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BROWSE topics
Epidural Preparations
Common agents: bupivacaine, fentanyl, ropivacaine |
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Determine volume of epidural additives:
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| Volumes listed below
assume a final volume of 250 ml. If a volume
other than 250ml is requested and any of the following
additives are required (bupivacaine, fentanyl - alone or in
combination), use our
Popup calculator Using this chart: Example order: Epidural: 0.125% bupivacaine with fentanyl concentration of 2 mcg/ml. ---------------------------------------------- Using the table below, this would require 62.5 ml of bupivacaine and 10 ml of fentanyl for a total volume of 62.5 + 10 = 72.5ml. Remove 72.5 ml from a 250 ml bag and then add the additives listed above for a total volume of 250 ml. |
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| Bupivacaine 0.5% vials (preservative-free): | |
| Desired concentration | Volume needed |
| 0.0625% | 31.25 ml |
| 0.075% | 37.5 ml |
| 0.1% | 50 ml |
| 0.125 % | 62.5 ml |
| Bupivacaine 0.25% vials (preservative-free): | |
| Desired concentration | Volume needed |
| 0.0625% | 62.5 ml |
| 0.075% | 75 ml |
| 0.1% | 100 ml |
| 0.125 % | 125 ml |
| Ropivacaine 0.5% vials (preservative-free): | |
| Desired concentration | Volume needed |
| 0.2% (preferred) | 100ml |
| Ropivacaine 1.0% ampule (preservative-free): | |
| Desired concentration | Volume needed |
| 0.2% (preferred) | 50 ml |
| Fentanyl 50 mcg/ml (preservative-free): | |
| Desired concentration | Volume needed |
| 2 mcg/ml | 10 ml |
| 5 mcg/ml | 25 ml |
| 7.5 mcg/ml | 37.5 ml |
| 10 mcg/ml | 50 ml |
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Hydromorphone 10 mg/ml (preservative-free): Look carefully at vial - many contain sodium metabisulfite which cannot be used. |
|
| Desired concentration | Volume needed |
| 25 mcg/ml | 0.625 ml |
| 50 mcg/ml | 1.25 ml |
| 75 mcg/ml | 1.875 ml |
Disclaimer
David F. McAuley, Pharm.D., R.Ph. GlobalRPh Inc.
