      		Historical; current review incomplete
      H51-C4C7153AF8FE9CCA997D2964first-look-v5.1.json
      /records/33/primary_uses/1      		Historical; current review incomplete
      H51-F69F39F0440DE0B3C7968606first-look-v5.1.json
      /records/33/mechanism      		Historical; current review incomplete
      H51-01B0FCED30CBBFF6481095B4first-look-v5.1.json
      /records/33/mechanism_level      		Historical; current review incomplete
      H51-A68EEB4CB6D0330C588A4833first-look-v5.1.json
      /records/33/basic_dosing_orientation      		Historical; current review incomplete
      H51-0B5F8ED82AFB09108CBFE5DAfirst-look-v5.1.json
      /records/33/administration_orientation      		Historical; current review incomplete
      H51-0BA43A78BEE689F2EDC4D720first-look-v5.1.json
      /records/33/renal_and_population_orientation      		Historical; current review incomplete
      H51-96739A9A251D038F0957FE6Cfirst-look-v5.1.json
      /records/33/key_safety_orientation/0      		Historical; current review incomplete
      H51-EB0FD10FCABF3347FDA000C1first-look-v5.1.json
      /records/33/key_safety_orientation/1      		Historical; current review incomplete
      H51-9CE0394D9221C43515911BD5first-look-v5.1.json
      /records/33/coverage_path      		Historical; current review incomplete
      H51-5FFC11DCFA75365765201F2Cfirst-look-v5.1.json
      /records/33/coverage_path_label      		Historical; current review incomplete
      H51-888156542E0198F8FEAE9056first-look-v5.1.json
      /records/33/official_label_url      		Historical; current review incomplete
      H51-5E153FAB6D7EEAEB3875A0BDfirst-look-v5.1.json
      /records/33/legacy_title      		Historical; current review incomplete
      H51-DC257AD7183D71888F1DC6F8first-look-v5.1.json
      /records/33/review_note      		Historical; current review incomplete
      H51-93CEE2F813E4CFE306CC59D3first-look-v5.1.json
      /records/33/search_text      		Historical; current review incomplete
      H51-643A2FEB1B6736A73E4F6A31first-look-v5.1.json
      /records/33/official_search_url      		Historical; current review incomplete
      H51-3ABBFB6B7398B3D3D1265A66first-look-v5.1.json
      /records/33/official_access_mode      		Historical; current review incomplete
      H51-B689953A3C68184D89D37861first-look-v5.1.json
      /records/33/official_access_url      		Historical; current review incomplete
      H51-83726B76AD693F4B010F06CCfirst-look-v5.1.json
      /records/33/official_search_query      		Historical; current review incomplete
      H51-DF349FC507CEBA26A344A3ECfirst-look-v5.1.json
      /records/33/official_access_reason      		Historical; current review incomplete
      H51-C7DD899F74C7A6D58735C8A7preparation-assessments-v3.8.json
      /33/id      		Historical; current review incomplete
      H51-FFE0EABB6704429FC52EF14Epreparation-assessments-v3.8.json
      /33/name      		Historical; current review incomplete
      H51-4863266BBCF62753C687DD8Apreparation-assessments-v3.8.json
      /33/brands      		Historical; current review incomplete
      H51-EB40E773BCF31F669C099B7Dpreparation-assessments-v3.8.json
      /33/therapeutic_class      		Historical; current review incomplete
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      /33/clinical_release_note      		Historical; current review incomplete
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