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Infection

Pelvic Inflammatory disease Possible therapeutic alternatives
Pelvic inflammatory disease:



*Fluoroquinolones should only be used if community prevalence and risk of gonococcal infection is low (e.g less than 5%)
Common pathogens
Mild cases (Outpatient therapy)
Ceftriaxone 250mg IM x 1  PLUS
Doxycycline 100mg orally twice daily for 14 days  +/- Metronidazole 500mg orally twice or three times daily
Ceftriaxone 250mg IM x 1  PLUS
Azithromycin
1 gram orally once weekly x 2 weeks.
*Ofloxacin 400mg orally twice daily for 14 days plus Metronidazole 500mg orally twice or three times daily for 14 days. 
Hospitalized (moderate/severe):  
Cefotetan 2 grams IV q12h or Cefoxitin 2 grams IV every 6 hours  + Doxycycline 100mg orally or IV q12h   or
Clindamycin 600-900mg IV every 8 hours + gentamicin IV  + Doxycycline 100mg orally twice daily for 14 days
Ampicillin-sulbactam 3 grams IV q6h + Doxycycline 100mg q12h

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References - Infectious Disease Section

Infectious Disease References

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgement. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.
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