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VRAYLAR ™ - cariprazine capsule

Please see package insert for additional information and possible updates. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.    [  Read the disclaimer    |   <<Back      |  Other antipsychotics led       ]
CLINICAL PHARMACOLOGY INDICATIONS AND USAGE
DOSAGE AND ADMINISTRATION HOW SUPPLIED

CLINICAL PHARMACOLOGY: top of page

Initial U.S. Approval:  2015

Mechanism of Action: The mechanism of action of cariprazine in schizophrenia and bipolar I disorder is unknown. However, the efficacy of cariprazine could be mediated through a combination of partial agonist activity at central dopamine D2 and serotonin 5-HT1A receptors and antagonist activity at serotonin 5-HT2A receptors. Cariprazine forms two major metabolites, desmethyl cariprazine (DCAR) and didesmethyl cariprazine (DDCAR), that have in vitro receptor binding profiles similar to the parent drug.

INDICATIONS AND USAGE  top of page


INDICATIONS AND USAGE: VRAYLAR™ is indicated for the:
Treatment of schizophrenia.
Acute treatment of manic or mixed episodes associated with bipolar I disorder.

DOSAGE AND ADMINISTRATION  top of page

Drug UPDATES:  VRAYLAR ™ - cariprazine capsule
[Drug information  /  PDF]    Click link for the latest monograph
Dosing:  Click (+) next to Dosage and Administration section (drug info link)

HOW SUPPLIED top of page


HOW SUPPLIED:
 VRAYLAR (cariprazine) capsules are available in four strengths.

1.5 mg capsules: White cap and body imprinted with "FL 1.5"
3 mg capsules: Green to blue-green cap and white body imprinted with "FL 3"
4.5 mg capsules: Green to blue-green cap and body imprinted with "FL 4.5"
6 mg capsules: Purple cap and white body imprinted with "FL 6"

REFERENCE


[Drug information  /  PDF]    Click link for the latest monograph
Medical Calculators - A thru Z
Lab Values - A thru Z