Usual
dose: (Medication must be given on an empty stomach. In order to
provide adequate buffering, patients must take at least 2 of the
appropriate strength tablets at each dose when using either the once
daily or twice daily regimens. Patient weight <60 kg:
(Tablets): 125 mg orally twice daily or 250mg once daily or 167 mg
(Buffered powder) twice daily. Patient weight > 60kg:
(Tablets): 200mg orally twice daily or 400mg orally once daily.
(Buffered Powder): 250mg orally twice daily. Supplied:
chewable tablet: (25, 50, 100, 150, and 200mg); Oral powder for
solution (100, 167, and 200mg packets). Renal Dosing:
Usual
dose: 150 mg orally twice daily. Supplied:
[150mg tablet; 10 mg/ml oral solution]. Lamivudine should not
be co-administered with zalcitabine. Renal dosing: crcl >50/
no change; 30-49/ 150mg once daily; 15-29/ 150mg x1,
then 100mg once daily; 5-14/ 150mg x 1, then 50 mg once
daily; <5/ 50mg x1, then 25mg once daily.
Dosing:
Patient weight >60 kg: 40mg orally twice daily . Patient
weight < 60kg: 30mg orally twice daily. Dosages may be decreased
by 50% if peripheral neuropathy occurs. May be taken without
regard to meals. Must decrease dose in renal
dysfunction. Stavudine and Zidovudine should not be
co-administered. Supplied:
[15, 20, 30, 40mg capsules; 1 mg/ml oral powder for solution]
Renal dosing:
Usual
dose: 0.75 mg orally three times daily. Lamivudine should not
be co-administered with zalcitabine. Renal dosing:
>40/ no change; 10-40/ 0.75 mg twice daily;
<10/ 0.75 mg once daily. Supplied:
[0.375mg , 0.75mg tablet]
Usual
dose: 300mg orally twice daily or 200mg orally three times daily or
100mg every 4 hours 5 times daily. Stavudine and Zidovudine
should not be co-administered. Supplied:
100mg capsule; 300mg tablet; 50mg/5ml oral solution. Dosing
in renal failure (<10 ml/min): 100mg every 6 to 8 hours.
Usual
dose: Initially, 200mg orally once daily for 14 days, then
increase to 200mg orally twice daily (may reduce risk of rash). Supplied:
[200mg tablet; 50mg/5 ml oral suspension]
Usual
dose: 800mg orally every 8 hours or 1200mg orally twice
daily (must be taken on an empty stomach). If
administered with Rifabutin: give 1000mg orally every 8
hours. Supplied: [200,
333, and 400mg capsules]
Usual
dose: To reduce the risk of nausea give 300mg orally twice a day for 1
day, then give 400mg orally twice a day for 2 days, then 500mg orally
twice a day for 1 day, then finally 600mg twice daily thereafter.
(Take with food). Supplied: [100mg capsule; 80mg/ml -240ml
oral solution]
Dosing
(Invirase): 600mg orally three times daily with food. Fortovase
(soft gel capsule) 1200mg orally three times daily with food. Supplied:
[200mg capsule]
