1]
Significant improvements have been made to our very popular
opioid conversion calc. Users will
now be able to modify the dosing factors that are associated with
methadone conversions. We also added additional dosing schemes
including the Friedman/McPherson and Fudin approaches. The Fudin
equation significantly reduces the dramatic fluctuations in the converted
methadone dose that can occur around the breakpoints in the most common
nomograms - e.g. Ayonrinde, Ripamonte, etc.
Mathematical Model For Methadone
Conversion Examined:Link
Fudin Factor graphically
compared to Ripamonte, Ayonrinde, and
Mercadante -
jpeg
2]
Last month we created a new
drug categories
page that should help locate a particular drug table.
3]
Site-wide search capability:
Occasionally, the large search bar at the top of page may not provide
links to recently developed material. Alternatively, users may
find the Google search functionality much more effective:
Google Site Search
Custom Search
October 01, 2012
Basal Metabolic Rate (BMR) Calculators:
Several of these calculators may be particularly useful for dieters. Just about every single MAJOR calorie/ energy equation that has been released over the last 90 years is included below. Each calculator has a customized printout option for easy analysis. Recommendation: Try each calculator - print out the results - then compare!
Equation:
exp [0.613 + (0.425 x BSA) - (0.0075 x
age) + (0.156 x African-American race) + (0.216
x target INR) - (0.257 x amiodarone) + (0.108 x smokes) + 0.0784 x DVT/PE ]
Reference: Gage BF, Eby C, Johnson JA, Deych E, Rieder MJ, et al.
Use of pharmacogenetic and clinical factors to predict the therapeutic
dose of warfarin. Clin Pharmacol Ther. 2008 Sep;84(3):326-31.
Epub 2008 Feb
27.
New vancomycin single level analysis tool that allows the user
to enter the time that has elapsed since the last dose was given. This updated
version is especially useful if the current dosing schedule was not
adhered to (dose was administered early or late).
Link to program. The original program
requested the time that the trough was drawn prior to the next dose.
New epidural concentration/recipe guide.
Also contains a link to a pop-up calculator for non-standard
concentrations of bupivacaine and/or fentanyl.
A reporting function was added to the bottom of the vancomycin
single level analysis tool based on feedback from a clinical
pharmacist. This section allows the user to copy a detailed
note based on the previous entries and then paste it into an
electronic record.
New calculator:
CKD-EPI Creatinine Equation. This program was written over 2 years ago... Sorry for the late posting.
A new benzodiazepine converter
program was just added. Several references were reviewed in
order to make sure the final equivalent dosages had ample support.
Someone had reported that important entries were missing from
the renal dosing list. An old index page was mistakenly
uploaded. Please review the current
list... it contains several new entries.
March 29th, 2012
We released several updates in the last couple of months including:
Expect
significant updates to the current web site layout. Our last major
update of the web site (page layout) was in 2007. Our
home page will be updated first and the rest of the site will use a
similar layout.
Date:
News Item
September 5th, 2011
Several new drugs were added to the renal dosing section.
Check it out....
We have also moved to a new server! The new
server has four times the capacity of our current traffic levels.
The new environment should improve page load times and errors seen with
some of our programs during extremely busy periods.
April 22, 2011
Several updates were just released (See the medical calculator section).
Also in the coming months, significant upgrades to the
Internal Medicine - Reference section
will be completed.
You will notice that all of the individual
Internal medicine disciplines were added to the left column navigation
section on the home page for easy access.
I will also be reviewing the potential for additional disease state
management calculators... Several beta versions are currently in the
development stage.
If you have any ideas for new calculators, let me know....
Several new calculators will be created in the coming months...
If time permits, a few new disease state management tools will also
be released.
Fiber Analysis
Preliminary research has been completed on a new
fiber analysis tool. Look
for this important release hopefully before the
end of the year. Analysis of
specific soluble fibers can impact
recommendations given to patients with elevated
cholesterol levels or as general nutritional
information. More to come.....
Current tools:
The missing link in
disease pathogenesis??
This topic is extremely important to not only
healthcare professionals, but also the general
public. Future articles will be added to
the nutrition section..... in the meantime,
please research the IMPORTANCE of the ratio
of the omega-6/omega-3 essential fatty acids.
"Several sources of information suggest that
human beings evolved on a diet with a ratio of
omega-6 to omega-3 essential fatty acids (EFA)
of approximately one whereas in Western
diets the ratio is 15/1-16.7/1."
"Excessive amounts of omega-6 polyunsaturated
fatty acids (PUFA) and a very high
omega-6/omega-3 ratio, as is found in today's
Western diets, promote the pathogenesis
of many diseases, including cardiovascular
disease, cancer, and inflammatory and autoimmune
diseases, whereas increased levels of
omega-3 PUFA (a low omega-6/omega-3 ratio) exert
suppressive effects. In the secondary
prevention of cardiovascular disease, a ratio of
4/1 was associated with a 70% decrease in total
mortality. A ratio of 2.5/1 reduced rectal cell
proliferation in patients with colorectal cancer,
whereas a ratio of 4/1 with the same amount of
omega-3 PUFA had no effect."
Source:
Simopoulos AP. The importance of the ratio of omega-6/omega-3 essential
fatty acids. Biomed Pharmacother. 2002 Oct;56(8):365-79.
Harris-Benedict Equation:
Estimation of total calories needed. MOST widely used equation for calculating basal metabolic rate and total calories.
