Magnesium Dosing

Use this calculator to estimate the expected serum sodium level increase after specifying the infusion rate and length of infusion of a 0.9 NS solution.
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(1)  Flink EB. Magnesium deficiency. Etiology and clinical spectrum.  Acta Med Scand Suppl 1981;647:125-37

"The documentation of normal renal function is absolutely necessary for maximum doses. The order of magnitude of dose is 1.0 meq Mg/kg on day 1, and 0.3 to 0.5 mEq/kg per day for 3 to 5 days. In emergencies such as convulsions or ventricular arrhythmias, a bolus injection of 1.0 gm (8.1 meq) of MgSO4 is indicated. Therapy of Mg deficiency in the presence of renal insufficiency requires smaller doses and frequent monitoring. Complete repletion occurs slowly."
(2) Abbott LG, Rude RK. Department of Endocrinology, LAC+USC Medical Center, Los Angeles 90033. Clinical manifestations of magnesium deficiency. Miner Electrolyte Metab 1993;19(4-5):314-22.

(3) Berkelhammer C, Bear RA. A clinical approach to common electrolyte problems: 4. Hypomagnesemia. Can Med Assoc J 1985 Feb 15;132(4):360-8. 

(4) DiPalma JR. Magnesium replacement therapy. Am Fam Physician 1990 Jul;42(1):173-6

(5) al-Ghamdi SM, Cameron EC, Sutton RA. Magnesium deficiency: pathophysiologic and clinical overview. Am J Kidney Dis. 1995 Jun;25(6):973. // 
Am J Kidney Dis 1994 Nov;24(5):737-52. 

(6) Tso EL, Barish RA. Magnesium: clinical considerations. J Emerg Med 1992 Nov-Dec; 10(6):735-45. 

(7) Kingston ME, Al-Siba'i MB, Skooge WC. Clinical manifestations of hypomagnesemia. 
Crit Care Med 1986 Nov;14(11):950-4 . 

(8) Whang R, Hampton EM, Whang DD. Magnesium homeostasis and clinical disorders of magnesium deficiency. Ann Pharmacother 1994 Feb;28(2):220-6.


All calculations must be confirmed before use. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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