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Opioids - Equianalgesic Dosages
Drug
Duration
Half-life
Route
Equianalgesic
Dosage
Codeine
4–6 h
3 h
IM
120 mg
PO
200 mg
Fentanyl
1–2 h
1.5–6 h
IM
0.1 mg
Hydrocodone
4–8 h
3.3–4.5 h
PO
30 mg
Hydromorphone
4–5 h
2–3 h
IM
1.3–1.5 mg
PO
7.5 mg
Levorphanol
6–8 h
12–16 h
IM
2 mg
PO
4 mg
Meperidine
2–4 h
3–4 h
IM
75 mg
PO
300 mg
Methadone
4–6 h
15–30 h
IM
10 mg
PO
10–20 mg
Morphine
3–7 h
1.5–2 h
IM
10 mg
PO
30
–60 mg
Oxycodone
4–6 h
NA
PO
15-30 mg (20 mg)
Oxymorphone
3–6 h
NA
IM
1 mg
PR
10 mg
Propoxyphene
4–6 h
6–12 h
PO
130-200 mg *
(Inconclusive data)
*Propoxyphene HCL: 130mg; Napsylate: 200mg. Not recommended for chronic pain.
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