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Pulmonary - Mast Cell stabilizers
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cromolyn sodium (Intal ®)
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Inhalation: May be used as an adjunct in the prophylaxis of allergic
disorders, including asthma; prevention of exercise-induced bronchospasm
--------------------------- Dosing: Inhalation: For chronic control of asthma, taper frequency to the lowest effective dose (ie, 4 times/day to 3 times/day to twice daily): Nebulization solution: Children >2 years and Adults: Initial: 20 mg 4 times/day; usual dose: 20 mg 3-4 times/day Metered spray: Children 5-12 years: Initial: 2 inhalations 4 times/day; usual dose: 1-2 inhalations 3-4 times/day Children >/= 12 years and Adults: Initial: 2 inhalations 4 times/day; usual dose: 2-4 inhalations 3-4 times/day Prevention of allergen- or exercise-induced bronchospasm: Administer 10-15 minutes prior to exercise or allergen exposure but no longer than 1 hour before: Nebulization solution: Children >2 years and Adults: Single dose of 20 mg Metered spray: Children >5 years and Adults: Single dose of 2 inhalations --------------------------- Supplied: Aerosol, for oral inhalation, as sodium (Intal®): 800 mcg/inhalation (8.1 g) [112 metered inhalations; 56 doses], (14.2 g) [200 metered inhalations; 100 doses] Solution for nebulization, as sodium (Intal®): 20 mg/2 mL (60s, 120s) |
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nedocromil (Tilade ®)
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Use Aerosol: Maintenance therapy in patients with mild to moderate bronchial asthma Mechanism of Action Inhibits the activation of and mediator release from a variety of inflammatory cell types associated with asthma including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets; it inhibits the release of histamine, leukotrienes, and slow-reacting substance of anaphylaxis; it inhibits the development of early and late bronchoconstriction responses to inhaled antigen ------------------------ Dosing: Inhalation: Children >6 years and Adults: 2 inhalations 4 times/day; may reduce dosage to 2-3 times/day once desired clinical response to initial dose is observed -------------------------- Supplied: Aerosol for inhalation, as sodium (Tilade®): 1.75 mg/activation (16.2 g) |
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Disclaimer |
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Listed dosages are for - Adult patients ONLY. PLEASE READ THE
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