The adult dosage ranges from 1 to 4 g daily in divided doses. The usual adult
dose is 250 mg every 6 hours. For the following infections, a dosage of 500 mg
may be administered every 12 hours: streptococcal pharyngitis, skin and skin
structure infections, and uncomplicated cystitis in patients over 15 years of
age. Cystitis therapy should be continued for 7 to 14 days. For more severe
infections or those caused by less susceptible organisms, larger doses may be
needed. If daily doses of Cephalexin Capsules, USP greater than 4 g are
required, parenteral cephalosporins, in appropriate doses, should be considered.
Cephalexin Oral Suspension may be better suited for certain dosages in the
The usual recommended daily dosage for pediatric patients is 25 to 50 mg/kg in
divided doses. For streptococcal pharyngitis in patients over 1 year of age and
for skin and skin structure infections, the total daily dose may be divided and
administered every 12 hours.
In severe infections, the dosage may be doubled.
In the therapy of otitis media, clinical studies have shown that a dosage of 75
to 100 mg/kg/day in 4 divided doses is required.
In the treatment of -hemolytic
streptococcal infections, a therapeutic dosage of Cephalexin Capsules, USP
should be administered for at least 10 days.
[CRCL >30 ]: no changes.
[10-30 ]: 250-500 mg q8-12h.
[<10 ml/min]: 250-500mg q12-24h.
250-500mg q12-24h (Dose should be given after dialysis on dialysis
National Institutes of Health, U.S. National Library of Medicine,
DailyMed Database. Provides access to the latest drug monographs submitted to the
Food and Drug Administration (FDA). Please review the latest applicable package insert for
additional information and possible updates. A local search
option of this data can be found here.
The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical
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