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Ofloxacin

Usual Dosing (Adults)
200-400 mg po or IV q12h.

Renal Dosing
dialysis [> 50 ml/min]: no changes

[20-50]: 200-400mg q24h.

[<20]: 100-200mg q24h (one-half of usual dose q24h.)

Hemodialysis
dialysis Hemodialysis:  Manufacturer states: For CRCL <20 ml/min give 50% of usual dose q24h. No specific info for hemodialysis. 

Continuous arteriovenous or venovenous hemodiafiltration effects: Administer 300 mg every 24 hours

Reference(s)
National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.
Ofloxacin