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Preparation. Administration. Evidence.

IV Dilution &
Medication Reference

Search 255 medications, read preserved historical references, and inspect separately reviewed preparation statements. Full monograph updates remain pending.

Version 6.4Release date 2026-11-04For healthcare professionals
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Medication reference

Terlipressin

Monograph awaiting updateThis monograph will be updated in the future.

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Selected DailyMed label (opens in a new tab)

No original site article was mapped to this record. The available historical structured fields and official-source links are retained.

Historical first look: uses, mechanism, dosing context, and administration

Recovered v5.1 source content; historical, awaiting current review.

Id
terlipressin
Source IDH51-7684F288397EC9C36BDEACEA
Generic name
Terlipressin
Source IDH51-66C278E93827A1FA89B48900
Class
Cardiovascular and vasoactive
Source IDH51-461C0D83C5131C1A0E26142E
Subclass
Vasopressin analog
Source IDH51-4D8FBE049AF3764451503C4B
Primary uses
  1. Hepatorenal syndrome with rapid reduction in kidney function in adults
    Source IDH51-3FE119111CE53167235A913F
Mechanism
A vasopressin analog whose active metabolites predominantly stimulate V1 receptors and cause vasoconstriction.
Source IDH51-89266BFF5D89195724B204C5
Mechanism level
drug_specific
Source IDH51-A8B083AF63A22B0557BA478E
Basic dosing orientation
Adult | Existing preparation record; use current package insert for indication-specific selection | Label dose schedule adjusted by serum creatinine response | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult | Label-scheduled dose | Label-scheduled dose | Patient- and indication-specific | See current package insert | IV push
Source IDH51-1D266D78DF3E7091E40A2CBE
Administration orientation
Slow IV bolus over approximately 2 minutes; Over about 2 minutes; Reconstituted product concentration; Over about 2 minutes
Source IDH51-8CB966CC4CA97F32AB4155C9
Renal and population orientation
Separate renal reference: Open Renal Dosing Master (opens in a new tab)The existing monograph contains a renal or nephrotoxicity signal; verify exact adjustment and monitoring in the current label.
Source IDH51-2CD4DEF3A54D49DCB30189B0
Key safety orientation
  1. Serious or fatal respiratory failure.
    Source IDH51-4ECCD182972171DA1E36B519
  2. Ischemic events and contraindication in hypoxia or worsening respiratory symptoms.
    Source IDH51-880F20825D569FA9CEF70712
  3. Avoid in patients unlikely to benefit such as very high creatinine or ACLF grade 3 per label.
    Source IDH51-CFDA646729720763323818B4
Coverage path
structured_local_snapshot
Source IDH51-C9E5A07237964390AA404864
Coverage path label
Structured GlobalRPh route snapshot
Source IDH51-2939CC09A5F3D2988D122DFD
Review note
First-look orientation only. Verify indication, patient population, weight basis, organ function, exact IV product, dose, concentration, compatibility, rate, and current labeling before use.
Source IDH51-41F0D5341A5CE79D9F11AAF6
Search text
Terlipressin Cardiovascular and vasoactive Vasopressin analog Hepatorenal syndrome with rapid reduction in kidney function in adults A vasopressin analog whose active metabolites predominantly stimulate V1 receptors and cause vasoconstriction. Adult | Existing preparation record; use current package insert for indication-specific selection | Label dose schedule adjusted by serum creatinine response | Not normalized in the preparation record | See current package insert and professional guidance | IV infusion; Adult | Label-scheduled dose | Label-scheduled dose | Patient- and indication-specific | See current package insert | IV push Slow IV bolus over approximately 2 minutes; Over about 2 minutes; Reconstituted product concentration; Over about 2 minutes The existing monograph contains a renal or nephrotoxicity signal; verify exact adjustment and monitoring in the current label. Serious or fatal respiratory failure. Ischemic events and contraindication in hypoxia or worsening respiratory symptoms. Avoid in patients unlikely to benefit such as very high creatinine or ACLF grade 3 per label. Structured GlobalRPh route snapshot TERLIVAZ TERLIVAZ (terlipressin) injection, powder, lyophilized, for solution DailyMed label snapshot dosage administration dosage forms strengths mechanism
Source IDH51-AC0148A09AFF64E357867DB8
Official access mode
direct_label
Source IDH51-AF47710E784F102171E5FD6E
Official search query
Terlipressin
Source IDH51-2962665036D07B11144B2FE3
Official access reason
Very-high-confidence exact IV product label selected during the v5.1 build-time review. Open the current full DailyMed monograph and verify the stocked product before use.
Source IDH51-65D81CEA743DB1A9C872EE2C
Label snapshot available
true
Source IDH51-ECC2D93154784AEA1678B9C6
Label snapshot setid
3a35b86c-f451-4fac-8499-43019e4da354
Source IDH51-B3B5F6560969EEA9E776F345
Product identifiers and clinical review status

This monograph will be updated in the future. Historical material is available where present in the original sources; full current exact-product and claim-level review remains pending.

Exact formulation, concentration, container, manufacturer, regulatory identifiers, and a reproducible label snapshot have not all been reconciled.

What remains to be completed
  • A retrieved source document is available; clinical reconciliation and a second-source claim map remain incomplete
  • Clinically reviewed, individually identified statements with two exact source mappings
  • Exact formulation, strength, container, manufacturer/labeler, application and NDC reconciliation
  • Renal-function methods and dialysis/CRRT modality review where applicable
  • Mechanism provenance, clinical source disagreements and full medication-specific safety reconciliation

Supplemental historical fields

Restored-data provenance and review notes

Source release: 2026-08-31. Current clinical review is incomplete. Original uses of current, verified, or normalized describe the historical source. They do not inherit the status of separately reviewed statements. Product formulations and source dates can differ.

Current review annotations for historical renal, dialysis, mechanism, and product fieldsSeparate renal reference: Open Renal Dosing Master (opens in a new tab)
Renal
Status
not_locally_normalized
Original classification
renal_review_flagged
Entries
    General note
    Preserve the source-specific renal-function basis. An indexed CrCl table is not interchangeable with unindexed CrCl or eGFR. Generic advice to check a method does not identify the equation for a dose row.
    Dialysis
    Status
    no_local_structured_regimen
    Entries
      General note
      Named modality alone does not establish applicability. CRRT subtype, effluent rate, residual renal function, timing and interruptions require review. Historical absence is not evidence that no guidance exists.
      Mechanisms
      • Source kind
        first_look
        Local pointer
        /mechanism
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Not recorded
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      • Source kind
        label_snapshot
        Local pointer
        /mechanism_summary
        Original level
        drug_specific
        Provenance classification
        historical_drug_specific_uncorroborated
        Label derived verified
        false
        Independently corroborated
        false
        Exact label section
        Not recorded
        Original source note
        Concise GlobalRPh summary reviewed against the selected DailyMed label clinical-pharmacology or microbiology content.
        Review status
        historical_unverified
        Note
        Drug-specific wording in the old file is not proof of independent corroboration or an exact label locator. Consult separately published current mechanism claims where present.
      Future update
      Status
      pending_review
      Message
      This monograph will be updated in the future as current exact-product and claim-level review is completed.
      Source unavailable
      false
      Reason
      The historical content is restored; comprehensive contemporary verification remains incomplete.

      No separate structured rows were bundled for continuous infusion, dialysis, CRRT. Historical article content and source links may cover these topics.

      Historical dilution and intermittent infusion preparation

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      PopulationAmountReconstitutionDiluentFinal volumeConcentrationRateStabilityNotes
      Source IDH51-229063D8B097C5E0893DB3B2
      Adult
      Source IDH51-0D9A730A38CE86029788E842
      		Label dose schedule adjusted by serum creatinine response
      Source IDH51-2922BF2BADBE3FF4F9590A78
      		Reconstitute vial with 5 mL NS to the label concentration.
      Source IDH51-ADB055CBCFDF2AD0AC0ED117
      		May administer reconstituted solution without further dilution
      Source IDH51-AE30F11BE868C67877CF7C32
      		5 mL syringe
      Source IDH51-FA1DBA2384BFCF53D9328359
      		Product-specific
      Source IDH51-5C0034CE0A30CEDDB6456025
      		Slow IV bolus over approximately 2 minutes
      Source IDH51-5F157FCEC9BC8DBB87CB94C5
      		Use the shorter of current product labeling, validated stability data, and the applicable USP <797> sterility-based BUD ceiling.
      Source IDH51-933B7DDC95E43A7133ABF8FC
      		Assess oxygenation and volume status before each dose and follow label stopping rules.
      Source IDH51-6A2B8C2C9074242DD7B3D788

      Historical DailyMed label snapshot

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      terlipressin
      Source IDH51-7D2E490820852A1AEDC481A5
      Catalog name
      Terlipressin
      Source IDH51-69870DDCF06C1F7C58FD648B
      Selection status
      accepted_high_confidence
      Source IDH51-000E6142D7EFBAF1602EC9C8
      Confidence
      very_high
      Source IDH51-DE82D2A93D138C167982D6CB
      Match path
      search_to_exact_label
      Source IDH51-EF72C702D48B3F1D623E65B7
      Brand name
      TERLIVAZ
      Source IDH51-0CC5676E5724125A9317B0A4
      Label title
      TERLIVAZ (terlipressin) injection, powder, lyophilized, for solution
      Source IDH51-3DA5FB028297A0C3BCBAE5F4
      Setid
      3a35b86c-f451-4fac-8499-43019e4da354
      Source IDH51-56D048CCDDE55F2476EB1B59
      Route
      Intermittent slow intravenous bolus
      Source IDH51-F290FF69B1110D52B6F0591A
      Dosage form
      Lyophilized powder for reconstitution
      Source IDH51-83AE3DF405CCFDD58880EA99
      Dosage administration summary
      1. Administer 0.85 mg intravenously every 6 hours on days 1 through 3, then use the day-4 serum-creatinine response algorithm to continue, increase, or discontinue therapy.
        Source IDH51-FD1307EFC1EB13507884104B
      2. Administer as a slow intravenous bolus over approximately 2 minutes and flush the line afterward.
        Source IDH51-3D0CFDECEC5A112302C9F85E
      3. Do not exceed the label-defined treatment duration. Review respiratory-failure risk, oxygenation requirements, ischemic events, and transplant-priority implications.
        Source IDH51-FED0087404B8FF3EEC2758F3
      Dosage forms strengths
      1. 0.85 mg terlipressin lyophilized powder in a single-dose vial
        Source IDH51-A49896B4748344002D157C15
      Mechanism summary
      Terlipressin is a vasopressin analog that produces predominantly V1-receptor-mediated vasoconstriction, increasing effective arterial volume in hepatorenal syndrome.
      Source IDH51-2D254EED68F9720C641F1504
      Scope note
      Selected TERLIVAZ label for adults with hepatorenal syndrome and rapidly worsening renal function.
      Source IDH51-F912C7B98E33C7CD82F055DE
      Reviewed on
      2026-08-31
      Source IDH51-1E446D08768C818B7A1AD682
      Mechanism source
      Concise GlobalRPh summary reviewed against the selected DailyMed label clinical-pharmacology or microbiology content.
      Source IDH51-040BF8FB361782AAE3C5C515
      Source sections
      1. Dosage and Administration
        Source IDH51-BB36E4EA50449354E2E6FBF7
      2. Dosage Forms and Strengths
        Source IDH51-469FE17D281AF838B3ED6FA9
      3. Clinical Pharmacology or Microbiology as applicable
        Source IDH51-1B974A013BEF985A89A4072A
      Retrieval method
      Manual build-time review of the current DailyMed full prescribing information for the selected Set ID; no live server retrieval is required during page use.
      Source IDH51-53F728123809F063272AFEF9
      Label status
      current
      Source IDH51-27B6F8B9FD75C4A32A2BB5DC
      Disclaimer
      Verify the exact formulation, strength, manufacturer, NDC, route, current label revision, patient-specific order, institutional policy, and monitoring before use.
      Source IDH51-0500052B912ECE44800A7E0D

      Historical IV-push guidance

      Recovered v5.1 source content; historical, awaiting current review.

      PopulationDose scopeConcentrationRateStatus
      Source IDH51-2361F9D8E80BEF974FB803CC
      Adult
      Source IDH51-3A6B2D3DB5CC7388CE08AF19
      		Label-scheduled dose
      Source IDH51-27A3AF150D798FE8EBCA5CEE
      		Reconstituted product concentration
      Source IDH51-97BEB9D6BF8EF212EAD4ECEF
      		Over about 2 minutes
      Source IDH51-3EBBFAD73B3A79ECE0557D2E
      		Label-standard with strict eligibility and monitoring
      Source IDH51-92B210AB4E9723536202E48B

      Historical indication and population dosing

      Recovered tables and source-separated snapshots; full clinical revalidation remains pending.

      Existing dose and route snapshots

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      RoutePopulationIndicationDoseIntervalDurationAdministrationSource levelNotes
      Source IDH51-B3FE34F9EFBB3E2225DB2BCB
      IV infusion
      Source IDH51-B0E82FAD0807C522103F291E
      		Adult
      Source IDH51-7C5954D85ACBD14EE38DC4C6
      		Existing preparation record; use current package insert for indication-specific selection
      Source IDH51-4FB709921A43D69E37FE4D30
      		Label dose schedule adjusted by serum creatinine response
      Source IDH51-4189DBC847C08A1DD75D20B0
      		Not normalized in the preparation record
      Source IDH51-42974E81C00730664B09737C
      		See current package insert and professional guidance
      Source IDH51-465E03EEAC62F34219795A26
      		Slow IV bolus over approximately 2 minutes
      Source IDH51-4E0F7828A7A73BC9A4456250
      		Existing GlobalRPh structured preparation snapshot
      Source IDH51-3064A25BEAAF0F080077B2C7
      		Assess oxygenation and volume status before each dose and follow label stopping rules.
      Source IDH51-EBA9CFDDAEEE93CBE9189240
      Source IDH51-D833443F368C3865FD8902E2
      IV push
      Source IDH51-A60137441007F9F78FB60A35
      		Adult
      Source IDH51-ECF321C74D1B131CFFB066A3
      		Label-scheduled dose
      Source IDH51-1FD81C1B8F93A947D90FF694
      		Label-scheduled dose
      Source IDH51-02A09A59C1D1E23495FA32B1
      		Patient- and indication-specific
      Source IDH51-D34E074DC64CD8923DC35F6C
      		See current package insert
      Source IDH51-04D9A07F55D08A7B16319739
      		Over about 2 minutes
      Source IDH51-F24C1937000163753745CBFB
      		Existing GlobalRPh IV push snapshot
      Source IDH51-DECE9A6160E96A3D2461695A
      		Label-standard with strict eligibility and monitoring
      Source IDH51-0B7F5BD34887A62B3CC699F8

      Historical renal-function guidance

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      Classification
      renal_review_flagged
      Source IDH51-18297F0258F5B4753A5A9512
      Summary
      The existing monograph contains a renal or nephrotoxicity signal; verify exact adjustment and monitoring in the current label.
      Source IDH51-12F62F8DDC994831F4ED12BD
      Method note
      Use the renal function estimate and body-size convention specified by the selected label or institutional protocol. Do not interchange Cockcroft-Gault CrCl, indexed eGFR, and de-indexed eGFR without confirming the dosing source.
      Source IDH51-DEBA4F0B6690B404FDA6EC9A

      Historical Common IV uses

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      1. Hepatorenal syndrome with rapid reduction in kidney function in adults
        Source IDH51-739366599767462F076A8510

      Historical Warnings and safeguards

      Recovered v5.1 source content; historical, awaiting current review.

      1. Serious or fatal respiratory failure.
        Source IDH51-1B28AD6FBF9A025B181B4730
      2. Ischemic events and contraindication in hypoxia or worsening respiratory symptoms.
        Source IDH51-CF74D9A71715BA9B2888185C
      3. Avoid in patients unlikely to benefit such as very high creatinine or ACLF grade 3 per label.
        Source IDH51-29A5EA1F26FB7BAAD7F10501

      Historical Monitoring

      Recovered v5.1 source content; historical, awaiting current review.

      Separate renal reference: Open Renal Dosing Master (opens in a new tab)
      1. Continuous or frequent oxygen saturation
        Source IDH51-823EB5955443A735E3DE9E0A
      2. Respiratory status and volume overload
        Source IDH51-50D932589A65AC8FAEDC871B
      3. Serum creatinine and ischemic symptoms
        Source IDH51-433B08DF3F99A4368DF146BA
      Other recovered source fields and original editorial metadata

      Original status words such as current, verified, or normalized describe the historical source release. They do not change the clinical review status of this release.

      Catalog source fields

      Id
      terlipressin
      Source IDH51-F5C2C328BA8427D4D869AA5B
      Generic name
      Terlipressin
      Source IDH51-DF6B95A28B5A556F2EAB762A
      Brand names
      1. Terlivaz
        Source IDH51-E6BDAFA02DD0F745776E3458
      Class
      Cardiovascular and vasoactive
      Source IDH51-6235AFCA2D2185496AEB627F
      Subclass
      Vasopressin analog
      Source IDH51-152769C3B6819B1DD6AD2CCE
      Summary
      Vasopressin analog administered by scheduled IV bolus for hepatorenal syndrome; respiratory failure and ischemia are major safety concerns.
      Source IDH51-8FA4C7D62CB3C7FC9DA36FA4
      Populations
      1. Adult
        Source IDH51-F20DD84146D6B0DCB7675FC0
      Evidence tier
      Core reference - verify current label
      Source IDH51-41C6EEC69564EF200C0ED184
      High alert
      true
      Source IDH51-A0C9E849A282AEC28DA97642
      Hazardous
      false
      Source IDH51-7CC40E230725D1105436AADA
      Status
      Active
      Source IDH51-9B392D5171BF1E23CE6F6F1B
      Reviewed
      2026-08-29
      Source IDH51-79DA5E1919DF81A0549A6342
      Version added
      1.2
      Source IDH51-CFA6700295C521332BC56731
      Sources
      LabelUrlKind
      Source IDH51-26641056759B08A3F9A39CED
      DailyMed label search
      Source IDH51-CB722F3229E48D2B4F503C45
      		https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Terlipressin (opens in a new tab)
      Source IDH51-1608BAC1A2278B5341EA96D2
      		Primary
      Source IDH51-213A8A49E1DF45C61F3037B1
      Source IDH51-85714481656C9C7635D599B1
      GlobalRPh legacy IV dilution monograph
      Source IDH51-D22C128343ECB630394B5A64
      		legacy:auto
      Source IDH51-4F852F33DA625A9F81F94E30
      		Legacy
      Source IDH51-CEB870F5ED70B05884DAF6E4
      Clinical release verification
      Audit version
      3.4
      Source IDH51-EEC717B196D41C4F6DA7DA4E
      Audited on
      2026-08-30
      Source IDH51-BC2C0746E4ECFF839A0A5E0C
      Level
      amber
      Source IDH51-617CA40CA5E044A909497621
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-DF91ACCA2A4DB1042211281F
      Exact current label candidate
      false
      Source IDH51-40ECDEB4EB8493A632E13808
      Numeric support ratio
      0
      Source IDH51-0A9AE7D7EA4CF5E2C92DC759
      Reference url count
      1
      Source IDH51-E26CEC529974DA47C0FF702A
      Broken reference count
      0
      Source IDH51-C3844C13EF6383C9589430B6
      Point of use confirmation required
      true
      Source IDH51-F479B4E88CEA988335AF5209
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-2D23D39E6147C13F105B3219
      Version updated
      5.1
      Source IDH51-C96FAD644B7AF82694A48CDF

      Dosing source fields

      Id
      terlipressin
      Source IDH51-B472F5AE8DBEE3885B866340
      Generic name
      Terlipressin
      Source IDH51-3174178CE1BF020E1AA6DEAE
      Coverage status
      direct_official_label_access_plus_local_snapshot
      Source IDH51-A030D4F5649AD13953691655
      Package insert
      Query name
      Terlipressin
      Source IDH51-29C236762DC4909C0A332CDD
      Product and route must match
      true
      Source IDH51-4E32B97EE59F64F520109184
      Live current label enabled
      false
      Source IDH51-373F3B9E0F47F28FA318ECCD
      Source priority
      Reviewed local summary when available, then a verified DailyMed label or product search when available, followed by professional references and institutional policy.
      Source IDH51-5D3E442FBFF94F42726BD683
      Direct official label access enabled
      true
      Source IDH51-1B28E2152ECE2FC8CD0A4CD5
      Outbound server request required
      false
      Source IDH51-DE8396C517A4E9BD2CA45A31
      Local summary status
      not_bundled
      Source IDH51-5297E6BB324BC59FD3B5D415
      Clinical review
      Locally normalized
      false
      Source IDH51-C946CFA08AEEA63E20EF2194
      Reviewed
      2026-08-29
      Source IDH51-0EED77D13BD5918F3C6E8EE3
      Status
      Direct official package-insert access enabled; indication-specific local normalization pending.
      Source IDH51-D92B0CBB0506ECF4E84591F5
      Clinical release verification
      Audit version
      3.4
      Source IDH51-30DB2EA0DCD54436058776ED
      Audited on
      2026-08-30
      Source IDH51-8ADC375FBC42B623B494FB3A
      Level
      amber
      Source IDH51-DAFEB1DD1DEFD84E6E746741
      Release gate
      trusted_professional_source_present_exact_label_unconfirmed
      Source IDH51-4035A5B60D5B555B09999A0F
      Exact current label candidate
      false
      Source IDH51-F2C85E442635D41891DBA803
      Numeric support ratio
      0
      Source IDH51-BD22B8DABAE65F259BA04DC1
      Reference url count
      1
      Source IDH51-2DB38C7A7571BEDA84C9919F
      Broken reference count
      0
      Source IDH51-A310F1D751EA0B5E0FCB2709
      Point of use confirmation required
      true
      Source IDH51-2B6E55DFE1C16820B53A2EAA
      Note
      Do not treat this record as a fully current product-specific monograph until the exact IV formulation and current sources are confirmed.
      Source IDH51-39A119F19F88F5FA5E85832C
      Historical preparation assessment

      Recovered v5.1 source content; historical, awaiting current review.

      Id
      terlipressin
      Source IDH51-521FFA1FC641FB2885C313D7
      Name
      Terlipressin
      Source IDH51-FA9FFAD980BF4C581A5CEFC5
      Brands
      Terlivaz
      Source IDH51-B8CD722D4286949BD7F1E1B2
      Therapeutic class
      Cardiovascular and vasoactive
      Source IDH51-4E0EC38A20F4B4ED28B986B0
      Review version
      3.1
      Source IDH51-FE12D86FE74B502097DD3965
      Review date
      2026-08-30
      Source IDH51-0B714040E45E1CB68B27FD65
      Release status
      structured_record_current_label_not_confirmed
      Source IDH51-4969DFD01960ED125C107BD6
      Market status
      Status
      no_current_us_iv_spl_confirmed
      Source IDH51-F30BD2257CA79F8F9DBC490D
      Basis
      No high-confidence current IV SPL was automatically selected; legacy information is segregated
      Source IDH51-8E2B4F29820671858C0EF3FA
      Ten point assessment
      Exact formulation
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-3EBDAD452E154E564B606306
      Reconstitution concentration
      Reconstitute vial with 5 mL NS to the label concentration.
      Source IDH51-CB0AB9181596EC073E779CD2
      Maximum or recommended final concentration
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-6EB20FB3AC851AFD5F5F97DB
      Appropriate standardized containers
      5 mL syringe
      Source IDH51-FFA0319C14291C3D819E2D78
      Adult dosing range
      Separate renal reference: Open Renal Dosing Master (opens in a new tab)Label dose schedule adjusted by serum creatinine response Label-scheduled dose Label-scheduled dose
      Source IDH51-137A1FAE0F3A9A0780EE0D45
      Pediatric dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-408ED9C0FCD2BD9FA9E50B5F
      Neonatal dosing range
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-6D43B7B9132079A3BFC6911C
      Infusion time
      Slow IV bolus over approximately 2 minutes Over about 2 minutes
      Source IDH51-671EF913F6BD76E2E411F530
      Fluid restriction alternatives
      Not established in the currently normalized record. Use the current-label panel before clinical use.
      Source IDH51-CC6B53DB788A4F5493A0AABE
      Current manufacturer labeling
      Match confidence
      unresolved
      Source IDH51-C4C5B0678A75EFCFA9F054E8
      Field provenance
      Exact formulation
      Primary
      not_found
      Source IDH51-FBBD6670159C0100187153DE
      Reconstitution concentration
      Primary
      existing_structured_record
      Source IDH51-921BE839C085C826C24F0BB7
      Maximum or recommended final concentration
      Primary
      not_found
      Source IDH51-AED8B5C249DE6FB4B0BF6B81
      Appropriate standardized containers
      Primary
      existing_structured_record
      Source IDH51-7ACAD0744B4FB9DA0229B5FD
      Adult dosing range
      Primary
      existing_structured_record
      Source IDH51-D02299349183398BEE686715
      Pediatric dosing range
      Primary
      not_found
      Source IDH51-3188EAB3D822962C717FF754
      Neonatal dosing range
      Primary
      not_found
      Source IDH51-BFA95F75D626275642909C17
      Infusion time
      Primary
      existing_structured_record
      Source IDH51-A647F18C253B6A3022AA84CB
      Fluid restriction alternatives
      Primary
      not_found
      Source IDH51-A4AC99F78B75281F97921BD7
      Current manufacturer labeling
      Primary
      DailyMed search gateway
      Source IDH51-82D3FE89DA1C50F518AB05B7
      Population applicability
      Adult
      Applicability
      supported_or_source_present
      Source IDH51-4DB1C3E9D243378BAEDCD271
      Guide generation allowed
      true
      Source IDH51-5FC94C073414C9B027E03D51
      Pediatric
      Applicability
      not_established
      Source IDH51-26BAD9B9F7D2019EA5902998
      Guide generation allowed
      false
      Source IDH51-43CE4E78AA72C314B1F89A86
      Neonatal
      Applicability
      not_established
      Source IDH51-B665342AA18125492C9C7860
      Guide generation allowed
      false
      Source IDH51-0D6082EBEA872218352AD274
      Route presence
      Structured dilution
      true
      Source IDH51-A183FF94D9BC691FAF949FDC
      Iv push
      true
      Source IDH51-7874B1EB89C71E5499E65247
      Continuous infusion
      false
      Source IDH51-B0D6C9265C217AF6DDB0EC3D
      Pediatric source
      false
      Source IDH51-B5263BB8435525BBB27C3F94
      Neonatal source
      false
      Source IDH51-CE39D78E468C4ACEBC2993EC
      Legacy reference
      Status
      not_available
      Source IDH51-E6BDB7973411FD40A2CB1E01
      Label resolution
      Status
      build_environment_network_unavailable
      Source IDH51-9CFB861E161D0E52A56929A8
      Source files
      1. catalog.json
        Source IDH51-A7B9F25B98E44E9098632444
      2. dosing.json
        Source IDH51-251A4A4D00A1F457EA616D1A
      3. new-in-v1.2.json
        Source IDH51-B98164D6EA73D73A8B9BDD83
      Clinical release note
      Preparation instructions are released only at the evidence level shown. Legacy content remains visibly separate. Exact product, NDC, route, current labeling, and institutional policy must be confirmed.
      Source IDH51-D80FD82364E460CB7D2E797D
      Historical statement IDs and source locations

      These IDs identify recovered source units. They are not evidence-qualified clinical claims.

      Historical IDOriginal source locationStatus
      H51-F5C2C328BA8427D4D869AA5Bcatalog.json
      /records/235/id      		Historical; current review incomplete
      H51-DF6B95A28B5A556F2EAB762Acatalog.json
      /records/235/generic_name      		Historical; current review incomplete
      H51-E6BDAFA02DD0F745776E3458catalog.json
      /records/235/brand_names/0      		Historical; current review incomplete
      H51-6235AFCA2D2185496AEB627Fcatalog.json
      /records/235/class      		Historical; current review incomplete
      H51-152769C3B6819B1DD6AD2CCEcatalog.json
      /records/235/subclass      		Historical; current review incomplete
      H51-8FA4C7D62CB3C7FC9DA36FA4catalog.json
      /records/235/summary      		Historical; current review incomplete
      H51-739366599767462F076A8510catalog.json
      /records/235/common_uses/0      		Historical; current review incomplete
      H51-229063D8B097C5E0893DB3B2catalog.json
      /records/235/preparations/0      		Historical; current review incomplete
      H51-0D9A730A38CE86029788E842catalog.json
      /records/235/preparations/0/population      		Historical; current review incomplete
      H51-2922BF2BADBE3FF4F9590A78catalog.json
      /records/235/preparations/0/amount      		Historical; current review incomplete
      H51-ADB055CBCFDF2AD0AC0ED117catalog.json
      /records/235/preparations/0/reconstitution      		Historical; current review incomplete
      H51-AE30F11BE868C67877CF7C32catalog.json
      /records/235/preparations/0/diluent      		Historical; current review incomplete
      H51-FA1DBA2384BFCF53D9328359catalog.json
      /records/235/preparations/0/final_volume      		Historical; current review incomplete
      H51-5C0034CE0A30CEDDB6456025catalog.json
      /records/235/preparations/0/concentration      		Historical; current review incomplete
      H51-5F157FCEC9BC8DBB87CB94C5catalog.json
      /records/235/preparations/0/rate      		Historical; current review incomplete
      H51-933B7DDC95E43A7133ABF8FCcatalog.json
      /records/235/preparations/0/stability      		Historical; current review incomplete
      H51-6A2B8C2C9074242DD7B3D788catalog.json
      /records/235/preparations/0/notes      		Historical; current review incomplete
      H51-2361F9D8E80BEF974FB803CCcatalog.json
      /records/235/iv_push/0      		Historical; current review incomplete
      H51-3A6B2D3DB5CC7388CE08AF19catalog.json
      /records/235/iv_push/0/population      		Historical; current review incomplete
      H51-27A3AF150D798FE8EBCA5CEEcatalog.json
      /records/235/iv_push/0/dose_scope      		Historical; current review incomplete
      H51-97BEB9D6BF8EF212EAD4ECEFcatalog.json
      /records/235/iv_push/0/concentration      		Historical; current review incomplete
      H51-3EBBFAD73B3A79ECE0557D2Ecatalog.json
      /records/235/iv_push/0/rate      		Historical; current review incomplete
      H51-92B210AB4E9723536202E48Bcatalog.json
      /records/235/iv_push/0/status      		Historical; current review incomplete
      H51-241FADD099C9A6D9952ED922catalog.json
      /records/235/iv_push/0/notes      		Historical; current review incomplete
      H51-1B28AD6FBF9A025B181B4730catalog.json
      /records/235/warnings/0      		Historical; current review incomplete
      H51-CF74D9A71715BA9B2888185Ccatalog.json
      /records/235/warnings/1      		Historical; current review incomplete
      H51-29A5EA1F26FB7BAAD7F10501catalog.json
      /records/235/warnings/2      		Historical; current review incomplete
      H51-823EB5955443A735E3DE9E0Acatalog.json
      /records/235/monitoring/0      		Historical; current review incomplete
      H51-50D932589A65AC8FAEDC871Bcatalog.json
      /records/235/monitoring/1      		Historical; current review incomplete
      H51-433B08DF3F99A4368DF146BAcatalog.json
      /records/235/monitoring/2      		Historical; current review incomplete
      H51-F20DD84146D6B0DCB7675FC0catalog.json
      /records/235/populations/0      		Historical; current review incomplete
      H51-41C6EEC69564EF200C0ED184catalog.json
      /records/235/evidence_tier      		Historical; current review incomplete
      H51-A0C9E849A282AEC28DA97642catalog.json
      /records/235/high_alert      		Historical; current review incomplete
      H51-7CC40E230725D1105436AADAcatalog.json
      /records/235/hazardous      		Historical; current review incomplete
      H51-9B392D5171BF1E23CE6F6F1Bcatalog.json
      /records/235/status      		Historical; current review incomplete
      H51-79DA5E1919DF81A0549A6342catalog.json
      /records/235/reviewed      		Historical; current review incomplete
      H51-CFA6700295C521332BC56731catalog.json
      /records/235/version_added      		Historical; current review incomplete
      H51-26641056759B08A3F9A39CEDcatalog.json
      /records/235/sources/0      		Historical; current review incomplete
      H51-CB722F3229E48D2B4F503C45catalog.json
      /records/235/sources/0/label      		Historical; current review incomplete
      H51-1608BAC1A2278B5341EA96D2catalog.json
      /records/235/sources/0/url      		Historical; current review incomplete
      H51-213A8A49E1DF45C61F3037B1catalog.json
      /records/235/sources/0/kind      		Historical; current review incomplete
      H51-85714481656C9C7635D599B1catalog.json
      /records/235/sources/1      		Historical; current review incomplete
      H51-D22C128343ECB630394B5A64catalog.json
      /records/235/sources/1/label      		Historical; current review incomplete
      H51-4F852F33DA625A9F81F94E30catalog.json
      /records/235/sources/1/url      		Historical; current review incomplete
      H51-CEB870F5ED70B05884DAF6E4catalog.json
      /records/235/sources/1/kind      		Historical; current review incomplete
      H51-46153F36CB5DA4BC7A8BFC30catalog.json
      /records/235/legacy_title      		Historical; current review incomplete
      H51-EEC717B196D41C4F6DA7DA4Ecatalog.json
      /records/235/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-BC2C0746E4ECFF839A0A5E0Ccatalog.json
      /records/235/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-617CA40CA5E044A909497621catalog.json
      /records/235/clinical_release_verification/level      		Historical; current review incomplete
      H51-DF91ACCA2A4DB1042211281Fcatalog.json
      /records/235/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-40ECDEB4EB8493A632E13808catalog.json
      /records/235/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-FE10A1699D23E1E1F1C03DE8catalog.json
      /records/235/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-D4C4AA85172C7A00F3CD5D3Fcatalog.json
      /records/235/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-0A9AE7D7EA4CF5E2C92DC759catalog.json
      /records/235/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-E26CEC529974DA47C0FF702Acatalog.json
      /records/235/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-C3844C13EF6383C9589430B6catalog.json
      /records/235/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-F479B4E88CEA988335AF5209catalog.json
      /records/235/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-2D23D39E6147C13F105B3219catalog.json
      /records/235/clinical_release_verification/note      		Historical; current review incomplete
      H51-5AF9BAD98841A96D95A2B3CBcatalog.json
      /records/235/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-C96FAD644B7AF82694A48CDFcatalog.json
      /records/235/version_updated      		Historical; current review incomplete
      H51-7D2E490820852A1AEDC481A5dailymed-label-snapshots-v5.1.json
      /records/46/id      		Historical; current review incomplete
      H51-69870DDCF06C1F7C58FD648Bdailymed-label-snapshots-v5.1.json
      /records/46/catalog_name      		Historical; current review incomplete
      H51-000E6142D7EFBAF1602EC9C8dailymed-label-snapshots-v5.1.json
      /records/46/selection_status      		Historical; current review incomplete
      H51-DE82D2A93D138C167982D6CBdailymed-label-snapshots-v5.1.json
      /records/46/confidence      		Historical; current review incomplete
      H51-EF72C702D48B3F1D623E65B7dailymed-label-snapshots-v5.1.json
      /records/46/match_path      		Historical; current review incomplete
      H51-0CC5676E5724125A9317B0A4dailymed-label-snapshots-v5.1.json
      /records/46/brand_name      		Historical; current review incomplete
      H51-3DA5FB028297A0C3BCBAE5F4dailymed-label-snapshots-v5.1.json
      /records/46/label_title      		Historical; current review incomplete
      H51-56D048CCDDE55F2476EB1B59dailymed-label-snapshots-v5.1.json
      /records/46/setid      		Historical; current review incomplete
      H51-F290FF69B1110D52B6F0591Adailymed-label-snapshots-v5.1.json
      /records/46/route      		Historical; current review incomplete
      H51-83AE3DF405CCFDD58880EA99dailymed-label-snapshots-v5.1.json
      /records/46/dosage_form      		Historical; current review incomplete
      H51-FD1307EFC1EB13507884104Bdailymed-label-snapshots-v5.1.json
      /records/46/dosage_administration_summary/0      		Historical; current review incomplete
      H51-3D0CFDECEC5A112302C9F85Edailymed-label-snapshots-v5.1.json
      /records/46/dosage_administration_summary/1      		Historical; current review incomplete
      H51-FED0087404B8FF3EEC2758F3dailymed-label-snapshots-v5.1.json
      /records/46/dosage_administration_summary/2      		Historical; current review incomplete
      H51-A49896B4748344002D157C15dailymed-label-snapshots-v5.1.json
      /records/46/dosage_forms_strengths/0      		Historical; current review incomplete
      H51-2D254EED68F9720C641F1504dailymed-label-snapshots-v5.1.json
      /records/46/mechanism_summary      		Historical; current review incomplete
      H51-F912C7B98E33C7CD82F055DEdailymed-label-snapshots-v5.1.json
      /records/46/scope_note      		Historical; current review incomplete
      H51-1FE2BDAB7394C18B2C22717Ddailymed-label-snapshots-v5.1.json
      /records/46/labeler      		Historical; current review incomplete
      H51-F2A000B91C44A8AA8A3822F0dailymed-label-snapshots-v5.1.json
      /records/46/official_label_url      		Historical; current review incomplete
      H51-1E446D08768C818B7A1AD682dailymed-label-snapshots-v5.1.json
      /records/46/reviewed_on      		Historical; current review incomplete
      H51-040BF8FB361782AAE3C5C515dailymed-label-snapshots-v5.1.json
      /records/46/mechanism_source      		Historical; current review incomplete
      H51-BB36E4EA50449354E2E6FBF7dailymed-label-snapshots-v5.1.json
      /records/46/source_sections/0      		Historical; current review incomplete
      H51-469FE17D281AF838B3ED6FA9dailymed-label-snapshots-v5.1.json
      /records/46/source_sections/1      		Historical; current review incomplete
      H51-1B974A013BEF985A89A4072Adailymed-label-snapshots-v5.1.json
      /records/46/source_sections/2      		Historical; current review incomplete
      H51-53F728123809F063272AFEF9dailymed-label-snapshots-v5.1.json
      /records/46/retrieval_method      		Historical; current review incomplete
      H51-27B6F8B9FD75C4A32A2BB5DCdailymed-label-snapshots-v5.1.json
      /records/46/label_status      		Historical; current review incomplete
      H51-0500052B912ECE44800A7E0Ddailymed-label-snapshots-v5.1.json
      /records/46/disclaimer      		Historical; current review incomplete
      H51-B472F5AE8DBEE3885B866340dosing.json
      /records/235/id      		Historical; current review incomplete
      H51-3174178CE1BF020E1AA6DEAEdosing.json
      /records/235/generic_name      		Historical; current review incomplete
      H51-A030D4F5649AD13953691655dosing.json
      /records/235/coverage_status      		Historical; current review incomplete
      H51-29C236762DC4909C0A332CDDdosing.json
      /records/235/package_insert/query_name      		Historical; current review incomplete
      H51-B5D474908A6DAAB6A914F612dosing.json
      /records/235/package_insert/preferred_setid      		Historical; current review incomplete
      H51-4E32B97EE59F64F520109184dosing.json
      /records/235/package_insert/product_and_route_must_match      		Historical; current review incomplete
      H51-373F3B9E0F47F28FA318ECCDdosing.json
      /records/235/package_insert/live_current_label_enabled      		Historical; current review incomplete
      H51-5D3E442FBFF94F42726BD683dosing.json
      /records/235/package_insert/source_priority      		Historical; current review incomplete
      H51-1B28E2152ECE2FC8CD0A4CD5dosing.json
      /records/235/package_insert/direct_official_label_access_enabled      		Historical; current review incomplete
      H51-DE8396C517A4E9BD2CA45A31dosing.json
      /records/235/package_insert/outbound_server_request_required      		Historical; current review incomplete
      H51-5297E6BB324BC59FD3B5D415dosing.json
      /records/235/package_insert/local_summary_status      		Historical; current review incomplete
      H51-18297F0258F5B4753A5A9512dosing.json
      /records/235/renal/classification      		Historical; current review incomplete
      H51-12F62F8DDC994831F4ED12BDdosing.json
      /records/235/renal/summary      		Historical; current review incomplete
      H51-DEBA4F0B6690B404FDA6EC9Adosing.json
      /records/235/renal/method_note      		Historical; current review incomplete
      H51-B3FE34F9EFBB3E2225DB2BCBdosing.json
      /records/235/existing_route_snapshots/0      		Historical; current review incomplete
      H51-B0E82FAD0807C522103F291Edosing.json
      /records/235/existing_route_snapshots/0/route      		Historical; current review incomplete
      H51-7C5954D85ACBD14EE38DC4C6dosing.json
      /records/235/existing_route_snapshots/0/population      		Historical; current review incomplete
      H51-4FB709921A43D69E37FE4D30dosing.json
      /records/235/existing_route_snapshots/0/indication      		Historical; current review incomplete
      H51-4189DBC847C08A1DD75D20B0dosing.json
      /records/235/existing_route_snapshots/0/dose      		Historical; current review incomplete
      H51-42974E81C00730664B09737Cdosing.json
      /records/235/existing_route_snapshots/0/interval      		Historical; current review incomplete
      H51-465E03EEAC62F34219795A26dosing.json
      /records/235/existing_route_snapshots/0/duration      		Historical; current review incomplete
      H51-4E0F7828A7A73BC9A4456250dosing.json
      /records/235/existing_route_snapshots/0/administration      		Historical; current review incomplete
      H51-3064A25BEAAF0F080077B2C7dosing.json
      /records/235/existing_route_snapshots/0/source_level      		Historical; current review incomplete
      H51-EBA9CFDDAEEE93CBE9189240dosing.json
      /records/235/existing_route_snapshots/0/notes      		Historical; current review incomplete
      H51-D833443F368C3865FD8902E2dosing.json
      /records/235/existing_route_snapshots/1      		Historical; current review incomplete
      H51-A60137441007F9F78FB60A35dosing.json
      /records/235/existing_route_snapshots/1/route      		Historical; current review incomplete
      H51-ECF321C74D1B131CFFB066A3dosing.json
      /records/235/existing_route_snapshots/1/population      		Historical; current review incomplete
      H51-1FD81C1B8F93A947D90FF694dosing.json
      /records/235/existing_route_snapshots/1/indication      		Historical; current review incomplete
      H51-02A09A59C1D1E23495FA32B1dosing.json
      /records/235/existing_route_snapshots/1/dose      		Historical; current review incomplete
      H51-D34E074DC64CD8923DC35F6Cdosing.json
      /records/235/existing_route_snapshots/1/interval      		Historical; current review incomplete
      H51-04D9A07F55D08A7B16319739dosing.json
      /records/235/existing_route_snapshots/1/duration      		Historical; current review incomplete
      H51-F24C1937000163753745CBFBdosing.json
      /records/235/existing_route_snapshots/1/administration      		Historical; current review incomplete
      H51-DECE9A6160E96A3D2461695Adosing.json
      /records/235/existing_route_snapshots/1/source_level      		Historical; current review incomplete
      H51-0B7F5BD34887A62B3CC699F8dosing.json
      /records/235/existing_route_snapshots/1/notes      		Historical; current review incomplete
      H51-C946CFA08AEEA63E20EF2194dosing.json
      /records/235/clinical_review/locally_normalized      		Historical; current review incomplete
      H51-0EED77D13BD5918F3C6E8EE3dosing.json
      /records/235/clinical_review/reviewed      		Historical; current review incomplete
      H51-D92B0CBB0506ECF4E84591F5dosing.json
      /records/235/clinical_review/status      		Historical; current review incomplete
      H51-30DB2EA0DCD54436058776EDdosing.json
      /records/235/clinical_release_verification/audit_version      		Historical; current review incomplete
      H51-8ADC375FBC42B623B494FB3Adosing.json
      /records/235/clinical_release_verification/audited_on      		Historical; current review incomplete
      H51-DAFEB1DD1DEFD84E6E746741dosing.json
      /records/235/clinical_release_verification/level      		Historical; current review incomplete
      H51-4035A5B60D5B555B09999A0Fdosing.json
      /records/235/clinical_release_verification/release_gate      		Historical; current review incomplete
      H51-F2C85E442635D41891DBA803dosing.json
      /records/235/clinical_release_verification/exact_current_label_candidate      		Historical; current review incomplete
      H51-80783FB5F2409EE59F38E6C8dosing.json
      /records/235/clinical_release_verification/selected_setid      		Historical; current review incomplete
      H51-498DB9D40089997D5A1110FBdosing.json
      /records/235/clinical_release_verification/selected_label_title      		Historical; current review incomplete
      H51-BD22B8DABAE65F259BA04DC1dosing.json
      /records/235/clinical_release_verification/numeric_support_ratio      		Historical; current review incomplete
      H51-2DB38C7A7571BEDA84C9919Fdosing.json
      /records/235/clinical_release_verification/reference_url_count      		Historical; current review incomplete
      H51-A310F1D751EA0B5E0FCB2709dosing.json
      /records/235/clinical_release_verification/broken_reference_count      		Historical; current review incomplete
      H51-2B6E55DFE1C16820B53A2EAAdosing.json
      /records/235/clinical_release_verification/point_of_use_confirmation_required      		Historical; current review incomplete
      H51-39A119F19F88F5FA5E85832Cdosing.json
      /records/235/clinical_release_verification/note      		Historical; current review incomplete
      H51-CBC6D214B77C77B9721395B3dosing.json
      /records/235/clinical_release_verification/dailymed_search_url      		Historical; current review incomplete
      H51-7684F288397EC9C36BDEACEAfirst-look-v5.1.json
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      H51-521FFA1FC641FB2885C313D7preparation-assessments-v3.8.json
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      /235/route_presence/structured_dilution      		Historical; current review incomplete
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      /235/route_presence/continuous_infusion      		Historical; current review incomplete
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      /235/route_presence/pediatric_source      		Historical; current review incomplete
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      /235/clinical_release_note      		Historical; current review incomplete
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