logo

Laboratory Values

Unless noted, all values are for adults

  Updated Laboratory Section can  be found here: 
new icon
  labs_home.htm
Arterial blood gases - review;    Anion gap (review);    ANC calculator.
Albumin 3.2 - 5 g/dl
Alkaline phosphatase
(Adults: 25-60)
33 - 131 IU/L
                Adults > 61 yo: 51 - 153 IU/L
Ammonia 20 - 70 mcg/dl
Bilirubin, direct 0 - 0.3 mg/dl
Bilirubin, total 0.1 - 1.2 mg/dl

Blood Gases

  Arterial Venous
pH 7.35 - 7.45 7.32 - 7.42
pCO2 35 - 45 38 - 52
pO2 70 - 100 28 - 48
HCO3 19 - 25 19 - 25
O2 Sat % 90 - 95 40 - 70
BUN 7 - 20 mg/dl

Complete blood count (CBC)  Adults

  Male Female
Hemoglobin (g/dl) 13.5 - 16.5 12.0 - 15.0
Hematocrit (%) 41 - 50 36 - 44
RBC's ( x 106 /ml) 4.5 - 5.5 4.0 - 4.9
RDW (RBC distribution width) < 14.5
MCV 80 - 100
MCH 26 - 34
MCHC % 31 - 37
Platelet count 100,000 to 450,000

Creatine kinase (CK) isoenzymes

CK-BB 0%
CK-MB (cardiac) 0 - 3.9%
CK-MM 96 - 100%
Creatine phosphokinase (CPK) 8 - 150 IU/L
Creatinine (mg/dl) 0.5 - 1.4

Electrolytes

Calcium 8.8 - 10.3 mg/dL
Calcium, ionized 2.24 - 2.46 meq/L
Chloride 95 - 107 mEq/L
Magnesium 1.6 - 2.4 mEq/L
Phosphate 2.5 - 4.5 mg/dL
Potassium 3.5 - 5.2 mEq/L
Sodium 135 - 147 mEq/L

Other

Ferritin  (ng/ml) 13 - 300
Folate  (ng/dl) 3.6 - 20
Glucose, fasting  (mg/dl) 60 - 110
Glucose (2 hours postprandial)  (mg/dl) Up to 140
Hemoglobin A1c <6% of total Hb
AACE Guidelines (2011)
Hemoglobin A1c, % (as a screening test)
leq5.4 - Normal
-------------------------
5.5-6.4 - High risk/prediabetes; requires screening by glucose criteria
-------------------------
geq6.5 -Diabetes, confirmed by repeating the test on a different day
=================
In general, therapy should target a A1C level of 6.5% or less for most nonpregnant adults.
Iron  (mcg/dl) 65 - 150
Lactic acid  (meq/L) 0.7 - 2.1
LDH (lactic dehydrogenase)  56 - 194 IU/L

Lipoproteins and triglycerides

Cholesterol, total < 200 mg/dl
HDL cholesterol geq 35 mg/dL.  Negative risk factor:  geq 60 mg/dL
LDL cholesterol 65 - 180 mg/dl
Triglycerides Normal: < 150 mg/dL.
Borderline-high: 150 to 199 mg/dL
High: 200 to 499 mg/dL
Very High: >499 mg/dL
   
Osmolality 289 - 308 mOsm/kg
SGOT (AST) < 35 IU/L  (20-48)
SGPT (ALT) <35 IU/L
Testosterone - total (serum) Male: 300 to 1000 ng/dL
Female: < 62 ng/dL

ALT:
Male:
14-15 yr: 33-585 ng/dL
16-17 yr: 185-886 ng/dL
18-39 yr: 400-1080 ng/dL
40-59 yr: 350-890 ng/dL
> 60 yr: 350-720 ng/dL

Tanner Stage IV: 165-854 ng/dL
Tanner Stage V: 194-783 ng/dL

Thyroid Function tests

Thyroid Function Testing
Thyroid Function Test
Measurement
Normal Range
Total T4 (TT4) bound and free T4 4.5 -11.5 ug/dL
Free T4 (FT4) free T4 0.8 -2.8 ng/dL
Free T4 Index (FT4I) estimate of free T4
FT4I = TT4 x RT3U
1.0 -4.3 U
Total T3 (TT3) bound and free T3 75 -200 ng/dL
Resin T3 Uptake (RT3U) binding capacity of TBG 25 -35%
TRH TRH 5 -25 mIu/mL
TSH TSH 0.5 - 4.70 µIU/mL

American Association of Clinical Endocrinologists guidelines changed their normal range for TSH to
0.3 - 3.04 mIU/L.
Thyroglobulin Thyroglobulin 5-25 ng/mL
Radioactive Iodine Uptake (RAIU) Distribution of radiolabeled iodine in the thyroid 5 hr – 5 to 15%
24 hr – 15 to 35%
Notes:
Free T4
- much more useful then total T4 (e.g. interested in unbound or active form).  Total T4 not commonly measured. Greatly affected by TBG. 
Free T4 index
: indirect measure of free T4. Corrects for high/low values of TBG.
Total T3
: not as useful as free T3, however, may be useful in locating problems with TBG, or if looking for problems with peripheral conversion of T4 to T3. 
Resin T3 Uptake
: if low, then TBG binding capacity is high. Opposite if high.
TSH
: best measure to determine thyroid function. 
Thyroglobulin
: nonspecific test that is elevated when the thyroid gland is inflamed or enlarged. 
Free T3 2.3-4.2 pg/ml
Total iron binding capacity (TIBC) 250 - 420  mcg/dl
Transferrin > 200 mg/dl
Uric acid    (male) 2.0 - 8.0 mg/dl
                 (female) 2.0 - 7.5 mg/dl

WBC + differential

WBC (cells/ml) 4,500 - 10,000
Segmented neutrophils 54 - 62%
Band forms 3 - 5%  (above 8% indicates left shift)
Basophils 0 - 1   (0 - 0.75%)
Eosinophils 0 - 3   (1 - 3%)
lymphocytes 24 - 44  (25 - 33%)
Monocytes 3 - 6   (3 - 7%)

Absolute Neutrophil Count  (ANC) - Oncology

Equations: 
(1) Segs and bands reported as a percentage: 
WBC * ((segs / 100) + (bands / 100))

 (2) Segs and bands reported in total numbers:
WBC * (segs + bands)

Neutrophils (aka polymorphonuclear cells, PMNs, granulocytes, segmented neutrophils,  or segs) fight against infection and represent a subset of the white blood count. Neutropenia by definition is an ANC below 1800/mm3 (some sources use a lower value).  

Absolute neutrophil count (ANC) of 1000-1800:
Most patients will be given chemotherapy in this range.
Risk of infection is considered low.

Mild neutropenia - Absolute neutrophil count (ANC) of 500-1000
Carries with it a moderate risk of infection.

Absolute neutrophil count (ANC) of less than 500:
Severe
neutropenia - high risk of infection. Remember that a reduced WBC is known as leukopenia.

The WBC consists of the following (differential):
Lymphocytes: 20-40%
Neutrophils: 50-60%
Basophils: 0.5-2%
Eosinophils: 1-4%
Monocytes: 2-9% (average: 4%).
ANC = Total WBC x (% "Segs" + % "Bands") 
Equivalent to: WBC x ((Segs/100) + (Bands/100))

The ANC refers to the total number of neutrophil granulocytes present in the blood. 

Normal value: geq 1500 cells/mm3.
Mild neutropenia: geq1000 - <1500/mm3.
Moderate neutropenia: geq500 - <1000/mm3.
Severe neutropenia: < 500/mm3.

Reference
Ayalew Tefferi, MD, ed. Primary Hematology. Totowa, NJ: Humana Press, 2001
 Updated Laboratory Section
can  be found here
: 
new icon
  labs_home.htm
more Career Center image description
Medical Calculators - A thru Z
Lab Values - A thru Z