Hypertonic
saline is usually reserved for severe hyponatremia (sodium < 115 meq/L).
This calculator targets a level of 120 or 125 meq/L and determines the
rate necessary to increase the serum sodium at 0.5 meq/L/hr. Look here
for a review of hyponatremia. In severe cases, the maximum sodium
increase within the first 24 hours should not exceed 10 to 12 meq/liter
in order to reduce the risk of CNS lesions and/or pulmonary edema. |
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