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Saquinavir - Invirase ®, Fortovase ® - Renal Dosing

Usual Dosing (Adults)

HIV:
Unboosted regimen: Fortovase®: 1200 mg tid or 1600 mg bid within 2 hours after a meal in combination with a nucleoside analog

Ritonavir-boosted regimens:
Fortovase®: 1000 mg bid in combination with ritonavir 100 mg twice daily.
Invirase®: 1000 mg bid given in combination with ritonavir 100 mg twice daily. This combination should be given together and within 2 hours after a full meal in combination with a nucleoside analog.

Renal Dosing

dialysis No adjustment required

Hemodialysis

dialysis Hemo: insufficient data. However, the need for adjustment is unlikely.

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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