Neuromuscular blockade: Initial: 0.06-0.1 mg/kg or 0.05 mg/kg after initial dose
of succinylcholine for intubation; maintenance dose: 0.01 mg/kg 60-100 minutes
after initial dose and then 0.01 mg/kg every 25-60 minutes.
Neuromuscular blockade in the ICU: 0.05-0.1 mg/kg bolus followed by 0.8-1.7
mcg/kg/minute once initial recovery from bolus observed or 0.1-0.2 mg/kg every
Elimination half-life is doubled, plasma clearance is reduced, and
rate of recovery is sometimes much slower.
[CRCL 10-50 ml/min]: Administer 50% of normal dose.
[<10 ml/min]: Do not use.
Do not use.
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