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Magnesium Supplements

Usual Dosing (Adults)

See the magnesium supplement guide....

Renal Dosing

dialysis Overview: Renal Insufficiency:
Magnesium is excreted solely by the kidney.
In patients with severe renal insufficiency (e.g. < 30 ml/min), the dose should be lower and frequent serum magnesium levels must be obtained


Caution should be used when replacing magnesium in any patient with renal insufficiency.

Magnesium balance is primarily a kidney function (magnesium intake does not appear to be regulated). The average diet provides 20 - 30 mEq daily, but the net absorption is only about 7 mEq. The kidneys normally excrete an equal amount in order to maintain the magnesium balance. However, in the presence of magnesium deficiency urinary magnesium excretion can be reduced to a minimum of about 2 mEq/day. Renal magnesium  reabsorption takes place primarily in the proximal tubule (30% of the filtered load) and the thick ascending limb of Henle's loop (65%). Overall renal reabsorption appears to be saturable, so that a higher magnesium intake results in a proportional increase in urinary excretion. For this reason, it is difficult for patients with normal renal function to develop hypermagnesemia.

Hemodialysis

dialysis See comments above.

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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