ALS (Amyotrophic Lateral Sclerosis)

What is it?

"Amyotrophic lateral sclerosis (ALS), often referred to as Lou Gehrig's disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the motor neurons in ALS eventually lead to their death. When the motor neurons die, the ability of the brain to initiate and control muscle movement is lost...."
This is a direct quote from the ALS Association.
For more info, please visit: http://www.alsa.org

riluzole (Rilutek ®):

MOA: Glutamate antagonist. Riluzole extends survival and/or time to tracheostomy. Recommended dose: 50 mg q12h. No increased benefit can be expected from higher daily doses, but adverse events are increased. Rilutek tablets should be taken at least an hour before, or two hours after, a meal to avoid a food-related decrease in bioavailability.
[Supplied: 50 mg tablet]

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David F. McAuley, Pharm.D., R.Ph. GlobalRPh Inc.

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