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Delavirdine - Rescriptor ® - Renal Dosing

Usual Dosing (Adults)

The recommended dosage for RESCRIPTOR Tablets is 400 mg (four 100 mg or two 200 mg tablets) three times daily. RESCRIPTOR should be used in combination with other antiretroviral therapy. The complete prescribing information for other antiretroviral agents should be consulted for information on dosage and administration.

The 100 mg RESCRIPTOR Tablets may be dispersed in water prior to consumption. To prepare a dispersion, add four 100 mg RESCRIPTOR Tablets to at least 3 ounces of water, allow to stand for a few minutes, and then stir until a uniform dispersion occurs. The dispersion should be consumed promptly. The glass should be rinsed with water and the rinse swallowed to insure the entire dose is consumed. The 200 mg tablets should be taken as intact tablets, because they are not readily dispersed in water. Note: The 200 mg tablets are approximately one-third smaller in size than the 100 mg tablets.

RESCRIPTOR Tablets may be administered with or without food. Patients with achlorhydria should take RESCRIPTOR with an acidic beverage (e.g., orange or cranberry juice). However, the effect of an acidic beverage on the absorption of delavirdine in patients with achlorhydria has not been investigated.

Patients taking both RESCRIPTOR and antacids should be advised to take them at least one hour apart.

Renal Dosing

dialysis No adjustment required.

Hemodialysis

dialysis Insufficient data

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.   Read the disclaimer
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