Magnesium Supplements

Usual Dosing (Adults)

See the magnesium supplement guide....

Renal Dosing

dialysis Overview: Renal Insufficiency:
Magnesium is excreted solely by the kidney.
In patients with severe renal insufficiency (e.g. < 30 ml/min), the dose should be lower and frequent serum magnesium levels must be obtained

Caution should be used when replacing magnesium in any patient with renal insufficiency.

Magnesium balance is primarily a kidney function (magnesium intake does not appear to be regulated). The average diet provides 20 - 30 mEq daily, but the net absorption is only about 7 mEq. The kidneys normally excrete an equal amount in order to maintain the magnesium balance. However, in the presence of magnesium deficiency urinary magnesium excretion can be reduced to a minimum of about 2 mEq/day. Renal magnesium  reabsorption takes place primarily in the proximal tubule (30% of the filtered load) and the thick ascending limb of Henle's loop (65%). Overall renal reabsorption appears to be saturable, so that a higher magnesium intake results in a proportional increase in urinary excretion. For this reason, it is difficult for patients with normal renal function to develop hypermagnesemia.


dialysis See comments above.


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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