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Ofloxacin - Floxin ® - Renal Dosing

Usual Dosing (Adults)

200-400 mg po or IV q12h.

Renal Dosing

dialysis [> 50 ml/min]: no changes

[20-50]: 200-400mg q24h.

[<20]: 100-200mg q24h (one-half of usual dose q24h.)

Hemodialysis

dialysis Hemodialysis:  Manufacturer states: For CRCL <20 ml/min give 50% of usual dose q24h. No specific info for hemodialysis. 

Continuous arteriovenous or venovenous hemodiafiltration effects: Administer 300 mg every 24 hours

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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