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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Medication reference

Pentamidine

Monograph awaiting updateThis monograph will be updated in the future.

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Historical source. Current clinical review is incomplete. This monograph will be updated in the future.

Pentamidine (opens in a new tab)Original source URL: https://globalrph.com/dilution/pentamidine/ | Retrieved 2026-11-04

Source dates, location and integrity

This historical article is separate from the reviewed claim cards. Product formulations and source dates may differ.

Original source URL
https://globalrph.com/dilution/pentamidine/ (opens in a new tab)
Source date
Not established in the retrieved source
Retrieved
2026-11-04T19:47:02.745819+00:00
Source location
div.post-content
Packaged content SHA-256
5a36bef973481621e6e6503e43517280f6a3e41ff3a70d4a8e72e6fb761b7480
Original response SHA-256
6044f8fa803a8cd2ab5cd1ad7503d0e43da49750e0735d86fbe47e3da42db382
Source body SHA-256
58a518d26f005a7780fc6e209df115d15d2330e9cad9c1bbcf49296254d119da

Pentamidine

The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this document shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.

Usual Diluents

D5W

Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]

[0 to 350 mg] [250 ml] [60 min]

Stability / Miscellaneous

EXP: 1 DAY (RT)
Label: Protect from light.

Solutions for injection (1-2.5 mg/mL) in D5W are stable for at least 24
hours at room temperature.

Dosing: PCP: 3 to 4 mg/kg IV qd x 14 - 21 days

Source: [package insert]

Open this historical article on its own

Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • Retrievable exact-product SPL XML with version, revision, retrieval date and reproducible hash
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
current_label_review_required
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.
      Historical first look: uses, mechanism, dosing context, and administration

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      pentamidine
      Source IDH51-F1331EE5847A32A4E6C9E6E1
      Generic name
      Pentamidine
      Source IDH51-134E0050E5A6DAA592DDE8BF
      Class
      Other intravenous medications
      Source IDH51-C40125439400C41F14DB2DD5
      Subclass
      Legacy GlobalRPh directory entry
      Source IDH51-45BB037A42F5661617D21CA5
      Primary uses
      1. A specialized IV indication that requires confirmation in the current exact-product label and applicable specialty guidance.
        Source IDH51-D5240AC736AA463BFD0EA795
      Mechanism
      Interferes with nucleic-acid, protein, phospholipid, and mitochondrial function in susceptible organisms.
      Source IDH51-69E8073A660B8E2585CE7C38
      Mechanism level
      drug_specific
      Source IDH51-7F188ED7EFC3C60036748682
      Basic dosing orientation
      The existing GlobalRPh dose and preparation quick reference loads automatically below. Treat it as historical continuity, then confirm the exact current DailyMed label, population, indication, renal function, and institutional policy.
      Source IDH51-4DD541912DC0E62C1E935122
      Administration orientation
      Route, dilution, concentration, and administration details load automatically from the existing GlobalRPh quick reference below; current exact-product verification remains required.
      Source IDH51-01DA5A93DD689B1B0AA5D59C
      Renal and population orientation
      Separate renal reference: Open Renal Dosing Master (opens in a new tab)Renal dosing status has not been locally normalized; use the current package insert before ordering or administration.
      Source IDH51-D31F8E7F4F8956379E18B13B
      Key safety orientation
      1. Legacy content must be reconciled against current labeling and institutional policy before clinical use.
        Source IDH51-44EBD3C34A2E1AD654FC52A2
      Coverage path
      automatic_legacy_quick_reference
      Source IDH51-3F2EF71ACE27FA61E01ED0C4
      Coverage path label
      Automatic legacy GlobalRPh quick reference
      Source IDH51-3334DE3EA8AA1882CC3B56C7
      Legacy title
      Pentamidine
      Source IDH51-95D63C41A1958745B28C672F
      Review note
      First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
      Source IDH51-A69DBB7E46DD36BF651EB976
      Search text
      Pentamidine Other intravenous medications Legacy GlobalRPh directory entry A specialized IV indication that requires confirmation in the current exact-product label and applicable specialty guidance. Interferes with nucleic-acid, protein, phospholipid, and mitochondrial function in susceptible organisms. The existing GlobalRPh dose and preparation quick reference loads automatically below. Treat it as historical continuity, then confirm the exact current DailyMed label, population, indication, renal function, and institutional policy. Route, dilution, concentration, and administration details load automatically from the existing GlobalRPh quick reference below; current exact-product verification remains required. Renal dosing status has not been locally normalized; use the current package insert before ordering or administration. Legacy content must be reconciled against current labeling and institutional policy before clinical use. Automatic legacy GlobalRPh quick reference
      Source IDH51-F1C22BC3C4BDD4EB8B197BEB
      Official access mode
      none
      Source IDH51-8FAB628EE6134B23454AB739
      Official access reason
      No source-backed DailyMed action has been verified for this umbrella or legacy record; identify the exact product before searching.
      Source IDH51-4C38A9584573F284BF92018B

      No separate structured rows were bundled for preparation, IV push, continuous infusion, population dosing, dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      current_label_review_required
      Source IDH51-A349499E0CE544C514C99C74
      Summary
      Renal dosing status has not been locally normalized; use the current package insert before ordering or administration.
      Source IDH51-1D4E7BDA399885E811C0C81B
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-0716D4DC4C43CF875093EBA1

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Legacy content must be reconciled against current labeling and institutional policy before clinical use.
        Source IDH51-7BDDA2F6940257C45C53F321

      Historical Stability notes

      Recovered v5.1 source content; historical, awaiting current review.

      1. Legacy product stability information is not automatically equivalent to a USP <797> BUD.
        Source IDH51-DAC2C58C1E78DCEABC85CDCA
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      pentamidine
      Source IDH51-72CE0518D8B3B5F393C295D6
      Legacy title
      Pentamidine
      Source IDH51-3F8C2FC1B1BBB4DD5BFEA6A4
      Generic name
      Pentamidine
      Source IDH51-5915B4FBEF1527B0B2A51D7D
      Class
      Other intravenous medications
      Source IDH51-856B48CCFAE9976D3A28B459
      Subclass
      Legacy GlobalRPh directory entry
      Source IDH51-9B0625E813B6CE932BFC4C61
      Summary
      Existing GlobalRPh IV dilution monograph retained for migration into the unified reference.
      Source IDH51-A063E20F8915EF458B1B25D0
      Populations
      1. Population not yet normalized
        Source IDH51-B69316A9C2BE29E624958D9F
      Evidence tier
      Legacy catalog - migration review required
      Source IDH51-AC568FDE20B000E9C7F7BFDA
      High alert
      false
      Source IDH51-8A6DB84E08BB4A4BE61B416D
      Hazardous
      false
      Source IDH51-F81EBFD2B3AB2EC7BF462D17
      Status
      Legacy migration
      Source IDH51-6E0BEDFF4AEDC33E8EDD880C
      Version added
      Legacy
      Source IDH51-270558F7E873AF1198B47A24
      Sources
      LabelUrlKind
      Source IDH51-A591EE603B389F31EE2E7140
      GlobalRPh legacy IV dilution monograph
      Source IDH51-69B54B982A8D483AF2214951
      legacy:auto
      Source IDH51-F8ED60EBC337CEDA8A9857A4
      Legacy
      Source IDH51-2D2AF25BA55AB8FEB582C904
      Clinical release verification
      Audit version
      3.4
      Source IDH51-A426D919C7F04A14ECD50335
      Audited on
      2026-08-30
      Source IDH51-B72F5F1F20EF82798FE222F0
      Level
      red
      Source IDH51-7F40AB30F7B246E7A41DB6BD
      Release gate
      unverified_or_unclassified_sources_do_not_release_as_current
      Source IDH51-40DF7D6E4AF34C5667D94B67
      Exact current label candidate
      false
      Source IDH51-69E5B2E0B823764A7B940EB8
      Reference url count
      0
      Source IDH51-4DF7190526E8410DE261974D
      Broken reference count
      0
      Source IDH51-0991B78DA037C2D5244ADBED
      Point of use confirmation required
      true
      Source IDH51-33A93BD9F778BEF0EEE78629
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-1BAC7DEC7FA96E7A05012AE6

      Dosing source fields

      Id
      pentamidine
      Source IDH51-D46808175E57EADF1CBD0F1D
      Generic name
      Pentamidine
      Source IDH51-15066FC48A4B14381D7331E2
      Coverage status
      direct_official_label_access_plus_legacy_reference
      Source IDH51-7E9A7607B79EBA309EB8CFBF
      Package insert
      Query name
      Pentamidine
      Source IDH51-4099FB39747C96044A2484D0
      Product and route must match
      true
      Source IDH51-8E86837F9389C3E38A51AC7F
      Live current label enabled
      false
      Source IDH51-DC98B4BE5600E6BCE12CA52F
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-EF963D63DDA39646B5309F66
      Direct official label access enabled
      true
      Source IDH51-C262ADE95C9C4EA51C32B772
      Outbound server request required
      false
      Source IDH51-A306B8412B8F19E3490020B5
      Local summary status
      not_bundled
      Source IDH51-F64A40F691F2BF0D19CE2AEF
      Clinical review
      Locally normalized
      false
      Source IDH51-8B28FB02052F4434E5872665
      Reviewed
      2026-08-29
      Source IDH51-B57C286A8580340D74ED1E57
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-93E2B6ED6055F77457205C63
      Clinical release verification
      Audit version
      3.4
      Source IDH51-526FDD22FB871EBE29E15751
      Audited on
      2026-08-30
      Source IDH51-95D0418225AA952FE70ACC86
      Level
      red
      Source IDH51-DA5DB8784007112EF81873DC
      Release gate
      unverified_or_unclassified_sources_do_not_release_as_current
      Source IDH51-C6EADEF6499ADB8F08AE05B7
      Exact current label candidate
      false
      Source IDH51-792FF92F01BAAC7B0E8283E4
      Reference url count
      0
      Source IDH51-BA4D8BFFA80B797F6EF803DE
      Broken reference count
      0
      Source IDH51-4AFD71643441D9B55348E8C1
      Point of use confirmation required
      true
      Source IDH51-EFD64CCC8135B1B44DD124FA
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-F7301B5E35A3D5ACC9AE61ED
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      pentamidine
      Source IDH51-70F107845AE5CA60AEABCB2A
      Name
      Pentamidine
      Source IDH51-10C3B9F6A065D7118AE25723
      Therapeutic class
      Other intravenous medications
      Source IDH51-59AB7A262294071081146A36
      Review version
      3.1
      Source IDH51-8C580450DA184BCAD5D7644C
      Review date
      2026-08-30
      Source IDH51-8D6BD8C31AEC6E50AA36BBE5
      Release status
      no_released_dilution_current_label_review_required
      Source IDH51-9B43A761D4CE5D5D434D600C
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-61CFD3230D3A763BC270A570
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-1E546FC3D827D3E7D3F3CE76
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-5219771E8B53A8E03569BB61
      Reconstitution concentration
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-3076BBCA38781AF9BA7C9106
      Maximum or recommended final concentration
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-7522611F386745DC115916C4
      Appropriate standardized containers
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-09EF0F6F771D4C2CE05E19B9
      Adult dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-EF87A81E491C42EB6665FBFA
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-C8F35C28D637EAB0F820AB50
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-4C00A85BE2138C438CF40FCA
      Infusion time
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-556C243E26DAC96C27E5B2FE
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-4181173C6925C9F8E229BE9F
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-EB8607C8B5ED2FFD18AF8802
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-8ED55D6AF40FDA86F5376A52
      Reconstitution concentration
      Primary
      not_found
      Source IDH51-18849358B12ABE13FF64EA2E
      Maximum or recommended final concentration
      Primary
      not_found
      Source IDH51-09060DCBC46EF3EC9F5E2E11
      Appropriate standardized containers
      Primary
      not_found
      Source IDH51-B7F8953F67AA645DAB286EE4
      Adult dosing range
      Primary
      not_found
      Source IDH51-9B2FB6E4C34FD8520AC5A8CB
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-F5FE910F0D25650EBFE78B62
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-49AE08D0D9BF141B15CDFC93
      Infusion time
      Primary
      not_found
      Source IDH51-4F6FDE8D7C9B73DC72FD6020
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-F51173908A53AD45175C5EA5
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-71316C3CEEC87097CA0D1CA7
      Population applicability
      Adult
      Applicability
      not_established
      Source IDH51-755E5D2864262B20EEB4C2F3
      Guide generation allowed
      false
      Source IDH51-93CC9E3E3C153527405DE6A8
      Pediatric
      Applicability
      not_established
      Source IDH51-15A5A029CD347B08ADEE80F2
      Guide generation allowed
      false
      Source IDH51-9814DB998FC3470B42D48552
      Neonatal
      Applicability
      not_established
      Source IDH51-97FF3C08F6F6602EE162C716
      Guide generation allowed
      false
      Source IDH51-597A46C83138F2D9FE1DA70D
      Route presence
      Structured dilution
      false
      Source IDH51-DF74DF602E3731E70D9E6FE5
      Iv push
      false
      Source IDH51-FA99B90627842190E340C1EF
      Continuous infusion
      false
      Source IDH51-3DD76B48B40B0D6C481B1FEB
      Pediatric source
      false
      Source IDH51-AE47C409BF1CD50135A3CEDC
      Neonatal source
      false
      Source IDH51-12A5C10E9D9372161C8C7953
      Legacy reference
      Status
      not_available
      Source IDH51-A4EF0D4240E6BADF6795A1A4
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-F4833ACA32B5DD98E9557132
      Source files
      1. catalog.json
        Source IDH51-D518CB5587E95B877691AD67
      2. dosing.json
        Source IDH51-EA6301A7624CBB1D98B1BA51
      3. legacy-map.json
        Source IDH51-58D13F709E9D1AFF79C858CD
      4. review-queue.json
        Source IDH51-9F91E206A5F0E160C0E5D967
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-C9C0173BDAF176D2EE41AFEE
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-72CE0518D8B3B5F393C295D6catalog.json
      /records/192/id
      Historical; current review incomplete
      H51-3F8C2FC1B1BBB4DD5BFEA6A4catalog.json
      /records/192/legacy_title
      Historical; current review incomplete
      H51-5915B4FBEF1527B0B2A51D7Dcatalog.json
      /records/192/generic_name
      Historical; current review incomplete
      H51-856B48CCFAE9976D3A28B459catalog.json
      /records/192/class
      Historical; current review incomplete
      H51-9B0625E813B6CE932BFC4C61catalog.json
      /records/192/subclass
      Historical; current review incomplete
      H51-A063E20F8915EF458B1B25D0catalog.json
      /records/192/summary
      Historical; current review incomplete
      H51-7BDDA2F6940257C45C53F321catalog.json
      /records/192/warnings/0
      Historical; current review incomplete
      H51-DAC2C58C1E78DCEABC85CDCAcatalog.json
      /records/192/stability_notes/0
      Historical; current review incomplete
      H51-B69316A9C2BE29E624958D9Fcatalog.json
      /records/192/populations/0
      Historical; current review incomplete
      H51-AC568FDE20B000E9C7F7BFDAcatalog.json
      /records/192/evidence_tier
      Historical; current review incomplete
      H51-8A6DB84E08BB4A4BE61B416Dcatalog.json
      /records/192/high_alert
      Historical; current review incomplete
      H51-F81EBFD2B3AB2EC7BF462D17catalog.json
      /records/192/hazardous
      Historical; current review incomplete
      H51-6E0BEDFF4AEDC33E8EDD880Ccatalog.json
      /records/192/status
      Historical; current review incomplete
      H51-4A4AC8376829C7B1CA8FDCF2catalog.json
      /records/192/reviewed
      Historical; current review incomplete
      H51-270558F7E873AF1198B47A24catalog.json
      /records/192/version_added
      Historical; current review incomplete
      H51-A591EE603B389F31EE2E7140catalog.json
      /records/192/sources/0
      Historical; current review incomplete
      H51-69B54B982A8D483AF2214951catalog.json
      /records/192/sources/0/label
      Historical; current review incomplete
      H51-F8ED60EBC337CEDA8A9857A4catalog.json
      /records/192/sources/0/url
      Historical; current review incomplete
      H51-2D2AF25BA55AB8FEB582C904catalog.json
      /records/192/sources/0/kind
      Historical; current review incomplete
      H51-A426D919C7F04A14ECD50335catalog.json
      /records/192/clinical_release_verification/audit_version
      Historical; current review incomplete
      H51-B72F5F1F20EF82798FE222F0catalog.json
      /records/192/clinical_release_verification/audited_on
      Historical; current review incomplete
      H51-7F40AB30F7B246E7A41DB6BDcatalog.json
      /records/192/clinical_release_verification/level
      Historical; current review incomplete
      H51-40DF7D6E4AF34C5667D94B67catalog.json
      /records/192/clinical_release_verification/release_gate
      Historical; current review incomplete
      H51-69E5B2E0B823764A7B940EB8catalog.json
      /records/192/clinical_release_verification/exact_current_label_candidate
      Historical; current review incomplete
      H51-8B4CEE47CCF56205E2829B75catalog.json
      /records/192/clinical_release_verification/selected_setid
      Historical; current review incomplete
      H51-B5087179BB52B8D92618B5BAcatalog.json
      /records/192/clinical_release_verification/selected_label_title
      Historical; current review incomplete
      H51-29F1D8F619D6622D8091BB1Bcatalog.json
      /records/192/clinical_release_verification/numeric_support_ratio
      Historical; current review incomplete
      H51-4DF7190526E8410DE261974Dcatalog.json
      /records/192/clinical_release_verification/reference_url_count
      Historical; current review incomplete
      H51-0991B78DA037C2D5244ADBEDcatalog.json
      /records/192/clinical_release_verification/broken_reference_count
      Historical; current review incomplete
      H51-33A93BD9F778BEF0EEE78629catalog.json
      /records/192/clinical_release_verification/point_of_use_confirmation_required
      Historical; current review incomplete
      H51-1BAC7DEC7FA96E7A05012AE6catalog.json
      /records/192/clinical_release_verification/note
      Historical; current review incomplete
      H51-57627A268DDE6819A1488051catalog.json
      /records/192/clinical_release_verification/dailymed_search_url
      Historical; current review incomplete
      H51-D46808175E57EADF1CBD0F1Ddosing.json
      /records/192/id
      Historical; current review incomplete
      H51-15066FC48A4B14381D7331E2dosing.json
      /records/192/generic_name
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