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Warfarin Dosing
Copyright © GlobalRPh Inc., All Rights Reserved.
Overview
Version 2.0 / Future versions of this program will likely contain proprietary algorithms that will support daily dosing. This current version provides general guidelines based on the information selected below. The responses are derived from statements found in the 6th ACCP guidelines. In many cases direct quotes are used from this valuable reference. Recent studies confirmed the importance of initiating warfarin therapy with lower doses (eg 5mg) as opposed to older protocols which advocated higher initial dosages (7.5 - 10mg). The previous
warfarin calculator
was based on a modified version of the Fennerty nomogram.
What is the range of INR's I should target
?
Select an indication for warfarin therapy
Prophylaxis of venous thrombosis (high risk surgery)
Treatment of venous thrombosis (DVT)
Treatment of pulmonary embolism (PE)
Prevention of systemic embolism
Acute myocardial infarction (AMI)
Valvular Heart Disease
Atrial Fibrillation
Mechanical Prosthetic Valves (high risk)
Bileaflet mechanical valve in aortic position
Certain patients with thrombosis and antiphospholipid synd
Prevent recurrent MI
Initial dose above 5 mg
?
No
Yes
Does the patient have Protein C deficiency
:
No
Yes
What should I do if the patient's INR is outside the therapeutic range
?
Select INR range if elevated
INR above therapeutic range but less than 5.0
INR > 5.0 but less than 9. No significant bleeding
INR > 9.0 and no significant bleeding present
INR > 20 and serious bleeding
Life-threatening bleeding
Is the patient undergoing an invasive procedure
?
No
Yes
Warfarin Info by Al Lodwick
Disclaimer
All calculations must be confirmed before use. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.
Read the disclaimer
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