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Urinary Tract Infections

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Urinary Tract Infections - UTI

Urinary tract infections Possible therapeutic alternatives
UTI: uncomplicated cystitis - urethritis Common pathogens
Bactrim DS orally twice daily for 3 days or
Ciprofloxacin 250mg orally twice daily for 3 days or Norfloxacin 400mg orally twice daily for 3 days or Ofloxacin 200mg orally twice daily for 3 days  or Levofloxacin 250mg orally once daily for 3 days.
Augmentin 875mg orally twice daily or 500mg po tid.
Recurrent cystitis(> 3 episodes per year) Common pathogens
Treat infection with one of the regimens above, then start long term maintenance therapy with Bactrim single-strength one tablet once daily.
Complicated UTI: catheter in place, obstruction etc. Common pathogens
[Ampicillin 1 gram IV every 6 hours + Gentamicin IV]  or    
Ciprofloxacin 200-400mg IV every 12 hours or Levofloxacin 250 to 500mg IV qd  or 
Piperacillin-tazobactam 3.375 grams IV every 6 hours   or  
Imipenem 500mg IV  q6h
Gonococcal urethritis Neisseria gonorrhoeae
Cefixime 400 mg PO x 1 PLUS [ Azithromycin 1 g PO x 1 OR Doxycycline 100 mg PO bid x 7 d if chlamydia infection has not been ruled out]
Ceftriaxone 125 mg IM x 1  PLUS  [Azithromycin 1 g PO x 1 OR Doxycycline 100 mg PO bid x 7 d if chlamydia infection has not been ruled out]
non-gonococcal urethritis Chlamydia trachomatis
Azithromycin 1 g PO x 1
Doxycycline 100 mg PO bid x 7d
Recurrent or persistent urethritis Common pathogens
Metronidazole 2 grams po once + Erythromycin base 500 mg PO qid x 7 days
Metronidazole 2 grams PO once + erythromycin ethylsuccinate 800 mg PO qid x 7 days

Images

Acute cystitis
(Bladder infection)
Cross-section

References - Infectious Disease Section

Infectious Disease References

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.
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