Cidofovir - Vistide ® - Renal Dosing

Usual Dosing (Adults)

Treatment of cytomegalovirus (CMV) retinitis: (Patient must meet the following criteria first: serum creatinine </= 1.5, CRCL >55ml/min and urine protein < 100 mg/dL).

Induction: 5 mg/kg qweek x 2.
Maintenance: 5 mg/kg q2weeks.

Note: Probenecid must be administered orally with each dose of cidofovir.

Renal Dosing

Cidofovir is contraindicated in patients with a serum creatinine concentration > 1.5 mg/dL, a calculated creatinine clearance </= 55 mL/min, or a urine protein >/= 100 mg/dL (equivalent to >/= 2 + proteinuria).

Hemodialysis

Contraindicated.

Disclaimer

All calculations must be confirmed before use. The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. Read the disclaimer

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