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Doripenem - DORIBAX™ - renal dosing

Usual Dosing (Adults)

DOSAGE AND ADMINISTRATION:
500 mg every 8 hours by intravenous infusion administered over one hour for
patients greater than or equal18 years of age.

Renal Dosing

dialysis Renal Dosing:
CrCl (mL/min)  Recommended Dose
>50 No dosage adjustment necessary
greater than or equal 30 to less than or equal 50  250 mg IV (over 1 hour) every 8 hours
>10 to < 30 250 mg IV (over 1 hour) every 12 hours

Hemodialysis

dialysis DORIBAX™ is hemodialyzable; however, there is insufficient information to make dose adjustment recommendations in patients on hemodialysis

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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