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Emtricitabine - Emtriva © - Renal dosing

Usual Dosing (Adults)

Recommended Dose
EMTRIVA may be taken without regard to food.

Adult Patients (18 years of age and older)
EMTRIVA capsules: one 200 mg capsule administered once daily orally.
EMTRIVA oral solution: 240 mg (24 mL) administered once daily orally.

Pediatric Patients (0–3 months of age)
EMTRIVA oral solution: 3 mg/kg administered once daily orally.

Pediatric Patients (3 months through 17 years)
EMTRIVA oral solution: 6 mg/kg up to a maximum of 240 mg (24 mL) administered once daily orally.
EMTRIVA capsules: for children weighing more than 33 kg who can swallow an intact capsule, one 200 mg capsule administered once daily orally.


Renal Dosing

dialysis Dose Adjustment in Adult Patients with Renal Impairment
  Creatinine Clearance (mL/min)
Formulation >/=50 mL/min 30–49 mL/min 15–29 mL/min <15 mL/min
or on hemodialysis*
*Hemodialysis Patients: If dosing on day of dialysis, give dose after dialysis
Capsule
(200 mg)
200 mg every
24 hours
200 mg every
48 hours
200 mg every
72 hours
200 mg
every
96 hours
Oral Solution
(10 mg/mL)
240 mg every
24 hours
(24 mL)
120 mg every
24 hours
(12 mL)
80 mg every
24 hours
(8 mL)
60 mg every
24 hours
(6 mL)

Although there are insufficient data to recommend a specific dose adjustment of EMTRIVA in pediatric patients with renal impairment, a reduction in the dose and/or an increase in the dosing interval similar to adjustments for adults should be considered.

Hemodialysis

dialysis See above

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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