fesoterodine fumarate - Toviaz ®

Usual Dosing (Adults)

Toviaz is a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. (1)

DOSAGE AND ADMINISTRATION-------------------------------------
The recommended starting dose of Toviaz is 4 mg once daily. Based upon individual response and tolerability, the dose may be increased to 8 mg once daily. (2)

The daily dose of Toviaz should not exceed 4 mg in the following populations:

 -Patients with severe renal impairment (CLCR <30 mL/min)
 -Patients taking potent CYP3A4 inhibitors, such as ketoconazole, itraconazole, and clarithromycin.

Toviaz is not recommended for use in patients with severe hepatic impairment (Child-Pugh C).

Toviaz should be taken with liquid and swallowed whole. Toviaz can be administered with or without food, and should not be chewed, divided, or crushed.

Toviaz 4 mg extended-release tablets are light blue, oval, biconvex, film-coated, and engraved with "FS" on one side.

Toviaz 8 mg extended-release tablets are blue, oval, biconvex, film-coated, and engraved with "FT" on one side.

Renal Dosing

dialysis The daily dose of Toviaz should not exceed 4 mg in patients with severe renal impairment (CLCR <30 mL/min).


dialysis See above.


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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