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Cardiovascular Medications Useful for Treatment of Various Stages of Heart Failure (HF)
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Cardiovascular Medications Useful for Treatment of Various Stages of Heart Failure (HF)
Drug  Stage A  Stage B Stage C
Ace Inhibitors
Benazepril HTN -- --
Captopril  HTN, Diabetic Nephropathy Post MI* HF*
Enalapril  HTN, Diabetic Nephropathy Asymptomatic left ventricular systolic dysfunction HF 
Fosinopril  HTN   HF 
Lisinopril  HTN, Diabetic Nephropathy  Post MI HF 
Moexipril  HTN --- --
Perindopril  HTN, CV Risk --- --
Quinapril  HTN --- HF
Ramipril  HTN, CV Risk Post MI Post MI
Trandolapril  HTN Post MI Post MI
Angiotensin Receptor Blockers
Candesartan  HTN -- HF 
Eprosartan  HTN -- --
Irbesartan  HTN, Diabetic Nephropathy -- --
Losartan  HTN, Diabetic Nephropathy CV Risk* --
Olmesartan  HTN -- --
Telmisartan  HTN -- --
Valsartan  HTN, Diabetic Nephropathy Post MI Post MI, HF
Aldosterone Blockers 
Eplerenone  HTN Post MI Post MI
Spironolactone  HTN -- HF 
Beta Blockers
Acebutolol  HTN -- -- 
Atenolol  HTN Post MI --
Betaxolol  HTN -- -- 
Bisoprolol  HTN -- HF
Carteolol  HTN -- -- 
Carvedilol  HTN Post MI Post MI, HF
Labetalol  HTN -- -- 
Metoprolol succinate HTN -- HF
Metoprolol tartrate  HTN Post MI --
Nadolol  HTN -- -- 
Penbutolol  HTN -- -- 
Pindolol  HTN -- -- 
Propranolol  HTN Post MI -- 
Timolol  HTN Post MI -- 
Other
Digoxin  -- -- HF
CV Risk: reduction in future cardiovascular events.  HF: heart failure. Post MI: reduction in heart failure or other cardiac events following MI.



Medications Commonly Used for the Treatment of Patients with Heart Failure with Low Ejection Fraction
Drug Initial Daily Dose(s) Maximum Dose(s)
ACE-Inhibitors
Captopril 6.25 mg tid 50mg tid
Enalapril 2.5 mg bid 10 to 20 mg bid
Fosinopril 5 to 10mg qd 40mg qd
Lisinopril 2.5 to 5 mg qd 20 to 40 mg qd
Perindopril 2 mg qd 8 to 16 mg qd
Quinapril 5 mg bid 20 mg bid
Ramipril 1.25 to 2.5 mg qd 10mg qd
Trandolapril 1 mg qd 4 mg qd
Angiotensin Receptor Blockers
Candesartan 4 to 8 mg qd 32 mg qd
Losartan 25 to 50 mg qd 50 to 100 mg qd
Valsartan 20 to 40 mg bid 160 mg bid
Aldosterone Antagonists
Spironolactone 12.5 to 25 mg qd 25 mg qd to bid
Eplerenone 25 mg qd 50 mg qd
Beta-Blockers
Bisprolol 1.25 mg qd 10 mg qd
Carvedilol 3.125 mg bid 25 mg bid. 50mg bid for patients > 85 kg.
Metoprolol succinate extended release 12.5 to 25 mg qd 200mg qd

Reference

Direct quotes from this valuable reference:
Hunt SA, Abraham WT, Chin MH, Feldman AM, et al. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation. 2005 Sep 20;112(12):e154-235. Epub 2005.  
Link: http://circ.ahajournals.org/cgi/content/full/112/12/e154

Disclaimer

All calculations must be confirmed before use. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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