DVT prophylaxis (hip / knee surgery): 30 mg SC every 12 hours starting 12-24
hours postop. Alternative for hip: 40 mg SC once daily starting 12 hours preop.
DVT treatment (Outpatient): 1 mg/kg SC every 12 hours until oral anticoagulation
DVT treatment (Inpatient): 1 mg/kg SC every 12 hours or 1.5 mg/kg SC once
Unstable angina or non-Q-wave MI: 1 mg/kg SC every 12 hours
Prophylaxis in acute medically ill patients (high risk): 40 mg SC qd x 6-11 days
(up to 14 days).
[CRCL >30 ml/min]: No specific adjustment
recommended (per manufacturer).
[CRCL < 30 ml/min]:
DVT prophylaxis in abdominal surgery, hip replacement, knee replacement,
or in medical patients during acute illness:
30mg SC qd.
DVT treatment (inpatient or outpt treatment in conjunction with warfarin):
1 mg/kg SC q24h.
Unstable angina, non-Q-wave MI (with ASA): 1 mg/kg SC q24h.
Enoxaparin has not been FDA approved for use in dialysis patients.
It's elimination is primarily via the renal route. Serious bleeding
complications have been reported with use in patients who are dialysis
dependent or have severe renal failure.
National Institutes of Health, U.S. National Library of Medicine,
DailyMed Database. Provides access to the latest drug monographs submitted to the
Food and Drug Administration (FDA). Please review the latest applicable package insert for
additional information and possible updates. A local search
option of this data can be found here.
The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical
judgment. Neither GlobalRPh Inc. nor any other party involved in the
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