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Pharyngitis  Possible therapeutic alternatives
Pharyngitis: "Strept throat" (Usual duration of treatment: 10 days.  5 days for Zithromax) Common pathogens
PenVk 250-500mg every 6 hours  or  
Benzathine penicillin 1.2 mu IM x 1.
Erythomycin 500mg four times daily  or    
Ceftin 250mg orally twice daily  or 
Vantin 100 mg orally twice daily  or
Cefzil 500mg orally once daily  or
Clarithromycin 250mg to 500 mg twice daily or
Zithromax 500mg x 1, then 250mg orally once daily x 4 days.
Pharyngitis: Gonococcal Neisseria gonorrhoeae
Ceftriaxone 125mg IM + doxycycline 100mg orally twice daily for 7 days
Ciprofloxacin 500mg orally  x 1, then  doxycycline 100mg orally twice daily for 7 days
Azithromycin (Zithromax) 2 grams orally x 1.

Sore throat:
Cepacol (benzocaine 10mg + menthol 2mg):  Dissolve one lozenge in mouth every 2-4hours as needed.
Chloraseptic throat spray (phenol 1.4 %):  Spray 5 times onto throat, gums or canker sore every 2-4 hours as needed.

 

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Antimicrobial Series
References

American Hospital Formulary Service.  Drug Information. Bethesda, MD: ASHP, 1997.
Baden LR, Eisenstein BI.Impact of Antibiotic Resistance on the Treatment of Gram-negative Sepsis.
Curr Infect Dis Rep. 2000 Oct;2(5):409-416.
Bartlett JG et al. Community-acquired pneumonia in adults: guidelines for management. Guidelines from the Infectious Diseases Society of America. Clin Infect Dis. 1998;26:811-38.
Bartlett JG: Empirical therapy of community-acquired pneumonia: macrolides are not ideal choices. Semin Respir Infect 1997 Dec; 12(4): 329-33
Bartlett JG.1998 Pocket Book of Infectious Disease Therapy., Ninth Edition. Baltimore,MD: Williams&Wikins,1998.
Bernstein JM: Treatment of community-acquired pneumonia--IDSA guidelines. Infectious Diseases Society of America. Chest 1999 Mar; 115(3 Suppl): 9S-13S
Drug Information Handbook, 5th Ed. 1997, Lexi-Comp inc. 
Ewig S et al. Pneumonia acquired in the community through drug-resistant Streptococcus pneumoniae. Am J Respir Crit Care Med. 1999;159:1835-42.
File TM Jr. Community-acquired pneumonia: recent guidelines for therapy. J Respir Dis. 1999;20:534-41.
Gilbert DN, Moellering RC, Sande MA. The Sanford Guide to Antimicrobial Therapy 2000. 30th ed. Hyde Park,VT: Antimicrobial Therapy, Inc.; 2000.
Gold HS, Moellering RC. Antimicrobial-drug resistance. N Engl J Med. 1996;335:1445-1453.
Gonzales R, Sande M: What will it take to stop physicians from prescribing antibiotics in acute bronchitis? Lancet 1995 Mar 18; 345(8951): 665-6
Hooton TM, Stamm WE. Diagnosis and treatment of uncomplicated urinary tract infection. Infect Dis Clin North Am 1997;11:551-581.
Lipsky BA, Berendt AR.Principles and practice of antibiotic therapy of diabetic foot infections.
Diabetes Metab Res Rev. 2000 Sep-Oct;16 Suppl 1:S42-6.
Mufson MA.Pneumococcal Pneumonia.
Curr Infect Dis Rep. 1999 Apr;1(1):57-64.
Reese RE, Betts RF: A Practical Approach to Infectious Diseases. 4th ed. Boston: Little, Brown, and Company; 1996: 251
Stefani SD, Cadore LP, Villaroel RU, Azevedo S, Machado AL. Antibiotic Selection in the Treatment of Febrile Neutropenia: Current Approach and New Directions.
Braz J Infect Dis. 1998 Jun;2(3):109-117.
Stamm WE, Hooton TM. Management of urinary tract infections in adults. N Engl J Med 1993;329:1328-1334.

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